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KO |
 09100 Metabolism
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09101 Carbohydrate metabolism
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 00010 Glycolysis / Gluconeogenesis [PATH:hsa00010]
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00020 Citrate cycle (TCA cycle) [PATH:hsa00020]
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 1431 CS; citrate synthase
47 ACLY; ATP citrate lyase
50 ACO2; aconitase 2
48 ACO1; aconitase 1
3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1
3418 IDH2; isocitrate dehydrogenase (NADP(+)) 2
3420 IDH3B; isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
3421 IDH3G; isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
3419 IDH3A; isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
55753 OGDHL; oxoglutarate dehydrogenase L
4967 OGDH; oxoglutarate dehydrogenase
1743 DLST; dihydrolipoamide S-succinyltransferase
1738 DLD; dihydrolipoamide dehydrogenase
8802 SUCLG1; succinate-CoA ligase GDP/ADP-forming subunit alpha
8801 SUCLG2; succinate-CoA ligase GDP-forming subunit beta
8803 SUCLA2; succinate-CoA ligase ADP-forming subunit beta
6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
6391 SDHC; succinate dehydrogenase complex subunit C
6392 SDHD; succinate dehydrogenase complex subunit D
2271 FH; fumarate hydratase
4190 MDH1; malate dehydrogenase 1
4191 MDH2; malate dehydrogenase 2
5091 PC; pyruvate carboxylase
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
5162 PDHB; pyruvate dehydrogenase E1 subunit beta
1737 DLAT; dihydrolipoamide S-acetyltransferase
8050 PDHX; pyruvate dehydrogenase complex component X
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K01647 CS; citrate synthase [EC:2.3.3.1]
K01648 ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]
K01681 ACO; aconitate hydratase [EC:4.2.1.3]
K01681 ACO; aconitate hydratase [EC:4.2.1.3]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
K00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
K00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K01899 LSC1; succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
K01900 LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
K01900 LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K00025 MDH1; malate dehydrogenase [EC:1.1.1.37]
K00026 MDH2; malate dehydrogenase [EC:1.1.1.37]
K01958 PC; pyruvate carboxylase [EC:6.4.1.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
K13997 PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
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00030 Pentose phosphate pathway [PATH:hsa00030]
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00040 Pentose and glucuronate interconversions [PATH:hsa00040]
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00051 Fructose and mannose metabolism [PATH:hsa00051]
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00052 Galactose metabolism [PATH:hsa00052]
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00053 Ascorbate and aldarate metabolism [PATH:hsa00053]
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00500 Starch and sucrose metabolism [PATH:hsa00500]
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00520 Amino sugar and nucleotide sugar metabolism [PATH:hsa00520]
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00620 Pyruvate metabolism [PATH:hsa00620]
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00630 Glyoxylate and dicarboxylate metabolism [PATH:hsa00630]
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00640 Propanoate metabolism [PATH:hsa00640]
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00650 Butanoate metabolism [PATH:hsa00650]
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00660 C5-Branched dibasic acid metabolism
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00562 Inositol phosphate metabolism [PATH:hsa00562]
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09102 Energy metabolism
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09103 Lipid metabolism
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09104 Nucleotide metabolism
