KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
 
   09144 Cellular community - eukaryotes
     04510 Focal adhesion [PATH:ko04510]
       K06236  COL1A; collagen type I alpha
       K19719  COL2A; collagen type II alpha
       K06237  COL4A; collagen type IV alpha
       K06238  COL6A; collagen type VI alpha
       K08131  COL9A; collagen type IX alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06248  CHAD; chondroadherin
       K06249  RELN; reelin [EC:3.4.21.-]
       K16857  THBS1; thrombospondin 1
       K04659  THBS2S; thrombospondin 2/3/4/5
       K05717  FN1; fibronectin 1
       K06250  SPP1, BNSP, OPN; secreted phosphoprotein 1
       K06251  VTN; vitronectin
       K06252  TN; tenascin
       K03900  VWF; von Willebrand factor
       K06253  IBSP; integrin binding sialoprotein
       K06480  ITGA1, CD49a; integrin alpha 1
       K06481  ITGA2, CD49b; integrin alpha 2
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06482  ITGA3, CD49c; integrin alpha 3
       K06483  ITGA4, CD49d; integrin alpha 4
       K06484  ITGA5, CD49e; integrin alpha 5
       K06485  ITGA6, CD49f; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV, CD51; integrin alpha V
       K05719  ITGB1, CD29; integrin beta 1
       K06493  ITGB3, CD61; integrin beta 3
       K06525  ITGB4, CD104; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K26256  EMP2; epithelial membrane protein 2
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K04357  EGF; epidermal growth factor
       K05459  IGF1; insulin-like growth factor 1
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K26255  EMP1; epithelial membrane protein 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
       K13709  ARHGAP5; Rho GTPase-activating protein 5
       K04513  RHOA; Ras homolog gene family, member A
       K05740  DIAPH1; diaphanous 1
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10351  MYL2; myosin regulatory light chain 2
       K12753  MYL5; myosin regulatory light chain 5
       K12754  MYL7; myosin regulatory light chain 7
       K12755  MYL9; myosin regulatory light chain 9
       K12756  MYL10; myosin regulatory light chain 10
       K12757  MYL12; myosin regulatory light chain 12
       K12758  MYLPF; fast skeletal myosin light chain 2
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K00889  PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K05692  ACTB_G1; actin beta/gamma 1
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K05699  ACTN1_4; actinin alpha 1/4
       K06271  TLN; talin
       K04437  FLNA; filamin-A
       K27392  FLNB; filamin-B
       K05760  PXN; paxillin
       K06272  ILK; integrin-linked kinase [EC:2.7.11.1]
       K06273  ZYX; zyxin
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05700  VCL; vinculin
       K06275  PARV; parvin
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02105  CTNNB1; catenin beta 1
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K05736  PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
       K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
       K04393  CDC42; cell division control protein 42
       K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
       K04438  CRK, CRKII; C-crk adapter molecule crk
       K13708  DOCK1; dedicator of cytokinesis protein 1
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K06278  CAV1; caveolin 1
       K12958  CAV2; caveolin 2
       K12959  CAV3; caveolin 3
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K04364  GRB2; growth factor receptor-bound protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04503  CCND1; G1/S-specific cyclin-D1
       K10151  CCND2; G1/S-specific cyclin-D2
       K10152  CCND3; G1/S-specific cyclin-D3
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K02158  BAD; Bcl-2-antagonist of cell death
       K02161  BCL2; apoptosis regulator Bcl-2
     04520 Adherens junction [PATH:ko04520]
     04530 Tight junction [PATH:ko04530]
     04540 Gap junction [PATH:ko04540]
     04550 Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
     02030 Bacterial chemotaxis [PATH:ko02030]
     02040 Flagellar assembly [PATH:ko02040]
     04814 Motor proteins [PATH:ko04814]
     04820 Cytoskeleton in muscle cells [PATH:ko04820]
     04810 Regulation of actin cytoskeleton [PATH:ko04810]
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K10031  CXCL12; C-X-C motif chemokine 12
       K04189  CXCR4, CD184; C-X-C chemokine receptor type 4
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04526  INS; insulin
       K04357  EGF; epidermal growth factor
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22603  FGF19; fibroblast growth factor 19
       K22429  FGF21; fibroblast growth factor 21
       K22428  FGF23; fibroblast growth factor 23
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05086  INSRR; insulin receptor-related receptor [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05717  FN1; fibronectin 1
       K06480  ITGA1, CD49a; integrin alpha 1
       K06481  ITGA2, CD49b; integrin alpha 2
