09100 Metabolism
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04014 Ras signaling pathway [PATH:ko04014]
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04015 Rap1 signaling pathway [PATH:ko04015]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04341 Hedgehog signaling pathway - fly [PATH:ko04341]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway - fly [PATH:ko04391]
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04392 Hippo signaling pathway - multiple species [PATH:ko04392]
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04370 VEGF signaling pathway [PATH:ko04370]
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04371 Apelin signaling pathway [PATH:ko04371]
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04630 JAK-STAT signaling pathway [PATH:ko04630]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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04668 TNF signaling pathway [PATH:ko04668]
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04066 HIF-1 signaling pathway [PATH:ko04066]
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04068 FoxO signaling pathway [PATH:ko04068]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04072 Phospholipase D signaling pathway [PATH:ko04072]
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04071 Sphingolipid signaling pathway [PATH:ko04071]
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04024 cAMP signaling pathway [PATH:ko04024]
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04022 cGMP-PKG signaling pathway [PATH:ko04022]
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04151 PI3K-Akt signaling pathway [PATH:ko04151]
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; B-lymphocyte antigen CD19
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 RXRA, NR2B1; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB, C-MYB; transcriptional activator Myb
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
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04152 AMPK signaling pathway [PATH:ko04152]
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04150 mTOR signaling pathway [PATH:ko04150]
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K13780 SLC7A5, LAT1; solute carrier family 7 (L-type amino acid transporter), member 5
K06519 SLC3A2, MDU1, CD98; solute carrier family 3, member 2
K14995 SLC38A9; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K20397 LAMTOR1; ragulator complex protein LAMTOR1
K20398 LAMTOR2; ragulator complex protein LAMTOR2
K04370 LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
K20399 LAMTOR4; ragulator complex protein LAMTOR4
K16344 LAMTOR5, HBXIP; ragulator complex protein LAMTOR5
K09594 FLCN, BHD; folliculin
K20400 FNIP1; folliculin-interacting protein 1
K20401 FNIP2; folliculin-interacting protein 2
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K20394 SESN2; sestrin 2
K23080 CASTOR1; cytosolic arginine sensor for mTORC1 subunit 1
K23081 CASTOR2; cytosolic arginine sensor for mTORC1 subunit 2
K20407 MIOS, MIO, SEA4; SEA/GATOR complex protein SEA4/MIOS
K14299 SEH1; nucleoporin SEH1
K20408 WDR24, SEA2; SEA/GATOR complex protein SEA2/WDR24
K20409 WDR59, SEA3; SEA/GATOR complex protein SEA3/WDR59
K14004 SEC13; protein transport protein SEC13
K20404 DEPDC5, SEA1; SEA/GATOR complex protein SEA1/DEPDC5
K20405 NPRL2, NPR2; nitrogen permease regulator 2
K20406 NPRL3, NPR3; nitrogen permease regulator 3
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K20402 DEPTOR; DEP domain-containing mTOR-interacting protein
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K11137 TELO2, TEL2; telomere length regulation protein
K20403 TTI1; TELO2-interacting protein 1
K10421 CLIP1, RSN; CAP-Gly domain-containing linker protein 1
K20064 GRB10; growth factor receptor-bound protein 10
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K08271 STRADA, LYK5; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39, MO25; calcium binding protein 39
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K20396 TBC1D7; TBC1 domain family member 7
K07208 RHEB; Ras homolog enriched in brain
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K20410 MAPKAP1, SIN1, AVO1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
K08267 RICTOR; rapamycin-insensitive companion of mTOR
K20411 PRR5, PROTOR; proline-rich protein 5
K04513 RHOA; Ras homolog gene family, member A
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
04144 Endocytosis [PATH:ko04144]
|
04145 Phagosome [PATH:ko04145]
|
04142 Lysosome [PATH:ko04142]
|
04146 Peroxisome [PATH:ko04146]
|
04140 Autophagy - animal [PATH:ko04140]
|
K04526 INS; insulin
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07207 TSC2; tuberous sclerosis 2
K07206 TSC1; tuberous sclerosis 1
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K07208 RHEB; Ras homolog enriched in brain
K07204 RAPTOR; regulatory associated protein of mTOR
K20402 DEPTOR; DEP domain-containing mTOR-interacting protein
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K17606 IGBP1, TAP42; immunoglobulin-binding protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K08331 ATG13; autophagy-related protein 13
K19730 ATG101; autophagy-related protein 101
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K22991 WDR45, WIPI4, WIPI3; WD repeat-containing protein 45
