 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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 K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04852 CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K08018 RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
K08052 NF1; neurofibromin 1
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04370 LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04375 ELK1; ETS domain-containing protein Elk-1
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04377 MYC; Myc proto-oncogene protein
K04378 SRF; serum response factor
K04379 FOS; proto-oncogene protein c-fos
K04380 MAPT, TAU; microtubule-associated protein tau
K04381 STMN1; stathmin 1
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04391 CD14; monocyte differentiation antigen CD14
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02308 DAXX; death-associated protein 6
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
K04406 MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K04408 MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K04411 STK4, MST1; serine/threonine kinase 4
K04412 STK3, MST2; serine/threonine kinase 3
K04414 MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K17534 MLK4, KIAA1804; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04423 MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K04424 ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04425 MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04434 MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
K04435 MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
K04436 MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
K04437 FLNA; filamin-A
K04438 CRK, CRKII; C-crk adapter molecule crk
K04439 ARRB; beta-arrestin
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04442 MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04451 TP53, P53; tumor protein p53
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K04453 MAX; Max protein
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K04455 HSPB1; heat shock protein beta-1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04457 PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
K04458 PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
K18018 PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
K18019 PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K18498 DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K17614 DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
K04460 PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
K04461 PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04014 Ras signaling pathway [PATH:ko04014]
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K08052 NF1; neurofibromin 1
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K12380 RASA3; Ras GTPase-activating protein 3
K17630 RASA4, CAPRI; Ras GTPase-activating protein 4
K17631 SYNGAP, RASA5; Ras/Rap GTPase-activating protein SynGAP
K17632 RASAL1; RAS protein activator-like 1
K17633 RASAL2; RAS protein activator-like 2
K17634 RASAL3; RAS protein activator-like 3
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K12358 FOXO4; forkhead box protein O4
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K25768 RALGAPA; Ral GTPase-activating protein subunit alpha
K25769 RALGAPB; Ral GTPase-activating protein subunit beta
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K17635 RGL1, RGL; ral guanine nucleotide dissociation stimulator-like 1
K17636 RGL2; ral guanine nucleotide dissociation stimulator-like 2
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K17637 EXOC2, SEC5; exocyst complex component 2
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09254 REL; c-Rel proto-oncogene protein
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K05702 AF6, MLLT4; afadin
K19613 SHOC2, SUR8; leucine-rich repeat protein SHOC2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K13618 PLA1A; phosphatidylserine sn-1 acylhydrolase [EC:3.1.1.111]
K01047 PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K04375 ELK1; ETS domain-containing protein Elk-1
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K17638 RIN1; Ras and Rab interactor 1
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07941 ARF6; ADP-ribosylation factor 6
|
04015 Rap1 signaling pathway [PATH:ko04015]
|
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07831 MRAS; Ras-related protein M-Ras
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K17697 DOCK4; dedicator of cytokinesis protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04270 P2RY1; P2Y purinoceptor 1
K04172 FPR1; formyl peptide receptor 1
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04266 ADORA2A, ADOR; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04438 CRK, CRKII; C-crk adapter molecule crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K06112 MAGI3; membrane-associated guanylate kinase-related
K08018 RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
K08020 RAPGEF6, PDZGEF2; Rap guanine nucleotide exchange factor 6
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07362 LAT; linker for activation of T cells family member 1
K17698 FYB, ADAP; FYN binding protein
K07361 LCP2; lymphocyte cytosolic protein 2
K17699 SKAP1, SKAP55; src kinase associated phosphoprotein 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K04145 DRD2; dopamine receptor D2
K04277 CNR1; cannabinoid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K17700 RAP1GAP, RAPGAP; RAP1 GTPase activating protein 1
K17701 SIPA1L1, E6TP1; signal-induced proliferation-associated 1 like protein 1
K08013 SIPA1; signal-induced proliferation-associated gene 1
K17702 SIPA1L2, SPAL2; signal-induced proliferation-associated 1 like protein 2
K17703 SIPA1L3, SPAL3; signal-induced proliferation-associated 1 like protein 3
K04680 ID1; DNA-binding protein inhibitor ID1
K16857 THBS1; thrombospondin 1
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K17704 APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
K06271 TLN; talin
K06476 ITGA2B, CD41; integrin alpha 2B
K06493 ITGB3, CD61; integrin beta 3
K05759 PFN; profilin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05746 ENAH, MENA; enabled
K23487 EVL; Ena/VASP-like protein
K05692 ACTB_G1; actin beta/gamma 1
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06082 FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2
K04393 CDC42; cell division control protein 42
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K05702 AF6, MLLT4; afadin
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K17705 KRIT1, CCM1; Krev interaction trapped protein 1
K17706 RGS14; regulator of G-protein signaling 14
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K05718 ITGAL, CD11a; integrin alpha L
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K05719 ITGB1, CD29; integrin beta 1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
|
04310 Wnt signaling pathway [PATH:ko04310]
|
04330 Notch signaling pathway [PATH:ko04330]
|
04340 Hedgehog signaling pathway [PATH:ko04340]
|
04341 Hedgehog signaling pathway - fly [PATH:ko04341]
|
04350 TGF-beta signaling pathway [PATH:ko04350]
|
04390 Hippo signaling pathway [PATH:ko04390]
|
04391 Hippo signaling pathway - fly [PATH:ko04391]
|
04392 Hippo signaling pathway - multiple species [PATH:ko04392]
|
04370 VEGF signaling pathway [PATH:ko04370]
|
04371 Apelin signaling pathway [PATH:ko04371]
|
04630 JAK-STAT signaling pathway [PATH:ko04630]
|
04064 NF-kappa B signaling pathway [PATH:ko04064]
|
04668 TNF signaling pathway [PATH:ko04668]
|
04066 HIF-1 signaling pathway [PATH:ko04066]
|
04068 FoxO signaling pathway [PATH:ko04068]
|
04020 Calcium signaling pathway [PATH:ko04020]
|
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K04266 ADORA2A, ADOR; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04143 ADRB3; adrenergic receptor beta-3
K04144 DRD1; dopamine receptor D1
K05840 DRD5; dopamine receptor D5
K04150 HRH2; histamine receptor H2
K04160 HTR4; 5-hydroxytryptamine receptor 4
K04161 HTR5; 5-hydroxytryptamine receptor 5
K04162 HTR6; 5-hydroxytryptamine receptor 6
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05852 PLN; phospholamban
K22642 SLN; sarcolipin
K22643 MRLN; myoregulin
K26467 ALN; another-regulin
K26468 SMIM6, ELN; endoregulin
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K23450 HRC; sarcoplasmic reticulum histidine-rich calcium-binding protein
K16059 STIM1; stromal interaction molecule 1
K18196 STIM2; stromal interaction molecule 2
K16056 ORAI1; calcium release-activated calcium channel protein 1
K16057 ORAI2; calcium release-activated calcium channel protein 2
K16058 ORAI3; calcium release-activated calcium channel protein 3
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04852 CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K05215 P2RX1; P2X purinoceptor 1
K05216 P2RX2; P2X purinoceptor 2
K05217 P2RX3; P2X purinoceptor 3
K05218 P2RX4; P2X purinoceptor 4
K05219 P2RX5; P2X purinoceptor 5
K05221 P2RX6, P2RXL1; P2X purinoceptor 6
K05220 P2RX7; P2X purinoceptor 7
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K23449 TRDN; triadin
K23468 CASQ1; calsequestrin 1
K23445 CASQ2; calsequestrin 2
K00476 ASPH; aspartate beta-hydroxylase [EC:1.14.11.16]
K04322 CYSLTR1; cysteinyl leukotriene receptor 1
K04323 CYSLTR2; cysteinyl leukotriene receptor 2
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K04166 AGTR1; angiotensin II receptor type 1
