 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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 K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04852 CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K08018 RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
K08052 NF1; neurofibromin 1
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04370 LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04375 ELK1; ETS domain-containing protein Elk-1
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04377 MYC; Myc proto-oncogene protein
K04378 SRF; serum response factor
K04379 FOS; proto-oncogene protein c-fos
K04380 MAPT, TAU; microtubule-associated protein tau
K04381 STMN1; stathmin 1
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04391 CD14; monocyte differentiation antigen CD14
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02308 DAXX; death-associated protein 6
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
K04406 MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K04408 MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K04411 STK4, MST1; serine/threonine kinase 4
K04412 STK3, MST2; serine/threonine kinase 3
K04414 MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K17534 MLK4, KIAA1804; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04423 MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K04424 ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04425 MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04434 MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
K04435 MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
K04436 MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
K04437 FLNA; filamin-A
K04438 CRK, CRKII; C-crk adapter molecule crk
K04439 ARRB; beta-arrestin
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04442 MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04451 TP53, P53; tumor protein p53
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K04453 MAX; Max protein
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K04455 HSPB1; heat shock protein beta-1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04457 PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
K04458 PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
K18018 PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
K18019 PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K18498 DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K17614 DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
K04460 PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
K04461 PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04014 Ras signaling pathway [PATH:ko04014]
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K08052 NF1; neurofibromin 1
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K12380 RASA3; Ras GTPase-activating protein 3
K17630 RASA4, CAPRI; Ras GTPase-activating protein 4
K17631 SYNGAP, RASA5; Ras/Rap GTPase-activating protein SynGAP
K17632 RASAL1; RAS protein activator-like 1
K17633 RASAL2; RAS protein activator-like 2
K17634 RASAL3; RAS protein activator-like 3
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K12358 FOXO4; forkhead box protein O4
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K25768 RALGAPA; Ral GTPase-activating protein subunit alpha
K25769 RALGAPB; Ral GTPase-activating protein subunit beta
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K17635 RGL1, RGL; ral guanine nucleotide dissociation stimulator-like 1
K17636 RGL2; ral guanine nucleotide dissociation stimulator-like 2
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K17637 EXOC2, SEC5; exocyst complex component 2
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09254 REL; c-Rel proto-oncogene protein
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K05702 AF6, MLLT4; afadin
K19613 SHOC2, SUR8; leucine-rich repeat protein SHOC2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K13618 PLA1A; phosphatidylserine sn-1 acylhydrolase [EC:3.1.1.111]
K01047 PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K04375 ELK1; ETS domain-containing protein Elk-1
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K17638 RIN1; Ras and Rab interactor 1
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07941 ARF6; ADP-ribosylation factor 6
|
04015 Rap1 signaling pathway [PATH:ko04015]
|
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07831 MRAS; Ras-related protein M-Ras
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K17697 DOCK4; dedicator of cytokinesis protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04270 P2RY1; P2Y purinoceptor 1
K04172 FPR1; formyl peptide receptor 1
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04266 ADORA2A, ADOR; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04438 CRK, CRKII; C-crk adapter molecule crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K06112 MAGI3; membrane-associated guanylate kinase-related
K08018 RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
K08020 RAPGEF6, PDZGEF2; Rap guanine nucleotide exchange factor 6
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07362 LAT; linker for activation of T cells family member 1
K17698 FYB, ADAP; FYN binding protein
K07361 LCP2; lymphocyte cytosolic protein 2
K17699 SKAP1, SKAP55; src kinase associated phosphoprotein 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K04145 DRD2; dopamine receptor D2
K04277 CNR1; cannabinoid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K17700 RAP1GAP, RAPGAP; RAP1 GTPase activating protein 1
K17701 SIPA1L1, E6TP1; signal-induced proliferation-associated 1 like protein 1
K08013 SIPA1; signal-induced proliferation-associated gene 1
K17702 SIPA1L2, SPAL2; signal-induced proliferation-associated 1 like protein 2
K17703 SIPA1L3, SPAL3; signal-induced proliferation-associated 1 like protein 3
K04680 ID1; DNA-binding protein inhibitor ID1
K16857 THBS1; thrombospondin 1
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K17704 APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
K06271 TLN; talin
K06476 ITGA2B, CD41; integrin alpha 2B
K06493 ITGB3, CD61; integrin beta 3
K05759 PFN; profilin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05746 ENAH, MENA; enabled
K23487 EVL; Ena/VASP-like protein
K05692 ACTB_G1; actin beta/gamma 1
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06082 FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2
K04393 CDC42; cell division control protein 42
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K05702 AF6, MLLT4; afadin
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K17705 KRIT1, CCM1; Krev interaction trapped protein 1
K17706 RGS14; regulator of G-protein signaling 14
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K05718 ITGAL, CD11a; integrin alpha L
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K05719 ITGB1, CD29; integrin beta 1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
|
04310 Wnt signaling pathway [PATH:ko04310]
|
K00181 PORCN; O-palmitoleoyl transferase [EC:2.3.1.250]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K01645 CER1; cerberus 1
K19882 NOTUM; O-palmitoleoyl-L-serine hydrolase [EC:3.1.1.98]
K01691 WIF1; WNT inhibitory factor 1
K16834 SOST; sclerostin
K02165 DKK1_2_4; dickkopf 1/2/4
K19614 SERPINF1, PEDF; pigment epithelium-derived factor
K02166 SFRP1; secreted frizzled-related protein 1
K02176 SFRP2; secreted frizzled-related protein 2
K25481 FRZB, SFRP3; secreted frizzled-related protein 3
K02185 SFRP4; secreted frizzled-related protein 4
K02222 SFRP5; secreted frizzled-related protein 5
K02306 DALLY; dally
K19471 RSPO1; R-spondin 1
K23097 RSPO2; R-spondin 2
K23098 RSPO3; R-spondin 3
K23099 RSPO4; R-spondin 4
K04309 LGR4, GPR48; leucine-rich repeat-containing G protein-coupled receptor 4