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06482  ITGA3, CD49c; integrin alpha 3
       K06483  ITGA4, CD49d; integrin alpha 4
       K06484  ITGA5, CD49e; integrin alpha 5
       K06485  ITGA6, CD49f; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV, CD51; integrin alpha V
       K05718  ITGAL, CD11a; integrin alpha L
       K06461  ITGAM, CD11b; integrin alpha M
       K06462  ITGAX, CD11c; integrin alpha X
       K06594  ITGAD, CD11d; integrin alpha D
       K06524  ITGAE, CD103; integrin alpha E
       K05719  ITGB1, CD29; integrin beta 1
       K06464  ITGB2, CD18; integrin beta 2
       K06493  ITGB3, CD61; integrin beta 3
       K06525  ITGB4, CD104; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K03898  KNG, BK; kininogen
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04132  CHRM4; muscarinic acetylcholine receptor M4
       K04133  CHRM5; muscarinic acetylcholine receptor M5
       K03994  C5; complement component 5
       K03995  C6; complement component 6
       K03996  C7; complement component 7
       K03997  C8A; complement component 8 subunit alpha
       K03998  C8B; complement component 8 subunit beta
       K03999  C8G; complement component 8 subunit gamma
       K04000  C9; complement component 9
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K05720  FGD1; FYVE, RhoGEF and PH domain containing 1
       K05722  FGD3; FYVE, RhoGEF and PH domain containing 3
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
       K04438  CRK, CRKII; C-crk adapter molecule crk
       K13708  DOCK1; dedicator of cytokinesis protein 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K05729  ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K05730  VAV; guanine nucleotide exchange factor VAV
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K26108  RGCC, RGC32; regulator of cell cycle RGCC
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
       K04513  RHOA; Ras homolog gene family, member A
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K05736  PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
       K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
       K13710  ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
       K05737  GIT1; G protein-coupled receptor kinase interactor 1
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K10351  MYL2; myosin regulatory light chain 2
       K12753  MYL5; myosin regulatory light chain 5
       K12754  MYL7; myosin regulatory light chain 7
       K12755  MYL9; myosin regulatory light chain 9
       K12756  MYL10; myosin regulatory light chain 10
       K12757  MYL12; myosin regulatory light chain 12
       K12758  MYLPF; fast skeletal myosin light chain 2
       K10352  MYH9s; myosin heavy chain 9/10/11/14
       K05740  DIAPH1; diaphanous 1
       K05741  DIAPH2; diaphanous 2
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K00889  PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K00920  PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
       K00921  PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
       K05743  LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
       K05744  LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
       K05745  DIAPH3, DRF3; diaphanous 3
       K05627  BAIAP2, IRSP53; BAI1-associated protein 2
       K05746  ENAH, MENA; enabled
       K23612  WASL; neural Wiskott-Aldrich syndrome protein
       K05748  WASF2; WAS protein family, member 2
       K05749  CYFIP; cytoplasmic FMR1 interacting protein
       K05750  NCKAP1, NAP125; NCK-associated protein 1
       K05751  ABI2; abl interactor 2
       K05752  C3ORF10, HSPC300; chromosome 3 open reading frame 10
       K05753  WASF1; WAS protein family, member 1
       K17260  ACTR2, ARP2; actin-related protein 2
       K18584  ACTR3, ARP3; actin-related protein 3
       K05757  ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
       K05758  ARPC2; actin related protein 2/3 complex, subunit 2
       K05756  ARPC3; actin related protein 2/3 complex, subunit 3
       K05755  ARPC4; actin related protein 2/3 complex, subunit 4
       K05754  ARPC5; actin related protein 2/3 complex, subunit 5
       K05692  ACTB_G1; actin beta/gamma 1
       K05759  PFN; profilin
       K05760  PXN; paxillin
       K08007  EZR, VIL2; ezrin
       K05762  RDX; radixin
       K05763  MSN; moesin
       K05764  TMSB4; thymosin, beta 4
       K05765  CFL; cofilin
       K05766  SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
       K05700  VCL; vinculin
       K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
       K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
       K05768  GSN; gelsolin
       K05699  ACTN1_4; actinin alpha 1/4
       K02085  APC; adenomatosis polyposis coli protein
       K05769  ARHGEF4_29, ASEF1_2; Rho guanine nucleotide exchange factor 4/29
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04922 Glucagon signaling pathway [PATH:ko04922]
     04923 Regulation of lipolysis in adipocytes [PATH:ko04923]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04929 GnRH secretion [PATH:ko04929]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