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04169 GRPR; gastrin-releasing peptide receptor
K04149 HRH1; histamine receptor H1
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
K04211 NTSR1; neurotensin receptor 1
K04229 OXTR; oxytocin receptor
K04226 AVPR1A; arginine vasopressin receptor 1A
K04227 AVPR1B; arginine vasopressin receptor 1B
K04297 LTB4R2; leukotriene B4 receptor 2
K04279 PTAFR; platelet-activating factor receptor
K04258 PTGER1; prostaglandin E receptor 1
K04260 PTGER3; prostaglandin E receptor 3
K04262 PTGFR; prostaglandin F receptor
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04222 TACR1; tachykinin receptor 1
K04223 TACR2; tachykinin receptor 2
K04224 TACR3; tachykinin receptor 3
K04264 TBXA2R; thromboxane A2 receptor
K04282 TRHR; thyrotropin-releasing hormone receptor
K04194 CCKAR; cholecystokinin A receptor
K04195 CCKBR; cholecystokinin B receptor
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K05460 HGF; hepatocyte growth factor
K23441 MST1; hepatocyte growth factor-like protein
K05452 GDNF; glial cell derived neurotrophic factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05100 MST1R, RON, CD136; macrophage-stimulating 1 receptor [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06856 IGH; immunoglobulin heavy chain
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K16896 TPCN1; two pore calcium channel protein 1
K14077 TPCN2; two pore calcium channel protein 2
K04992 MCOLN1, TRPML1; mucolipin 1
K04993 MCOLN2, TRPML2; mucolipin 2
K04994 MCOLN3, TRPML3; mucolipin 3
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K20858 MCU; calcium uniporter protein, mitochondrial
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K05865 TNNC1; troponin C, slow skeletal and cardiac muscles
K12042 TNNC2; troponin C, skeletal muscle
K02183 CALM; calmodulin
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K15590 TFEB; transcription factor EB
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K00911 ITPK; 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
|
04070 Phosphatidylinositol signaling system [PATH:ko04070]
|
04072 Phospholipase D signaling pathway [PATH:ko04072]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
04024 cAMP signaling pathway [PATH:ko04024]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; B-lymphocyte antigen CD19
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 RXRA, NR2B1; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB, C-MYB; transcriptional activator Myb
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
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04152 AMPK signaling pathway [PATH:ko04152]
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04150 mTOR signaling pathway [PATH:ko04150]
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04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
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04144 Endocytosis [PATH:ko04144]
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K07941 ARF6; ADP-ribosylation factor 6
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K13712 PIP5KL1; phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5]
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K04644 CLTA, LCA; clathrin light chain A
K04645 CLTB, LCB; clathrin light chain B
K04646 CLTC; clathrin heavy chain
K11824 AP2A; AP-2 complex subunit alpha
K11825 AP2B1; AP-2 complex subunit beta-1
K11826 AP2M1; AP-2 complex subunit mu-1
K11827 AP2S1; AP-2 complex subunit sigma-1
K12469 EHD2; EH domain-containing protein 2
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04679 MADHIP, SARA; MAD, mothers against decapentaplegic interacting protein
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K06503 TFRC, CD71; transferrin receptor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
K12470 SH3KBP1, CIN85; SH3 domain-containing kinase-binding protein 1
K11247 SH3GL; endophilin-A
K11248 SH3GLB1; endophilin-B1
K21269 SH3GLB2; endophilin-B2
K12562 AMPH; amphiphysin
K12471 EPN; epsin
K12472 EPS15; epidermal growth factor receptor substrate 15
K19366 SPG20; spartin
K10591 NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K11981 RNF41, NRDP1; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
K05632 ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K05633 WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
K12473 LDLR; low-density lipoprotein receptor
K12474 LDLRAP1, ARH; low density lipoprotein receptor adapter protein 1
K12475 DAB2; disabled homolog 2
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K19475 WIPF; WAS/WASL-interacting protein
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K09526 DNAJC6; DnaJ homolog subfamily C member 6
K18465 MRT43, SWIP; WASH complex subunit 7
K18464 RTSC, SPG8; WASH complex subunit strumpellin
K18462 FAM21; WASH complex subunit FAM21
K18461 WASH1; WAS protein family homolog 1
K18463 CCDC53; WASH complex subunit CCDC53
K10364 CAPZA; F-actin-capping protein subunit alpha
K10365 CAPZB; F-actin-capping protein subunit beta
K18467 VPS29; vacuolar protein sorting-associated protein 29
K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
K18468 VPS35; vacuolar protein sorting-associated protein 35
K17918 SNX3_12; sorting nexin-3/12
K11839 USP8, UBP5; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
K11866 STAMBP, AMSH; STAM-binding protein [EC:3.4.19.12]
K07897 RAB7A; Ras-related protein Rab-7A
K12182 HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate
K04705 STAM; signal transducing adaptor molecule
K12183 TSG101, STP22, VPS23; ESCRT-I complex subunit TSG101
K12186 FAM125; ESCRT-I complex subunit MVB12
K12187 MVB12; ESCRT-I complex subunit MVB12
K12184 VPS28; ESCRT-I complex subunit VPS28
K12185 VPS37; ESCRT-I complex subunit VPS37
K12188 SNF8, EAP30; ESCRT-II complex subunit VPS22
K12190 VPS36, EAP45; ESCRT-II complex subunit VPS36
K12189 VPS25, EAP20; ESCRT-II complex subunit VPS25
K12195 CHMP6, VPS20; charged multivesicular body protein 6
K12194 CHMP4A_B, SNF7, VPS32A_B; charged multivesicular body protein 4A/B
K24782 CHMP4C, SNF7, VPS32C; charged multivesicular body protein 4C
K12193 VPS24, CHMP3; charged multivesicular body protein 3
K12191 CHMP2A; charged multivesicular body protein 2A
K12192 CHMP2B; charged multivesicular body protein 2B
K15053 CHMP7; charged multivesicular body protein 7
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12199 VTA1, LIP5; vacuolar protein sorting-associated protein VTA1
K12197 CHMP1, VPS46, DID2; charged multivesicular body protein 1
K12198 CHMP5, VPS60; charged multivesicular body protein 5
K19476 IST1; vacuolar protein sorting-associated protein IST1
K12200 PDCD6IP, ALIX, RIM20; programmed cell death 6-interacting protein
K19367 SPG21; maspardin
K06564 IGF2R, CD222; insulin-like growth factor 2 receptor
K17917 SNX1_2; sorting nexin-1/2
K17920 SNX5_6_32; sorting nexin-5/6/32
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K02833 HRAS; GTPase HRas
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04513 RHOA; Ras homolog gene family, member A
K06751 MHC1; MHC class I antigen
K13649 FOLR; folate receptor
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K12476 EHD3; EH domain-containing protein 3
K12477 EHD4; EH domain-containing protein 4
K12478 EEA1; early endosome antigen 1
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K12480 RABEP1; Rab GTPase-binding effector protein 1
K12481 RBSN, ZFYVE20; rabenosyn-5
K07879 RAB4A, RAB4; Ras-related protein Rab-4A
K12482 RUFY1_2, RABIP4; RUN and FYVE domain-containing protein 1/2
K12483 EHD1; EH domain-containing protein 1
K12479 VPS45; vacuolar protein sorting-associated protein 45
K17919 SNX4; sorting nexin-4
K07891 RAB22; Ras-related protein Rab-22
K07903 RAB10; Ras-related protein Rab-10
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07876 RAB35, RAB1C; Ras-related protein Rab-35
K07904 RAB11A; Ras-related protein Rab-11A
K07905 RAB11B; Ras-related protein Rab-11B
K12484 RAB11FIP1_2_5; Rab11 family-interacting protein 1/2/5
K19368 ZFYVE27; protrudin
K10396 KIF5; kinesin family member 5
K12485 RAB11FIP3_4; Rab11 family-interacting protein 3/4
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K04393 CDC42; cell division control protein 42
K12486 SMAP; stromal membrane-associated protein
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K12487 GIT2; G protein-coupled receptor kinase interactor 2
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
K18439 ARAP1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
K18440 ARAP2; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K12491 AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
K12494 PSD; PH and SEC7 domain-containing protein
K12495 IQSEC; IQ motif and SEC7 domain-containing protein
K18441 CYTH; cytohesin
K18442 ARFGEF, BIG; brefeldin A-inhibited guanine nucleotide-exchange protein
K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
K07937 ARF1_2; ADP-ribosylation factor 1/2
K07938 ARF3; ADP-ribosylation factor 3
K07939 ARF4; ADP-ribosylation factor 4
K07940 ARF5; ADP-ribosylation factor 5
|
04145 Phagosome [PATH:ko04145]
|
04142 Lysosome [PATH:ko04142]
|
04146 Peroxisome [PATH:ko04146]
|
04140 Autophagy - animal [PATH:ko04140]
|
04138 Autophagy - yeast [PATH:ko04138]
|
04136 Autophagy - other [PATH:ko04136]
|
04137 Mitophagy - animal [PATH:ko04137]
|
04139 Mitophagy - yeast [PATH:ko04139]
|
04148 Efferocytosis [PATH:ko04148]
|
|
09143 Cell growth and death
|
|
09144 Cellular community - eukaryotes
|
04510 Focal adhesion [PATH:ko04510]
|
04520 Adherens junction [PATH:ko04520]