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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00410 beta-Alanine metabolism [PATH:hsa00410]
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00430 Taurine and hypotaurine metabolism [PATH:hsa00430]
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00440 Phosphonate and phosphinate metabolism [PATH:hsa00440]
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00450 Selenocompound metabolism [PATH:hsa00450]
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00460 Cyanoamino acid metabolism
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00470 D-Amino acid metabolism [PATH:hsa00470]
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00480 Glutathione metabolism [PATH:hsa00480]
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2686 GGT7; gamma-glutamyltransferase 7
124975 GGT6; gamma-glutamyltransferase 6
2678 GGT1; gamma-glutamyltransferase 1
2687 GGT5; gamma-glutamyltransferase 5
79017 GGCT; gamma-glutamylcyclotransferase
79094 CHAC1; ChaC glutathione specific gamma-glutamylcyclotransferase 1
494143 CHAC2; ChaC glutathione specific gamma-glutamylcyclotransferase 2
26873 OPLAH; 5-oxoprolinase, ATP-hydrolysing
2729 GCLC; glutamate-cysteine ligase catalytic subunit
2730 GCLM; glutamate-cysteine ligase modifier subunit
2937 GSS; glutathione synthetase
51056 LAP3; leucine aminopeptidase 3
290 ANPEP; alanyl aminopeptidase, membrane
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
2950 GSTP1; glutathione S-transferase pi 1
373156 GSTK1; glutathione S-transferase kappa 1
27306 HPGDS; hematopoietic prostaglandin D synthase
10314 LANCL1; LanC like glutathione S-transferase 1
9027 NAT8; N-acetyltransferase 8 (putative)
2936 GSR; glutathione-disulfide reductase
3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1
3418 IDH2; isocitrate dehydrogenase (NADP(+)) 2
5226 PGD; phosphogluconate dehydrogenase
2539 G6PD; glucose-6-phosphate dehydrogenase
51060 TXNDC12; thioredoxin domain containing 12
2879 GPX4; glutathione peroxidase 4
257202 GPX6; glutathione peroxidase 6
2882 GPX7; glutathione peroxidase 7
2877 GPX2; glutathione peroxidase 2
2878 GPX3; glutathione peroxidase 3
2876 GPX1; glutathione peroxidase 1
2880 GPX5; glutathione peroxidase 5
493869 GPX8; glutathione peroxidase 8 (putative)
9588 PRDX6; peroxiredoxin 6
4953 ODC1; ornithine decarboxylase 1
6723 SRM; spermidine synthase
6611 SMS; spermine synthase
6240 RRM1; ribonucleotide reductase catalytic subunit M1
50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
6241 RRM2; ribonucleotide reductase regulatory subunit M2
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K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K00682 GGCT; gamma-glutamylcyclotransferase [EC:4.3.2.9]
K07232 CHAC; glutathione-specific gamma-glutamylcyclotransferase [EC:4.3.2.7]
K07232 CHAC; glutathione-specific gamma-glutamylcyclotransferase [EC:4.3.2.7]
K01469 OPLAH; 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]
K11204 GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K11205 GCLM; glutamate--cysteine ligase regulatory subunit
K21456 GSS; glutathione synthase [EC:6.3.2.3]
K11142 LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K11140 ANPEP; aminopeptidase N [EC:3.4.11.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K25210 LANCL1; glutathione transferase [EC:2.5.1.18]
K20838 NAT8; N-acetyltransferase 8 [EC:2.3.1.80 2.3.1.-]
K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K05360 TXNDC12; protein-disulfide reductase (glutathione) [EC:1.8.4.2]
K05361 GPX4; phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K11188 PRDX6; peroxiredoxin 6 [EC:1.11.1.7 1.11.1.27 3.1.1.-]
K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
K00797 speE; spermidine synthase [EC:2.5.1.16]
K00802 SMS; spermine synthase [EC:2.5.1.22]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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09141 Transport and catabolism
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04144 Endocytosis [PATH:hsa04144]
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04145 Phagosome [PATH:hsa04145]
