Metabolite

KNApSAcK Entry

id C00002731
Name Curcumin
CAS RN 458-37-7
Standard InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-13,22,24-25H,1-2H3/b7-3+,8-4+,16-13-
Standard InChI (Main Layer) InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-13,22,24-25H,1-2H3

Cluster

Phytochemical cluster No. 31
KCF-S cluster No. 3613

Link

ChEMBL

By standard InChI CHEMBL116438
By standard InChI Main Layer CHEMBL116438

KEGG

By LinkDB C10443

CTD

By CAS RN D003474

Human Protein / Gene in interaction

91 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL116438 CHEMBL999391 (1)
1 / 0
P33527 Multidrug resistance-associated protein 1 drugs CHEMBL116438 CHEMBL2078146 (1)
0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr CHEMBL116438 CHEMBL898096 (1)
0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL116438 CHEMBL1613995 (1) CHEMBL1738132 (1)
7 / 44
Q09472 Histone acetyltransferase p300 Enzyme CHEMBL116438 CHEMBL904249 (1) CHEMBL904262 (1)
CHEMBL904261 (1) CHEMBL1025548 (1)
1 / 1
Q9NR96 Toll-like receptor 9 Toll-like and Il-1 receptors CHEMBL116438 CHEMBL1794460 (1)
0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL116438 CHEMBL1738312 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL116438 CHEMBL2114784 (1)
1 / 1
P09917 Arachidonate 5-lipoxygenase Oxidoreductase CHEMBL116438 CHEMBL937179 (1)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL116438 CHEMBL825457 (1) CHEMBL1008495 (1)
CHEMBL1686537 (1) CHEMBL1686539 (1)
0 / 3
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL116438 CHEMBL1227478 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL116438 CHEMBL1227477 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL116438 CHEMBL1227480 (1)
0 / 0
Q05655 Protein kinase C delta type Delta CHEMBL116438 CHEMBL1072759 (1)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL116438 CHEMBL982420 (1)
2 / 2
Q04759 Protein kinase C theta type Delta CHEMBL116438 CHEMBL1072761 (1)
0 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL116438 CHEMBL1794585 (1)
0 / 0
Q8N1Q1 Carbonic anhydrase 13 Lyase CHEMBL116438 CHEMBL1227626 (1)
0 / 0
P20813 Cytochrome P450 2B6 Cytochrome P450 2B6 CHEMBL116438 CHEMBL999392 (1)
1 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme CHEMBL116438 CHEMBL1614331 (1)
0 / 0
P37840 Alpha-synuclein Unclassified protein CHEMBL116438 CHEMBL2354282 (1)
4 / 2
P00918 Carbonic anhydrase 2 Lyase CHEMBL116438 CHEMBL1227474 (1)
1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL116438 CHEMBL1738166 (1) CHEMBL1794335 (1)
0 / 1
Q02156 Protein kinase C epsilon type Eta CHEMBL116438 CHEMBL1072760 (1)
0 / 0
P08183 Multidrug resistance protein 1 drug CHEMBL116438 CHEMBL2075627 (1) CHEMBL2077298 (1)
CHEMBL2077431 (1)
1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL116438 CHEMBL999390 (1)
0 / 1
P30291 Wee1-like protein kinase WEE serine/threonine protein kinase subfamily CHEMBL116438 CHEMBL1166287 (1)
0 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL116438 CHEMBL1613808 (1) CHEMBL2040215 (1)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL116438 CHEMBL2040215 (1)
0 / 0
Q9UBC3 DNA (cytosine-5)-methyltransferase 3B Enzyme CHEMBL116438 CHEMBL1072865 (1)
1 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL116438 CHEMBL2318907 (1)
1 / 11
P11387 DNA topoisomerase 1 Isomerase CHEMBL116438 CHEMBL927384 (1) CHEMBL927386 (1)
0 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL116438 CHEMBL1794311 (3) CHEMBL2329675 (1)
CHEMBL2329676 (1) CHEMBL2329678 (1)
CHEMBL2329680 (1) CHEMBL2329681 (1)
2 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL116438 CHEMBL937180 (1) CHEMBL1008496 (1)
CHEMBL1686536 (1) CHEMBL1686538 (1)
0 / 0
P23280 Carbonic anhydrase 6 Lyase CHEMBL116438 CHEMBL1227479 (1)
0 / 0
P05067 Amyloid beta A4 protein Membrane receptor CHEMBL116438 CHEMBL907197 (1) CHEMBL983535 (1)
CHEMBL1252224 (1) CHEMBL1252227 (1)
2 / 2
O15296 Arachidonate 15-lipoxygenase B Enzyme CHEMBL116438 CHEMBL1613800 (1)
0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL116438 CHEMBL1227627 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL116438 CHEMBL1614458 (1)
0 / 0
P68871 Hemoglobin subunit beta Secreted protein CHEMBL116438 CHEMBL1614204 (1) CHEMBL1613976 (1)
4 / 4
O43570 Carbonic anhydrase 12 Lyase CHEMBL116438 CHEMBL1227625 (1)
1 / 2
Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha Camk2 CHEMBL116438 CHEMBL2148927 (1) CHEMBL2148929 (1)