       K05243  OXT; oxytocin-neurophysin 1
       K04229  OXTR; oxytocin receptor
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04503  CCND1; G1/S-specific cyclin-D1
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04961  RYR1; ryanodine receptor 1
       K04962  RYR2; ryanodine receptor 2
       K04963  RYR3; ryanodine receptor 3
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K04977  TRPM2; transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
       K04996  KCNJ2, KIR2.1; potassium inwardly-rectifying channel subfamily J member 2
       K05005  KCNJ12_18, KIR2.2, KIR2.6; potassium inwardly-rectifying channel subfamily J member 12/18
       K04998  KCNJ4, KIR2.3; potassium inwardly-rectifying channel subfamily J member 4
       K05007  KCNJ14, KIR2.4; potassium inwardly-rectifying channel subfamily J member 14
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K18154  RGS2; regulator of G-protein signaling 2
       K17901  RCAN1, MCIP1; calcipressin-1
       K07359  CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K08794  CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K12334  NPPA; natriuretic peptide A
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K05692  ACTB_G1; actin beta/gamma 1
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04997  KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9, KIR3.3; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
     04926 Relaxin signaling pathway [PATH:ko04926]
     04935 Growth hormone synthesis, secretion and action [PATH:ko04935]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04928 Parathyroid hormone synthesis, secretion and action [PATH:ko04928]
     04916 Melanogenesis [PATH:ko04916]
     04924 Renin secretion [PATH:ko04924]
     04614 Renin-angiotensin system [PATH:ko04614]
     04925 Aldosterone synthesis and secretion [PATH:ko04925]
     04927 Cortisol synthesis and secretion [PATH:ko04927]
 
   09153 Circulatory system
     04260 Cardiac muscle contraction [PATH:ko04260]
     04261 Adrenergic signaling in cardiomyocytes [PATH:ko04261]
     04270 Vascular smooth muscle contraction [PATH:ko04270]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K09821  AGT, SERPINA8; angiotensinogen
       K04166  AGTR1; angiotensin II receptor type 1
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K04197  EDNRA; endothelin receptor type A
       K05242  AVP; arginine vasopressin
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K07425  CYP4A; long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
       K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K02183  CALM; calmodulin
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K10352  MYH9s; myosin heavy chain 9/10/11/14
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K12327  CALD1; caldesmon
       K12313  ACTA2; actin, aortic smooth muscle
       K12315  ACTG2; actin, gamma-enteric smooth muscle
       K12328  PPP1R14A, CPI17; protein phosphatase 1 regulatory subunit 14A
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K12331  ARHGEF11; Rho guanine nucleotide exchange factor 11
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04263  PTGIR; prostacyclin receptor
       K12332  CALC; calcitonin
       K12333  ADM; adrenomedullin
       K25343  ADM2; adrenomedullin-2
       K04577  CALCRL; calcitonin receptor-like
       K08447  RAMP1; receptor activity modifying protein 1
       K08448  RAMP2; receptor activity modifying protein 2
       K08449  RAMP3; receptor activity modifying protein 3
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K12334  NPPA; natriuretic peptide A
       K12335  NPPB; natriuretic peptide B
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12336  NPPC; natriuretic peptide C
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K07376  PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
       K12337  MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:ko05200]
     05202 Transcriptional misregulation in cancer [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
       K06256  CD44; CD44 antigen
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06106  CTTN, EMS1; cortactin
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-bound protein 2
       K05730  VAV; guanine nucleotide exchange factor VAV
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
       K04393  CDC42; cell division control protein 42
       K04375  ELK1; ETS domain-containing protein Elk-1
       K08550  ESR1, NR3A1; estrogen receptor alpha
       K04503  CCND1; G1/S-specific cyclin-D1
       K05692  ACTB_G1; actin beta/gamma 1
       K04437  FLNA; filamin-A
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10380  ANK1; ankyrin-1
       K09255  ANK2, ANKB; ankyrin-2
       K09259  ANK3, ANKG; ankyrin-3
       K09593  GAB1; GRB2-associated-binding protein 1
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K10164  NANOG; homeobox protein Nanog
       K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
