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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:hsa04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:hsa04012]
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04014 Ras signaling pathway [PATH:hsa04014]
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04015 Rap1 signaling pathway [PATH:hsa04015]
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04310 Wnt signaling pathway [PATH:hsa04310]
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04330 Notch signaling pathway [PATH:hsa04330]
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04340 Hedgehog signaling pathway [PATH:hsa04340]
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:hsa04350]
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04390 Hippo signaling pathway [PATH:hsa04390]
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04391 Hippo signaling pathway - fly
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04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
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04370 VEGF signaling pathway [PATH:hsa04370]
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04371 Apelin signaling pathway [PATH:hsa04371]
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04630 JAK-STAT signaling pathway [PATH:hsa04630]
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04064 NF-kappa B signaling pathway [PATH:hsa04064]
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3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
7535 ZAP70; zeta chain of T cell receptor associated protein kinase 70
27040 LAT; linker for activation of T cells
5335 PLCG1; phospholipase C gamma 1
5588 PRKCQ; protein kinase C theta
102723407 IGH; immunoglobulin heavy variable 4-38-2-like
6850 SYK; spleen associated tyrosine kinase
4067 LYN; LYN proto-oncogene, Src family tyrosine kinase
29760 BLNK; B cell linker
695 BTK; Bruton tyrosine kinase
5336 PLCG2; phospholipase C gamma 2
5579 PRKCB; protein kinase C beta
29775 CARD10; caspase recruitment domain family member 10
84433 CARD11; caspase recruitment domain family member 11
79092 CARD14; caspase recruitment domain family member 14
8915 BCL10; BCL10 immune signaling adaptor
10892 MALT1; MALT1 paracaspase
3553 IL1B; interleukin 1 beta
3554 IL1R1; interleukin 1 receptor type 1
4615 MYD88; MYD88 innate immune signal transduction adaptor
3654 IRAK1; interleukin 1 receptor associated kinase 1
51135 IRAK4; interleukin 1 receptor associated kinase 4
7189 TRAF6; TNF receptor associated factor 6
7124 TNF; tumor necrosis factor
7132 TNFRSF1A; TNF receptor superfamily member 1A
8737 RIPK1; receptor interacting serine/threonine kinase 1
8717 TRADD; TNFRSF1A associated via death domain
7186 TRAF2; TNF receptor associated factor 2
7188 TRAF5; TNF receptor associated factor 5
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
1896 EDA; ectodysplasin A
10913 EDAR; ectodysplasin A receptor
128178 EDARADD; EDAR associated via death domain
1540 CYLD; CYLD lysine 63 deubiquitinase
60401 EDA2R; ectodysplasin A2 receptor
23586 RIGI; RNA sensor RIG-I
7706 TRIM25; tripartite motif containing 25
3929 LBP; lipopolysaccharide binding protein
929 CD14; CD14 molecule
7099 TLR4; toll like receptor 4
23643 LY96; lymphocyte antigen 96
114609 TIRAP; TIR domain containing adaptor protein
353376 TICAM2; TIR domain containing adaptor molecule 2
148022 TICAM1; TIR domain containing adaptor molecule 1
959 CD40LG; CD40 ligand
958 CD40; CD40 molecule
7187 TRAF3; TNF receptor associated factor 3
8600 TNFSF11; TNF superfamily member 11
8792 TNFRSF11A; TNF receptor superfamily member 11a
4049 LTA; lymphotoxin alpha
4050 LTB; lymphotoxin beta
8740 TNFSF14; TNF superfamily member 14
4055 LTBR; lymphotoxin beta receptor
9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
257397 TAB3; TGF-beta activated kinase 1 (MAP3K7) binding protein 3
10673 TNFSF13B; TNF superfamily member 13b
115650 TNFRSF13C; TNF receptor superfamily member 13C
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
142 PARP1; poly(ADP-ribose) polymerase 1
51588 PIAS4; protein inhibitor of activated STAT 4
7329 UBE2I; ubiquitin conjugating enzyme E2 I
472 ATM; ATM serine/threonine kinase
55367 PIDD1; p53-induced death domain protein 1
23085 ERC1; ELKS/RAB6-interacting/CAST family member 1
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
10848 PPP1R13L; protein phosphatase 1 regulatory subunit 13 like
8837 CFLAR; CASP8 and FADD like apoptosis regulator
331 XIAP; X-linked inhibitor of apoptosis
598 BCL2L1; BCL2 like 1
596 BCL2; BCL2 apoptosis regulator
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
7185 TRAF1; TNF receptor associated factor 1
597 BCL2A1; BCL2 related protein A1
4791 NFKB2; nuclear factor kappa B subunit 2
3576 CXCL8; C-X-C motif chemokine ligand 8