K04308 LGR5, GPR49; leucine-rich repeat-containing G protein-coupled receptor 5
K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K10162 BAMBI; BMP and activin membrane-bound inhibitor
K25812 APCDD1; protein APCDD1
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K25811 CCDC88C; protein Daple
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K03213 NKD; naked cuticle
K03344 IDAX; Dvl-binding protein IDAX
K03345 SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K26471 LZTS2; leucine zipper putative tumor suppressor 2
K04493 ICAT, CTNNBIP1; beta-catenin-interacting protein 1 (inhibitor of beta-catenin and Tcf-4)
K23402 CBY1; protein chibby 1
K04494 CHD8, HELSNF1; chromodomain helicase DNA binding protein 8 [EC:5.6.2.-]
K26734 MCC; colorectal mutant cancer protein
K25816 CCAR2, DBC1; cell cycle and apoptosis regulator protein 2
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K04495 SOX17; transcription factor SOX17 (SOX group F)
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04497 GRO, TLE; groucho
K23491 CTNND2; catenin delta-2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04499 RUVBL1, RVB1, INO80H; RuvB-like protein 1 [EC:5.6.2.4]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K04448 JUN; transcription factor AP-1
K04502 FOSL1; fos-like antigen 1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K22471 CCN4, WISP1; CCN family member 4
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04451 TP53, P53; tumor protein p53
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K04507 CACYBP, SIP; calcyclin binding protein
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K04508 TBL1; transducin (beta)-like 1
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K08110 GPC4; glypican 4
K05122 ROR1, NTRKR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
K05123 ROR2, NTRKR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K04510 VANGL; vang-like
K04511 PRICKLE; prickle
K19626 INVS; inversin
K04512 DAAM; dishevelled associated activator of morphogenesis
K04513 RHOA; Ras homolog gene family, member A
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
|
04330 Notch signaling pathway [PATH:ko04330]
|
04340 Hedgehog signaling pathway [PATH:ko04340]
|
04341 Hedgehog signaling pathway - fly [PATH:ko04341]
|
04350 TGF-beta signaling pathway [PATH:ko04350]
|
04390 Hippo signaling pathway [PATH:ko04390]
|
04391 Hippo signaling pathway - fly [PATH:ko04391]
|
04392 Hippo signaling pathway - multiple species [PATH:ko04392]
|
04370 VEGF signaling pathway [PATH:ko04370]
|
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K08273 SH2D2A, VRAP; SH2 domain-containing protein 2A
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K17447 SHC2; SHC-transforming protein 2
K05760 PXN; paxillin
K04393 CDC42; cell division control protein 42
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04455 HSPB1; heat shock protein beta-1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
|
04371 Apelin signaling pathway [PATH:ko04371]
|
04630 JAK-STAT signaling pathway [PATH:ko04630]
|
04064 NF-kappa B signaling pathway [PATH:ko04064]
|
04668 TNF signaling pathway [PATH:ko04668]
|
04066 HIF-1 signaling pathway [PATH:ko04066]
|
04068 FoxO signaling pathway [PATH:ko04068]
|
04020 Calcium signaling pathway [PATH:ko04020]
|
04070 Phosphatidylinositol signaling system [PATH:ko04070]
|
04072 Phospholipase D signaling pathway [PATH:ko04072]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K26384 SPTSS; serine palmitoyltransferase small subunit
K04710 CERS1, LASS1; sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K24621 CERS2_4, LASS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24622 CERS3, LASS3; very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K23727 CERS5_6, LASS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K12350 SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K18953 NSMAF, FAN; factor associated with neutral sphingomyelinase activation
K12351 SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K12349 ASAH2; neutral ceramidase [EC:3.5.1.23]
K01441 ACER1_2, ASAH3; alkaline ceramidase [EC:3.5.1.23]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04451 TP53, P53; tumor protein p53
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K03898 KNG, BK; kininogen
K04265 ADORA1; adenosine receptor A1
K04268 ADORA3; adenosine receptor A3
K03916 BDKRB2; bradykinin receptor B2
K04213 OPRD1; delta-type opioid receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04716 SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
K04717 SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K01634 SGPL1, DPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
K04288 S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
K04292 S1PR2, EDG5; sphingosine 1-phosphate receptor 2
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04290 S1PR3, EDG3; sphingosine 1-phosphate receptor 3
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04293 S1PR4, EDG6; sphingosine 1-phosphate receptor 4
K04295 S1PR5, EDG8; sphingosine 1-phosphate receptor 5
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
|
04024 cAMP signaling pathway [PATH:ko04024]
|
K05264 VIP; vasoactive intestinal peptide
K05256 CRH; corticotropin-releasing hormone
K08522 CGA; glycoprotein hormones alpha chain
K08521 LHB; lutropin subunit beta
K25483 GPHA2; glycoprotein hormone alpha-2
K25484 GPHB5; glycoprotein hormone beta-5
K05251 TSHB; thyrotropin subunit beta
K05228 POMC; proopiomelanocortin
K05259 GCG; glucagon
K05258 GIP; gastric inhibitory polypeptide
K05250 FSHB; follitropin subunit beta
K12334 NPPA; natriuretic peptide A
K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04144 DRD1; dopamine receptor D1
K05840 DRD5; dopamine receptor D5
K04266 ADORA2A, ADOR; adenosine receptor A2a
K04160 HTR4; 5-hydroxytryptamine receptor 4
K04162 HTR6; 5-hydroxytryptamine receptor 6
K04259 PTGER2; prostaglandin E receptor 2
K04587 ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
K04590 VIPR2; vasoactive intestinal peptide receptor 2
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04579 CRHR2; corticotropin releasing hormone receptor 2
K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
K04249 TSHR; thyrotropin receptor
K04200 MC2R; melanocortin 2 receptor
K04581 GLP1R; glucagon-like peptide 1 receptor
K04580 GIPR; gastric inhibitory polypeptide receptor
K08424 GPR119; glucose-dependent insulinotropic receptor
K04247 FSHR; follicle stimulating hormone receptor
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K05237 SST; somatostatin
K05232 NPY; neuropeptide Y
K05254 GHRL; ghrelin
K05243 OXT; oxytocin-neurophysin 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04145 DRD2; dopamine receptor D2
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04265 ADORA1; adenosine receptor A1
K04197 EDNRA; endothelin receptor type A
K04204 NPY1R; neuropeptide Y receptor type 1
K04217 SSTR1; somatostatin receptor 1
K04218 SSTR2; somatostatin receptor 2
K04221 SSTR5; somatostatin receptor 5
K08401 HCAR1, GPR81; hydroxycarboxylic acid receptor 1
K08402 HCAR2_3, GPR109; hydroxycarboxylic acid receptor 2/3
K04328 FFAR2, GPR43; free fatty acid receptor 2
K10042 SUCNR1, GPR91; succinate receptor 1
K04260 PTGER3; prostaglandin E receptor 3
K04229 OXTR; oxytocin receptor
K04284 GHSR; growth hormone secretagogue receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04948 CNGA1; cyclic nucleotide gated channel alpha 1
K04949 CNGA2; cyclic nucleotide gated channel alpha 2
K04950 CNGA3; cyclic nucleotide gated channel alpha 3
K04951 CNGA4; cyclic nucleotide gated channel alpha 4
K04952 CNGB1; cyclic nucleotide gated channel beta 1
K04953 CNGB3; cyclic nucleotide gated channel beta 3
