Chromosome and Associated Proteins - Canis lupus familiaris (dog)

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     KO
 Eukaryotic type
   Sister chromatid cohesion proteins
   Meiosis-specific proteins
   Nucleosome assembly factors
   Histone modification proteins
     HATs (histone acetyltransferases)
     HAT complexes
     HDACs (histone deacetylases)
     HDAC complexes
     HMTs (histone methyltransferases)
       HKMTs (histone lysine methyltransferases)
         480128 ASH1L; histone-lysine N-methyltransferase ASH1L
         485073 DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
         474851 EHMT2; histone-lysine N-methyltransferase EHMT2 isoform X1
         491224 EHMT1; histone-lysine N-methyltransferase EHMT1 isoform X3
         480516 EZH1; histone-lysine N-methyltransferase EZH1
         475511 EZH2; histone-lysine N-methyltransferase EZH2 isoform X6
         479417 KMT2A; histone-lysine N-methyltransferase 2A isoform X14
         486558 KMT2D; histone-lysine N-methyltransferase 2D isoform X1
         611094 KMT2C; histone-lysine N-methyltransferase 2C isoform X37
         100688666 KMT2B; histone-lysine N-methyltransferase 2B
         475895 KMT2E; LOW QUALITY PROTEIN: inactive histone-lysine N-methyltransferase 2E isoform X5
         489094 NSD1; histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1
         479077 NSD2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2
         475584 NSD3; histone-lysine N-methyltransferase NSD3 isoform X1
         100688431 PRDM2; PR domain zinc finger protein 2 isoform X1
         488148 MECOM; histone-lysine N-methyltransferase MECOM isoform X1
         100687856 PRDM6; putative histone-lysine N-methyltransferase PRDM6
         487823 PRDM8; LOW QUALITY PROTEIN: PR domain zinc finger protein 8
         489083 ZNF488; zinc finger protein 488 isoform X2
         119873358 PRDM12; PR domain zinc finger protein 12
         479582 PRDM16; histone-lysine N-methyltransferase PRDM16 isoform X1
         486257 SETD1B; histone-lysine N-methyltransferase SETD1B
         489916 SETD1A; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1A isoform X2
         476643 SETD2; histone-lysine N-methyltransferase SETD2 isoform X1
         487747 SETD4; SET domain-containing protein 4 isoform X1
         487253 SETD6; N-lysine methyltransferase SETD6 isoform X1
         476079 SETD7; histone-lysine N-methyltransferase SETD7
         610615 KMT5A; N-lysine methyltransferase KMT5A isoform X1
         483186 SETDB1; histone-lysine N-methyltransferase SETDB1 isoform X3
         485441 SETDB2; histone-lysine N-methyltransferase SETDB2 isoform X1
         476549 SETMAR; histone-lysine N-methyltransferase SETMAR
         475758 SMYD1; histone-lysine N-methyltransferase SMYD1 isoform X2
         480026 SMYD2; N-lysine methyltransferase SMYD2
         480101 SMYD3; histone-lysine N-methyltransferase SMYD3 isoform X1
         491868 SUV39H1; histone-lysine N-methyltransferase SUV39H1 isoform X1
         477995 SUV39H2; histone-lysine N-methyltransferase SUV39H2 isoform X2
         483690 KMT5B; histone-lysine N-methyltransferase KMT5B isoform X1
         484295 KMT5C; histone-lysine N-methyltransferase KMT5C isoform X1
K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354] 
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356] 
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356] 
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354] 
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354] 
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] 
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354] 
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354] 
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357] 
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357] 
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371] 
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355] 
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367] 
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-] 
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359] 
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364] 
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-] 
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364] 
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361] 
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366] 
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355] 
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
       PRMTs (protein arginine metyltransferases)
     HMT complexes
       COMPASS/SET1 complex
       COMPASS/SET1 complex (yeast)
       MLL-HCF complex
       MLL3/MLL4 complex
         611094 KMT2C; histone-lysine N-methyltransferase 2C isoform X37
         100688666 KMT2B; histone-lysine N-methyltransferase 2B
         475589 ASH2L; set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1
         475715 DPY30; protein dpy-30 homolog
         488568 RBBP5; retinoblastoma-binding protein 5 isoform X1
         608113 WDR5; WD repeat-containing protein 5
         100685660 WDR5B; WD repeat-containing protein 5B isoform X2
         477202 NCOA6; nuclear receptor coactivator 6 isoform X1
         482813 PAXIP1; PAX-interacting protein 1 isoform X2
         489939 PAGR1; PAXIP1-associated glutamate-rich protein 1
         491845 KDM6A; lysine-specific demethylase 6A isoform 1
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] 
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354] 
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2 
K14965 DPY30; protein dpy-30 
K14961 RBBP5; COMPASS component SWD1 
K14963 WDR5; COMPASS component SWD3 
K14963 WDR5; COMPASS component SWD3 
K14971 NCOA6; nuclear receptor coactivator 6 
K14972 PAXIP1; PAX-interacting protein 1 
K14973 PA1; PAXIP1-associated protein 1 
K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68] 
       Dot1-containing complex
     Histone demethylases
     Polycomb repressive complex (PRC) and associated proteins
     Sir proteins
     Other histone modification proteins
   Chromosome condensation proteins
   Centromeric chromatin formation proteins
   Heterochromatin formation proteins
   Gene silencing
   Centrosome formation proteins
   Sister chromatid separation proteins
   Chromatin remodeling factors
 
 Prokaryotic type

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Last updated: April 10, 2024