       K03685  rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
       K04692  STAT3; signal transducer and activator of transcription 3
       K16863  MIR21; microRNA 21
       K09069  TWIST; twist
       K16864  MIR10A; microRNA 10a
       K17393  MIR10B; microRNA 10b
       K09295  HOXD10; homrobox protein Hox-D10
       K04660  DCN; decorin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06278  CAV1; caveolin 1
       K12958  CAV2; caveolin 2
       K12959  CAV3; caveolin 3
       K06497  CD63, MLA1, TSPAN30; CD63 antigen
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K13375  TGFB1; transforming growth factor beta-1
       K10159  TLR2, CD282; toll-like receptor 2
       K10160  TLR4, CD284; toll-like receptor 4
       K16865  PDCD4; programmed cell death protein 4
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K05425  IL12B; interleukin 12B
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K04377  MYC; Myc proto-oncogene protein
       K02105  CTNNB1; catenin beta 1
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09108  TFAP4; transcription factor AP-4
       K05448  VEGFA; vascular endothelial growth factor A
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
       K16866  TIMP3; metalloproteinase inhibitor 3
       K16857  THBS1; thrombospondin 1
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K08122  LUM; lumican
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K04451  TP53, P53; tumor protein p53
       K13376  TGFB2; transforming growth factor beta-2
       K04500  SMAD2; mothers against decapentaplegic homolog 2
       K07964  HPSE; heparanase [EC:3.2.1.166]
       K07965  HPSE2; heparanase 2 [EC:3.2.1.-]
       K06257  SDC1, CD138; syndecan 1
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K03985  PLAUR, CD87; plasminogen activator, urokinase receptor
       K06236  COL1A; collagen type I alpha
       K06481  ITGA2, CD49b; integrin alpha 2
       K05719  ITGB1, CD29; integrin beta 1
       K06251  VTN; vitronectin
       K06487  ITGAV, CD51; integrin alpha V
       K06493  ITGB3, CD61; integrin beta 3
       K05717  FN1; fibronectin 1
       K06588  ITGB5; integrin beta 5
       K05460  HGF; hepatocyte growth factor
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4, CD344; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10, CD349_50; frizzled 9/10
       K06484  ITGA5, CD49e; integrin alpha 5
       K16336  SDC2, CD362; syndecan 2
       K08007  EZR, VIL2; ezrin
       K05762  RDX; radixin
       K05763  MSN; moesin
       K16338  SDC4; syndecan 4
       K18497  FGF2; fibroblast growth factor 2
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K12461  FRS2; fibroblast growth factor receptor substrate 2
       K07293  PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K16867  NUDT16L1, SDOS; NUDT16-like protein 1
       K05760  PXN; paxillin
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K08107  GPC1; glypican 1
       K13769  IGF2; insulin-like growth factor 2
       K08109  GPC3; glypican 3
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K11988  SHH; sonic hedgehog
       K11989  IHH; indian hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06255  HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
       K01365  CTSL; cathepsin L [EC:3.4.22.15]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K09543  HSPB2; heat shock protein beta-2
       K05697  PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
     05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
     05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
     05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
     05203 Viral carcinogenesis [PATH:ko05203]
     05230 Central carbon metabolism in cancer [PATH:ko05230]
     05231 Choline metabolism in cancer [PATH:ko05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
     01000 Enzymes [BR:ko01000]
     01001 Protein kinases [BR:ko01001]
     01009 Protein phosphatases and associated proteins [BR:ko01009]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K08050  PPP1R1A; protein phosphatase 1 regulatory subunit 1A
       K15494  PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
       K17549  PPP1R1C; protein phosphatase 1 regulatory subunit 1C
       K16833  PPP1R2, IPP2; protein phosphatase inhibitor 2
       K07189  PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
       K17453  PPP1R3F, R3F; protein phosphatase 1 regulatory subunit 3F
       K17550  PPP1R7, SDS22; protein phosphatase 1 regulatory subunit 7
       K13216  PPP1R8, NIPP1; nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-]
       K17551  PPP1R9; neurabin
       K17552  PPP1R10; protein phosphatase 1 regulatory subunit 10
       K17553  PPP1R11; protein phosphatase 1 regulatory subunit 11
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K16823  TP53BP2, ASPP2; apoptosis-stimulating of p53 protein 2
       K17554  PPP1R13B, ASPP1; apoptosis-stimulating of p53 protein 1
       K12328  PPP1R14A, CPI17; protein phosphatase 1 regulatory subunit 14A
       K17555  PPP1R14B; protein phosphatase 1 regulatory subunit 14B