CHEMBL2148930 (1) CHEMBL2148931 (1)
CHEMBL2148932 (1) CHEMBL2148933 (2)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL116438 CHEMBL1794486 (1)
0 / 0
Q92993 Histone acetyltransferase KAT5 Enzyme CHEMBL116438 CHEMBL1025546 (1)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL116438 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL116438 CHEMBL2114843 (2) CHEMBL2114780 (2)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL116438 CHEMBL1227473 (1)
0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor CHEMBL116438 CHEMBL2339282 (1) CHEMBL2344706 (1)
CHEMBL2345133 (1) CHEMBL2353055 (1)
CHEMBL2353059 (1) CHEMBL2353060 (1)
1 / 2
P09923 Intestinal-type alkaline phosphatase Enzyme CHEMBL116438 CHEMBL1738679 (1) CHEMBL1738192 (1)
0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme CHEMBL116438 CHEMBL1738602 (1)
3 / 1
P11308 Transcriptional regulator ERG Unclassified protein CHEMBL116438 CHEMBL2114924 (1)
1 / 2
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL116438 CHEMBL1614257 (3) CHEMBL1614410 (1)
CHEMBL1614531 (3)
1 / 3
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL116438 CHEMBL1963863 (1)
0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL116438 CHEMBL1794467 (2)
0 / 0
Q99816 Tumor susceptibility gene 101 protein Unclassified protein CHEMBL116438 CHEMBL1738574 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL116438 CHEMBL2329674 (1)
0 / 1
P14679 Tyrosinase Oxidoreductase CHEMBL116438 CHEMBL1054042 (1)
4 / 2
P06276 Cholinesterase Hydrolase CHEMBL116438 CHEMBL1771989 (1)
0 / 0
P45452 Collagenase 3 M10A CHEMBL116438 CHEMBL963566 (1)
1 / 1
P13726 Tissue factor Membrane receptor CHEMBL116438 CHEMBL2319887 (1)
0 / 0
P37058 Testosterone 17-beta-dehydrogenase 3 Enzyme CHEMBL116438 CHEMBL1108828 (1) CHEMBL1108830 (1)
1 / 1
P10696 Alkaline phosphatase, placental-like Enzyme CHEMBL116438 CHEMBL1738040 (1)
0 / 1
P56817 Beta-secretase 1 A1A CHEMBL116438 CHEMBL2162067 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL116438 CHEMBL999388 (1)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL116438 CHEMBL1228226 (1)
0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL116438 CHEMBL1613910 (1)
3 / 3
Q99873 Protein arginine N-methyltransferase 1 Enzyme CHEMBL116438 CHEMBL919884 (1)
0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL116438 CHEMBL1614038 (1)
2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL116438 CHEMBL1738588 (1)
0 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL116438 CHEMBL1771988 (1)
1 / 0
P26358 DNA (cytosine-5)-methyltransferase 1 Transferase CHEMBL116438 CHEMBL1035628 (1) CHEMBL1072864 (1)
2 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL116438 CHEMBL1614240 (1)
0 / 0
P35228 Nitric oxide synthase, inducible Enzyme CHEMBL116438 CHEMBL937658 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL116438 CHEMBL999389 (1) CHEMBL1614108 (1)
CHEMBL1613886 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL116438 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL116438 CHEMBL1737991 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL116438 CHEMBL1614421 (2) CHEMBL1614502 (2)
4 / 3
P10997 Islet amyloid polypeptide Unclassified protein CHEMBL116438 CHEMBL2182533 (1) CHEMBL2182534 (1)
CHEMBL2182535 (1) CHEMBL2182536 (1)
CHEMBL2182537 (1) CHEMBL2182539 (1)
CHEMBL2182540 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL116438 CHEMBL2114908 (1)
0 / 0
P05412 Transcription factor AP-1 Transcription Factor CHEMBL116438 CHEMBL1787461 (1)
0 / 0
P07451 Carbonic anhydrase 3 Lyase CHEMBL116438 CHEMBL1227475 (1)
0 / 0
Q04760 Lactoylglutathione lyase Enzyme CHEMBL116438 CHEMBL1670272 (1) CHEMBL1799085 (1)
0 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL116438 CHEMBL1227476 (1)
1 / 1
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL116438 CHEMBL1794536 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL116438 CHEMBL1613914 (2)
0 / 0
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein CHEMBL116438 CHEMBL2344705 (1) CHEMBL2353062 (1)
3 / 3
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL116438 CHEMBL1614364 (1)
1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL116438 CHEMBL2354311 (1)
1 / 0
O00255 Menin Unclassified protein CHEMBL116438 CHEMBL1614257 (3) CHEMBL1614531 (3)
2 / 5
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL116438 CHEMBL2114738 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL116438 CHEMBL2354287 (1)
1 / 1