K17907 ATG9; autophagy-related protein 9
K21245 SUPT20H; transcription factor SPT20 homolog
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23610 WDR41; WD repeat-containing protein 41
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K14381 SQSTM1; sequestosome 1
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K07874 RAB1A; Ras-related protein Rab-1A
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02158 BAD; Bcl-2-antagonist of cell death
K08334 BECN, VPS30, ATG6; beclin
K21246 NRBF2; nuclear receptor-binding factor 2
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K21247 TP53INP2; tumor protein p53-inducible nuclear protein 2
K21248 VMP1; vacuole membrane protein 1
K08491 STX17; syntaxin 17
K21249 UVRAG; UV radiation resistance-associated gene protein
K11248 SH3GLB1; endophilin-B1
K19330 RUBCN; run domain Beclin-1 interacting and cysteine-rich containing protein
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K10802 HMGB1; high mobility group protein B1
K21250 PRAP1; proline-rich acidic protein 1
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K18082 MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
K18086 MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
K08336 ATG12; ubiquitin-like protein ATG12
K08339 ATG5; autophagy-related protein 5
K17890 ATG16L1; autophagy-related protein 16-1
K20868 ATG16L2; autophagy-related protein 16-2
K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
K17888 ATG10L, ATG10; ubiquitin-like-conjugating enzyme ATG10
K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K07920 RAB33B; Ras-related protein Rab-33B
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K10435 MAP1LC; microtubule-associated protein 1 light chain
K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
K17987 NBR1; next to BRCA1 gene 1 protein
K19946 OPTN, FIP2; optineurin
K21348 CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
K21347 TAX1BP1; Tax1-binding protein 1
K22262 WDFY3, ALFY; WD repeat and FYVE domain-containing protein 3
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K08509 SNAP29; synaptosomal-associated protein 29
K08512 VAMP8; vesicle-associated membrane protein 8
K08516 YKT6; synaptobrevin homolog YKT6
K08488 STX7; syntaxin 7
K23883 EPG5; ectopic P granules protein 5
K23282 PLEKHM1; pleckstrin homology domain-containing family M member 1
K20179 VPS11, PEP5; vacuolar protein sorting-associated protein 11
K20180 VPS16; vacuolar protein sorting-associated protein 16
K20181 VPS18, PEP3; vacuolar protein sorting-associated protein 18
K20182 VPS33A; vacuolar protein sorting-associated protein 33A
K20183 VPS39, VAM6; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
K20184 VPS41; vacuolar protein sorting-associated protein 41
K10586 BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
K26797 GORASP, GRASP65_55; golgi reassembly-stacking protein
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K06528 LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01363 CTSB; cathepsin B [EC:3.4.22.1]
|
04138 Autophagy - yeast [PATH:ko04138]
|
04136 Autophagy - other [PATH:ko04136]
|
04137 Mitophagy - animal [PATH:ko04137]
|
04139 Mitophagy - yeast [PATH:ko04139]
|
04148 Efferocytosis [PATH:ko04148]
|
|
09143 Cell growth and death
|
|
09144 Cellular community - eukaryotes
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
|
09150 Organismal Systems
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
K17002 MIR17; microRNA 17
K17003 MIR18A; microRNA 18a
K17005 MIR19A; microRNA 19a
K23559 MIR19B; microRNA 19b
K17006 MIR20A; microRNA 20a
K17008 MIR92A; microRNA 92a
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K17010 MIR221; microRNA 221
K17011 MIR222; microRNA 222
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K16863 MIR21; microRNA 21
K16866 TIMP3; metalloproteinase inhibitor 3
K16980 MIRLET7; microRNA let-7
K17397 MIRLET7C; microRNA let-7c
K07827 KRAS, KRAS2; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K17396 MIR107; microRNA 107
K16986 MIR15A; microRNA 15a
K16987 MIR15B; microRNA 15b
K16988 MIR16; microRNA 16
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K16978 MIR126; microRNA 126
K04438 CRK, CRKII; C-crk adapter molecule crk
K16972 MIR1; microRNA 1
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K16995 MIR29A; microRNA 29a
K16996 MIR29B; microRNA 29b
K16997 MIR29C; microRNA 29c
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K16970 MIR133A; microRNA 133a
K16971 MIR133B; microRNA 133b
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K16974 MIR145; microRNA 145
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K17017 MIR200C; microRNA 200c
K09299 ZEB1; zinc finger homeobox protein 1
K17018 MIR141; microRNA 141
K13376 TGFB2; transforming growth factor beta-2
K17116 MIR183; microRNA 183
K08007 EZR, VIL2; ezrin
K16993 MIR125A; microRNA 125a
K16994 MIR125B; microRNA 125b
K16865 PDCD4; programmed cell death protein 4
K17023 MIR143; microRNA 143
K17131 MIR192; microRNA 192
K17371 MIR194; microRNA 194
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K17167 MIR215; microRNA 215
K17366 MIR28; microRNA 28
K17110 MIR30A_D_E; microRNA 30a/d/e
K17111 MIR30B; microRNA 30b
K17040 MIR30C; microRNA 30c
