phytochemical cluster No. 31 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• KCF-S cluster (1)
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Liliopsida	8

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Cumulative family count

class name	count
Zingiberaceae	8

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Diarylheptanoids	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Diarylheptanoids	C10443	C00002731

KCF-S cluster (1)

KCF-S ID	# of metabolite
No. 3613	3

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	figure
C00002731	Letestuianin A	CHEMBL478742				No. 3613
C00044863	Letestuianin B	CHEMBL518119				No. 3613
C00044864	Curcumin	CHEMBL116438	D003474	91 / 65 / 83	458 / 104	No. 3613

Human Protein / Gene in interactions

91 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002731	1 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00002731	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002731	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002731	7 / 37
Q09472	Histone acetyltransferase p300	Enzyme	C00002731	1 / 1
Q9NR96	Toll-like receptor 9	Toll-like and Il-1 receptors	C00002731	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002731	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002731	1 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002731	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002731	0 / 3
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002731	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002731	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002731	0 / 0
Q05655	Protein kinase C delta type	Delta	C00002731	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00002731	2 / 2
Q04759	Protein kinase C theta type	Delta	C00002731	0 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002731	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002731	0 / 0
P20813	Cytochrome P450 2B6	Cytochrome P450 2B6	C00002731	1 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002731	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00002731	4 / 2
P00918	Carbonic anhydrase 2	Lyase	C00002731	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00002731	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00002731	0 / 0
P08183	Multidrug resistance protein 1	drug	C00002731	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002731	0 / 1
P30291	Wee1-like protein kinase	WEE serine/threonine protein kinase subfamily	C00002731	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002731	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00002731	0 / 0
Q9UBC3	DNA (cytosine-5)-methyltransferase 3B	Enzyme	C00002731	1 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002731	1 / 8
P11387	DNA topoisomerase 1	Isomerase	C00002731	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002731	2 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002731	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00002731	0 / 0
P05067	Amyloid beta A4 protein	Membrane receptor	C00002731	2 / 2
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002731	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002731	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002731	0 / 0
P68871	Hemoglobin subunit beta	Secreted protein	C00002731	4 / 4
O43570	Carbonic anhydrase 12	Lyase	C00002731	1 / 2
Q9UQM7	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Camk2	C00002731	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002731	0 / 0
Q92993	Histone acetyltransferase KAT5	Enzyme	C00002731	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002731	2 / 0
O75496	Geminin	Unclassified protein	C00002731	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002731	0 / 0
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00002731	1 / 2
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00002731	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00002731	3 / 1
P11308	Transcriptional regulator ERG	Unclassified protein	C00002731	1 / 2
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002731	1 / 2
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00002731	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002731	0 / 0
Q99816	Tumor susceptibility gene 101 protein	Unclassified protein	C00002731	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002731	0 / 1
P14679	Tyrosinase	Oxidoreductase	C00002731	4 / 2
P06276	Cholinesterase	Hydrolase	C00002731	0 / 0
P45452	Collagenase 3	M10A	C00002731	1 / 1
P13726	Tissue factor	Membrane receptor	C00002731	0 / 0
P37058	Testosterone 17-beta-dehydrogenase 3	Enzyme	C00002731	1 / 1
P10696	Alkaline phosphatase, placental-like	Enzyme	C00002731	0 / 1
P56817	Beta-secretase 1	A1A	C00002731	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002731	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002731	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002731	3 / 3
Q99873	Protein arginine N-methyltransferase 1	Enzyme	C00002731	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002731	2 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002731	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00002731	1 / 0
P26358	DNA (cytosine-5)-methyltransferase 1	Transferase	C00002731	2 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002731	0 / 0