CTD interaction (1257)

compound gene gene name gene description interaction interaction type form reference
pmid
D003474 53947 A4GALT
A14GALT
A4GALT1
Gb3S
P(k)
P1
P1PK
PK
alpha 1,4-galactosyltransferase (EC:2.4.1.228) Curcumin inhibits the reaction [IL1B protein results in increased expression of A4GALT mRNA] decreases reaction
/ increases expression
mRNA 16819191
D003474 53947 A4GALT
A14GALT
A4GALT1
Gb3S
P(k)
P1
P1PK
PK
alpha 1,4-galactosyltransferase (EC:2.4.1.228) Curcumin inhibits the reaction [TNF protein results in increased expression of A4GALT mRNA] decreases reaction
/ increases expression
mRNA 16819191
D003474 16 AARS
CMT2N
alanyl-tRNA synthetase (EC:6.1.1.7) Curcumin results in decreased expression of AARS mRNA decreases expression
mRNA 17198877
D003474 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) ABCB1 affects the susceptibility to Curcumin affects response to substance
15476675
D003474 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) Curcumin results in decreased expression of ABCB1 mRNA decreases expression
mRNA 17121181
18414057
18439772
D003474 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) Curcumin results in decreased expression of and results in decreased activity of ABCB1 protein decreases activity
/ decreases expression
protein 18439772
D003474 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) [sulfinosine co-treated with Curcumin] results in decreased expression of ABCB1 mRNA affects cotreatment
/ decreases expression
mRNA 18414057
D003474 18669 Curcumin results in decreased expression of ABCB1B mRNA decreases expression
mRNA 20816778
D003474 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Curcumin results in decreased activity of ABCC1 protein decreases activity
protein 15885658
16021489
D003474 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Curcumin results in decreased activity of ABCC2 protein decreases activity
protein 15885658
D003474 9619 ABCG1
ABC8
WHITE1
ATP-binding cassette, sub-family G (WHITE), member 1 Curcumin results in increased expression of ABCG1 mRNA increases expression
mRNA 16713233
21594647
D003474 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein] increases expression
/ increases reaction
protein 17077187
D003474 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 Curcumin results in increased expression of ABCG2 protein increases expression
protein 17077187
D003474 31 ACACA
ACAC
ACACAD
ACC
ACC1
ACCA
acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14) Curcumin results in increased phosphorylation of ACACA protein increases phosphorylation
protein 18790744
D003474 57007 ACKR3
CMKOR1
CXC-R7
CXCR-7
CXCR7
GPR159
RDC-1
RDC1
atypical chemokine receptor 3 Curcumin results in increased expression of ACKR3 mRNA increases expression
mRNA 21594647
D003474 6868 ADAM17
ADAM18
CD156B
CSVP
NISBD
TACE
ADAM metallopeptidase domain 17 (EC:3.4.24.86) Curcumin inhibits the reaction [TNF protein results in increased expression of ADAM17 mRNA] decreases reaction
/ increases expression
mRNA 17666914
D003474 9507 ADAMTS4
ADAMTS-2
ADAMTS-4
ADMP-1
ADAM metallopeptidase with thrombospondin type 1 motif, 4 (EC:3.4.24.82) Curcumin results in increased expression of ADAMTS4 mRNA increases expression
mRNA 18321735
D003474 115 ADCY9
AC9
adenylate cyclase 9 (EC:4.6.1.1) Curcumin results in decreased expression of ADCY9 mRNA decreases expression
mRNA 15713895
D003474 10551 AGR2
AG2
GOB-4
HAG-2
PDIA17
XAG-2
anterior gradient 2 Curcumin results in decreased expression of AGR2 mRNA decreases expression
mRNA 17198877
D003474 196 AHR
bHLHe76
aryl hydrocarbon receptor AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein] increases expression
/ increases reaction
protein 17077187
D003474 196 AHR
bHLHe76
aryl hydrocarbon receptor Curcumin results in increased degradation of AHR protein increases degradation
protein 19018768
D003474 9472 AKAP6
ADAP100
ADAP6
AKAP100
PRKA6
mAKAP
A kinase (PRKA) anchor protein 6 Curcumin results in increased expression of AKAP6 mRNA increases expression
mRNA 18421014
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased phosphorylation of AKT1 protein] decreases reaction
/ increases phosphorylation
protein 20938987
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) arsenic trioxide promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] decreases phosphorylation
/ increases reaction