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K21108 BVES, POPDC1; blood vessel epicardial substance
K26206 POPDC2; popeye domain-containing protein 2
K26207 POPDC3; popeye domain-containing protein 3
K04913 KCNK2, K2P2.1; potassium channel subfamily K member 2
K04955 HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2
K04957 HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4
K05673 ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05702 AF6, MLLT4; afadin
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K15494 PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04355 BDNF; brain-derived neurotrophic factor
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K06230 GLI3; zinc finger protein GLI3
K16797 GLI1; zinc finger protein GLI1
K06225 PTCH1; patched 1
K06231 HHIP; hedgehog interacting protein
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K18435 SOX9; transcription factor SOX9 (SOX group E)
K04665 AMH; anti-mullerian hormone
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K00232 E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K02158 BAD; Bcl-2-antagonist of cell death
K07188 LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12755 MYL9; myosin regulatory light chain 9
K12044 TNNI3; troponin I, cardiac muscle
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04962 RYR2; ryanodine receptor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K05031 CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K13360 FXYD1, PLM; FXYD domain-containing ion transport regulator 1
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K16056 ORAI1; calcium release-activated calcium channel protein 1
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
|
09143 Cell growth and death
|
|
09144 Cellular community - eukaryotes
|
04510 Focal adhesion [PATH:ko04510]
|
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K26256 EMP2; epithelial membrane protein 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K26255 EMP1; epithelial membrane protein 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K05692 ACTB_G1; actin beta/gamma 1
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K05699 ACTN1_4; actinin alpha 1/4
K06271 TLN; talin
K04437 FLNA; filamin-A
K27392 FLNB; filamin-B
K05760 PXN; paxillin
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06273 ZYX; zyxin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05700 VCL; vinculin
K06275 PARV; parvin
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
|
04520 Adherens junction [PATH:ko04520]
|
K06081 NECTIN1, PVRL1, CD111; poliovirus receptor-related protein 1
K06531 PVRL2, CD112; poliovirus receptor-related protein 2
K06592 PVRL3, CD113; poliovirus receptor-related protein 3
K06593 PVRL4; poliovirus receptor-related 4
K04237 PARD3; partitioning defective protein 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06082 FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05747 WAS; Wiskott-Aldrich syndrome protein
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K06083 WASF3; WAS protein family, member 3
K05702 AF6, MLLT4; afadin
K06084 LMO7, FBXO20; F-box protein 20
K06085 SSX2IP, ADIP; synovial sarcoma, X breakpoint 2 interacting protein
K06086 SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing protein 1
K05699 ACTN1_4; actinin alpha 1/4
K05700 VCL; vinculin
K05701 TJP1, ZO1; tight junction protein 1
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05692 ACTB_G1; actin beta/gamma 1
K04513 RHOA; Ras homolog gene family, member A
K14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]
K05693 PTPRM; receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48]
K05694 PTPRB, PTPB; receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K05696 PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K05698 PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K08889 FER, TYK3; tyrosine-protein kinase Fer [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05705 YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05706 SNAI2, SLUG; snail 2
K05707 SNAI1; snail 1
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K24472 HEG; protein HEG
K17705 KRIT1, CCM1; Krev interaction trapped protein 1
K26416 CCM2; cerebral cavernous malformations 2
K18269 PDCD10, CCM3; programmed cell death protein 10
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K26417 RASIP1; Ras-interacting protein 1
K26418 RADIL; Ras-associating and dilute domain-containing protein
K20644 ARHGAP29; Rho GTPase-activating protein 29
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
|
04530 Tight junction [PATH:ko04530]
|
04540 Gap junction [PATH:ko04540]
|
04550 Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
02030 Bacterial chemotaxis [PATH:ko02030]
|
02040 Flagellar assembly [PATH:ko02040]
|
04814 Motor proteins [PATH:ko04814]
|
04820 Cytoskeleton in muscle cells [PATH:ko04820]
|
04810 Regulation of actin cytoskeleton [PATH:ko04810]
|
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05717 FN1; fibronectin 1
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05718 ITGAL, CD11a; integrin alpha L
K06461 ITGAM, CD11b; integrin alpha M
K06462 ITGAX, CD11c; integrin alpha X
K06594 ITGAD, CD11d; integrin alpha D
K06524 ITGAE, CD103; integrin alpha E
K05719 ITGB1, CD29; integrin beta 1
K06464 ITGB2, CD18; integrin beta 2
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K03898 KNG, BK; kininogen
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04132 CHRM4; muscarinic acetylcholine receptor M4
K04133 CHRM5; muscarinic acetylcholine receptor M5
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K05720 FGD1; FYVE, RhoGEF and PH domain containing 1
K05722 FGD3; FYVE, RhoGEF and PH domain containing 3
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K05729 ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K26108 RGCC, RGC32; regulator of cell cycle RGCC
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K04513 RHOA; Ras homolog gene family, member A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13710 ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K10352 MYH9s; myosin heavy chain 9/10/11/14
K05740 DIAPH1; diaphanous 1
K05741 DIAPH2; diaphanous 2
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K00921 PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05745 DIAPH3, DRF3; diaphanous 3
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05746 ENAH, MENA; enabled
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05748 WASF2; WAS protein family, member 2
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05751 ABI2; abl interactor 2
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K05753 WASF1; WAS protein family, member 1
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05759 PFN; profilin
K05760 PXN; paxillin
K08007 EZR, VIL2; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K05764 TMSB4; thymosin, beta 4
K05765 CFL; cofilin
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05700 VCL; vinculin
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
K05768 GSN; gelsolin
K05699 ACTN1_4; actinin alpha 1/4
K02085 APC; adenomatosis polyposis coli protein
K05769 ARHGEF4_29, ASEF1_2; Rho guanine nucleotide exchange factor 4/29
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
|
04610 Complement and coagulation cascades [PATH:ko04610]
|
04611 Platelet activation [PATH:ko04611]
|
04613 Neutrophil extracellular trap formation [PATH:ko04613]
|
K06005 SAP; candidapepsin [EC:3.4.23.24]
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06740 SIGLEC9, CD329; sialic acid binding Ig-like lectin 9
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K05404 TLR7; toll-like receptor 7
K10170 TLR8, CD288; toll-like receptor 8
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K05692 ACTB_G1; actin beta/gamma 1