P35228	Nitric oxide synthase, inducible	Enzyme	C00002731	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002731	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002731	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002731	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002731	4 / 3
P10997	Islet amyloid polypeptide	Unclassified protein	C00002731	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002731	0 / 0
P05412	Transcription factor AP-1	Transcription Factor	C00002731	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00002731	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00002731	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002731	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00002731	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002731	0 / 0
P42224	Signal transducer and activator of transcription 1-alpha/beta	Unclassified protein	C00002731	3 / 3
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002731	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002731	1 / 0
O00255	Menin	Unclassified protein	C00002731	2 / 5
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002731	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002731	1 / 1

458 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
53947	A4GALT, A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK	alpha 1,4-galactosyltransferase (EC:2.4.1.228)	C00002731
16	AARS, CMT2N	alanyl-tRNA synthetase (EC:6.1.1.7)	C00002731
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002731
18669			C00002731
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00002731
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00002731
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00002731
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00002731
31	ACACA, ACAC, ACACAD, ACC, ACC1, ACCA	acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14)	C00002731
57007	ACKR3, CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1	atypical chemokine receptor 3	C00002731
6868	ADAM17, ADAM18, CD156B, CSVP, NISBD, TACE	ADAM metallopeptidase domain 17 (EC:3.4.24.86)	C00002731
9507	ADAMTS4, ADAMTS-2, ADAMTS-4, ADMP-1	ADAM metallopeptidase with thrombospondin type 1 motif, 4 (EC:3.4.24.82)	C00002731
115	ADCY9, AC9	adenylate cyclase 9 (EC:4.6.1.1)	C00002731
10551	AGR2, AG2, GOB-4, HAG-2, PDIA17, XAG-2	anterior gradient 2	C00002731
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00002731
9472	AKAP6, ADAP100, ADAP6, AKAP100, PRKA6, mAKAP	A kinase (PRKA) anchor protein 6	C00002731
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002731
226	ALDOA, ALDA, GSD12	aldolase A, fructose-bisphosphate (EC:4.1.2.13)	C00002731
230	ALDOC, ALDC	aldolase C, fructose-bisphosphate (EC:4.1.2.13)	C00002731
353322	ANKRD37, Lrp2bp	ankyrin repeat domain 37	C00002731
57182	ANKRD50	ankyrin repeat domain 50	C00002731
55139	ANKZF1, ZNF744	ankyrin repeat and zinc finger domain containing 1	C00002731
324	APC, BTPS2, DP2, DP2.5, DP3, GS, PPP1R46	adenomatous polyposis coli	C00002731
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00002731
360	AQP3, AQP-3, GIL	aquaporin 3 (Gill blood group)	C00002731
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00002731
257106	ARHGAP30	Rho GTPase activating protein 30	C00002731
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00002731
467	ATF3	activating transcription factor 3	C00002731
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00002731
126792	B3GALT6, EDSP2, SEMDJL1, beta3GalT6	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 (EC:2.4.1.134)	C00002731
23621	BACE1, ASP2, BACE, HSPC104	beta-site APP-cleaving enzyme 1 (EC:3.4.23.46)	C00002731
572	BAD, BBC2, BCL2L8	BCL2-associated agonist of cell death	C00002731
578	BAK1, BAK, BAK-LIKE, BCL2L7, CDN1	BCL2-antagonist/killer 1	C00002731
581	BAX, BCL2L4	BCL2-associated X protein	C00002731
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00002731
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002731
597	BCL2A1, ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1	BCL2-related protein A1	C00002731
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00002731
10018	BCL2L11, BAM, BIM, BOD	BCL2-like 11 (apoptosis facilitator)	C00002731
599	BCL2L2, BCL-W, BCL2-L-2, BCLW, PPP1R51	BCL2-like 2	C00002731
54880	BCOR, ANOP2, MAA2, MCOPS2	BCL6 corepressor	C00002731
637	BID, FP497	BH3 interacting domain death agonist	C00002731
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00002731
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002731
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00002731
79444	BIRC7, KIAP, LIVIN, ML-IAP, MLIAP, RNF50	baculoviral IAP repeat containing 7	C00002731
834	CASP1, ICE, IL1BC, P45	caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)	C00002731
835	CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57	caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55)	C00002731
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002731
837	CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX	caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57)	C00002731
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00002731
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00002731