7128 TNFAIP3; TNF alpha induced protein 3
5743 PTGS2; prostaglandin-endoperoxide synthase 2
6351 CCL4; C-C motif chemokine ligand 4
9560 CCL4L2; C-C motif chemokine ligand 4 like 2
388372 CCL4L1; C-C motif chemokine ligand 4 like 1
2919 CXCL1; C-X-C motif chemokine ligand 1
2920 CXCL2; C-X-C motif chemokine ligand 2
2921 CXCL3; C-X-C motif chemokine ligand 3
7412 VCAM1; vascular cell adhesion molecule 1
5328 PLAU; plasminogen activator, urokinase
1457 CSNK2A1; casein kinase 2 alpha 1
1459 CSNK2A2; casein kinase 2 alpha 2
283106 CSNK2A3; casein kinase 2 alpha 3
1460 CSNK2B; casein kinase 2 beta
5971 RELB; RELB proto-oncogene, NF-kB subunit
6357 CCL13; C-C motif chemokine ligand 13
6363 CCL19; C-C motif chemokine ligand 19
6366 CCL21; C-C motif chemokine ligand 21
6387 CXCL12; C-X-C motif chemokine ligand 12
3383 ICAM1; intercellular adhesion molecule 1
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K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K20912 CARD10; caspase recruitment domain-containing protein 10
K07367 CARD11; caspase recruitment domain-containing protein 11
K20913 CARD14; caspase recruitment domain-containing protein 14
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1; interleukin 1 receptor type I
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05480 EDA; ectodysplasin-A
K05162 EDAR; tumor necrosis factor receptor superfamily member EDAR
K23324 EDARADD; ectodysplasin-A receptor-associated adapter protein
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K05163 EDA2R; tumor necrosis factor receptor superfamily member 27
K12646 RIGI; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4; toll-like receptor 4
K05400 LY96; lymphocyte antigen 96
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K05409 TIRP; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K03161 TNFSF5; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5; tumor necrosis factor receptor superfamily member 5
K03174 TRAF3; TNF receptor-associated factor 3
K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A; tumor necrosis factor receptor superfamily member 11A
K05468 LTA; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB; lymphotoxin beta (TNF superfamily, member 3)
K05477 TNFSF14; tumor necrosis factor ligand superfamily member 14
K03159 TNFRSF3; lymphotoxin beta receptor TNFR superfamily member 3
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K12793 MAP3K7IP3; TAK1-binding protein 3
K05476 TNFSF13B; tumor necrosis factor ligand superfamily member 13B
K05151 TNFRSF13C; tumor necrosis factor receptor superfamily member 13C
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K16072 ERC1; ELKS/RAB6-interacting/CAST family member 1
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K27356 PPP1R13L; RelA-associated inhibitor
K04724 CFLAR; CASP8 and FADD-like apoptosis regulator
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K03172 TRAF1; TNF receptor-associated factor 1
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K10030 IL8; interleukin 8
K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K12964 CCL4; C-C motif chemokine 4
K12964 CCL4; C-C motif chemokine 4
K12964 CCL4; C-C motif chemokine 4
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K06527 VCAM1; vascular cell adhesion molecule 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K09253 RELB; transcription factor RelB
K16595 CCL13; C-C motif chemokine 13
K05512 CCL19; C-C motif chemokine 19
K16062 CCL21; C-C motif chemokine 21
K10031 CXCL12; C-X-C motif chemokine 12
K06490 ICAM1; intercellular adhesion molecule 1
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04668 TNF signaling pathway [PATH:hsa04668]
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04066 HIF-1 signaling pathway [PATH:hsa04066]
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04068 FoxO signaling pathway [PATH:hsa04068]
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04020 Calcium signaling pathway [PATH:hsa04020]
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04070 Phosphatidylinositol signaling system [PATH:hsa04070]
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04072 Phospholipase D signaling pathway [PATH:hsa04072]
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04071 Sphingolipid signaling pathway [PATH:hsa04071]
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04024 cAMP signaling pathway [PATH:hsa04024]
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04022 cGMP-PKG signaling pathway [PATH:hsa04022]
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04151 PI3K-Akt signaling pathway [PATH:hsa04151]
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04152 AMPK signaling pathway [PATH:hsa04152]
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04150 mTOR signaling pathway [PATH:hsa04150]
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)