protein 20605902
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] decreases phosphorylation
/ decreases reaction
protein 18790744
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein] decreases reaction
/ increases phosphorylation
protein 18660423
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein] decreases reaction
/ increases phosphorylation
protein 18214481
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of AKT1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 17291458
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin inhibits the reaction [Nicotine results in increased expression of AKT1 protein modified form] decreases reaction
/ increases expression
protein 20727180
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 16219905
17640567
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein] decreases activity
/ decreases expression
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin results in decreased activity of AKT1 protein decreases activity
protein 16023083
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein decreases activity
/ decreases expression
/ decreases phosphorylation
protein 17918158
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin results in decreased phosphorylation of AKT1 protein decreases phosphorylation
protein 17289836
17332930
17596214
18790744
19372569
20605902
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin results in increased expression of AKT1 protein increases expression
protein 23222814
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Curcumin results in increased phosphorylation of AKT1 protein increases phosphorylation
protein 20938987
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]] decreases reaction
/ increases activity
/ increases phosphorylation
protein 17640567
D003474 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) lonidamine promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] decreases phosphorylation
/ increases reaction
protein 20605902
D003474 226 ALDOA
ALDA
GSD12
aldolase A, fructose-bisphosphate (EC:4.1.2.13) Curcumin results in decreased expression of ALDOA mRNA decreases expression
mRNA 16880289
D003474 230 ALDOC
ALDC
aldolase C, fructose-bisphosphate (EC:4.1.2.13) Curcumin results in decreased expression of ALDOC mRNA decreases expression
mRNA 17198877
D003474 353322 ANKRD37
Lrp2bp
ankyrin repeat domain 37 Curcumin results in decreased expression of ANKRD37 mRNA decreases expression
mRNA 17198877
D003474 57182 ANKRD50
ankyrin repeat domain 50 Curcumin results in decreased expression of ANKRD50 mRNA decreases expression
mRNA 17999991
D003474 55139 ANKZF1
ZNF744
ankyrin repeat and zinc finger domain containing 1 Curcumin results in decreased expression of ANKZF1 mRNA decreases expression
mRNA 17198877
D003474 324 APC
BTPS2
DP2
DP2.5
DP3
GS
PPP1R46
adenomatous polyposis coli Curcumin results in decreased expression of APC mRNA decreases expression
mRNA 15713895
D003474 351 APP
AAA
ABETA
ABPP
AD1
APPI
CTFgamma
CVAP
PN-II
PN2
amyloid beta (A4) precursor protein Curcumin affects the reaction [APP protein binds to APP protein] affects binding
/ affects reaction
protein 18537544
D003474 351 APP
AAA
ABETA
ABPP
AD1
APPI
CTFgamma
CVAP
PN-II
PN2
amyloid beta (A4) precursor protein Curcumin inhibits the reaction [Copper results in increased expression of APP mRNA] decreases reaction
/ increases expression
mRNA 18583042
D003474 360 AQP3
AQP-3
GIL
aquaporin 3 (Gill blood group) Curcumin inhibits the reaction [EGF protein results in increased expression of AQP3 protein] decreases reaction
/ increases expression
protein 18214481
D003474 360 AQP3
AQP-3
GIL
aquaporin 3 (Gill blood group) Curcumin results in decreased expression of AQP3 protein decreases expression
protein 18214481
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin inhibits the reaction [AR protein results in increased expression of KLK3 mRNA] decreases reaction
/ increases expression
protein 22258452
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to TMPRSS2 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin inhibits the reaction [IL6 protein results in increased expression of AR mRNA] decreases reaction
/ increases expression
mRNA 18676361
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin inhibits the reaction [IL6 protein results in increased expression of AR protein] decreases reaction