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K24669 PADI4, PAD4; protein-arginine deiminase 4 [EC:3.5.3.15]
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K05718 ITGAL, CD11a; integrin alpha L
K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
K04172 FPR1; formyl peptide receptor 1
K04173 FPRL; formyl peptide receptor-like
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03990 C3; complement component 3
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K03994 C5; complement component 5
K04010 C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
K10802 HMGB1; high mobility group protein B1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K06476 ITGA2B, CD41; integrin alpha 2B
K06493 ITGB3, CD61; integrin beta 3
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K06261 GP1BA, CD42b; platelet glycoprotein Ib alpha chain
K03900 VWF; von Willebrand factor
K06496 SELP, CD62P; selectin, platelet
K06544 SELPLG, CD162; selectin P ligand
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K20917 GSDMD; gasdermin-D
K11303 HAT1, KAT1; histone acetyltransferase 1 [EC:2.3.1.48]
K11251 H2A; histone H2A
K11252 H2B; histone H2B
K11254 H4; histone H4
K11253 H3; histone H3
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
K24665 AZU1; azurocidin
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
K05012 CLCN3_4_5; chloride channel 3/4/5
K09877 AQP9; aquaporin-9
|
04620 Toll-like receptor signaling pathway [PATH:ko04620]
|
04624 Toll and Imd signaling pathway [PATH:ko04624]
|
04621 NOD-like receptor signaling pathway [PATH:ko04621]
|
04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
|
04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
04625 C-type lectin receptor signaling pathway [PATH:ko04625]
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
K06751 MHC1; MHC class I antigen
K07980 KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
K07981 KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
K24232 KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
K06541 KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06523 ICAM2, CD102; intercellular adhesion molecule 2
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K07982 KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
K24233 KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
K06742 NCR2, CD336; natural cytotoxicity triggering receptor 2
K07992 TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K19251 HA; Influenza A virus hemagglutinin
K06856 IGH; immunoglobulin heavy chain
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K06741 NCR1, CD335; natural cytotoxicity triggering receptor 1
K06743 NCR3, CD337; natural cytotoxicity triggering receptor 3
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K26356 LAT2, LAB; linker for activation of T-cells family member 2
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07984 SH3BP2; SH3-domain binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07985 MIC; MHC class I-related protein
K07986 ULBP; UL16 binding protein
K06728 KLRK1, CD314; killer cell lectin-like receptor subfamily K member 1
K07988 HCST, DAP10; hematopoietic cell signal transducer
K06479 CD48, BCM1; CD48 antigen
K06582 CD244; natural killer cell receptor 2B4
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K07989 SH2D1B, EAT2; SH2 domain-containing protein 1B
K07990 SH2D1A, SAP; SH2 domain-containing protein 1A
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07818 PRF1; perforin 1
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K24207 KLRA1, Ly49A; killer cell lectin-like receptor subfamily A member 1
K24208 KLRA3, Ly49C; killer cell lectin-like receptor subfamily A member 3
K24238 KLRA7, Ly49G2; killer cell lectin-like receptor subfamily A member 7
K24240 KLRA9, Ly49I; killer cell lectin-like receptor subfamily A member 9
K23459 KLRA4, LY49D; killer cell lectin-like receptor subfamily A member 4
K24239 KLRA8, Ly49H; killer cell lectin-like receptor subfamily A member 8
K07987 RAET1; retinoic acid early transcript 1
|
04612 Antigen processing and presentation [PATH:ko04612]
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
04658 Th1 and Th2 cell differentiation [PATH:ko04658]
|
04659 Th17 cell differentiation [PATH:ko04659]
|
04657 IL-17 signaling pathway [PATH:ko04657]
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
K06856 IGH; immunoglobulin heavy chain
K06506 CD79A, IGA; CD79A antigen
K06507 CD79B, IGB; CD79B antigen
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K12229 DAPP1, BAM32; dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
K07371 BLNK; B-cell linker protein
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K26239 BANK1; B-cell scaffold protein with ankyrin repeats
K08890 BLK; B lymphoid tyrosine kinase [EC:2.7.10.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K12362 RASGRP3; RAS guanyl-releasing protein 3
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K07367 CARD11; caspase recruitment domain-containing protein 11
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K19831 IFITM1, CD225; interferon induced transmembrane protein 1
K06508 CD81, TAPA1, TSPAN28; CD81 antigen
K06465 CD19; B-lymphocyte antigen CD19
K04012 CR2, CD21; complement receptor type 2
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909 SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K06512 LILR, CD85; leukocyte immunoglobulin-like receptor
K06467 CD22, SIGLEC2; CD22 antigen
K06504 CD72; CD72 antigen
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
K06856 IGH; immunoglobulin heavy chain
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05430 IL4; interleukin 4
K05435 IL13; interleukin 13
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K07362 LAT; linker for activation of T cells family member 1
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K20735 ALOX5AP, FLAP; arachidonate 5-lipoxygenase-activating protein
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K13536 MARCKSL1, MRP; MARCKS-related protein
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K05768 GSN; gelsolin
K05730 VAV; guanine nucleotide exchange factor VAV
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K06274 VASP; vasodilator-stimulated phosphoprotein
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K06083 WASF3; WAS protein family, member 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K04438 CRK, CRKII; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909 SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K08091 GAB2; GRB2-associated-binding protein 2
K07362 LAT; linker for activation of T cells family member 1
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K12562 AMPH; amphiphysin
K12559 MYO10; myosin X
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
K06785 JAM3; junctional adhesion molecule 3
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K06735 JAM2, CD322; junctional adhesion molecule 2
K06483 ITGA4, CD49d; integrin alpha 4
K05719 ITGB1, CD29; integrin beta 1
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K06520 CD99, MIC2; CD99 antigen
K05718 ITGAL, CD11a; integrin alpha L
K06089 F11R, JAM1, CD321; junctional adhesion molecule 1
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K06087 CLDN; claudin
K06088 OCLN; occludin
K06787 ESAM; endothelial cell adhesion molecule
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K08007 EZR, VIL2; ezrin
K05763 MSN; moesin
K05692 ACTB_G1; actin beta/gamma 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K02105 CTNNB1; catenin beta 1
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K05691 CTNNA; catenin alpha
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K06514 THY1, CD90; Thy-1 cell surface antigen
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K05702 AF6, MLLT4; afadin