|
04530 Tight junction [PATH:ko04530]
|
04540 Gap junction [PATH:ko04540]
|
04550 Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]
|
K05419 LIF; leukemia inhibitory factor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K17846 KLF4; krueppel-like factor 4
K16796 SOX2; transcription factor SOX2 (SOX group B)
K04377 MYC; Myc proto-oncogene protein
K04364 GRB2; growth factor receptor-bound protein 2
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K10177 TBX3; T-box protein 3
K10164 NANOG; homeobox protein Nanog
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04666 NODAL; nodal
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04662 BMP4; bone morphogenetic protein 4
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K16790 SMAD5; mothers against decapentaplegic homolog 5
K16791 SMAD9, SMAD8; mothers against decapentaplegic homolog 9
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K17694 ID3; DNA-binding protein inhibitor ID3
K17695 ID4; DNA-binding protein inhibitor ID4
K18498 DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K09063 TCF3, E2A; transcription factor E2-alpha
K08553 NR3B2, ESRRB; estrogen-related receptor beta
K02620 TCF7, TCF-1; transcription factor 7
K09367 POU5F; POU domain transcription factor, class 5
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K09354 HESX1; homeobox protein expressed in ES cells 1
K18487 ZIC3; zinc finger protein ZIC 3
K04668 LEFTY; left-right determination factor
K18499 SKIL; Ski-like protein
K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
K11305 MYST3, KAT6A; histone acetyltransferase MYST3 [EC:2.3.1.48]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K11478 JARID2, JMJ; protein Jumonji
K09222 REST; RE1-silencing transcription factor
K11138 RIF1; telomere-associated protein RIF1
K11487 PCGF1, NSPC1; polycomb group RING finger protein 1
K11460 PCGF2, RNF110; polycomb group RING finger protein 2
K11488 PCGF3; polycomb group RING finger protein 3
K11459 PCGF4, BMI1; polycomb group RING finger protein 4
K11489 PCGF5; polycomb group RING finger protein 5
K11470 PCGF6, MBLR; polycomb group RING finger protein 6
K08031 PAX6; paired box protein 6
K15613 MEIS1; homeobox protein Meis1
K09301 HOX_1; homeobox protein HoxA/B/D1
K18493 LHX5; LIM homeobox protein 5
K09326 OTX1; homeobox protein OTX1
K09081 NEUROG1; neurogenin 1
K09071 HAND1; heart-and neural crest derivatives-expressed protein 1
K18489 DLX5; homeobox protein DLX5
K18484 MYF5; myogenic factor 5
K08026 ONECUT1, HNF6; one cut domain, family member 1 (hepatocyte nuclear factor 6)
K09370 ISL1; insulin gene enhancer protein ISL-1
K09378 ZFHX3, ATBF1; zinc finger homeobox protein 3
K18491 ESX1; homeobox protein ESX1
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
02030 Bacterial chemotaxis [PATH:ko02030]
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02040 Flagellar assembly [PATH:ko02040]
|
04814 Motor proteins [PATH:ko04814]
|
04820 Cytoskeleton in muscle cells [PATH:ko04820]
|
04810 Regulation of actin cytoskeleton [PATH:ko04810]
|
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05717 FN1; fibronectin 1
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05718 ITGAL, CD11a; integrin alpha L
K06461 ITGAM, CD11b; integrin alpha M
K06462 ITGAX, CD11c; integrin alpha X
K06594 ITGAD, CD11d; integrin alpha D
K06524 ITGAE, CD103; integrin alpha E
K05719 ITGB1, CD29; integrin beta 1
K06464 ITGB2, CD18; integrin beta 2
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K03898 KNG, BK; kininogen
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04132 CHRM4; muscarinic acetylcholine receptor M4
K04133 CHRM5; muscarinic acetylcholine receptor M5
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K05720 FGD1; FYVE, RhoGEF and PH domain containing 1
K05722 FGD3; FYVE, RhoGEF and PH domain containing 3
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K05729 ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K26108 RGCC, RGC32; regulator of cell cycle RGCC
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K04513 RHOA; Ras homolog gene family, member A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13710 ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K10352 MYH9s; myosin heavy chain 9/10/11/14
K05740 DIAPH1; diaphanous 1
K05741 DIAPH2; diaphanous 2
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K00921 PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05745 DIAPH3, DRF3; diaphanous 3
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05746 ENAH, MENA; enabled
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05748 WASF2; WAS protein family, member 2
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05751 ABI2; abl interactor 2
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K05753 WASF1; WAS protein family, member 1
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05759 PFN; profilin
K05760 PXN; paxillin
K08007 EZR, VIL2; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K05764 TMSB4; thymosin, beta 4
K05765 CFL; cofilin
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05700 VCL; vinculin
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
K05768 GSN; gelsolin
K05699 ACTN1_4; actinin alpha 1/4
K02085 APC; adenomatosis polyposis coli protein
K05769 ARHGEF4_29, ASEF1_2; Rho guanine nucleotide exchange factor 4/29
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09150 Organismal Systems
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:ko05200]
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K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG, BK; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05072 IL7R, CD127; interleukin 7 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1, pnt; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K08528 RARB, NR1B2; retinoic acid receptor beta
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP, PG; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K00873 PK, pyk; pyruvate kinase [EC:2.7.1.40]
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K04451 TP53, P53; tumor protein p53
K23755 SCO2; protein SCO2
K05616 SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5
K11413 SIRT3, SIR2L3; NAD-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
K08180 SLC16A3; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 3
K11416 SIRT6, SIR2L6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K04377 MYC; Myc proto-oncogene protein
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01425 glsA, GLS; glutaminase [EC:3.5.1.2]
K00036 G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00844 HK; hexokinase [EC:2.7.1.1]
K00850 pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
K01834 PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K00016 LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27]
K00031 IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]
K14634 TIGAR; fructose-2,6-bisphosphatase [EC:3.1.3.46]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K13780 SLC7A5, LAT1; solute carrier family 7 (L-type amino acid transporter), member 5
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:ko05210]
|
05212 Pancreatic cancer [PATH:ko05212]
|
05225 Hepatocellular carcinoma [PATH:ko05225]
|
05226 Gastric cancer [PATH:ko05226]
|
K22234 CDX2; homeobox protein CDX2
K10955 MUC2; mucin-2
K06811 CDH17; cadherin 17, LI cadherin
K22244 REG4; regenerating islet-derived protein 4
K05658 ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K11988 SHH; sonic hedgehog
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K08528 RARB, NR1B2; retinoic acid receptor beta
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K08734 MLH1; DNA mismatch repair protein MLH1
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K05691 CTNNA; catenin alpha
K10056 JUP, PG; junction plakoglobin
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
|
05214 Glioma [PATH:ko05214]
|
05216 Thyroid cancer [PATH:ko05216]
|
05221 Acute myeloid leukemia [PATH:ko05221]
|
05220 Chronic myeloid leukemia [PATH:ko05220]
|
05217 Basal cell carcinoma [PATH:ko05217]
|
05218 Melanoma [PATH:ko05218]
|
05211 Renal cell carcinoma [PATH:ko05211]
|
05219 Bladder cancer [PATH:ko05219]
|
05215 Prostate cancer [PATH:ko05215]
|
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05213 Endometrial cancer [PATH:ko05213]
|
05224 Breast cancer [PATH:ko05224]
|
05222 Small cell lung cancer [PATH:ko05222]
|
05223 Non-small cell lung cancer [PATH:ko05223]
|
|
09172 Infectious disease: viral
|
|
09171 Infectious disease: bacterial
|
|
09174 Infectious disease: parasitic
|
|
09163 Immune disease
|
|
09164 Neurodegenerative disease
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
|
09167 Endocrine and metabolic disease
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
01521 EGFR tyrosine kinase inhibitor resistance [PATH:ko01521]
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K18497 FGF2; fibroblast growth factor 2
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05464 GAS6; growth arrest-specific 6
K05115 AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K09408 FOXO3; forkhead box protein O3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08052 NF1; neurofibromin 1
K02159 BAX; apoptosis regulator BAX
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
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01524 Platinum drug resistance [PATH:ko01524]
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01523 Antifolate resistance [PATH:ko01523]