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00002731
847	CAT	catalase (EC:1.11.1.6)	C00002731
55749	CCAR1, RP11-437A18.1	cell division cycle and apoptosis regulator 1	C00002731
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002731
890	CCNA2, CCN1, CCNA	cyclin A2	C00002731
891	CCNB1, CCNB	cyclin B1	C00002731
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002731
896	CCND3	cyclin D3	C00002731
898	CCNE1, CCNE	cyclin E1	C00002731
9236	CCPG1, CPR8	cell cycle progression 1	C00002731
929	CD14	CD14 molecule	C00002731
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00002731
958	CD40, Bp50, CDW40, TNFRSF5, p50	CD40 molecule, TNF receptor superfamily member 5	C00002731
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00002731
1604	CD55, CR, CROM, DAF, TC	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	C00002731
8555	CDC14B, CDC14B3, Cdc14B1, Cdc14B2, hCDC14B	cell division cycle 14B (EC:3.1.3.16 3.1.3.48)	C00002731
991	CDC20, CDC20A, bA276H19.3, p55CDC	cell division cycle 20	C00002731
995	CDC25C, CDC25, PPP1R60	cell division cycle 25C (EC:3.1.3.48)	C00002731
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00002731
1009	CDH11, CAD11, CDHOB, OB, OSF-4	cadherin 11, type 2, OB-cadherin (osteoblast)	C00002731
1015	CDH17, CDH16, HPT-1, HPT1	cadherin 17, LI cadherin (liver-intestine)	C00002731
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00002731
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00002731
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00002731
1021	CDK6, PLSTIRE	cyclin-dependent kinase 6 (EC:2.7.11.22)	C00002731
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002731
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002731
1029	CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16	cyclin-dependent kinase inhibitor 2A	C00002731
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00002731
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00002731
1111	CHEK1, CHK1	checkpoint kinase 1 (EC:2.7.11.1)	C00002731
11200	CHEK2, CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1	checkpoint kinase 2 (EC:2.7.11.1)	C00002731
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00002731
1185	CLCN6, CLC-6	chloride channel, voltage-sensitive 6	C00002731
1280	COL2A1, ANFH, AOM, COL11A3, SEDC, STL1	collagen, type II, alpha 1	C00002731
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00002731
1287	COL4A5, ASLN, ATS, CA54	collagen, type IV, alpha 5	C00002731
1387	CREBBP, CBP, KAT3A, RSTS	CREB binding protein (EC:2.3.1.48)	C00002731
1435	CSF1, CSF-1, MCSF	colony stimulating factor 1 (macrophage) (EC:2.7.10.1)	C00002731
1436	CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R	colony stimulating factor 1 receptor (EC:2.7.10.1)	C00002731
1490	CTGF, CCN2, HCS24, IGFBP8, NOV2	connective tissue growth factor	C00002731
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00002731
2919	CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	C00002731
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00002731
2920	CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2	chemokine (C-X-C motif) ligand 2	C00002731
3577	CXCR1, C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA	chemokine (C-X-C motif) receptor 1	C00002731
3579	CXCR2, CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB	chemokine (C-X-C motif) receptor 2	C00002731
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002731
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002731
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002731
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002731
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00002731
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00002731
27128	CYTH4, CYT4, DJ63G5.1, PSCD4	cytohesin 4	C00002731
1616	DAXX, BING2, DAP6, EAP1	death-domain associated protein	C00002731
1634	DCN, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B	decorin	C00002731
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00002731
115265	DDIT4L, REDD2, Rtp801L	DNA-damage-inducible transcript 4-like	C00002731
115817	DHRS1, SDR19C1	dehydrogenase/reductase (SDR family) member 1	C00002731
4189	DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049	DnaJ (Hsp40) homolog, subfamily B, member 9	C00002731
55332	DRAM1, DRAM	DNA-damage regulated autophagy modulator 1	C00002731
1843	DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10	dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48)	C00002731
11221	DUSP10, MKP-5, MKP5	dual specificity phosphatase 10 (EC:3.1.3.16 3.1.3.48)	C00002731
1847	DUSP5, DUSP, HVH3	dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48)	C00002731
1855	DVL1, DVL, DVL1L1, DVL1P1	dishevelled segment polarity protein 1	C00002731
8655	DYNLL1, DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, PIN, hdlc1	dynein, light chain, LC8-type 1	C00002731
1875	E2F5, E2F-5	E2F transcription factor 5, p130-binding	C00002731
10085	EDIL3, DEL1	EGF-like repeats and discoidin I-like domains 3	C00002731
1950	EGF, HOMG4, URG	epidermal growth factor	C00002731
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00002731
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00002731
10209	EIF1, A121, EIF-1, EIF1A, ISO1, SUI1	eukaryotic translation initiation factor 1	C00002731