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K08013 SIPA1; signal-induced proliferation-associated gene 1
K06274 VASP; vasodilator-stimulated phosphoprotein
K05699 ACTN1_4; actinin alpha 1/4
K05700 VCL; vinculin
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K08016 TXK, RLK; tyrosine-protein kinase TXK [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04393 CDC42; cell division control protein 42
K07873 RHOH, TTF; Ras homolog gene family, member H
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10029 PPBP, CXCL7; platelet basic protein
K10030 IL8, CXCL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10035 CXCL16; C-X-C motif chemokine 16
K10034 CXCL15; C-X-C motif chemokine 15
K05407 PF4, CXCL4; platelet factor 4
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05514 CCL1; C-C motif chemokine 1
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K21092 CCL14; C-C motif chemokine 14
K05511 CCL15_23; C-C motif chemokine 15/23
K21093 CCL16; C-C motif chemokine 16
K21083 CCL17; C-C motif chemokine 17
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21, SLC; C-C motif chemokine 21
K21095 CCL22; C-C motif chemokine 22
K21097 CCL24; C-C motif chemokine 24
K13072 CCL25; C-C motif chemokine 25
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04191 CXCR6, CD186; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04177 CCR2, CD192; C-C chemokine receptor type 2
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04185 CCR10; C-C chemokine receptor type 10
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11224 STAT5B; signal transducer and activator of transcription 5B
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K08891 FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K12367 DOCK2; dedicator of cytokinesis protein 2
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04237 PARD3; partitioning defective protein 3
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
|
|
09152 Endocrine system
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|
09153 Circulatory system
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
04320 Dorso-ventral axis formation [PATH:ko04320]
|
04360 Axon guidance [PATH:ko04360]
|
K07522 NTNG1; netrin-G1
K16359 NTNG2; netrin-G2
K07523 LRRC4C, NGL1; netrin-G1 ligand
K16351 LRRC4, NGL2; netrin-G2 ligand
K06843 NTN1; netrin 1
K06844 NTN3; netrin 3
K06845 NTN4; netrin 4
K06765 DCC; deleted in colorectal carcinoma
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04964 TRPC1; transient receptor potential cation channel subfamily C member 1
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K04967 TRPC4; transient receptor potential cation channel subfamily C member 4
K04968 TRPC5; transient receptor potential cation channel subfamily C member 5
K04969 TRPC6; transient receptor potential cation channel subfamily C member 6
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K07520 ABLIM; actin-binding LIM protein
K07365 NCK1; NCK adaptor protein 1
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K07521 UNC5; netrin receptor unc-5
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K23096 RGMA; repulsive guidance molecule A
K06766 NEO1; neogenin
K12753 MYL5; myosin regulatory light chain 5
K12755 MYL9; myosin regulatory light chain 9
K12757 MYL12; myosin regulatory light chain 12
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K24609 LRIG2; leucine-rich repeats and immunoglobulin-like domains protein 2
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05102 EPHA1, EPH; Eph receptor A1 [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05104 EPHA3, HEK, TYRO4; Eph receptor A3 [EC:2.7.10.1]
K05105 EPHA4, SEK, TYRO1; Eph receptor A4 [EC:2.7.10.1]
K05106 EPHA5, EHK1, TYRO4; Eph receptor A5 [EC:2.7.10.1]
K05107 EPHA6, EHK2; Eph receptor A6 [EC:2.7.10.1]
K05108 EPHA7, EHK3, HEK11; EphA7 [EC:2.7.10.1]
K05109 EPHA8, EEK; Eph receptor A8 [EC:2.7.10.1]
K05110 EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
K05111 EPHB2, ERK, DRT; Eph receptor B2 [EC:2.7.10.1]
K05112 EPHB3, HEK2, ETK2; Eph receptor B3 [EC:2.7.10.1]
K05113 EPHB4, HTK; Eph receptor B4 [EC:2.7.10.1]
K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K05746 ENAH, MENA; enabled
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K07525 NGEF, EPHEXIN, ARHGEF27; neuronal guanine nucleotide exchange factor
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K19862 NCK2, GRB4; NCK adaptor protein 2
K07524 RGS3; regulator of G-protein signalling 3
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K06753 ROBO1; roundabout, axon guidance receptor 1
K06754 ROBO2; roundabout, axon guidance receptor 2
K06755 ROBO3; roundabout, axon guidance receptor 3
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K06840 SEMA3; semaphorin 3
K06820 PLXNA; plexin A
K06724 NRP1, CD304; neuropilin 1
K06550 L1CAM, CD171; L1 cell adhesion molecule
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K07530 RHOD; Ras homolog gene family, member D
K07531 RND1; Rho family GTPase 1
K07527 FES, FPS; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
K07529 DPYSL5, CRAM; dihydropyrimidinase-like 5
K07528 DPYSL2, CRMP2; dihydropyrimidinase-like 2
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06521 SEMA4, CD100; semaphorin 4
K06841 SEMA5; semaphorin 5
K06842 SEMA6; semaphorin 6
K06821 PLXNB; plexin B
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07829 RRAS; Ras-related protein R-Ras
K06529 SEMA7, CD108; semaphorin 7
K06572 PLXNC, CD232; plexin C
K05719 ITGB1, CD29; integrin beta 1
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K20020 BOC; brother of CDO
K00444 WNT5; wingless-type MMTV integration site family, member 5
K02329 FZD3; frizzled 3
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04237 PARD3; partitioning defective protein 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06093 PARD6; partitioning defective protein 6
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K16621 BMP7; bone morphogenetic protein 7
K20013 GDF7; growth differentiation factor 7
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
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04361 Axon regeneration [PATH:ko04361]
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04380 Osteoclast differentiation [PATH:ko04380]
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|
09149 Aging
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|
09159 Environmental adaptation
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|
09160 Human Diseases
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|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG, BK; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05072 IL7R, CD127; interleukin 7 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1, pnt; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K08528 RARB, NR1B2; retinoic acid receptor beta
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP, PG; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
K04357 EGF; epidermal growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K05747 WAS; Wiskott-Aldrich syndrome protein
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K06083 WASF3; WAS protein family, member 3
K04684 SP1; transcription factor Sp1
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K14387 SLC5A7, CHT1; solute carrier family 5 (high affinity choline transporter), member 7
K06515 SLC44A1, CD92; solute carrier family 44 (choline transporter-like protein), member 1
K15377 SLC44A2_4_5; solute carrier family 44 (choline transporter-like protein), member 2/4/5
K15282 SLC44A3; solute carrier family 44 (choline transporter-like protein), member 3
K08198 SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
K08199 SLC22A2, OCT2; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