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01522 Endocrine resistance [PATH:ko01522]
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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01000 Enzymes [BR:ko01000]
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01001 Protein kinases [BR:ko01001]
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K04345 PKA; protein kinase A [EC:2.7.11.11]
K19584 PRKX; protein kinase X [EC:2.7.11.11]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18051 PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K11479 AURKB; aurora kinase B [EC:2.7.11.1]
K11480 AURKC; aurora kinase C [EC:2.7.11.1]
K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K19800 SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K20839 RSKL; ribosomal protein S6 kinase-like
K22008 PSK1; serine/threonine-protein kinase Psk1 [EC:2.7.11.1]
K08790 STK38, NDR; serine/threonine kinase 38 [EC:2.7.11.1]
K08791 LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08789 MAST, IREH1; MAST-subfamily protein kinase [EC:2.7.11.37]
K16309 MASTL, GW; serine/threonine-protein kinase greatwall [EC:2.7.11.36]
K12767 RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.36]
K08793 STK32, YANK; serine/threonine kinase 32 [EC:2.7.11.1]
K08788 DMPK; dystrophia myotonica-protein kinase [EC:2.7.11.1]
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
K16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K17529 SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1]
K20714 OXI1; serine/threonine-protein kinase OXI1 [EC:2.7.11.1]
K20715 PHOT; phototropin [EC:2.7.11.1]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K08795 PNCK; pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17]
K08812 CAMKV; CaM kinase-like vesicle-associated [EC:2.7.11.-]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K08797 HUNK; hormonally upregulated Neu-associated kinase [EC:2.7.11.1]
K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
K08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
K16310 NIM1; serine/threonine-protein kinase NIM1 [EC:2.7.11.1]
K08800 NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
K08801 PASK; PAS domain containing serine/threonine kinase [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
K19009 SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
K08802 SNRK; SNF related kinase [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K14498 SNRK2; serine/threonine-protein kinase SRK2 [EC:2.7.11.1]
K12761 SNF1; carbon catabolite-derepressing protein kinase [EC:2.7.11.1]
K18639 KCC4; serine/threonine-protein kinase KCC4 [EC:2.7.11.1]
K06668 GIN4; serine/threonine-protein kinase GIN4 [EC:2.7.11.-]
K02515 HSL1; serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]
K18680 CDR1; mitosis inducer protein kinase Cdr1 [EC:2.7.11.1]
K18679 CDR2; mitosis inducer protein kinase Cdr2 [EC:2.7.11.1]
K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
K17530 DCLK3; doublecortin-like kinase 3 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04442 MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12567 TTN; titin [EC:2.7.11.1]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K08807 PIM3; proto-oncogene serine/threonine-protein kinase Pim-3 [EC:2.7.11.1]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K12776 MEK1; meiosis-specific serine/threonine-protein kinase MEK1 [EC:2.7.11.1]
K08809 SPEG; striated muscle-specific serine/threonine protein kinase [EC:2.7.11.1]
K08810 TRIO; triple functional domain protein [EC:2.7.11.1]
K15048 KALRN; kalirin [EC:2.7.11.1]
K17531 OBSCN, ARHGEF30; obscurin-RhoGEF [EC:2.7.11.1]
K08811 TSSK, STK22; testis-specific serine kinase [EC:2.7.11.1]
K13412 CPK; calcium-dependent protein kinase [EC:2.7.11.1]
K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
K08814 TRIB1_2; tribbles homolog 1/2
K19518 TRIB3; tribbles homolog 3
K08813 STK33; serine/threonine kinase 33 [EC:2.7.11.1]
K16312 STK40, SHIK; serine/threonine-protein kinase 40 [EC:2.7.11.1]
K23785 RCK2, CLK1; serine/threonine-protein kinase RCK2 [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02218 CSNK1, CKI; casein kinase 1 [EC:2.7.11.1]
K19830 YCK3; casein kinase I homolog 3 [EC:2.7.11.1]
K14758 HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]
K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02088 CDK3; cyclin-dependent kinase 3 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
K08821 CDK14, PFTK1; cyclin-dependent kinase 14 [EC:2.7.11.22]
K15594 CDK15, PFTK2; cyclin-dependent kinase 15 [EC:2.7.11.22]
K08820 CDK16, PCTK1; cyclin-dependent kinase 16 [EC:2.7.11.22]
K15595 CDK17, PCTK2; cyclin-dependent kinase 17 [EC:2.7.11.22]
K15596 CDK18, PCTK3; cyclin-dependent kinase 18 [EC:2.7.11.22]
K07760 CDK; cyclin-dependent kinase [EC:2.7.11.22]
K15562 BUR1, SGV1; serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]
K00916 CTK1; CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K20535 MPK1_2; mitogen-activated protein kinase 1/2 [EC:2.7.11.24]
K20536 MPK3; mitogen-activated protein kinase 3 [EC:2.7.11.24]
K20600 MPK4; mitogen-activated protein kinase 4 [EC:2.7.11.24]
K14512 MPK6; mitogen-activated protein kinase 6 [EC:2.7.11.24]
K20537 MPK7_14; mitogen-activated protein kinase 7/14 [EC:2.7.11.24]
K20538 MPK8; mitogen-activated protein kinase 8 [EC:2.7.11.24]
K08293 SMK1; sporulation-specific mitogen-activated protein kinase SMK1 [EC:2.7.11.24]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K27413 ASK1_3_5; shaggy-related protein kinase [EC:2.7.11.1]
K27414 ASK2_8; shaggy-related protein kinase [EC:2.7.11.1]
K14502 ASK6_7_9, BIN2; shaggy-related protein kinase (protein brassinosteroid insensitive 2) [EC:2.7.11.1]
K12766 MDS1, RIM11; serine/threonine-protein kinase MDS1/RIM11 [EC:2.7.11.1]
K23561 CLK1_4; dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
K18670 YAK1; dual specificity protein kinase YAK1 [EC:2.7.12.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
K08828 ICK; intestinal cell (MAK-like) kinase [EC:2.7.11.22]
K08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]
K08830 RAGE, MOK; renal tumor antigen [EC:2.7.11.22]
K12765 IME2; meiosis induction protein kinase IME2/SME1 [EC:2.7.11.1]
K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
K08831 SRPK2; serine/threonine-protein kinase SRPK2 [EC:2.7.11.1]
K08832 SRPK3, STK23; serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K08294 MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K11226 STE7; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K11227 PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K19763 JKK1; dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2]
K20602 MEK1, MKK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K20603 MKK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K20607 MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K13413 MKK4_5; mitogen-activated protein kinase kinase 4/5 [EC:2.7.12.2]
K20604 MKK9; mitogen-activated protein kinase kinase 9 [EC:2.7.12.2]
K04408 MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04414 MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04406 MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K08833 MAP4K5, KHS1; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
K04413 MINK; misshapen/NIK-related kinase [EC:2.7.11.1]
K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
K16313 NRK; Nik-related protein kinase [EC:2.7.11.1]
K08834 MYO3, DFNB30; myosin III [EC:2.7.11.1]
K08835 OXSR1, STK39; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K19833 CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
K08836 SLK; STE20-like kinase [EC:2.7.11.1]
K08837 STK10, LOK; serine/threonine kinase 10 [EC:2.7.11.1]
K08271 STRADA, LYK5; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K04412 STK3, MST2; serine/threonine kinase 3
K04411 STK4, MST1; serine/threonine kinase 4
K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K12771 SPS1; sporulation-specific protein 1 [EC:2.7.11.1]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04425 MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K13986 MAP3K15; mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25]
K17533 MAP3K19, YSK4; mitogen-activated protein kinase kinase kinase 19 [EC:2.7.11.25]
K13414 MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K20605 MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K20606 ANP1; mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25]
K20716 MAPKKK17_18; mitogen-activated protein kinase kinase kinase 17/18
K20717 YDA; mitogen-activated protein kinase kinase kinase YODA [EC:2.7.11.25]
K11228 STE11; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K11229 BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K11230 SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K13415 BRI1; protein brassinosteroid insensitive 1 [EC:2.7.10.1 2.7.11.1]
K13416 BAK1; brassinosteroid insensitive 1-associated receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
K13417 SERK4, BKK1; somatic embryogenesis receptor kinase 4 [EC:2.7.10.1 2.7.11.1]
K13418 SERK1; somatic embryogenesis receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
K13420 FLS2; LRR receptor-like serine/threonine-protein kinase FLS2 [EC:2.7.11.1]
K13428 EFR; LRR receptor-like serine/threonine-protein kinase EFR [EC:2.7.11.1]
K20718 ER; LRR receptor-like serine/threonine-protein kinase ERECTA [EC:2.7.11.1]
K14500 BSK; BR-signaling kinase [EC:2.7.11.1]
K00924 TMK; receptor protein kinase TMK [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K08841 TESK1; testis-specific kinase 1 [EC:2.7.12.1]