       K17556  PPP1R14C, KEPI; protein phosphatase 1 regulatory subunit 14C
       K17557  PPP1R14D, GBPI; protein phosphatase 1 regulatory subunit 14D
       K14019  PPP1R15A, GADD34; protein phosphatase 1 regulatory subunit 15A
       K17558  PPP1R15B, CREP; protein phosphatase 1 regulatory subunit 15B
       K17458  PPP1R16A, MYPT3; protein phosphatase 1 regulatory subunit 16A
       K17459  PPP1R16B, TIMAP; protein phosphatase 1 regulatory inhibitor subunit 16B
       K08067  PPP1R17, GSBS; protein phosphatase 1 regulatory subunit 17
       K17559  PPP1R18; phostensin
       K17560  URI1; unconventional prefoldin RPB5 interactor 1
       K17561  CCDC8; coiled-coil domain-containing protein 8
       K17562  PPP1R21, CCDC128, KLRAQ1; protein phosphatase 1 regulatory subunit 21
       K17563  CHCHD3; MICOS complex subunit MIC19
       K17564  CHCHD6; MICOS complex subunit MIC25
       K17495  CSMD; CUB and sushi domain-containing protein
       K14806  DDX31, DBP7; ATP-dependent RNA helicase DDX31/DBP7 [EC:5.6.2.7]
       K17565  PPP1R26; protein phosphatase 1 regulatory subunit 26
       K17566  PPP1R27; protein phosphatase 1 regulatory subunit 27
       K17567  ELFN1; protein phosphatase 1 regulatory subunit 28
       K17568  ELFN2; protein phosphatase 1 regulatory subunit 29
       K17569  GPATCH2; G patch domain-containing protein 2
       K17570  HYDIN; hydrocephalus-inducing protein
       K17571  PPP1R32; protein phosphatase 1 regulatory subunit 32
       K17572  ARFGEF3, KEPI; brefeldin A-inhibited guanine nucleotide-exchange protein 3
       K17573  LKAP, MARF1; meiosis arrest female protein 1
       K17574  PPP1R35; protein phosphatase 1 regulatory subunit 35
       K17575  PPP1R36; protein phosphatase 1 regulatory subunit 36
       K17576  PPP1R37, LRRC68; protein phosphatase 1 regulatory subunit 37
       K17577  SH2D4A; SH2 domain-containing protein 4A
       K12171  SH3RF, POSH; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
       K12018  TRIM42; tripartite motif-containing protein 42
       K17578  ZCCHC9; zinc finger CCHC domain-containing protein 9
       K17579  PPP1R42, LRRC67; protein phosphatase 1 regulatory subunit 42
       K16518  AKAP1; A-kinase anchor protein 1, mitochondrial
       K16527  AKAP11; A-kinase anchor protein 11
       K16551  AKAP9, AKAP350; A-kinase anchor protein 9
       K02085  APC; adenomatosis polyposis coli protein
       K11481  AURKA; aurora kinase A [EC:2.7.11.1]
       K11479  AURKB; aurora kinase B [EC:2.7.11.1]
       K02157  AXIN1; axin 1
       K02161  BCL2; apoptosis regulator Bcl-2
       K02163  BCLW; apoptosis regulator BCL-W
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K10605  BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
       K17580  CASC1; cancer susceptibility candidate protein 1
       K11542  CASC5, KNL1; protein CASC5
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02186  CASP2; caspase 2 [EC:3.4.22.55]
       K12075  DLG2; discs large protein 2
       K21098  DLG3; discs large protein 3
       K13099  CD2BP2, PPP1R59; CD2 antigen cytoplasmic tail-binding protein 2
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K11498  CENPE, KIF10; centromeric protein E
       K16725  CEP192; centrosomal protein CEP192
       K05016  CLCN7; chloride channel 7
       K17581  CNST; consortin
       K15502  ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
       K10642  DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]
       K03238  EIF2S2; translation initiation factor 2 subunit 2
       K15183  ELL; RNA polymerase II elongation factor ELL
       K04679  MADHIP, SARA; MAD, mothers against decapentaplegic interacting protein
       K11248  SH3GLB1; endophilin-B1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K17494  CSRNP; cysteine/serine-rich nuclear protein
       K08889  FER, TYK3; tyrosine-protein kinase Fer [EC:2.7.10.2]
       K17477  FARP1; FERM, RhoGEF and pleckstrin domain-containing protein 1
       K17478  FKBP15, WAFL; FK506-binding protein 15
       K03504  POLD3; DNA polymerase delta subunit 3
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K04315  GPR12; G protein-coupled receptor 12
       K17479  GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
       K14966  HCFC1; host cell factor 1
       K11407  HDAC6; histone deacetylase 6 [EC:3.5.1.98]
       K09220  IKZF, ZNFN1A; IKAROS family zinc finger protein
       K06476  ITGA2B, CD41; integrin alpha 2B
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K01251  AHCY, ahcY; adenosylhomocysteinase [EC:3.13.2.1]
       K11446  KDM5, JARID1; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]
       K04879  KCNA6, KV1.6; potassium voltage-gated channel Shaker-related subfamily A member 6
       K04920  KCNK10, K2P10.1; potassium channel subfamily K member 10
       K08898  LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
       K02932  RP-L5e, RPL5; large subunit ribosomal protein L5e
       K17480  AATK, LMTK1; lemur tyrosine kinase 1 [EC:2.7.10.1]