K08200 SLC22A3, OCT3; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3
K08202 SLC22A4_5, OCTN; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5
K14156 CHK; choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K00968 PCYT1; choline-phosphate cytidylyltransferase [EC:2.7.7.15]
K00994 CHPT1, CPT1; diacylglycerol cholinephosphotransferase [EC:2.7.8.2]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K00901 dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06128 LYPLA1; lysophospholipase I [EC:3.1.1.5]
K18695 GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:ko05210]
|
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS, KRAS2; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K10132 BBC3, PUMA; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
|
05212 Pancreatic cancer [PATH:ko05212]
|
K07827 KRAS, KRAS2; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05729 ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K05448 VEGFA; vascular endothelial growth factor A
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
|
05225 Hepatocellular carcinoma [PATH:ko05225]
|
05226 Gastric cancer [PATH:ko05226]
|
05214 Glioma [PATH:ko05214]
|
05216 Thyroid cancer [PATH:ko05216]
|
05221 Acute myeloid leukemia [PATH:ko05221]
|
05220 Chronic myeloid leukemia [PATH:ko05220]
|
05217 Basal cell carcinoma [PATH:ko05217]
|
05218 Melanoma [PATH:ko05218]
|
05211 Renal cell carcinoma [PATH:ko05211]
|
05219 Bladder cancer [PATH:ko05219]
|
05215 Prostate cancer [PATH:ko05215]
|
05213 Endometrial cancer [PATH:ko05213]
|
05224 Breast cancer [PATH:ko05224]
|
05222 Small cell lung cancer [PATH:ko05222]
|
05223 Non-small cell lung cancer [PATH:ko05223]
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
|
K24266 gp120; HIV envelope glycoprotein gp120
K06454 CD4; T-cell surface glycoprotein CD4
K22890 vpu; HIV-1 protein Vpu
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K22891 nef; HIV protein Nef
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05760 PXN; paxillin
K04438 CRK, CRKII; C-crk adapter molecule crk
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K02158 BAD; Bcl-2-antagonist of cell death
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K19258 tat; HIV protein Tat
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K22892 vif; HIV virion infectivity factor
K22202 vpr; HIV virus protein R
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]
K06731 BST2, CD317; bone marrow stromal cell antigen 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K12392 AP1B1; AP-1 complex subunit beta-1
K12391 AP1G1; AP-1 complex subunit gamma-1
K12393 AP1M; AP-1 complex subunit mu
K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
K12395 AP1S3; AP-1 complex subunit sigma-3
K08055 B2M; beta-2-microglobulin
K03873 ELOB, TCEB2; elongin-B
K03872 ELOC, TCEB1; elongin-C
K10612 CUL5; cullin 5
K10611 RBX2, ROC2, RNF7; RING-box protein 2
K11789 DCAF1, VPRBP; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
K10610 DDB1; DNA damage-binding protein 1
K10609 CUL4; cullin 4
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
|
05161 Hepatitis B [PATH:ko05161]
|
05160 Hepatitis C [PATH:ko05160]
|
05171 Coronavirus disease - COVID-19 [PATH:ko05171]
|
05164 Influenza A [PATH:ko05164]
|
05162 Measles [PATH:ko05162]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K22774 UL123; HCMV immediate-early protein 1
K22775 UL122; Cytomegalovirus viral transcription factor IE2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K22776 UL38; Cytomegalovirus apoptosis inhibitor UL38
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04684 SP1; transcription factor Sp1
K22777 gH, UL75; Cytomegalovirus envelope glycoprotein H
K22778 gL, UL115; Cytomegalovirus envelope glycoprotein L
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K22779 UL82; Cytomegalovirus tegument protein pp71
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K22780 UL26; Cytomegalovirus tegument protein UL26
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K10030 IL8, CXCL8; interleukin 8
K05405 IL6; interleukin 6
K22781 US28; HCMV envelope protein US28
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K16529 ARHGEF13; A-kinase anchor protein 13
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K02105 CTNNB1; catenin beta 1
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05448 VEGFA; vascular endothelial growth factor A
K22782 UL33; Cytomegalovirus G-protein coupled receptor UL33
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K22783 US27; HCMV envelope glycoprotein US27
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K05760 PXN; paxillin
K21533 vIL10; Herpesviridae/Poxviridae viral interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K21046 UL146; HCMV chemokine vCXCL1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K22784 UL22A; HCMV glycoprotein UL22A
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K22785 US6; HCMV membrane glycoprotein US6
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K21050 US2; HCMV unique short US2 glycoprotein
K22786 US11; HCMV membrane glycoprotein US11
K22787 US3; HCMV membrane glycoprotein US3
K21051 US10; HCMV unique short US10 glycoprotein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K22788 UL36; Cytomegalovirus viral inhibitor of caspase-8-induced apoptosis
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K22789 UL37; UL37 HCMV immediate early glycoprotein
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05165 Human papillomavirus infection [PATH:ko05165]
|
|
09171 Infectious disease: bacterial
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
05132 Salmonella infection [PATH:ko05132]
|
05131 Shigellosis [PATH:ko05131]
|
05135 Yersinia infection [PATH:ko05135]
|
K13735 yeeJ; adhesin/invasin
K12341 yadA; adhesin YadA
K05717 FN1; fibronectin 1
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K05719 ITGB1, CD29; integrin beta 1
K07863 RHOG; Ras homolog gene family, member G
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K06856 IGH; immunoglobulin heavy chain
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K19475 WIPF; WAS/WASL-interacting protein
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05748 WASF2; WAS protein family, member 2
K05760 PXN; paxillin
K12487 GIT2; G protein-coupled receptor kinase interactor 2
K13710 ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K21072 ARHGEF28; A-kinase anchor protein 28
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K17698 FYB, ADAP; FYN binding protein
K23471 SKAP2; src kinase-associated phosphoprotein 2
K23472 ypkA, yopO; serine/threonine protein kinase YpkA [EC:2.7.11.1]
K08599 yopT; YopT peptidase [EC:3.4.22.-]
K23473 yopE; outer membrane virulence protein YopE
K23474 yopH; tyrosine-protein phosphatase YopH [EC:3.1.3.48]
K23475 yopB, popB, aopB; transloator
K23476 yopD, popD, aopD; transloator
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K12803 MEFV; pyrin
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18, IL1F4; interleukin 18
K04519 IL1B; interleukin 1 beta
K23477 yopQ, yopK; protein YopQ
K23478 yopM; outer membrane protein YopM
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05842 TRIF; toll-like receptor adapter molecule 1
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K05415 IFNB; interferon beta
K08598 yopJ; YopJ protease family
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K14624 CCL2, MCP1; C-C motif chemokine 2
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05429 IL2; interleukin 2
K05443 IL10, CSIF; interleukin 10
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
|
09174 Infectious disease: parasitic
|
|
09163 Immune disease
|
|
09164 Neurodegenerative disease
|
05010 Alzheimer disease [PATH:ko05010]
|
05012 Parkinson disease [PATH:ko05012]