1978	EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I	eukaryotic translation initiation factor 4E binding protein 1	C00002731
1981	EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18	eukaryotic translation initiation factor 4 gamma, 1	C00002731
1998	ELF2, EU32, NERF, NERF-1A, NERF-1B, NERF-1a,b, NERF-2	E74-like factor 2 (ets domain transcription factor)	C00002731
2002	ELK1	ELK1, member of ETS oncogene family	C00002731
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00002731
2033	EP300, KAT3B, RSTS2, p300	E1A binding protein p300 (EC:2.3.1.48)	C00002731
2056	EPO, EP, MVCD2	erythropoietin	C00002731
2064	ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1)	C00002731
2065	ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1)	C00002731
2067	ERCC1, COFS4, RAD10, UV20	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)	C00002731
2081	ERN1, IRE1, IRE1P, IRE1a, hIRE1p	endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1)	C00002731
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00002731
2114	ETS2, ETS2IT1	v-ets avian erythroblastosis virus E26 oncogene homolog 2	C00002731
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00002731
84498	FAM120B, CCPG, KIAA1838, PGCC1, dJ894D12.1	family with sequence similarity 120B	C00002731
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002731
2224	FDPS, FPPS, FPS	farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10)	C00002731
2263	FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25	fibroblast growth factor receptor 2 (EC:2.7.10.1)	C00002731
11259	FILIP1L, DOC-1, DOC1, GIP130, GIP90	filamin A interacting protein 1-like	C00002731
2321	FLT1, FLT, FLT-1, VEGFR-1, VEGFR1	fms-related tyrosine kinase 1 (EC:2.7.10.1)	C00002731
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00002731
2342	FNTB, FPTB	farnesyltransferase, CAAX box, beta (EC:2.5.1.58)	C00002731
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00002731
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00002731
2355	FOSL2, FRA2	FOS-like antigen 2	C00002731
3169	FOXA1, HNF3A, TCF3A	forkhead box A1	C00002731
2295	FOXF2, FKHL6, FREAC-2, FREAC2	forkhead box F2	C00002731
2308	FOXO1, FKH1, FKHR, FOXO1A	forkhead box O1	C00002731
2521	FUS, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS	fused in sarcoma	C00002731
8321	FZD1	frizzled family receptor 1	C00002731
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00002731
2621	GAS6, AXLLG, AXSF	growth arrest-specific 6	C00002731
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00002731
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00002731
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00002731
2852	GPER1, CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR	G protein-coupled estrogen receptor 1	C00002731
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00002731
2941	GSTA4, GSTA4-4, GTA4	glutathione S-transferase alpha 4 (EC:2.5.1.18)	C00002731
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00002731
283120	H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, PRO2605, WT2	H19, imprinted maternally expressed transcript (non-protein coding)	C00002731
8971	H1FX, H1X	H1 histone family, member X	C00002731
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00002731
10767	HBS1L, EF-1a, ERFS, HBS1, HSPC276	HBS1-like (S. cerevisiae)	C00002731
3065	HDAC1, GON-10, HD1, RPD3, RPD3L1	histone deacetylase 1 (EC:3.5.1.98)	C00002731
3066	HDAC2, HD2, RPD3, YAF1	histone deacetylase 2 (EC:3.5.1.98)	C00002731
8841	HDAC3, HD3, RPD3, RPD3-2	histone deacetylase 3 (EC:3.5.1.98)	C00002731
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00002731
3017	HIST1H2BD, H2B.1B, H2B/b, H2BFB, HIRIP2, dJ221C16.6	histone cluster 1, H2bd	C00002731
8363	HIST1H4J, H4/e, H4F2iv, H4FE, dJ160A22.2	histone cluster 1, H4j	C00002731
554313	HIST2H4B, H4/o	histone cluster 2, H4b	C00002731
128312	HIST3H2BB, H2Bb	histone cluster 3, H2bb	C00002731
3116	HLA-DPB2, DP2B, DPB2, DPbeta2, HLA-DP2B	major histocompatibility complex, class II, DP beta 2 (pseudogene)	C00002731
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00002731
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00002731
693712			C00002731
79256			C00002731
3215	HOXB5, HHO.C10, HOX2, HOX2A, HU-1, Hox2.1	homeobox B5	C00002731
3251	HPRT1, HGPRT, HPRT	hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8)	C00002731
3297	HSF1, HSTF1	heat shock transcription factor 1	C00002731
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00002731
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002731
3397	ID1, ID, bHLHb24	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	C00002731
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00002731
3399	ID3, HEIR-1, bHLHb25	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	C00002731
3620	IDO1, IDO, IDO-1, INDO	indoleamine 2,3-dioxygenase 1 (EC:1.13.11.52)	C00002731
3439	IFNA1, IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@	interferon, alpha 1	C00002731
3454	IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC	interferon (alpha, beta and omega) receptor 1	C00002731
3455	IFNAR2, IFN-R, IFN-alpha-REC, IFNABR, IFNARB	interferon (alpha, beta and omega) receptor 2	C00002731