/ increases expression
protein 18676361
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin results in decreased activity of AR protein decreases activity
protein 22258452
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin results in decreased expression of AR mRNA decreases expression
mRNA 18676361
18719366
D003474 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Curcumin results in decreased expression of AR protein decreases expression
protein 12497104
18719366
D003474 257106 ARHGAP30
Rho GTPase activating protein 30 Curcumin results in decreased expression of ARHGAP30 mRNA decreases expression
mRNA 18421014
D003474 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator Acetylcysteine inhibits the reaction [Curcumin results in increased degradation of ARNT protein] decreases reaction
/ increases degradation
protein 16880289
D003474 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in increased degradation of ARNT protein] decreases reaction
/ increases degradation
protein 16880289
D003474 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator Curcumin results in decreased expression of ARNT protein decreases expression
protein 18682687
D003474 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator Curcumin results in increased degradation of ARNT protein increases degradation
protein 19018768
D003474 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator Curcumin results in increased ubiquitination of and results in increased degradation of ARNT protein increases degradation
/ increases ubiquitination
protein 16880289
D003474 467 ATF3
activating transcription factor 3 Curcumin results in increased expression of ATF3 mRNA increases expression
mRNA 15713895
18719366
D003474 467 ATF3
activating transcription factor 3 Curcumin results in increased expression of ATF3 protein increases expression
protein 15713895
18555241
D003474 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) Curcumin results in increased phosphorylation of ATM protein increases phosphorylation
protein 19401701
21134073
D003474 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) [Isoflavones co-treated with Curcumin] results in increased phosphorylation of ATM protein affects cotreatment
/ increases phosphorylation
protein 21134073
D003474 126792 B3GALT6
EDSP2
SEMDJL1
beta3GalT6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 (EC:2.4.1.134) Curcumin results in increased expression of B3GALT6 mRNA increases expression
mRNA 17198877
D003474 23621 BACE1
ASP2
BACE
HSPC104
beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) Curcumin inhibits the reaction [Copper results in increased expression of BACE1 mRNA] decreases reaction
/ increases expression
mRNA 18583042
D003474 572 BAD
BBC2
BCL2L8
BCL2-associated agonist of cell death Curcumin results in increased expression of BAD mRNA increases expression
mRNA 19235267
D003474 572 BAD
BBC2
BCL2L8
BCL2-associated agonist of cell death Curcumin results in increased expression of BAD protein increases expression
protein 19235267
D003474 578 BAK1
BAK
BAK-LIKE
BCL2L7
CDN1
BCL2-antagonist/killer 1 Curcumin results in increased expression of BAK1 mRNA increases expression
mRNA 17332930
D003474 578 BAK1
BAK
BAK-LIKE
BCL2L7
CDN1
BCL2-antagonist/killer 1 Curcumin results in increased expression of BAK1 protein increases expression
protein 17332930
18226269
D003474 578 BAK1
BAK
BAK-LIKE
BCL2L7
CDN1
BCL2-antagonist/killer 1 TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAK1 protein] increases expression
/ increases reaction
protein 18226269
D003474 581 BAX
BCL2L4
BCL2-associated X protein arsenic trioxide promotes the reaction [Curcumin affects the localization of BAX protein] affects localization
/ increases reaction
protein 20605902
D003474 581 BAX
BCL2L4
BCL2-associated X protein Curcumin affects the localization of BAX protein affects localization
protein 17332930
20605902
D003474 581 BAX
BCL2L4
BCL2-associated X protein [Curcumin co-treated with Sirolimus] results in increased expression of BAX affects cotreatment
/ increases expression
19373661
D003474 581 BAX
BCL2L4
BCL2-associated X protein Curcumin inhibits the reaction [bisphenol A results in decreased expression of BAX protein] decreases expression
/ decreases reaction
protein 23222814
D003474 581 BAX
BCL2L4
BCL2-associated X protein Curcumin promotes the reaction [arsenic trioxide affects the localization of BAX protein] affects localization