|
05014 Amyotrophic lateral sclerosis [PATH:ko05014]
|
05016 Huntington disease [PATH:ko05016]
|
05017 Spinocerebellar ataxia [PATH:ko05017]
|
05020 Prion disease [PATH:ko05020]
|
K05634 PRNP, PrP, CD230; prion protein
K06491 NCAM, CD56; neural cell adhesion molecule
K05635 LAMC1; laminin, gamma 1
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K09553 STIP1; stress-induced-phosphoprotein 1
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02159 BAX; apoptosis regulator BAX
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K20858 MCU; calcium uniporter protein, mitochondrial
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K02599 NOTCH1; Notch 1
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K09203 EGR1; early growth response protein 1
K12499 CCL5; C-C motif chemokine 5
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
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05022 Pathways of neurodegeneration - multiple diseases [PATH:ko05022]
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09165 Substance dependence
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09166 Cardiovascular disease
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05417 Lipid and atherosclerosis [PATH:ko05417]
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05418 Fluid shear stress and atherosclerosis [PATH:ko05418]
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K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K02183 CALM; calmodulin
K08107 GPC1; glypican 1
K06257 SDC1, CD138; syndecan 1
K16336 SDC2, CD362; syndecan 2
K16338 SDC4; syndecan 4
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K14381 SQSTM1; sequestosome 1
K03671 TXN, trxA; thioredoxin
K12336 NPPC; natriuretic peptide C
K01940 argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]
K03907 THBD, CD141; thrombomodulin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K02105 CTNNB1; catenin beta 1
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K17845 KLF2; krueppel-like factor 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K12791 ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
K04513 RHOA; Ras homolog gene family, member A
K05692 ACTB_G1; actin beta/gamma 1
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K16864 MIR10A; microRNA 10a
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K20607 MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K14624 CCL2, MCP1; C-C motif chemokine 2
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K16366 EDN1; endothelin-1
K05448 VEGFA; vascular endothelial growth factor A
K04662 BMP4; bone morphogenetic protein 4
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K08008 NOX1, MOX1; NADPH oxidase 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K12160 SUMO, SMT3; small ubiquitin-related modifier
K02161 BCL2; apoptosis regulator Bcl-2
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05410 Hypertrophic cardiomyopathy [PATH:ko05410]
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05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:ko05412]
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05414 Dilated cardiomyopathy [PATH:ko05414]
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05415 Diabetic cardiomyopathy [PATH:ko05415]
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K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07191 SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K12044 TNNI3; troponin I, cardiac muscle
K04962 RYR2; ryanodine receptor 2
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04684 SP1; transcription factor Sp1
K09821 AGT, SERPINA8; angiotensinogen
K01380 REN; renin [EC:3.4.23.15]
K01329 CMA1; chymase [EC:3.4.21.39]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04166 AGTR1; angiotensin II receptor type 1
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K06259 CD36; CD36 antigen
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K17605 PPP2R4, PTPA; serine/threonine-protein phosphatase 2A activator
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K08766 CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K17902 TBC1D4, AS160; TBC1 domain family member 4
K22138 MPC1; mitochondrial pyruvate carrier 1
K22139 MPC2; mitochondrial pyruvate carrier 2
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K00036 G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00383 GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
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05416 Viral myocarditis [PATH:ko05416]
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K06788 CXADR, CAR; coxsackievirus and adenovirus receptor
K04006 DAF, CD55; decay accelerating factor
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06278 CAV1; caveolin 1
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K22194 SSPN; sarcospan
K12565 SGCA; alpha-sarcoglycan
K12566 SGCB; beta-sarcoglycan
K12564 SGCG; gamma-sarcoglycan
K12563 SGCD; delta-sarcoglycan
K27061 SGCE; epsilon-sarcoglycan
K27062 SGCZ; zeta-sarcoglycan
K05637 LAMA1_2; laminin, alpha 1/2
K06265 DAG1; dystroglycan 1
K12959 CAV3; caveolin 3
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K24063 SNTA; alpha-syntrophin
K24064 SNTB; beta-syntrophin
K26998 DTNA; dystrobrevin alpha
K10366 DMD; dystrophin
K05692 ACTB_G1; actin beta/gamma 1
K03260 EIF4G; translation initiation factor 4G
K04503 CCND1; G1/S-specific cyclin-D1
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K17751 MYH6_7; myosin heavy chain 6/7
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06751 MHC1; MHC class I antigen
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K07818 PRF1; perforin 1
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06856 IGH; immunoglobulin heavy chain
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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09182 Protein families: genetic information processing
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09183 Protein families: signaling and cellular processes
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02000 Transporters [BR:ko02000]
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02044 Secretion system [BR:ko02044]
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02042 Bacterial toxins [BR:ko02042]
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02022 Two-component system [BR:ko02022]
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02035 Bacterial motility proteins [BR:ko02035]
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03037 Cilium and associated proteins [BR:ko03037]
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04812 Cytoskeleton proteins [BR:ko04812]
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04147 Exosome [BR:ko04147]
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02048 Prokaryotic defense system [BR:ko02048]
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04030 G protein-coupled receptors [BR:ko04030]
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04050 Cytokine receptors [BR:ko04050]
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04054 Pattern recognition receptors [BR:ko04054]
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03310 Nuclear receptors [BR:ko03310]
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04040 Ion channels [BR:ko04040]
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04031 GTP-binding proteins [BR:ko04031]
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K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04631 GNAT1_2; guanine nucleotide-binding protein G(t) subunit alpha 1/2
K19729 GNAT3; guanine nucleotide-binding protein G(t) subunit alpha 3
K04535 GNAZ; guanine nucleotide-binding protein G(z) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K19860 GPA1; guanine nucleotide-binding protein alpha-1 subunit