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04142 Lysosome [PATH:hsa04142]
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04146 Peroxisome [PATH:hsa04146]
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9409 PEX16; peroxisomal biogenesis factor 16
8504 PEX3; peroxisomal biogenesis factor 3
5824 PEX19; peroxisomal biogenesis factor 19
5825 ABCD3; ATP binding cassette subfamily D member 3
5189 PEX1; peroxisomal biogenesis factor 1
5190 PEX6; peroxisomal biogenesis factor 6
55670 PEX26; peroxisomal biogenesis factor 26
5191 PEX7; peroxisomal biogenesis factor 7
5830 PEX5; peroxisomal biogenesis factor 5
51555 PEX5L; peroxisomal biogenesis factor 5 like
5195 PEX14; peroxisomal biogenesis factor 14
5194 PEX13; peroxisomal biogenesis factor 13
5193 PEX12; peroxisomal biogenesis factor 12
5192 PEX10; peroxisomal biogenesis factor 10
5828 PEX2; peroxisomal biogenesis factor 2
5827 PXMP2; peroxisomal membrane protein 2
4358 MPV17; mitochondrial inner membrane protein MPV17
84769 MPV17L2; MPV17 mitochondrial inner membrane protein like 2
255027 MPV17L; MPV17 mitochondrial inner membrane protein like
11264 PXMP4; peroxisomal membrane protein 4
8800 PEX11A; peroxisomal biogenesis factor 11 alpha
8799 PEX11B; peroxisomal biogenesis factor 11 beta
92960 PEX11G; peroxisomal biogenesis factor 11 gamma
10478 SLC25A17; solute carrier family 25 member 17
26061 HACL1; 2-hydroxyacyl-CoA lyase 1
23600 AMACR; alpha-methylacyl-CoA racemase
5264 PHYH; phytanoyl-CoA 2-hydroxylase
8310 ACOX3; acyl-CoA oxidase 3, pristanoyl
51 ACOX1; acyl-CoA oxidase 1
8309 ACOX2; acyl-CoA oxidase 2
3295 HSD17B4; hydroxysteroid 17-beta dehydrogenase 4
6342 SCP2; sterol carrier protein 2
570 BAAT; bile acid-CoA:amino acid N-acyltransferase
1962 EHHADH; enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
30 ACAA1; acetyl-CoA acyltransferase 1
26063 DECR2; 2,4-dienoyl-CoA reductase 2
1891 ECH1; enoyl-CoA hydratase 1
215 ABCD1; ATP binding cassette subfamily D member 1
225 ABCD2; ATP binding cassette subfamily D member 2
5826 ABCD4; ATP binding cassette subfamily D member 4
11001 SLC27A2; solute carrier family 27 member 2
23305 ACSL6; acyl-CoA synthetase long chain family member 6
2182 ACSL4; acyl-CoA synthetase long chain family member 4
2180 ACSL1; acyl-CoA synthetase long chain family member 1
51703 ACSL5; acyl-CoA synthetase long chain family member 5
2181 ACSL3; acyl-CoA synthetase long chain family member 3
55825 PECR; peroxisomal trans-2-enoyl-CoA reductase
10455 ECI2; enoyl-CoA delta isomerase 2
283927 NUDT7; nudix hydrolase 7
83594 NUDT12; nudix hydrolase 12
25961 NUDT13; nudix hydrolase 13
390916 NUDT19; nudix hydrolase 19
10005 ACOT8; acyl-CoA thioesterase 8
1384 CRAT; carnitine O-acetyltransferase
54677 CROT; carnitine O-octanoyltransferase
23417 MLYCD; malonyl-CoA decarboxylase
8443 GNPAT; glyceronephosphate O-acyltransferase
8540 AGPS; alkylglycerone phosphate synthase
55711 FAR2; fatty acyl-CoA reductase 2
84188 FAR1; fatty acyl-CoA reductase 1
4598 MVK; mevalonate kinase
10654 PMVK; phosphomevalonate kinase
189 AGXT; alanine--glyoxylate aminotransferase
1610 DAO; D-amino acid oxidase
8528 DDO; D-aspartate oxidase
3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1
3418 IDH2; isocitrate dehydrogenase (NADP(+)) 2
196743 PAOX; polyamine oxidase
51268 PIPOX; pipecolic acid and sarcosine oxidase
3155 HMGCL; 3-hydroxy-3-methylglutaryl-CoA lyase
54511 HMGCLL1; 3-hydroxy-3-methylglutaryl-CoA lyase like 1
51179 HAO2; hydroxyacid oxidase 2
54363 HAO1; hydroxyacid oxidase 1
847 CAT; catalase
25824 PRDX5; peroxiredoxin 5
6647 SOD1; superoxide dismutase 1
6648 SOD2; superoxide dismutase 2
4843 NOS2; nitric oxide synthase 2
5052 PRDX1; peroxiredoxin 1
2053 EPHX2; epoxide hydrolase 2
373156 GSTK1; glutathione S-transferase kappa 1
7498 XDH; xanthine dehydrogenase
10901 DHRS4; dehydrogenase/reductase 4
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K13335 PEX16; peroxin-16
K13336 PEX3; peroxin-3
K13337 PEX19; peroxin-19
K05677 ABCD3; ATP-binding cassette, subfamily D (ALD), member 3 [EC:7.6.2.4]
K13338 PEX1; peroxin-1
K13339 PEX6; peroxin-6
K13340 PEX26; peroxin-26
K13341 PEX7; peroxin-7
