+F Repair protein KO
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DNA Repair and Recombination Proteins - Xanthomonas campestris pv. raphani
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D XCR_3005 6-O-methylguanine-DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D XCR_1707 photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E XCR_0529 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E XCR_2721 mutY; A-G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E XCR_1806 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D XCR_3538 endonuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D XCR_0906 dgtp-pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D XCR_2432 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D XCR_0431 deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D XCR_3005 6-O-methylguanine-DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D XCR_1707 photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D XCR_1537 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E XCR_0529 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E XCR_0692 T-U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E XCR_0650 uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E XCR_0402 uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E XCR_1356 mpg; DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E XCR_3004 DNA methylation and regulatory protein Ada K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E XCR_2721 mutY; A-G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E XCR_3115 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E XCR_4482 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E XCR_3868 endonuclease K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E XCR_1806 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E XCR_0443 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E XCR_0212 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E XCR_2279 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E XCR_3072 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E XCR_2099 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E XCR_1849 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E XCR_0241 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XCR_1375 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E XCR_1297 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E XCR_2820 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
E XCR_2379 uvrC; excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
E XCR_2731 excinuclease cho K05984 cho; excinuclease Cho [EC:3.1.25.-]
E XCR_0234 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E XCR_0241 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E XCR_1849 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F XCR_1080 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F XCR_1081 rpoC; DNA-directed RNA polymerase, beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F XCR_1112 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F XCR_3588 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F XCR_3058 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E XCR_1446 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E XCR_2570 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E XCR_1829 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E XCR_2575 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E XCR_2941 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E XCR_1625 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E XCR_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E XCR_0800 DNA polymerase III holoenzyme chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E XCR_2963 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E XCR_1223 DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E XCR_1188 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E XCR_1201 DNA polymerase III subunit gamma-tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E XCR_1849 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E XCR_0234 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E XCR_3100 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E XCR_4542 exodeoxyribonuclease V beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E XCR_4543 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E XCR_4540 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E XCR_1959 recA; protein RecA K03553 recA; recombination protein RecA
E XCR_3348 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E XCR_3345 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E XCR_3349 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E XCR_0536 priA; primosomal protein N K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E XCR_1829 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E XCR_1959 recA; protein RecA K03553 recA; recombination protein RecA
E XCR_1394 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E XCR_0003 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E XCR_3578 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E XCR_2099 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E XCR_1529 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E XCR_1203 recR; recombination protein RecR K06187 recR; recombination protein RecR
E XCR_1734 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E XCR_4418 recombination associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E XCR_3348 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E XCR_3345 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E XCR_3349 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E XCR_4278 cas; crispr-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E XCR_2893 ATP-GTP-binding site motif A K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E XCR_0121 Ku protein K10979 ku; DNA end-binding protein Ku
E XCR_2579 ligD; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E XCR_0122 ligD; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F XCR_1853 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F XCR_0004 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F XCR_0550 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F XCR_0044 conserved hypothetical protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F XCR_1178 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F XCR_2099 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F XCR_1529 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F XCR_1203 recR; recombination protein RecR K06187 recR; recombination protein RecR
F XCR_1849 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F XCR_3999 DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F XCR_2771 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F XCR_2461 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F XCR_1829 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F XCR_3319 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F XCR_1375 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F XCR_1297 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F XCR_2820 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
F XCR_0786 DNA-binding protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D XCR_0734 ImpB-MucB-SamB family K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D XCR_1959 recA; protein RecA K03553 recA; recombination protein RecA
D XCR_1314 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D XCR_1958 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D XCR_1734 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D XCR_1315 conserved hypothetical protein K14160 imuA; protein ImuA
D XCR_1316 conserved hypothetical protein K14161 imuB; protein ImuB
D XCR_1318 error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D XCR_3100 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D XCR_1960 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D XCR_4474 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D XCR_0322 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D XCR_3301 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D XCR_1544 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D XCR_2590 Lhr K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D XCR_0906 dgtp-pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D XCR_2432 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D XCR_0431 deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D XCR_0280 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D XCR_0282 ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024