       K08899  LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]
       K10429  MAP1; microtubule-associated protein 1
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:5.6.2.3]
       K04603  GRM1; metabotropic glutamate receptor 1
       K04608  GRM6; metabotropic glutamate receptor 6
       K04609  GRM7; metabotropic glutamate receptor 7
       K04610  GRM8; metabotropic glutamate receptor 8
       K17582  MKI67; antigen KI-67
       K14559  MPP10; U3 small nucleolar RNA-associated protein MPP10
       K10356  MYO1; myosin I
       K17481  MYO16; myosin XVI
       K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
       K20872  NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
       K04572  NEFL, NF-L; neurofilament light polypeptide
       K17493  CAMSAP; calmodulin-regulated spectrin-associated protein
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
       K17583  NOM1; nucleolar MIF4G domain-containing protein 1
       K06088  OCLN; occludin
       K04256  OPN3; c-opsin
       K02607  ORC5; origin recognition complex subunit 5
       K04237  PARD3; partitioning defective protein 3
       K17584  PCIF1; phosphorylated CTD-interacting factor 1
       K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
       K17594  PHACTR; phosphatase and actin regulator
       K17586  PHRF1; PHD and RING finger domain-containing protein 1
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K17587  TMEM225; transmembrane protein 225
       K17588  PREX2; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
       K15375  PLCL1, PRIP; inactive phospholipase C-like protein 1
       K16498  PCDHD1; protocadherin delta 1
       K13219  SFPQ, PSF; splicing factor, proline- and glutamine-rich
       K06618  RB1; retinoblastoma-associated protein
       K17589  RB1CC1; RB1-inducible coiled-coil protein 1
       K13192  RBM26; RNA-binding protein 26
       K17590  CDCA2; cell division cycle-associated protein 2
       K17591  RIMBP2; RIMS-binding protein 2
       K16550  RPGRIP1L; protein fantom
       K14849  RRP1; ribosomal RNA-processing protein 1
       K04961  RYR1; ryanodine receptor 1
       K17592  SACS; sacsin
       K17593  ANKRD42, SARP; ankyrin repeat domain-containing protein 42
       K12866  WBP11, NPWBP; WW domain-binding protein 11
       K11648  SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
       K13871  SLC7A14; solute carrier family 7 (cationic amino acid transporter), member 14
       K17595  SPATA2; spermatogenesis-associated protein 2
       K17596  SPOCD1; SPOC domain-containing protein 1
       K04703  SPRED; sprouty-related, EVH1 domain-containing protein
       K17482  SPZ1; spermatogenic leucine zipper protein 1
       K12900  SRSF10, FUSIP1; serine/arginine-rich splicing factor 10
       K17597  STAU; double-stranded RNA-binding protein Staufen
       K17598  SYTL; synaptotagmin-like protein
       K04380  MAPT, TAU; microtubule-associated protein tau
       K17599  TMEM132; transmembrane protein 132
       K12897  TRA2; transformer-2 protein
       K11796  TRPC4AP; Trpc4-associated protein
       K04968  TRPC5; transient receptor potential cation channel subfamily C member 5
       K07207  TSC2; tuberous sclerosis 2
       K16492  TSKS; testis-specific serine kinase substrate
       K17492  UBN; ubinuclein
       K08539  VDR, NR1I1; vitamin D3 receptor
       K17600  VPS54; vacuolar protein sorting-associated protein 54
       K17601  WDR81; WD repeat-containing protein 81
       K08867  WNK, PRKWNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
       K17602  YLPM1; YLP motif-containing protein 1
       K10510  ZBTB38; zinc finger and BTB domain-containing protein 38
       K17603  ZFYVE1; zinc finger FYVE domain-containing protein 1
       K17604  ZSWIM3; zinc finger SWIM domain-containing protein 3
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K17605  PPP2R4, PTPA; serine/threonine-protein phosphatase 2A activator
       K17606  IGBP1, TAP42; immunoglobulin-binding protein 1
       K17607  TIPRL, TIP41; type 2A phosphatase activator TIP41
       K17608  STRN1_3_4; striatin 1/3/4
       K17609  NXN; nucleoredoxin [EC:1.8.1.8]
       K18203  LCMT1; [phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233]
       K27491  ENSA, ARPP19; endosulfine family protein
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K21814  CPPED1; serine/threonine-protein phosphatase CPPED1 [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K02183  CALM; calmodulin
       K17610  CHP, CHP1; calcineurin B homologous protein 1
       K17611  CHP2; calcineurin B homologous protein 2
       K17612  TESC, CHP3; calcineurin B homologous protein 3
       K17613  CABIN1; calcineurin-binding protein cabin-1
       K16522  AKAP5; A-kinase anchor protein 5
       K09574  FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
       K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
       K15424  PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
       K15425  PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
       K17491  SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