K13342 PEX5; peroxin-5
K13342 PEX5; peroxin-5
K13343 PEX14; peroxin-14
K13344 PEX13; peroxin-13
K13345 PEX12; peroxin-12
K13346 PEX10; peroxin-10
K06664 PEX2; peroxin-2
K13347 PXMP2; peroxisomal membrane protein 2
K13348 MPV17; protein Mpv17
K13348 MPV17; protein Mpv17
K13349 MPV17L; Mpv17-like protein
K13350 PXMP4; peroxisomal membrane protein 4
K13351 PEX11A; peroxin-11A
K13352 PEX11B; peroxin-11B
K13353 PEX11C; peroxin-11C
K13354 SLC25A17; solute carrier family 25 (peroxisomal adenine nucleotide transporter), member 17
K12261 HACL1; 2-hydroxyacyl-CoA lyase [EC:4.1.2.63]
K01796 E5.1.99.4; alpha-methylacyl-CoA racemase [EC:5.1.99.4]
K00477 PHYH; phytanoyl-CoA hydroxylase [EC:1.14.11.18]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K10214 ACOX2; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]
K12405 HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
K08764 SCP2; sterol carrier protein 2 [EC:2.3.1.176]
K00659 BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
K07514 EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07513 ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
K13237 DECR2; 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], peroxisomal [EC:1.3.1.124]
K12663 ECH1; Delta3,5-Delta2,4-dienoyl-CoA isomerase [EC:5.3.3.21]
K05675 ABCD1; ATP-binding cassette, subfamily D (ALD), member 1 [EC:7.6.2.4]
K05676 ABCD2; ATP-binding cassette, subfamily D (ALD), member 2 [EC:7.6.2.4]
K05678 ABCD4; ATP-binding cassette, subfamily D (ALD), member 4 [EC:7.6.2.8]
K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
K13239 ECI2; Delta3-Delta2-enoyl-CoA isomerase [EC:5.3.3.8]
K17879 NUDT7; peroxisomal coenzyme A diphosphatase NUDT7 [EC:3.6.1.-]
K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]
K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]
K13355 NUDT19; nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-]
K11992 ACOT8; acyl-CoA thioesterase 8 [EC:3.1.2.27]
K00624 E2.3.1.7; carnitine O-acetyltransferase [EC:2.3.1.7]
K05940 CROT; carnitine O-octanoyltransferase [EC:2.3.1.137]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K00649 GNPAT; glyceronephosphate O-acyltransferase [EC:2.3.1.42]
K00803 AGPS; alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]
K13356 FAR; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
K13356 FAR; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
K00869 MVK; mevalonate kinase [EC:2.7.1.36]
K13273 PMVK; phosphomevalonate kinase [EC:2.7.4.2]
K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
K00273 DAO; D-amino-acid oxidase [EC:1.4.3.3]
K00272 DDO; D-aspartate oxidase [EC:1.4.3.1]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00308 PAOX; N1-acetylpolyamine oxidase [EC:1.5.3.13]
K00306 PIPOX; sarcosine oxidase / L-pipecolate oxidase [EC:1.5.3.1 1.5.3.7]
K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
K11517 HAO; (S)-2-hydroxy-acid oxidase [EC:1.1.3.15]
K11517 HAO; (S)-2-hydroxy-acid oxidase [EC:1.1.3.15]
K03781 katE; catalase [EC:1.11.1.6]
K11187 PRDX5; peroxiredoxin 5 [EC:1.11.1.24]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13279 PRDX1; peroxiredoxin 1 [EC:1.11.1.24]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K11147 DHRS4; dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]
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04140 Autophagy - animal [PATH:hsa04140]
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04138 Autophagy - yeast
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04136 Autophagy - other [PATH:hsa04136]
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04137 Mitophagy - animal [PATH:hsa04137]
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04139 Mitophagy - yeast
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04148 Efferocytosis [PATH:hsa04148]
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09143 Cell growth and death
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09144 Cellular community - eukaryotes
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09145 Cellular community - prokaryotes
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09142 Cell motility