K08842 TESK2; testis-specific kinase 2 [EC:2.7.12.1]
K08843 LRRK1; leucine-rich repeat kinase 1 [EC:2.7.11.1]
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K17534 MLK4, KIAA1804; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04424 ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04423 MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K17535 TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K14510 CTR1; serine/threonine-protein kinase CTR1 [EC:2.7.11.1]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K08848 RIPK4; receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1]
K16289 ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1]
K16279 KEG; E3 ubiquitin-protein ligase KEG [EC:2.7.11.1 2.3.2.27]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K08851 TP53RK, PRPK, BUD32; TP53 regulating kinase and related kinases [EC:2.7.11.1]
K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
K00908 CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K11715 ERN2; serine/threonine-protein kinase/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
K08854 BMP2K, BIKE; BMP2 inducible kinase [EC:2.7.11.1]
K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
K20873 NEK3; serine/threonine-protein kinase Nek3 [EC:2.7.11.1]
K20875 NEK6; serine/threonine-protein kinase Nek6 [EC:2.7.11.34]
K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
K20877 NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
K20878 NEK9, NERCC1; serine/threonine-protein kinase Nek9 [EC:2.7.11.1]
K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K17537 SGK223; tyrosine-protein kinase SgK223 [EC:2.7.10.2]
K17538 PEAK1, SGK269; pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2]
K08859 STK35, PDIK1, CLIK1; serine/threonine kinase 35 [EC:2.7.11.1]
K17539 PDIK1L, CLIK1L; serine/threonine-protein kinase PDIK1L [EC:2.7.11.1]
K17540 TEX14, SGK307; inactive serine/threonine-protein kinase TEX14
K08875 NRBP; nuclear receptor-binding protein
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K08876 SCYL1; SCY1-like protein 1
K17541 SCYL2; SCY1-like protein 2
K17542 SCYL3; SCY1-like protein 3
K17543 PXK; PX domain-containing protein kinase-like protein
K17544 TBCK; TBC domain-containing protein kinase-like protein
K08864 TLK; tousled-like kinase [EC:2.7.11.1]
K08865 PBK; PDZ-binding kinase [EC:2.7.12.2]
K08866 TTK, MPS1; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K06228 FU; fused [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K21358 ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
K17545 ULK4; serine/threonine-protein kinase ULK4 [EC:2.7.11.1]
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K08867 WNK, PRKWNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08869 ADCK, ABC1; aarF domain-containing kinase
K08868 ALPK; alpha-kinase
K04981 TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K08871 BRD2; bromodomain-containing protein 2
K11721 BRD3; bromodomain-containing protein 3
K11722 BRD4; bromodomain-containing protein 4
K11724 BRDT; bromodomain testis-specific protein
K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
K08880 STK19; serine/threonine kinase 19 [EC:2.7.11.1]
K08879 HSPB8; heat shock protein beta-8
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K00905 BCKDK; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4]
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
K08874 TRRAP; transformation/transcription domain-associated protein
K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
K08872 RIOK3, SUDD; RIO kinase 3 [EC:2.7.11.1]
K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K08881 TRIM24, TIF1A; tripartite motif-containing protein 24 [EC:2.3.2.27]
K08882 TRIM28, TIF1B; tripartite motif-containing protein 28 [EC:2.3.2.27]
K08883 TRIM33, TIF1G; tripartite motif-containing protein 33 [EC:2.3.2.27]
K08877 UHMK1, KIS; serine/threonine-protein kinase Kist [EC:2.7.11.1]
K11789 DCAF1, VPRBP; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
K16316 STK31, TDRD8; serine/threonine-protein kinase 31 [EC:2.7.11.1]
K17547 SGK196; glycoprotein-mannosyl O6-kinase [EC:2.7.1.183]
K16288 DSTYK, RIPK5; dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
K17546 STKLD1; serine/threonine kinase-like domain-containing protein STKLD1
K13429 CERK1; chitin elicitor receptor kinase 1
K13430 PBS1; serine/threonine-protein kinase PBS1 [EC:2.7.11.1]
K13435 PTO; serine/threonine-protein kinase Pto
K13436 PTI1; pto-interacting protein 1 [EC:2.7.11.1]
K13437 XA21; receptor kinase-like protein
K16224 FRK1; senescence-induced receptor-like serine/threonine-protein kinase
K16314 ELM1; serine/threonine-protein kinase ELM1 [EC:2.7.11.1]
K21157 SAK1; SNF1-activating kinase 1 [EC:2.7.11.1]
K21158 TOS3; serine/threonine-protein kinase TOS3 [EC:2.7.11.1]
K22009 MCK1; protein kinase MCK1
K11889 impN; type VI secretion system protein ImpN [EC:2.7.11.1]
K11912 ppkA; serine/threonine-protein kinase PpkA [EC:2.7.11.1]
K14949 pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
K22893 pknH; serine/threonine kinase PknH [EC:2.7.11.1]
K13419 pknK; serine/threonine-protein kinase PknK [EC:2.7.11.1]
K12132 prkC, stkP; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
K23472 ypkA, yopO; serine/threonine protein kinase YpkA [EC:2.7.11.1]
K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
K15486 legK1; serine/threonine-protein kinase LegK1 [EC:2.7.1.-]
K17752 rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
K04757 rsbW; serine/threonine-protein kinase RsbW [EC:2.7.11.1]
K08884 K08884; serine/threonine protein kinase, bacterial [EC:2.7.11.1]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K13594 ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04669 TGFBRX; TGF-beta receptor, other
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05100 MST1R, RON, CD136; macrophage-stimulating 1 receptor [EC:2.7.10.1]
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K05102 EPHA1, EPH; Eph receptor A1 [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05104 EPHA3, HEK, TYRO4; Eph receptor A3 [EC:2.7.10.1]
K05105 EPHA4, SEK, TYRO1; Eph receptor A4 [EC:2.7.10.1]
K05106 EPHA5, EHK1, TYRO4; Eph receptor A5 [EC:2.7.10.1]
K05107 EPHA6, EHK2; Eph receptor A6 [EC:2.7.10.1]
K05108 EPHA7, EHK3, HEK11; EphA7 [EC:2.7.10.1]
K05109 EPHA8, EEK; Eph receptor A8 [EC:2.7.10.1]
K08897 EPHA10; Eph receptor A10 [EC:2.7.10.1]
K05110 EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
K05111 EPHB2, ERK, DRT; Eph receptor B2 [EC:2.7.10.1]
K05112 EPHB3, HEK2, ETK2; Eph receptor B3 [EC:2.7.10.1]
K05113 EPHB4, HTK; Eph receptor B4 [EC:2.7.10.1]
K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
K05115 AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05116 TYRO3, RSE; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]
K05117 MERTK, MER; c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K05118 LTK; leukocyte tyrosine kinase [EC:2.7.10.1]
K05120 TIE1; tyrosine kinase receptor 1 [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05122 ROR1, NTRKR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
K05123 ROR2, NTRKR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
K05124 DDR1, NEP, CD167a; discoidin domain receptor family member 1 [EC:2.7.10.1]
K05125 DDR2, TKT, CD167b; discoidin domain receptor family member 2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
K05127 PTK7, CCK4; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
K17480 AATK, LMTK1; lemur tyrosine kinase 1 [EC:2.7.10.1]
K08898 LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
K08899 LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K08885 TNK1; non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2]
K08886 TNK2, ACK1; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K07527 FES, FPS; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
K08889 FER, TYK3; tyrosine-protein kinase Fer [EC:2.7.10.2]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K08890 BLK; B lymphoid tyrosine kinase [EC:2.7.10.2]
K08891 FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
K08892 FRK, PTK5; fyn-related kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K08894 PTK6, BRK; protein tyrosine kinase 6 [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K08895 SRMS; tyrosine-protein kinase Srms [EC:2.7.10.2]
K05705 YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
K17511 YRK; proto-oncogene tyrosine-protein kinase YRK [EC:2.7.10.2]
K08896 BMX, ETK; cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K08016 TXK, RLK; tyrosine-protein kinase TXK [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
K17510 STYK1; tyrosine-protein kinase STYK1 [EC:2.7.10.2]
K17548 PKDCC; extracellular tyrosine-protein kinase PKDCC [EC:2.7.10.2]
K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
K16554 exoP, vpsO; polysaccharide biosynthesis transport protein [EC:2.7.10.3]
K00903 epsB, capB; protein-tyrosine kinase [EC:2.7.10.3]
K25588 K25588; tyrosine-protein kinase [EC:2.7.10.3]
K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
K07650 cssS; two-component system, OmpR family, sensor histidine kinase CssS [EC:2.7.13.3]
K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
K07642 baeS, smeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
K07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
K07644 cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
K07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
K07653 mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
K07654 mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