       K15426  PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
       K04460  PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K03283  HSPA1_6_8; heat shock 70kDa protein 1/6/8
       K15498  PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
       K15427  SIT4, PPH1; serine/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]
       K17615  PPG1; serine/threonine-protein phosphatase PPG1 [EC:3.1.3.16]
       K15499  PPP6R1, SAPS1; serine/threonine-protein phosphatase 6 regulatory subunit 1
       K15500  PPP6R2, SAPS2; serine/threonine-protein phosphatase 6 regulatory subunit 2
       K15501  PPP6R3, SAPS3; serine/threonine-protein phosphatase 6 regulatory subunit 3
       K15503  ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
       K15504  ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
       K13807  PPEF, PPP7C; serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16]
       K04457  PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
       K04461  PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
       K17499  PPM1G, PP2CG; protein phosphatase 1G [EC:3.1.3.16]
       K17500  ILKAP; integrin-linked kinase-associated serine/threonine phosphatase 2C [EC:3.1.3.16]
       K10147  PPM1D, WIP1; protein phosphatase 1D [EC:3.1.3.16]
       K17501  PPM1E, POPX1; protein phosphatase 1E [EC:3.1.3.16]
       K17502  PPM1F, POPX2; protein phosphatase 1F [EC:3.1.3.16]
       K17503  PPM1H, ARHCL1; protein phosphatase 1H [EC:3.1.3.16]
       K17504  PPM1J, PP2CZ; protein phosphatase 1J [EC:3.1.3.16]
       K17505  PPM1K, PP2CM; protein phosphatase 1K [EC:3.1.3.16]
       K17506  PPM1L, PP2CE; protein phosphatase 1L [EC:3.1.3.16]
       K17507  PPM1M, PP2CE; protein phosphatase 1M [EC:3.1.3.16]
       K19790  PPM1N; protein phosphatase 1N [EC:3.1.3.16]
       K16340  PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
       K19704  PTC1; protein phosphatase PTC1 [EC:3.1.3.16]
       K14803  PTC2_3; protein phosphatase PTC2/3 [EC:3.1.3.16]
       K19705  PTC4; protein phosphatase PTC4 [EC:3.1.3.16]
       K19708  PTC6, AUP1; protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43]
       K17508  PTC7, PPTC7; protein phosphatase PTC7 [EC:3.1.3.16]
       K20074  prpC, phpP; PPM family protein phosphatase [EC:3.1.3.16]
       K01102  PDP; pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
       K17509  PDPR; pyruvate dehydrogenase phosphatase regulatory subunit
       K18032  PTPRA; receptor-type tyrosine-protein phosphatase A [EC:3.1.3.48]
       K05694  PTPRB, PTPB; receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]
       K06478  PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
       K06777  PTPRD; receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48]
       K18033  PTPRE; receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48]
       K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
       K16667  PTPRG; receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48]
       K18034  PTPRH, SAP1; receptor-type tyrosine-protein phosphatase H [EC:3.1.3.48]
       K05698  PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
       K06776  PTPRK; receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48]
       K05693  PTPRM; receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48]
       K07817  PTPRN; receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
       K18035  PTPRO; receptor-type tyrosine-protein phosphatase O [EC:3.1.3.48]
       K16910  PTPRQ; receptor-type tyrosine-protein phosphatase Q [EC:3.1.3.48]
       K04458  PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
       K06778  PTPRS; receptor-type tyrosine-protein phosphatase S [EC:3.1.3.48]
       K13297  PTPRT; receptor-type tyrosine-protein phosphatase T [EC:3.1.3.48]
       K16662  PTPRU; receptor-type tyrosine-protein phosphatase U [EC:3.1.3.48]
       K18036  PTPRV, ESP; receptor-type tyrosine-protein phosphatase V [EC:3.1.3.48]
       K08114  PTPRZ; receptor-type tyrosine-protein phosphatase zeta [EC:3.1.3.48]
       K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
       K18026  PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
       K18027  PTPN3, PTPH1; tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48]
       K18037  PTPN4, MEG; tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48]
       K18018  PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
       K05697  PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
       K18019  PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
       K18038  PTPN9, MEG2; tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48]
       K07293  PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K18024  PTPN12_18_22; tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48]
       K02374  PTPN13, FAP-1; tyrosine-protein phosphatase non-receptor type 13
       K18025  PTPN14_21; tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48]
       K18039  PTPN20; tyrosine-protein phosphatase non-receptor type 20 [EC:3.1.3.48]
