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Transfer RNA Biogenesis - Thermococcus onnurineus
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D TON_1969 ribonuclease P component K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D TON_1799 ribonuclease P component K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D TON_0146 ribonuclease P component K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D TON_1209 ribonuclease P component K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D TON_0252 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D TON_0714 RNA terminal phosphate cyclase K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D TON_0717 hypothetical protein, conserved K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D TON_0752 hypothetical protein K03231 EEF1A; elongation factor 1-alpha
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D TON_0189 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D TON_0568 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D TON_1803 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D TON_0141 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D TON_0579 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D TON_0505 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D TON_0343 aspartyl-tRNA synthetase K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D TON_1729 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_0899 alanyl-tRNA synthetase-related protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_1431 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_1757 alanyl-tRNA synthetase-related protein (C-terminus) K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_0961 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D TON_0058 truncated asparaginyl-tRNA synthetase-related protein K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D TON_0643 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D TON_0376 Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D TON_1090 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D TON_0602 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TON_0677 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D TON_1722 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D TON_0396 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D TON_0395 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D TON_0981 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D TON_1666 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D TON_0175 hypothetical protein, conserved, DUF516 family K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
D TON_1557 Hypothetical 2-methylthioadenine synthetase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D TON_0648 N2,N2-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D TON_1412 Met-10+ like protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D TON_0673 Met-10+ like protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D TON_1339 tRNA (1-methyladenosine) methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D TON_1905 hypothetical protein, conserved K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D TON_0748 hypothetical protein K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D TON_1881 hypothetical protein, conserved K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D TON_1531 hypothetical protein, conserved K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
C Psudouridine synthases
D TON_0394 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D TON_0346 tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D TON_0405 RNA-binding protein K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
C Thiolation factors
C KEOPS/EKC complex
D TON_0709 serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D TON_1634 O-Sialoglycoprotein endopeptidase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Elongator complex
D TON_1733 Hypothetical histone acetyltransferase Elp3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
C Elongator related proteins
C Other tRNA modification factors
D TON_1086 Hypothetical translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D TON_0521 RNA-binding protein K06963 TAN1; tRNA acetyltransferase TAN1
D TON_1599 RNA-binding protein K06963 TAN1; tRNA acetyltransferase TAN1
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D TON_0169 hypothetical protein, conserved K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D TON_0252 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D TON_1812 tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
B tRNA spricing factors
C tRNA splicing endonucleases
D TON_1417 archaeal tRNA-intron endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
C tRNA splicing ligases
D TON_0714 RNA terminal phosphate cyclase K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D TON_1813 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D TON_1278 RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D TON_0141 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D TON_1397 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D TON_0568 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D TON_0981 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D TON_1666 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D TON_0376 Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D TON_1803 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D TON_1729 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_0899 alanyl-tRNA synthetase-related protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_1431 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_1757 alanyl-tRNA synthetase-related protein (C-terminus) K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D TON_0677 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D TON_0579 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D TON_1090 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D TON_0602 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D TON_0685 Hypothetical protein K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D TON_0189 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D TON_0505 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D TON_0396 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D TON_0395 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D TON_1722 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D TON_0961 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D TON_0058 truncated asparaginyl-tRNA synthetase-related protein K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D TON_0175 hypothetical protein, conserved, DUF516 family K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D TON_1466 Hypothetical tRNA/rRNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D TON_1511 23S rRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D TON_0782 hypothetical protein, conserved K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D TON_0434 tRNA/rRNA cytosine-C5-methylase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D TON_0675 tRNA m1G methyltransferase K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221]
D TON_1671 Hypothetical N6-adenine-specific DNA methylase K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256]
D TON_0891 N2, N2-dimethylguanosine tRNA methyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D TON_1167 hypothetical protein, conserved K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D TON_0716 tRNA/rRNA cytosine-C5-methylase K22446 K22446; tRNA (cytosine49-C5)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D TON_0394 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D TON_0346 tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D TON_1717 ATPase K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
C KEOPS/EKC complex
D TON_0709 serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D TON_1634 O-Sialoglycoprotein endopeptidase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D TON_1258 hypothetical protein, conserved K09119 cgi121; KEOPS complex subunit Cgi121
D TON_0452 hypothetical protein, conserved K09741 pcc1; KEOPS complex subunit Pcc1
C Other tRNA modification factors
D TON_1263 Hypothetical transcription regulator K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D TON_0927 6-pyruvoyl-tetrahydropterin synthase-related protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D TON_0458 organic radical activating enzyme K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D TON_0617 archaeosine tRNA-guanine transglycosylase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D TON_1006 ThiI-related protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D TON_1008 Thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D TON_0853 Hypothetical thiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D TON_0699 nucleic acid-binding protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D TON_0968 Hypothetical ATPase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D TON_1086 Hypothetical translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024