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K17009 MIR155; microRNA 155
K16975 MIR203; microRNA 203
K17150 MIR205; microRNA 205
K17112 MIR27A; microRNA 27a
K17113 MIR27B; microRNA 27b
K08670 ST14, PRSS14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17183 MIR31; microRNA 31
K17367 MIR99A; microRNA 99a
K17041 MIR100; microRNA 100
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K16976 MIR375; microRNA 375
K17379 MIR602; microRNA 602
K09850 RASSF1; Ras association domain-containing protein 1
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K17042 MIR224; microRNA 224
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K17036 MIR363; microRNA 363
K17378 MIR494; microRNA 494
K17380 MIR615; microRNA 615
K17381 MIR625; microRNA 625
K17038 MIR25; microRNA 25
K16982 MIR34A; microRNA 34a
K17114 MIR96; microRNA 96
K16864 MIR10A; microRNA 10a
K17165 MIR23A; microRNA 23a
K17394 MIR23B; microRNA 23b
K17395 MIR23C; microRNA 23c
K17020 MIR122; microRNA 122
K13863 SLC7A1, ATRC1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K17024 MIR150; microRNA 150
K17001 MIR223; microRNA 223
K04381 STMN1; stathmin 1
K17132 MIR342; microRNA 342
K17376 MIR423; microRNA 423
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K17119 MIR199B; microRNA 199b
K17152 MIR324; microRNA 324
K17137 MIR483; microRNA 483
K16984 MIR26A; microRNA 26a
K16985 MIR26B; microRNA 26b
K17370 MIR152; microRNA 152
K00558 DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K17144 MIR135; microRNA 135
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K17015 MIR200A; microRNA 200a
K17016 MIR200B; microRNA 200b
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK, ST15; reversion-inducing-cysteine-rich protein with kazal motifs
K17126 MIR124; microRNA 124
K17369 MIR137; microRNA 137
K17130 MIR128; microRNA 128
K06620 E2F3; transcription factor E2F3
K17365 MIR7; microRNA 7
K07187 IRS2; insulin receptor substrate 2
K17372 MIR326; microRNA 326
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K11459 PCGF4, BMI1; polycomb group RING finger protein 4
K17012 MIR146A; microRNA 146a
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K17025 MIR181A; microRNA 181a
K17026 MIR181B; microRNA 181b
K17027 MIR181C; microRNA 181c
K17028 MIR181D; microRNA 181d
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K17000 MIR373; microRNA 373
K17175 MIR520; microRNA 520
K06256 CD44; CD44 antigen
K16989 MIR103; microRNA 103
K11592 DICER1, DCR1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5, CD49e; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K17148 MIR193B; microRNA 193b
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K17442 ZFPM2, FOG2; zinc finger protein ZFPM2
K06493 ITGB3, CD61; integrin beta 3
K10577 UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I
K17033 MIR335; microRNA 335
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K16973 MIR206; microRNA 206
K17172 MIR451; microRNA 451
K05658 ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K17375 MIR345; microRNA 345
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K17151 MIR214; microRNA 214
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K17035 MIR106B; microRNA 106b
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K17178 MIR210; microRNA 210
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K16983 MIR34B; microRNA 34b
K23572 MIR34C; microRNA 34c
K16977 MIR9; microRNA 9
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K17118 MIR199A; microRNA 199a
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4, MDMX; protein Mdm4
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K17129 MIR101; microRNA 101
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K17029 MIR195; microRNA 195
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17368 MIR129; microRNA 129
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K17039 MIR32; microRNA 32
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K17377 MIR449A; microRNA 449a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA, GLS; glutaminase [EC:3.5.1.2]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17373 MIR330; microRNA 330
K17374 MIR331; microRNA 331
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K17389 MIR520C; microRNA 520c
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
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05205 Proteoglycans in cancer [PATH:ko05205]
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05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
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05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
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05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
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05203 Viral carcinogenesis [PATH:ko05203]
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05230 Central carbon metabolism in cancer [PATH:ko05230]
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05231 Choline metabolism in cancer [PATH:ko05231]
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05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
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09162 Cancer: specific types
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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