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09150 Organismal Systems
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:hsa05200]
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05202 Transcriptional misregulation in cancer [PATH:hsa05202]
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05206 MicroRNAs in cancer [PATH:hsa05206]
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05205 Proteoglycans in cancer [PATH:hsa05205]
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05204 Chemical carcinogenesis - DNA adducts [PATH:hsa05204]
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05207 Chemical carcinogenesis - receptor activation [PATH:hsa05207]
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05208 Chemical carcinogenesis - reactive oxygen species [PATH:hsa05208]
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05203 Viral carcinogenesis [PATH:hsa05203]
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05230 Central carbon metabolism in cancer [PATH:hsa05230]
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6513 SLC2A1; solute carrier family 2 member 1
6514 SLC2A2; solute carrier family 2 member 2
2645 GCK; glucokinase
5315 PKM; pyruvate kinase M1/2
5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
5162 PDHB; pyruvate dehydrogenase E1 subunit beta
5163 PDK1; pyruvate dehydrogenase kinase 1
7157 TP53; tumor protein p53
9997 SCO2; synthesis of cytochrome C oxidase 2
6510 SLC1A5; solute carrier family 1 member 5
23410 SIRT3; sirtuin 3
9123 SLC16A3; solute carrier family 16 member 3
51548 SIRT6; sirtuin 6
4609 MYC; MYC proto-oncogene, bHLH transcription factor
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
4233 MET; MET proto-oncogene, receptor tyrosine kinase
5979 RET; ret proto-oncogene
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
4916 NTRK3; neurotrophic receptor tyrosine kinase 3
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2322 FLT3; fms related receptor tyrosine kinase 3
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
27165 GLS2; glutaminase 2
2744 GLS; glutaminase
2539 G6PD; glucose-6-phosphate dehydrogenase
3101 HK3; hexokinase 3
3098 HK1; hexokinase 1
3099 HK2; hexokinase 2
80201 HKDC1; hexokinase domain containing 1
5213 PFKM; phosphofructokinase, muscle
5214 PFKP; phosphofructokinase, platelet
5211 PFKL; phosphofructokinase, liver type
5223 PGAM1; phosphoglycerate mutase 1
5224 PGAM2; phosphoglycerate mutase 2
441531 PGAM4; phosphoglycerate mutase family member 4
160287 LDHAL6A; lactate dehydrogenase A like 6A
92483 LDHAL6B; lactate dehydrogenase A like 6B
3939 LDHA; lactate dehydrogenase A
3945 LDHB; lactate dehydrogenase B
3948 LDHC; lactate dehydrogenase C
3417 IDH1; isocitrate dehydrogenase (NADP(+)) 1
3418 IDH2; isocitrate dehydrogenase (NADP(+)) 2
57103 TIGAR; TP53 induced glycolysis regulatory phosphatase
5728 PTEN; phosphatase and tensin homolog
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
8140 SLC7A5; solute carrier family 7 member 5
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K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K04451 TP53; tumor protein p53
K23755 SCO2; protein SCO2
K05616 SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5
K11413 SIRT3; NAD-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
K08180 SLC16A3; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 3
K11416 SIRT6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K04377 MYC; Myc proto-oncogene protein
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K05101 NTRK3; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K14634 TIGAR; fructose-2,6-bisphosphatase [EC:3.1.3.46]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K13780 SLC7A5; solute carrier family 7 (L-type amino acid transporter), member 5
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05231 Choline metabolism in cancer [PATH:hsa05231]
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05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:hsa05235]
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09162 Cancer: specific types
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)