K04640 GNA; guanine nucleotide-binding protein subunit alpha, other
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07972 GNB; guanine nucleotide-binding protein subunit beta, other
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K24772 GG1_2; guanine nucleotide-binding protein subunit gamma 1/2, plant
K24773 GG3; guanine nucleotide-binding protein subunit gamma 3, plant
K07973 GNG; guanine nucleotide-binding protein subunit gamma, fungi
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K17196 ERAS; GTPase Eras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K07832 RIT1; Ras-like without CAAX 1
K07833 RIT2, RIN; Ras-like without CAAX 2
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07837 RAP2A; Ras-related protein Rap-2A
K07838 RAP2B; Ras-related protein Rap-2B
K07839 RAP2C; Ras-related protein Rap-2C
K07840 DIRAS1; DIRAS family, GTP-binding Ras-like 1
K07841 DIRAS2; DIRAS family, GTP-binding Ras-like 2
K07842 DIRAS3, NOEY2; DIRAS family, GTP-binding Ras-like 3
K07843 RASD1; RAS, dexamethasone-induced Ras-related protein 1
K07844 RASD2; RASD family, member 2
K07845 RRAD, RAD1; Ras-related associated with diabetes
K07846 GEM; GTP binding protein overexpressed in skeletal muscle
K07847 REM1; Rad and Gem related GTP binding protein 1
K07848 REM2; Rad and Gem related GTP binding protein 2
K07208 RHEB; Ras homolog enriched in brain
K07849 RHEBL1; Ras homolog enriched in brain like 1
K17197 NKIRAS; NF-kappa-B inhibitor-interacting Ras-like protein
K07850 RASL10A, RRP22; Ras-like protein family member 10A
K07851 RASL10B; Ras-like protein family member 10B
K07852 RASL11A; Ras-like protein family member 11A
K07853 RASL11B; Ras-like protein family member 11B
K07854 RASL12, RIS; Ras-like protein family member 12
K07855 RERG; Ras-related and estrogen-regulated growth inhibitor
K17198 RERGL; Ras-related and estrogen-regulated growth inhibitor-like protein
K04513 RHOA; Ras homolog gene family, member A
K07856 RHOB; Ras homolog gene family, member B
K07857 RHOC; Ras homolog gene family, member C
K07531 RND1; Rho family GTPase 1
K07858 RND2; Rho family GTPase 2
K07859 RND3; Rho family GTPase 3
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K07863 RHOG; Ras homolog gene family, member G
K04393 CDC42; cell division control protein 42
K07864 RHOJ, TCL; Ras homolog gene family, member J
K07194 RHOQ, TC10; Ras homolog gene family, member Q
K07873 RHOH, TTF; Ras homolog gene family, member H
K07865 RHOU, WRCH1; Ras homolog gene family, member U
K07866 RHOV, WRCH2; Ras homolog gene family, member V
K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
K07870 RHOT1, ARHT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
K07871 RHOT2, ARHT2; mitochondrial Rho GTPase 2 [EC:3.6.5.-]
K07530 RHOD; Ras homolog gene family, member D
K07872 RHOF, RIF; Ras homolog gene family, member F
K07934 IFT27, RAYL, RABL4; intraflagellar transport protein 27
K07975 K07975; Rho family, other
K07874 RAB1A; Ras-related protein Rab-1A
K07875 RAB1B; Ras-related protein Rab-1B
K07876 RAB35, RAB1C; Ras-related protein Rab-35
K07877 RAB2A; Ras-related protein Rab-2A
K07878 RAB2B; Ras-related protein Rab-2B
K07879 RAB4A, RAB4; Ras-related protein Rab-4A
K07880 RAB4B; Ras-related protein Rab-4B
K07881 RAB14; Ras-related protein Rab-14
K07882 RAB3A; Ras-related protein Rab-3A
K06108 RAB3B; Ras-related protein Rab-3B
K07883 RAB3C; Ras-related protein Rab-3C
K07884 RAB3D; Ras-related protein Rab-3D
K07885 RAB27A; Ras-related protein Rab-27A
K07886 RAB27B; Ras-related protein Rab-27B
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07909 RAB17; Ras-related protein Rab-17
K07891 RAB22; Ras-related protein Rab-22
K07893 RAB6A; Ras-related protein Rab-6A
K07894 RAB6B; Ras-related protein Rab-6B
K07895 RAB6C; Ras-related protein Rab-6C
K07896 RAB41; Ras-related protein Rab-41
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K07899 RAB9A, RAB9; Ras-related protein Rab-9A
K07900 RAB9B; Ras-related protein Rab-9B
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07902 RAB8B; Ras-related protein Rab-8B
K07903 RAB10; Ras-related protein Rab-10
K06109 RAB13; Ras-related protein Rab-13
K07904 RAB11A; Ras-related protein Rab-11A
K07905 RAB11B; Ras-related protein Rab-11B
K07906 RAB25; Ras-related protein Rab-25
K07907 RAB12; Ras-related protein Rab-12
K07910 RAB18; Ras-related protein Rab-18
K07908 RAB15; Ras-related protein Rab-15
K17047 RAB19; Ras-related protein Rab-19
K07917 RAB30; Ras-related protein Rab-30
K07930 RAB43; Ras-related protein Rab-43
K07911 RAB20; Ras-related protein Rab-20
K07890 RAB21; Ras-related protein Rab-21
K07912 RAB24; Ras-related protein Rab-24
K06234 RAB23; Ras-related protein Rab-23
K07913 RAB26; Ras-related protein Rab-26
K07914 RAB37; Ras-related protein Rab-37
K07915 RAB28; Ras-related protein Rab-28
K07916 RAB7L1, RAB7L; Ras-related protein Rab-7L1
K07918 RAB32; Ras-related protein Rab-32
K07923 RAB38; Ras-related protein Rab-38
K07919 RAB33A; Ras-related protein Rab-33A
K07920 RAB33B; Ras-related protein Rab-33B
K07921 RAB34; Ras-related protein Rab-34
K07922 RAB36; Ras-related protein Rab-36
K07924 RAB39A; Ras-related protein Rab-39A
K07925 RAB39B; Ras-related protein Rab-39B
K07929 RAB42; Ras-related protein Rab-42
K07928 RAB40; Ras-related protein Rab-40
K17199 RASEF, RAB45; Ras and EF-hand domain-containing protein
K07931 RABL2; Rab-like protein 2
K07976 RAB; Rab family, other
K07936 RAN; GTP-binding nuclear protein Ran
K07937 ARF1_2; ADP-ribosylation factor 1/2
K07938 ARF3; ADP-ribosylation factor 3
K07939 ARF4; ADP-ribosylation factor 4
K07940 ARF5; ADP-ribosylation factor 5
K07941 ARF6; ADP-ribosylation factor 6
K07942 ARL1; ADP-ribosylation factor-like protein 1
K07949 ARL5A; ADP-ribosylation factor-like protein 5A
K07950 ARL5B; ADP-ribosylation factor-like protein 5B
K07943 ARL2; ADP-ribosylation factor-like protein 2
K07944 ARL3; ADP-ribosylation factor-like protein 3
K07945 ARL4; ADP-ribosylation factor-like protein 4
K07951 ARL6, BBS3; ADP-ribosylation factor-like protein 6
K07952 ARFRP1; ADP-ribosylation factor related protein 1
K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
K07955 ARL8; ADP-ribosylation factor-like protein 8
K07957 ARL9; ADP-ribosylation factor-like protein 9
K07958 ARL10; ADP-ribosylation factor-like protein 10
K07959 ARL11; ADP-ribosylation factor-like protein 11
K07960 ARL12; ADP-ribosylation factor-like protein 12
K07961 ARL13A; ADP-ribosylation factor-like protein 13A
K07962 ARL13B, ARL2L1; ADP-ribosylation factor-like protein 13B
K17200 ARL14, ARF7; ADP-ribosylation factor-like protein 14
K17201 ARL15; ADP-ribosylation factor-like protein 15
K07963 TRIM23, ARFD1; tripartite motif-containing protein 23 [EC:2.3.2.27]
K07933 RABL3; Rab-like protein 3
K07935 IFT22, RABL5; intraflagellar transport protein 22
K12272 SRPRB, SRP102; signal recognition particle receptor subunit beta
K24888 GTPBP2; GTP-binding protein 2
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04052 Cytokines and neuropeptides [BR:ko04052]
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04515 Cell adhesion molecules [BR:ko04515]
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04090 CD molecules [BR:ko04090]
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01504 Antimicrobial resistance genes [BR:ko01504]
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00535 Proteoglycans [BR:ko00535]
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00536 Glycosaminoglycan binding proteins [BR:ko00536]
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
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04091 Lectins [BR:ko04091]
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04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)