3456	IFNB1, IFB, IFF, IFNB	interferon, beta 1, fibroblast	C00002731
3458	IFNG, IFG, IFI	interferon, gamma	C00002731
56832	IFNK, IFNT1, INFE1, RP11-27J8.1	interferon, kappa	C00002731
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00002731
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00002731
3486	IGFBP3, BP-53, IBP3	insulin-like growth factor binding protein 3	C00002731
3490	IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF	insulin-like growth factor binding protein 7	C00002731
3543	IGLL1, 14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2	immunoglobulin lambda-like polypeptide 1	C00002731
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00002731
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00002731
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00002731
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002731
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00002731
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002731
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002731
51141	INSIG2	insulin induced gene 2	C00002731
3684	ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6	integrin, alpha M (complement component 3 receptor 3 subunit)	C00002731
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00002731
3713	IVL	involucrin	C00002731
3717	JAK2, JTK10, THCYT3	Janus kinase 2 (EC:2.7.10.2)	C00002731
3718	JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK	Janus kinase 3 (EC:2.7.10.2)	C00002731
126306	JSRP1, JP-45, JP45	junctional sarcoplasmic reticulum protein 1	C00002731
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00002731
3726	JUNB, AP-1	jun B proto-oncogene	C00002731
3727	JUND, AP-1	jun D proto-oncogene	C00002731
10242	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2	C00002731
3791	KDR, CD309, FLK1, VEGFR, VEGFR2	kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1)	C00002731
7071	KLF10, EGR-alpha, EGRA, TIEG, TIEG1	Kruppel-like factor 10	C00002731
1316	KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9	Kruppel-like factor 6	C00002731
9903	KLHL21	kelch-like family member 21	C00002731
54800	KLHL24, DRE1, KRIP6	kelch-like family member 24	C00002731
3817	KLK2, KLK2A2, hGK-1, hK2	kallikrein-related peptidase 2 (EC:3.4.21.35)	C00002731
354	KLK3, APS, KLK2A1, PSA, hK3	kallikrein-related peptidase 3 (EC:3.4.21.77)	C00002731
3845	KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2	Kirsten rat sarcoma viral oncogene homolog	C00002731
81872	KRTAP2-1, KAP2.1A, KRTAP2.1A	keratin associated protein 2-1	C00002731
8942	KYNU	kynureninase (EC:3.7.1.3)	C00002731
3937	LCP2, SLP-76, SLP76	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	C00002731
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00002731
3980	LIG3, LIG2	ligase III, DNA, ATP-dependent (EC:6.5.1.1)	C00002731
3981	LIG4	ligase IV, DNA, ATP-dependent (EC:6.5.1.1)	C00002731
1902	LPAR1, EDG2, GPR26, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1	lysophosphatidic acid receptor 1	C00002731
4033	LRMP, JAW1	lymphoid-restricted membrane protein	C00002731
54674	LRRN3, FIGLER5, NLRR-3, NLRR3	leucine rich repeat neuronal 3	C00002731
4049	LTA, LT, TNFB, TNFSF1	lymphotoxin alpha	C00002731
4050	LTB, TNFC, TNFSF3, p33	lymphotoxin beta (TNF superfamily, member 3)	C00002731
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00002731
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00002731
5606	MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2	mitogen-activated protein kinase kinase 3 (EC:2.7.12.2)	C00002731
6416	MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1	mitogen-activated protein kinase kinase 4 (EC:2.7.12.2)	C00002731
4214	MAP3K1, MAPKKK1, MEKK, MEKK_1, MEKK1, SRXY6	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase (EC:2.7.11.25)	C00002731
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002731
6300	MAPK12, ERK3, ERK6, P38GAMMA, PRKM12, SAPK-3, SAPK3	mitogen-activated protein kinase 12 (EC:2.7.11.24)	C00002731
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00002731
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002731
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002731
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002731
4176	MCM7, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146	minichromosome maintenance complex component 7 (EC:3.6.4.12)	C00002731
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00002731
4241	MFI2, CD228, MAP97, MTF1	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5	C00002731
4242	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222)	C00002731
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00002731
406938	MIR146A, MIRN146, MIRN146A, miR-146a, miRNA146A	microRNA 146a	C00002731
84981	MIR22HG, C17orf91	MIR22 host gene (non-protein coding)	C00002731
4288	MKI67, KIA, MIB-1	marker of proliferation Ki-67	C00002731
4311	MME, CALLA, CD10, NEP, SFE	membrane metallo-endopeptidase (EC:3.4.24.11)	C00002731
4319	MMP10, SL-2, STMY2	matrix metallopeptidase 10 (stromelysin 2) (EC:3.4.24.22)	C00002731
4322	MMP13, CLG3, MANDP1	matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-)	C00002731
4323	MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS	matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)	C00002731