K07655 prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
K07656 trcS; two-component system, OmpR family, sensor histidine kinase TrcS [EC:2.7.13.3]
K11328 nrsS, rppB; two-component system, OmpR family, Ni(II)-sensor and/or redox sensor kinase NrsS [EC:2.7.13.3]
K11520 manS; two-component system, OmpR family, manganese sensing sensor histidine kinase [EC:2.7.13.3]
K07769 nblS, dfr, dspA, hik33; two-component system, OmpR family, sensor histidine kinase NblS [EC:2.7.13.3]
K08479 sasA; two-component system, OmpR family, clock-associated histidine kinase SasA [EC:2.7.13.3]
K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]
K11629 bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]
K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3]
K19081 braS, bceS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
K11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]
K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
K18345 vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
K18350 vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
K18351 vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
K19609 pfeS, pirS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]
K20487 nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]
K07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]
K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
K07678 barA, gacS, varS; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
K07679 evgS, bvgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
K07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
K07681 vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3]
K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
K07682 devS; two-component system, NarL family, sensor histidine kinase DevS [EC:2.7.13.3]
K27105 dosT; two-component system, NarL family, sensor histidine kinase DosT [EC:2.7.13.3]
K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
K11623 ydfH; two-component system, NarL family, sensor histidine kinase YdfH [EC:2.7.13.3]
K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]
K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
K07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]
K07698 kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]
K13532 kinD; two-component system, sporulation sensor kinase D [EC:2.7.13.3]
K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
K07700 dpiB, citA; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
K11637 citS; two-component system, CitB family, sensor histidine kinase CitS [EC:2.7.13.3]
K07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]
K11691 K11691, dctS; two-component system, CitB family, sensor histidine kinase DctS [EC:2.7.13.3]
K11614 yufL, malK; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]
K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
K11640 natK; two-component system, LytTR family, sensor histidine kinase NatK [EC:2.7.13.3]
K07706 agrC, blpH, fsrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K20339 agrC2; two-component system, LytTR family, sensor histidine kinase AgrC2 [EC:2.7.13.3]
K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3]
K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
K07708 glnL, ntrB; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
K07709 zraS, hydH; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
K02668 pilS, pehS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
K07711 glrK, qseE; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
K08475 pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]
K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
K19661 hupT, hoxJ; two-component system, NtrC family, sensor histidine kinase HupT/HoxJ [EC:2.7.13.3]
K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
K11526 pixL; two-component system, chemotaxis family, sensor histidine kinase and response regulator PixL
K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
K11357 divJ; two-component system, cell cycle sensor histidine kinase DivJ [EC:2.7.13.3]
K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
K02489 hk1; two-component system, glycerol uptake and utilization sensor kinase [EC:2.7.13.3]
K10909 luxQ; two-component system, autoinducer 2 sensor kinase/phosphatase LuxQ [EC:2.7.13.3 3.1.3.-]
K10916 cqsS; two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
K15850 luxN; two-component system, autoinducer 1 sensor kinase/phosphatase LuxN [EC:2.7.13.3 3.1.3.-]
K11711 dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]
K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
K14978 ssrA; two-component system, LuxR family, secretion system sensor histidine kinase SsrA
K10942 flrB, fleS, flaL; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
K11231 SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
K19690 CHK1; osomolarity two-component system, sensor histidine kinase CHK1 [EC:2.7.13.3]
K19691 NIK1, TCSC; osomolarity two-component system, sensor histidine kinase NIK1 [EC:2.7.13.3]
K19692 TCSA; osomolarity two-component system, sensor histidine kinase TcsA [EC:2.7.13.3]
K10715 rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
K07717 glnK; two-component system, sensor histidine kinase GlnK [EC:2.7.13.3]
K25212 hptS; two-component system, sensor histidine kinase HptS [EC:2.7.13.3]
K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
K11356 cikA; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
K15011 regB, regS, actS; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
K19616 fitF; two-component system, sensor histidine kinase and response regulator FitF [EC:2.7.13.3]
K19621 phcS; two-component system, sensor histidine kinase PhcS [EC:2.7.13.3]
K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
K19694 chiS; two-component system, sensor histidine kinase ChiS
K20971 ladS; two-component system, sensor histidine kinase LadS
K20972 retS; two-component system, sensor histidine kinase RetS
K02486 K02486; two-component system, sensor kinase [EC:2.7.13.3]
K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
|
01009 Protein phosphatases and associated proteins [BR:ko01009]
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01002 Peptidases and inhibitors [BR:ko01002]
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01003 Glycosyltransferases [BR:ko01003]
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01005 Lipopolysaccharide biosynthesis proteins [BR:ko01005]
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01011 Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
|
01004 Lipid biosynthesis proteins [BR:ko01004]
|
01008 Polyketide biosynthesis proteins [BR:ko01008]
|
01006 Prenyltransferases [BR:ko01006]
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01007 Amino acid related enzymes [BR:ko01007]
|
00199 Cytochrome P450 [BR:ko00199]
|
00194 Photosynthesis proteins [BR:ko00194]
|
|
09182 Protein families: genetic information processing
|
|
09183 Protein families: signaling and cellular processes
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02000 Transporters [BR:ko02000]
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02044 Secretion system [BR:ko02044]
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02042 Bacterial toxins [BR:ko02042]
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02022 Two-component system [BR:ko02022]
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02035 Bacterial motility proteins [BR:ko02035]
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03037 Cilium and associated proteins [BR:ko03037]
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04812 Cytoskeleton proteins [BR:ko04812]
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04147 Exosome [BR:ko04147]
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02048 Prokaryotic defense system [BR:ko02048]
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04030 G protein-coupled receptors [BR:ko04030]
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04050 Cytokine receptors [BR:ko04050]
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04054 Pattern recognition receptors [BR:ko04054]
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03310 Nuclear receptors [BR:ko03310]
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04040 Ion channels [BR:ko04040]
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04031 GTP-binding proteins [BR:ko04031]
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04052 Cytokines and neuropeptides [BR:ko04052]
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04515 Cell adhesion molecules [BR:ko04515]
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04090 CD molecules [BR:ko04090]
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K06448 CD1; T-cell surface glycoprotein CD1
K06449 CD2; T-cell surface glycoprotein CD2
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06454 CD4; T-cell surface glycoprotein CD4
K06455 CD5; T-cell surface glycoprotein CD5
K06456 CD6; T-cell surface glycoprotein CD6
K06457 CD7; T-cell surface glycoprotein CD7
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06460 CD9, TSPAN29; CD9 antigen
K01389 MME, CD10; neprilysin [EC:3.4.24.11]
K05718 ITGAL, CD11a; integrin alpha L
K06461 ITGAM, CD11b; integrin alpha M
K06462 ITGAX, CD11c; integrin alpha X
K06594 ITGAD, CD11d; integrin alpha D
K11140 ANPEP, CD13; aminopeptidase N [EC:3.4.11.2]
K04391 CD14; monocyte differentiation antigen CD14
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K06464 ITGB2, CD18; integrin beta 2
K06465 CD19; B-lymphocyte antigen CD19