       K18040  PTPN23; tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]
       K20220  PTP-ER; tyrosine-protein phosphatase ERK [EC:3.1.3.48]
       K19806  PTP2_3; tyrosine-protein phosphatase 2/3 [EC:3.1.3.48]
       K21278  DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
       K04459  DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
       K21946  DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
       K18498  DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
       K20216  DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
       K11240  MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]
       K19812  SDP1; dual-specificity protein phosphatase SDP1 [EC:3.1.3.48]
       K05766  SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
       K18041  PTP4A; protein tyrosine phosphatase type IVA [EC:3.1.3.48]
       K17614  DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
       K14819  DUSP12, YVH1; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]
       K14165  K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]
       K18042  STYX; serine/threonine/tyrosine-interacting protein
       K20551  MKP2; dual specificity protein phosphatase 1B [EC:3.1.3.16 3.1.3.48]
       K18043  OCA1; tyrosine-protein phosphatase OCA1 [EC:3.1.3.48]
       K18044  OCA2; tyrosine-protein phosphatase-like protein OCA2
       K18045  SIW14, OCA3; tyrosine-protein phosphatase SIW14 [EC:3.1.3.48]
       K18046  OCA6; tyrosine-protein phosphatase OCA6 [EC:3.1.3.48]
       K06639  CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
       K14167  CDKN3, KAP; cyclin-dependent kinase inhibitor 3 [EC:3.1.3.16 3.1.3.48]
       K18078  PTPDC1; protein tyrosine phosphatase domain-containing protein 1 [EC:3.1.3.-]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K18079  TPTE, TPIP; PTEN homologous phosphatase
       K18080  TNS; tensin
       K01108  MTM1; myotubularin [EC:3.1.3.64 3.1.3.95]
       K18081  MTMR1_2; myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95]
       K18082  MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
       K18061  SBF1_2, MTMR5_13; myotubularin-related protein 5/13
       K18083  MTMR6_7_8; myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
       K18084  MTMR9; myotubularin-related protein 9
       K18085  MTMR10_11_12; myotubularin-related protein 10/11/12
       K18086  MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
       K18993  UBASH3, STS; ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48]
       K14394  ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K18065  CDC25; Cdc25 family phosphatase [EC:3.1.3.48 1.20.4.1]
       K02555  MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
       K15732  CTDP1, FCP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]
       K15731  CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]
       K17616  CTDSPL2; CTD small phosphatase-like protein 2 [EC:3.1.3.-]
       K17617  CTDNEP1, DULLARD, NEM1; CTD nuclear envelope phosphatase 1 [EC:3.1.3.16]
       K18998  CPL1_2; RNA polymerase II C-terminal domain phosphatase-like 1/2 [EC:3.1.3.16]
       K18999  CPL3_4; RNA polymerase II C-terminal domain phosphatase-like 3/4 [EC:3.1.3.16]
       K17618  UBLCP1; ubiquitin-like domain-containing CTD phosphatase 1 [EC:3.1.3.16]
       K20827  RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]
       K17619  MDP1; magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]
       K15616  EYA1; eyes absent homolog 1 [EC:3.1.3.48]
       K17620  EYA2; eyes absent homolog 2 [EC:3.1.3.48]
       K17621  EYA3; eyes absent homolog 3 [EC:3.1.3.48]
       K17622  EYA4; eyes absent homolog 4 [EC:3.1.3.48]
       K07758  PDXP; pyridoxal phosphatase [EC:3.1.3.74]
       K19269  PGP, PGLP; phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]
       K08073  PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
       K08726  EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
       K01079  serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]
       K06124  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [EC:3.1.3.75]
       K13248  PHOSPHO2; pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74]
       K17623  PUDP, HDHD1; pseudouridine 5'-phosphatase [EC:3.1.3.96]
       K01097  NANP; N-acylneuraminate-9-phosphatase [EC:3.1.3.29]
       K11725  LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-]
       K15728  LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
     01002 Peptidases and inhibitors [BR:ko01002]
     01003 Glycosyltransferases [BR:ko01003]
     01005 Lipopolysaccharide biosynthesis proteins [BR:ko01005]
     01011 Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
     01004 Lipid biosynthesis proteins [BR:ko01004]
     01008 Polyketide biosynthesis proteins [BR:ko01008]
     01006 Prenyltransferases [BR:ko01006]
     01007 Amino acid related enzymes [BR:ko01007]
     00199 Cytochrome P450 [BR:ko00199]
     00194 Photosynthesis proteins [BR:ko00194]
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 25, 2024