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002731
4314	MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1	matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17)	C00002731
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00002731
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002731
10200	MPHOSPH6, MPP, MPP-6, MPP6	M-phase phosphoprotein 6	C00002731
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00002731
65008	MRPL1, BM022, L1MT, MRP-L1	mitochondrial ribosomal protein L1	C00002731
931	MS4A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7	membrane-spanning 4-domains, subfamily A, member 1	C00002731
4486	MST1R, CD136, CDw136, PTK8, RON	macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (EC:2.7.10.1)	C00002731
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00002731
4597	MVD, FP17780, MPD	mevalonate (diphospho) decarboxylase (EC:4.1.1.33)	C00002731
4084	MXD1, BHLHC58, MAD, MAD1	MAX dimerization protein 1	C00002731
83463	MXD3, BHLHC13, MAD3, MYX	MAX dimerization protein 3	C00002731
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002731
10627	MYL12A, MLCB, MRCL3, MRLC3, MYL2B	myosin, light chain 12A, regulatory, non-sarcomeric	C00002731
4638	MYLK, AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK	myosin light chain kinase (EC:2.7.11.18)	C00002731
4671	NAIP, BIRC1, NLRB1, psiNAIP	NLR family, apoptosis inhibitory protein	C00002731
340719	NANOS1, NOS1, SPGF12	nanos homolog 1 (Drosophila)	C00002731
79661	NEIL1, FPG1, NEI1, hFPG1	nei endonuclease VIII-like 1 (E. coli) (EC:4.2.99.18)	C00002731
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002731
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002731
4791	NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	C00002731
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00002731
4800	NFYA, CBF-A, CBF-B, HAP2, NF-YA	nuclear transcription factor Y, alpha	C00002731
374354	NHLRC2	NHL repeat containing 2	C00002731
4824	NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A	NK3 homeobox 1	C00002731
4830	NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1	NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6)	C00002731
64127	NOD2, ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1	nucleotide-binding oligomerization domain containing 2	C00002731
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00002731
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002731
4851	NOTCH1, TAN1, hN1	notch 1	C00002731
10577	NPC2, EDDM1, HE1	Niemann-Pick disease, type C2	C00002731
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00002731
10062	NR1H3, LXR-a, LXRA, RLD-1	nuclear receptor subfamily 1, group H, member 3	C00002731
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00002731
2908	NR3C1, GCCR, GCR, GR, GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	C00002731
4929	NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR	nuclear receptor subfamily 4, group A, member 2	C00002731
4928	NUP98, ADIR2, NUP196, NUP96	nucleoporin 98kDa	C00002731
4953	ODC1, ODC	ornithine decarboxylase 1 (EC:4.1.1.17)	C00002731
4968	OGG1, HMMH, HOGG1, MUTM, OGH1	8-oxoguanine DNA glycosylase (EC:4.2.99.18)	C00002731
56957	OTUD7B, CEZANNE, ZA20D1	OTU domain containing 7B (EC:3.4.19.12)	C00002731
5062	PAK2, PAK65, PAKgamma	p21 protein (Cdc42/Rac)-activated kinase 2 (EC:2.7.11.1)	C00002731
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002731
5105	PCK1, PEPCK-C, PEPCK1, PEPCKC	phosphoenolpyruvate carboxykinase 1 (soluble) (EC:4.1.1.32)	C00002731
5111	PCNA	proliferating cell nuclear antigen	C00002731
5159	PDGFRB, CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1	platelet-derived growth factor receptor, beta polypeptide (EC:2.7.10.1)	C00002731
5163	PDK1	pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2)	C00002731
5175	PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM	platelet/endothelial cell adhesion molecule 1	C00002731
8864	PER2, FASPS, FASPS1	period circadian clock 2	C00002731
5210	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (EC:2.7.1.105 3.1.3.46)	C00002731
5245	PHB, PHB1	prohibitin	C00002731
5328	PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA	plasminogen activator, urokinase (EC:3.4.21.73)	C00002731
5329	PLAUR, CD87, U-PAR, UPAR, URKR	plasminogen activator, urokinase receptor	C00002731
130271	PLEKHH2, PLEKHH1L	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2	C00002731
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00002731
56937	PMEPA1, STAG1, TMEPAI	prostate transmembrane protein, androgen induced 1	C00002731
5423	POLB	polymerase (DNA directed), beta (EC:2.7.7.7)	C00002731
10631	POSTN, OSF-2, OSF2, PDLPOSTN, PN, periostin	periostin, osteoblast specific factor	C00002731
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00002731
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00002731
79144	PPDPF, C20orf149, dJ697K14.9, exdpf	pancreatic progenitor cell differentiation and proliferation factor	C00002731
10105	PPIF, CYP3, CyP-M, Cyp-D, CypD	peptidylprolyl isomerase F (EC:5.2.1.8)	C00002731
5533	PPP3CC, CALNA3, CNA3, PP2Bgamma	protein phosphatase 3, catalytic subunit, gamma isozyme (EC:3.1.3.16)	C00002731
5562	PRKAA1, AMPK, AMPKa1	protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)	C00002731