K06466 MS4A1, CD20; B-lymphocyte antigen CD20
K04012 CR2, CD21; complement receptor type 2
K06467 CD22, SIGLEC2; CD22 antigen
K06468 FCER2, CD23; low affinity immunoglobulin epsilon Fc receptor
K06469 CD24; CD24 antigen
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K01278 DPP4, CD26; dipeptidyl-peptidase 4 [EC:3.4.14.5]
K05144 TNFRSF7, CD27; tumor necrosis factor receptor superfamily member 7
K06470 CD28; CD28 antigen
K05719 ITGB1, CD29; integrin beta 1
K05145 TNFRSF8, CD30; tumor necrosis factor receptor superfamily member 8
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06473 CD33, SIGLEC3; CD33 antigen
K06474 CD34; CD34 antigen
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K06259 CD36; CD36 antigen
K06475 CD37, TSPAN26; CD37 antigen
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K01510 ENTPD1_3_8, CD39; apyrase [EC:3.6.1.5]
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K06476 ITGA2B, CD41; integrin alpha 2B
K06263 GP9, CD42a; platelet glycoprotein IX
K06261 GP1BA, CD42b; platelet glycoprotein Ib alpha chain
K06262 GP1BB, CD42c; platelet glycoprotein Ib beta chain
K06260 GP5, CD42d; platelet glycoprotein V
K06477 SPN, CD43; sialophorin
K06256 CD44; CD44 antigen
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K04007 CD46, MCP; membrane cofactor protein
K06266 CD47; CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
K06479 CD48, BCM1; CD48 antigen
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06486 ICAM3, CD50; intercellular adhesion molecule 3
K06487 ITGAV, CD51; integrin alpha V
K06488 CD52; CDW52 antigen
K06489 CD53, MOX44, TSPAN25; CD53 antigen
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K04006 DAF, CD55; decay accelerating factor
K06491 NCAM, CD56; neural cell adhesion molecule
K06492 CD58, LFA3; CD58 antigen
K04008 CD59; CD59 antigen
K06493 ITGB3, CD61; integrin beta 3
K06494 SELE, CD62E; selectin, endothelial cell
K06495 SELL, CD62L; selectin, lymphocyte
K06496 SELP, CD62P; selectin, platelet
K06497 CD63, MLA1, TSPAN30; CD63 antigen
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06499 CEACAM, CD66; carcinoembryonic antigen-related cell adhesion molecule
K06500 PSG, CD66f; pregnancy specific beta-1-glycoprotein
K06501 CD68; CD68 antigen
K06502 CD69; CD69 antigen
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K06503 TFRC, CD71; transferrin receptor
K06504 CD72; CD72 antigen
K19970 NT5E, CD73; 5'-nucleotidase [EC:3.1.3.5]
K06505 CD74, DHLAG; CD74 antigen
K06506 CD79A, IGA; CD79A antigen
K06507 CD79B, IGB; CD79B antigen
K05412 CD80; CD80 antigen
K06508 CD81, TAPA1, TSPAN28; CD81 antigen
K06509 KAI1, CD82, TSPAN27; CD82 antigen
K06510 CD83; CD83 antigen
K06511 CD84; CD84 antigen
K06512 LILR, CD85; leukocyte immunoglobulin-like receptor
K05413 CD86; CD86 antigen
K03985 PLAUR, CD87; plasminogen activator, urokinase receptor
K04010 C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
K06513 FCAR, CD89; CD89 antigen
K06514 THY1, CD90; Thy-1 cell surface antigen
K04550 LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
K06515 SLC44A1, CD92; solute carrier family 44 (choline transporter-like protein), member 1
K06702 CD93; CDW93 antigen
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K06517 CD96; CD96 antigen
K08446 ADGRE5, CD97; CD97 antigen
K06519 SLC3A2, MDU1, CD98; solute carrier family 3, member 2
K06520 CD99, MIC2; CD99 antigen
K06521 SEMA4, CD100; semaphorin 4
K06522 IGSF2_3, CD101; immunoglobulin superfamily, member 2/3
K06523 ICAM2, CD102; intercellular adhesion molecule 2
K06524 ITGAE, CD103; integrin alpha E
K06525 ITGB4, CD104; integrin beta 4
K06526 ENG, CD105; endoglin
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K06528 LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
K06529 SEMA7, CD108; semaphorin 7
K06530 CD109; CD109 antigen
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K06081 NECTIN1, PVRL1, CD111; poliovirus receptor-related protein 1
K06531 PVRL2, CD112; poliovirus receptor-related protein 2
K06592 PVRL3, CD113; poliovirus receptor-related protein 3
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05132 IFNGR1, CD119; interferon gamma receptor 1
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K05069 IL2RB, CD122; interleukin 2 receptor beta
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K06532 PROM1, CD133; prominin 1
K05142 TNFRSF4, OX40, CD134; tumor necrosis factor receptor superfamily member 4
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05100 MST1R, RON, CD136; macrophage-stimulating 1 receptor [EC:2.7.10.1]
K05146 TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
K06257 SDC1, CD138; syndecan 1
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K03907 THBD, CD141; thrombomodulin
K03901 F3, CD142; coagulation factor III (tissue factor)
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K06534 MCAM, CD146; melanoma cell adhesion molecule
K06535 BSG, CD147; basigin
K05698 PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
K06536 SLAMF1, CD150; signaling lymphocytic activation molecule family member 1
K06537 CD151, TSPAN24; CD151 antigen
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K06539 PVR, NECL5, CD155; poliovirus receptor
K06540 ADAM8, CD156a; disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-]
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K06704 ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K18152 BST1, CD157; ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20]
K07981 KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
K24231 KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
K07980 KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
K24232 KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
K07982 KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
K06541 KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
K24233 KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
K06542 CD160; CD160 antigen
K06543 KLRB, CD161; killer cell lectin-like receptor subfamily B
K06544 SELPLG, CD162; selectin P ligand
K06545 CD163; CD163 antigen
K06546 CD164, MGC24; CD164 antigen
K06547 ALCAM, CD166; activated leukocyte cell adhesion molecule
K05124 DDR1, NEP, CD167a; discoidin domain receptor family member 1 [EC:2.7.10.1]
K05125 DDR2, TKT, CD167b; discoidin domain receptor family member 2 [EC:2.7.10.1]
K06267 HMMR, RHAMM, CD168; hyaluronan-mediated motility receptor
K06548 SN, SIGLEC1, CD169; sialoadhesin
K06549 SIGLEC5, CD170; sialic acid binding Ig-like lectin 5
K06550 L1CAM, CD171; L1 cell adhesion molecule
K06551 SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
K06552 CD177, PRV1; CD177 antigen
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K06553 VPREB, CD179a; pre-B lymphocyte gene
K06554 IGLL1, IGLL, CD179b; immunoglobulin lambda-like polypeptide 1
K06555 CD180; CD180 antigen
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04191 CXCR6, CD186; C-X-C chemokine receptor type 6
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04177 CCR2, CD192; C-C chemokine receptor type 2
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K06556 CD200; CD200 antigen
K06557 PROCR, CD201; protein C receptor, endothelial (EPCR)
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K01513 ENPP1_3, CD203; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K06558 MSR1, CD204; macrophage scavenger receptor 1
K06559 LY75, CD205; lymphocyte antigen 75
K06560 MRC, CD206, CD280; mannose receptor, C type
K06561 CD207; CD207 antigen
K06562 LAMP3, CD208; lysosomal-associated membrane protein 3
K06563 CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05164 IL17RA, CD217; interleukin 17 receptor A
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K06564 IGF2R, CD222; insulin-like growth factor 2 receptor
K06565 LAG3, CD223; lymphocyte-activation gene 3 protein
K18592 GGT1_5, CD224; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K19831 IFITM1, CD225; interferon induced transmembrane protein 1
K06567 CD226, DNAM1; CD226 antigen
K06568 MUC1, CD227; mucin-1
K06569 MFI2, CD228; melanoma-associated antigen p97
K06570 LY9, CD229; lymphocyte antigen 9
K05634 PRNP, PrP, CD230; prion protein
K06571 TSPAN7, TM4SF2, MXS1, CD231; tetraspanin-7
K06572 PLXNC, CD232; plexin C
K06573 SLC4A1, AE1, CD233; solute carrier family 4 (anion exchanger), member 1
K06574 ACKR1, DARC, CD234; atypical chemokine receptor 1
K06575 GYPA, CD235a; glycophorin A
K20925 GYPB, CD235b; glycophorin B
K06576 GYPC, CD236; glycophorin C
K06577 KEL, CD238; Kell blood group glycoprotein [EC:3.4.24.-]
K06578 LU, CD239; Lutheran blood group glycoprotein
K06579 RH, CD240; Rhesus blood group glycoprotein
K06580 SLC42A, RHAG, RHBG, RHCG, CD241; ammonium transporter Rh
K06581 ICAM4, CD242; intercellular adhesion molecule 4
K05658 ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K06582 CD244; natural killer cell receptor 2B4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06706 CD248, CD164L1; CD248 antigen, endosialin
K11141 ENPEP, CD249; glutamyl aminopeptidase [EC:3.4.11.7]
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K22701 TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
K22702 TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05149 TNFRSF12A, FN14, TWEAKR, CD266; tumor necrosis factor receptor superfamily member 12A
K05150 TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K05153 TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K06707 BTLA, CD272; B- and T-lymphocyte attenuator
K06708 PDCD1LG2, CD273; programmed cell death 1 ligand 2
K06745 PDL1, CD274; programmed cell death 1 ligand 1
K06710 ICOSLG, ICOSL, CD275; inducible T-cell co-stimulator ligand
K06746 B7H3, CD276; immune costimulatory protein B7-H3
K06712 BTN, CD277; butyrophilin
K06713 ICOS, AILIM, CD278; inducible T-cell co-stimulator
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K05398 TLR1, CD281; toll-like receptor 1
K10159 TLR2, CD282; toll-like receptor 2
K05401 TLR3, CD283; toll-like receptor 3
K10160 TLR4, CD284; toll-like receptor 4
K10169 TLR6, CD286; toll-like receptor 6
K10170 TLR8, CD288; toll-like receptor 8
K10161 TLR9, CD289; toll-like receptor 9
K10171 TLR10, CD290; toll-like receptor 10
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K06715 PTGDR2, GPR44, CD294; prostaglandin D2 receptor 2
K05062 LEPR, CD295; leptin receptor
K06716 ART1, CD296; ADP-ribosyltransferase 1 [EC:2.4.2.31]
K06717 ART4, DO, CD297; ADP-ribosyltransferase 4 [EC:2.4.2.31]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K06719 CD300; CD300 antigen
K06721 CLEC10A, CLECSF13, CLECSF14, CD301; C-type lectin domain family 10 member A
K06722 CD302; CD302 antigen
K06723 CLEC4C, CLECSF11, CLECSF7, CD303; C-type lectin domain family 4 member C
K06724 NRP1, CD304; neuropilin 1
K06725 LAIR, CD305_6; leukocyte-associated Ig-like receptor
K06727 FCRL, IRTA, CD307; Fc receptor-like protein
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K08443 ADGRE2, EMR2, CD312; adhesion G protein-coupled receptor E2
K06728 KLRK1, CD314; killer cell lectin-like receptor subfamily K member 1
K06729 PTGFRN, CD315; prostaglandin F2 receptor negative regulator
K06730 IGSF8, CD316; immunoglobulin superfamily, member 8
K06731 BST2, CD317; bone marrow stromal cell antigen 2
K06732 CDCP1, CD318; CUB domain-containing protein 1
K06733 SLAMF7, CD319; SLAM family member 7
K06734 CD320; CD320 antigen
K06089 F11R, JAM1, CD321; junctional adhesion molecule 1
K06735 JAM2, CD322; junctional adhesion molecule 2
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K06736 CDH2, CDHN, CD325; cadherin 2, type 1, N-cadherin
K06737 EPCAM, TACSTD1, CD326; epithelial cell adhesion molecule
K06738 SIGLEC6, CD327; sialic acid binding Ig-like lectin 6
K06739 SIGLEC7, CD328; sialic acid binding Ig-like lectin 7
K06740 SIGLEC9, CD329; sialic acid binding Ig-like lectin 9
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K06741 NCR1, CD335; natural cytotoxicity triggering receptor 1
K06742 NCR2, CD336; natural cytotoxicity triggering receptor 2
K06743 NCR3, CD337; natural cytotoxicity triggering receptor 3
K05681 ABCG2, CD338; ATP-binding cassette, subfamily G (WHITE), member 2
K06052 JAG1, CD339; jagged-1
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K02354 FZD4, fz4, CD344; frizzled 4
K02842 FZD9_10, CD349_50; frizzled 9/10
K16851 FCAMR, CD351; high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
K16852 SLAMF6, CD352; SLAM family member 6
K16853 SLAMF8, CD353; SLAM family member 8
K14362 TREM1, CD354; triggering receptor expressed on myeloid cells 1
K16361 CRTAM, CD355; cytotoxic and regulatory T-cell molecule
K05154 TNFRSF18, GITR, CD357; tumor necrosis factor receptor superfamily member 18
K05157 TNFRSF21, DR6, CD358; tumor necrosis factor receptor superfamily member 21
K05075 IL21R, CD360; interleukin 21 receptor
K16854 EVI2B, CD361; ecotropic viral integration site 2B protein
K16336 SDC2, CD362; syndecan 2
K04288 S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
K20412 PI16, CRISP9, CD364; peptidase inhibitor 16
K20413 HAVCR1, CD365; hepatitis A virus cellular receptor 1
K20414 HAVCR2, CD366; hepatitis A virus cellular receptor 2
K10057 CLEC4A, CD367; C-type lectin domain family 4 member A
K10058 CLEC4D, MCL, CD368; C-type lectin domain family 4 member D
K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K17515 CLEC9A, CD370; C-type lectin domain family 9 member A
K17516 CLEC12A, CD371; C-type lectin domain family 12 member A
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01504 Antimicrobial resistance genes [BR:ko01504]
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00535 Proteoglycans [BR:ko00535]
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00536 Glycosaminoglycan binding proteins [BR:ko00536]
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K04519 IL1B; interleukin 1 beta
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05431 IL7; interleukin 7
K05443 IL10, CSIF; interleukin 10
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12499 CCL5; C-C motif chemokine 5
K16595 CCL13; C-C motif chemokine 13
K05407 PF4, CXCL4; platelet factor 4
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K10031 CXCL12; C-X-C motif chemokine 12
K06495 SELL, CD62L; selectin, lymphocyte
K06496 SELP, CD62P; selectin, platelet
K06461 ITGAM, CD11b; integrin alpha M
K06491 NCAM, CD56; neural cell adhesion molecule
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K16621 BMP7; bone morphogenetic protein 7
K06224 HH; hedgehog
K11988 SHH; sonic hedgehog
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K09782 AREG; amphiregulin
K09783 BTC; betacellulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K08523 HBEGF; heparin-binding EGF-like growth factor
K05460 HGF; hepatocyte growth factor
K06828 MDK; midkine
K13769 IGF2; insulin-like growth factor 2
K05455 NRG1; neuregulin 1
K16641 HDGF; hepatoma-derived growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K16642 PTN; pleiotrophin
K05448 VEGFA; vascular endothelial growth factor A
K25640 MPIG6B; megakaryocyte and platelet inhibitory receptor G6b
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K05717 FN1; fibronectin 1
K06825 FBN1; fibrillin 1
K23342 FBN2_3; fibrillin 2/3
K06252 TN; tenascin
K24354 SMOC; SPARC-related modular calcium-binding protein
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K06251 VTN; vitronectin
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
K06238 COL6A; collagen type VI alpha
K16617 COL13A; collagen type XIII alpha
K06823 COL18A; collagen type XVIII alpha
K24340 COL19A; collagen type XIX alpha
K24355 COL23A; collagen type XXIII alpha
K24356 COL25A; collagen type XXV alpha
K26586 COLQ; acetylcholinesterase collagenic tail peptide
K05462 EFNA; ephrin-A
K06843 NTN1; netrin 1
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K01314 F10; coagulation factor X [EC:3.4.21.6]
K03913 SERPINA5, PCI; protein C inhibitor
K03911 SERPINC1, AT3; antithrombin III
K03912 SERPIND1, HCF2; heparin cofactor II
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K16643 SERPINE2; glia-derived nexin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03909 TFPI; tissue factor pathway inhibitor
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K19252 VP1; Dependoparvovirus capsid protein VP1/VP2/VP3
K19255 gB; Herpesviridae envelope glycoprotein B
K19256 gC; Simplexvirus envelope glycoprotein C
K19264 gD; Simplexvirus envelope glycoprotein D
K19257 gM, UL10; Herpesviridae envelope glycoprotein M
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K19287 env, gp160; HIV envelope glycoprotein gp160
K24266 gp120; HIV envelope glycoprotein gp120
K19258 tat; HIV protein Tat
K19259 env; Deltaretrovirus envelope glycoprotein gp62
K24862 gp46; HTLV envelope surface glycoprotein gp46
K19288 p130; Alphavirus structral polyprotein
K19260 L1; Papillomaviridae major capsid protein L1
K19261 F; Pneumoviridae fusion glycoprotein F0
K19262 L5; Mastadenovirus fiber protein
K19263 A27L; Orthopoxvirus protein A27
K13836 CSP; circumsporozoite protein
K15125 fhaB; filamentous hemagglutinin
K16644 actA; actin-assembly inducing protein
K16645 hbhA; heparin binding hemagglutinin HbhA
K16631 ANG, RNASE5; angiogenin [EC:3.1.27.-]
K16646 ANXA5; annexin A5
K09025 APOA5; apolipoprotein A-V
K14462 APOB; apolipoprotein B
K04524 APOE; apolipoprotein E
K04520 APP; amyloid beta A4 protein
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K05634 PRNP, PrP, CD230; prion protein
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K06256 CD44; CD44 antigen
K06267 HMMR, RHAMM, CD168; hyaluronan-mediated motility receptor
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10077 LAYN; layilin
K19012 LYVE1; lymphatic vessel endothelial hyaluronan receptor 1
K19020 STAB1; stabilin-1
K19013 STAB2, HARE; stabilin-2
K19031 CEMIP, KIAA1199; cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]
K22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]
K06792 AGC1, CSPG1; aggrecan 1
K06795 BCAN; brevican
K15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
K06848 HAPLN1, CRTL1; hyaluronan and proteoglycan link protein 1
K06851 HAPLN2; hyaluronan and proteoglycan link protein 2
K06853 HAPLN4; hyaluronan and proteoglycan link protein 4
K18977 HPX; hemopexin
K19014 ITIH1, SHAP; inter-alpha-trypsin inhibitor heavy chain H1
K19015 ITIH2, SHAP; inter-alpha-trypsin inhibitor heavy chain H2
K24513 ITIH3, SHAP; inter-alpha-trypsin inhibitor heavy chain H3
K06794 NCAN, CSPG3; neurocan core protein
K19016 IMPG1, SPACR; interphotoreceptor matrix proteoglycan 1
K19017 IMPG2, SPACRCAN; interphotoreceptor matrix proteoglycan 2
K19018 TNFAIP6, TSG6; tumor necrosis factor-inducible gene 6 protein
K06793 VCAN, CSPG2; versican core protein
K09554 CDC37; cell division cycle protein 37
K19019 HABP4; intracellular hyaluronan-binding protein 4
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
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04091 Lectins [BR:ko04091]
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04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)