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00002731
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00002731
5581	PRKCE, PKCE, nPKC-epsilon	protein kinase C, epsilon (EC:2.7.11.13)	C00002731
5583	PRKCH, PKC-L, PKCL, PRKCL, nPKC-eta	protein kinase C, eta (EC:2.7.11.13)	C00002731
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002731
5618	PRLR, hPRLrI	prolactin receptor	C00002731
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002731
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002731
5744	PTHLH, BDE2, HHM, PLP, PTHR, PTHRP	parathyroid hormone-like hormone	C00002731
5783	PTPN13, FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (EC:3.1.3.48)	C00002731
5777	PTPN6, HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1	protein tyrosine phosphatase, non-receptor type 6 (EC:3.1.3.48)	C00002731
5778	PTPN7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI	protein tyrosine phosphatase, non-receptor type 7 (EC:3.1.3.48)	C00002731
5801	PTPRR, EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ	protein tyrosine phosphatase, receptor type, R (EC:3.1.3.48)	C00002731
4218	RAB8A, MEL, RAB8	RAB8A, member RAS oncogene family	C00002731
5888	RAD51, BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA	RAD51 recombinase	C00002731
10267	RAMP1	receptor (G protein-coupled) activity modifying protein 1	C00002731
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00002731
9770	RASSF2, CENP-34, RASFADIN	Ras association (RalGDS/AF-6) domain family member 2	C00002731
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002731
9584	RBM39, CAPER, CAPERalpha, FSAP59, HCC1, RNPC2	RNA binding motif protein 39	C00002731
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002731
5980	REV3L, POLZ, REV3	REV3-like, polymerase (DNA directed), zeta, catalytic subunit (EC:2.7.7.7)	C00002731
5994	RFXAP	regulatory factor X-associated protein	C00002731
6004	RGS16, A28-RGS14, A28-RGS14P, RGS-R	regulator of G-protein signaling 16	C00002731
5999	RGS4, RGP4, SCZD9	regulator of G-protein signaling 4	C00002731
6000	RGS7	regulator of G-protein signaling 7	C00002731
9699	RIMS2, OBOE, RAB3IP3, RIM2	regulating synaptic membrane exocytosis 2	C00002731
6160	RPL31, L31	ribosomal protein L31	C00002731
6194	RPS6, S6	ribosomal protein S6	C00002731
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00002731
6242	RTKN	rhotekin	C00002731
860	RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA	runt-related transcription factor 2	C00002731
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00002731
90507	SCRN2, Ses2	secernin 2	C00002731
6389	SDHA, CMD1GG, FP, PGL5, SDH1, SDH2, SDHF	succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1)	C00002731
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00002731
989	SEPT7, CDC10, CDC3, NBLA02942, SEPT7A	septin 7	C00002731
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00002731
5268	SERPINB5, PI5, maspin	serpin peptidase inhibitor, clade B (ovalbumin), member 5	C00002731
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00002731
6421	SFPQ, POMP100, PSF	splicing factor proline/glutamine-rich	C00002731
6425	SFRP5, SARP3	secreted frizzled-related protein 5	C00002731
94081	SFXN1	sideroflexin 1	C00002731
7779	SLC30A1, ZNT1, ZRC1	solute carrier family 30 (zinc transporter), member 1	C00002731
2542	SLC37A4, G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d, TRG-19, TRG19	solute carrier family 37 (glucose-6-phosphate transporter), member 4	C00002731
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00002731
55652	SLC48A1, HRG-1, HRG1, hHRG-1	solute carrier family 48 (heme transporter), member 1	C00002731
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00002731
6579	SLCO1A2, OATP, OATP-A, OATP1A2, SLC21A3	solute carrier organic anion transporter family, member 1A2	C00002731
6607	SMN2, BCD541, C-BCD541, GEMIN1, SMNC, TDRD16B	survival of motor neuron 2, centromeric	C00002731
6591	SNAI2, SLUG, SLUGH1, SNAIL2, WS2D	snail family zinc finger 2	C00002731
85028	SNHG12, C1orf79, LINC00100, NCRNA00100, RP4-669K10.5	small nucleolar RNA host gene 12 (non-protein coding)	C00002731
6662	SOX9, CMD1, CMPD1, SRA1	SRY (sex determining region Y)-box 9	C00002731
6667	SP1	Sp1 transcription factor	C00002731
6670	SP3, SPR2	Sp3 transcription factor	C00002731
6671	SP4, HF1B, SPR-1	Sp4 transcription factor	C00002731
6689	SPIB, SPI-B	Spi-B transcription factor (Spi-1/PU.1 related)	C00002731
6695	SPOCK1, SPOCK, TESTICAN, TIC1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	C00002731
6714	SRC, ASV, SRC1, c-SRC, p60-Src	v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC:2.7.10.2)	C00002731
6426	SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a	serine/arginine-rich splicing factor 1	C00002731
6427	SRSF2, PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b	serine/arginine-rich splicing factor 2	C00002731
6428	SRSF3, SFRS3, SRp20	serine/arginine-rich splicing factor 3	C00002731
6430	SRSF5, HRS, SFRS5, SRP40	serine/arginine-rich splicing factor 5	C00002731
6431	SRSF6, B52, SFRS6, SRP55	serine/arginine-rich splicing factor 6	C00002731
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00002731
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00002731
6775	STAT4, SLEB11	signal transducer and activator of transcription 4	C00002731
6776	STAT5A, MGF, STAT5	signal transducer and activator of transcription 5A	C00002731
6777	STAT5B, STAT5	signal transducer and activator of transcription 5B	C00002731
412	STS, ARSC, ARSC1, ASC, ES, SSDD, XLI	steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2)	C00002731
23213	SULF1, HSULF-1, SULF-1	sulfatase 1	C00002731
23512	SUZ12, CHET9, JJAZ1	SUZ12 polycomb repressive complex 2 subunit	C00002731
10388	SYCP2, SCP2	synaptonemal complex protein 2	C00002731
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00002731
11138	TBC1D8, AD3, HBLP1, TBC1D8A, VRP	TBC1 domain family, member 8 (with GRAM domain)	C00002731
6934	TCF7L2, TCF-4, TCF4	transcription factor 7-like 2 (T-cell specific, HMG-box)	C00002731
7015	TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT	telomerase reverse transcriptase (EC:2.7.7.49)	C00002731
7018	TF, PRO1557, PRO2086, TFQTL1	transferrin	C00002731
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00002731
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00002731
9220	TIAF1, MAJN, SPR210	TGFB1-induced anti-apoptotic factor 1	C00002731
7076	TIMP1, CLGI, EPA, EPO, HCI, TIMP	TIMP metallopeptidase inhibitor 1	C00002731
7077	TIMP2, CSC-21K, DDC8	TIMP metallopeptidase inhibitor 2	C00002731
7113	TMPRSS2, PP9284, PRSS10	transmembrane protease, serine 2 (EC:3.4.21.-)	C00002731
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002731
8797	TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1	tumor necrosis factor receptor superfamily, member 10a	C00002731
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00002731
7132	TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60	tumor necrosis factor receptor superfamily, member 1A	C00002731
7133	TNFRSF1B, CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR	tumor necrosis factor receptor superfamily, member 1B	C00002731
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00002731
8600	TNFSF11, CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf	tumor necrosis factor (ligand) superfamily, member 11	C00002731
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00002731
7155	TOP2B, TOPIIB, top2beta	topoisomerase (DNA) II beta 180kDa (EC:5.99.1.3)	C00002731
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002731
8717	TRADD, Hs.89862	TNFRSF1A-associated via death domain	C00002731
7185	TRAF1, EBI6, MGC:10353	TNF receptor-associated factor 1	C00002731
7186	TRAF2, MGC:45012, TRAP, TRAP3	TNF receptor-associated factor 2	C00002731
7187	TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1	TNF receptor-associated factor 3	C00002731
7189	TRAF6, MGC:3310, RNF85	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	C00002731
54210	TREM1, CD354, TREM-1	triggering receptor expressed on myeloid cells 1	C00002731
57761	TRIB3, C20orf97, NIPK, SINK, SKIP3, TRB3	tribbles pseudokinase 3	C00002731
10626	TRIM16, EBBP	tripartite motif containing 16	C00002731
7249	TSC2, LAM, TSC4	tuberous sclerosis 2	C00002731
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00002731
1890	TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF	thymidine phosphorylase (EC:2.4.2.4)	C00002731
7316	UBC, HMG20	ubiquitin C	C00002731
11065	UBE2C, UBCH10, dJ447F3.2	ubiquitin-conjugating enzyme E2C (EC:6.3.2.19)	C00002731
7361			C00002731
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002731
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002731
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00002731
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002731
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002731
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002731
10813	UTP14A, NYCO16, SDCCAG16, dJ537K23.3	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	C00002731
7408	VASP	vasodilator-stimulated phosphoprotein	C00002731
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00002731
7428	VHL, HRCA1, RCA1, VHL1, pVHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	C00002731
7432	VIP, PHM27	vasoactive intestinal peptide	C00002731
7490	WT1, AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33	Wilms tumor 1	C00002731
54739	XAF1, BIRC4BP, HSXIAPAF1, XIAPAF1	XIAP associated factor 1	C00002731
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00002731
7515	XRCC1, RCC	X-ray repair complementing defective repair in Chinese hamster cells 1	C00002731
7518	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	C00002731
7520	XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	C00002731
2547	XRCC6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA	X-ray repair complementing defective repair in Chinese hamster cells 6	C00002731
83719	YPEL3	yippee-like 3 (Drosophila)	C00002731
7531	YWHAE, 14-3-3E, KCIP-1, MDCR, MDS	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	C00002731
463	ZFHX3, ATBF1, ATBT, ZNF927	zinc finger homeobox 3	C00002731
677	ZFP36L1, BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1	ZFP36 ring finger protein-like 1	C00002731
57336	ZNF287, ZKSCAN13, ZSCAN45	zinc finger protein 287	C00002731
51385	ZNF589, SZF1	zinc finger protein 589	C00002731
55552	ZNF823, HSZFP36	zinc finger protein 823	C00002731

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