/ increases reaction
protein 20605902
D003474 581 BAX
BCL2L4
BCL2-associated X protein Curcumin promotes the reaction [lonidamine affects the localization of BAX protein] affects localization
/ increases reaction
protein 20605902
D003474 581 BAX
BCL2L4
BCL2-associated X protein Curcumin results in increased expression of BAX mRNA increases expression
mRNA 17332930
17671742
19235267
D003474 581 BAX
BCL2L4
BCL2-associated X protein Curcumin results in increased expression of BAX protein increases expression
protein 17096185
17332930
17671742
18226269
19235267
21594647
23222814
D003474 581 BAX
BCL2L4
BCL2-associated X protein lonidamine promotes the reaction [Curcumin affects the localization of BAX protein] affects localization
/ increases reaction
protein 20605902
D003474 581 BAX
BCL2L4
BCL2-associated X protein TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAX protein] increases expression
/ increases reaction
protein 18226269
D003474 27113 BBC3
JFY-1
JFY1
PUMA
BCL2 binding component 3 Curcumin results in increased expression of BBC3 mRNA increases expression
mRNA 17332930
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin analog results in decreased expression of BCL2 mRNA decreases expression
mRNA 17671737
19250217
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Curcumin co-treated with Isoflavones] results in decreased expression of BCL2 protein affects cotreatment
/ decreases expression
protein 18640131
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Curcumin co-treated with Sirolimus] results in decreased expression of BCL2 affects cotreatment
/ decreases expression
19373661
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin inhibits the reaction [docetaxel results in increased phosphorylation of BCL2 protein] decreases reaction
/ increases phosphorylation
protein 14724571
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin inhibits the reaction [Nicotine results in increased expression of BCL2 protein] decreases reaction
/ increases expression
protein 20727180
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin inhibits the reaction [Paclitaxel results in increased expression of BCL2 protein] decreases reaction
/ increases expression
protein 16243823
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA] decreases reaction
/ increases expression
mRNA 16219905
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein] decreases reaction
/ increases expression
protein 17640567
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin results in decreased expression of BCL2 mRNA decreases expression
mRNA 17332930
17596214
17671737
17671742
19235267
19250217
21595920
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Curcumin results in decreased expression of BCL2 protein decreases expression
protein 12497104
16023083
17096185
17332930
17671742
18226269
18593936
19235267
19372569
21595920
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Curcumin results in increased expression of SERPINB5] which results in decreased expression of BCL2 protein decreases expression
/ increases expression
protein 19944674
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]] decreases reaction
/ increases expression
protein 17640567
D003474 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2 protein] decreases expression
/ increases reaction
protein 18226269
D003474 597 BCL2A1
ACC-1
ACC-2
BCL2L5
BFL1
GRS
HBPA1
BCL2-related protein A1 Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2A1 mRNA] decreases reaction
/ increases expression
mRNA 16219905
D003474 597 BCL2A1
ACC-1
ACC-2
BCL2L5
BFL1
GRS
HBPA1
BCL2-related protein A1 Curcumin results in decreased expression of BCL2A1 mRNA decreases expression
mRNA 17596214
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Curcumin analog results in decreased expression of BCL2L1 mRNA decreases expression
mRNA 17671737
19250217
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 [Curcumin co-treated with Doxorubicin] affects the expression of BCL2L1 mRNA affects cotreatment
/ affects expression
mRNA 15911101
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 [Curcumin co-treated with Isoflavones] results in decreased expression of BCL2L1 protein affects cotreatment
/ decreases expression
protein 18640131
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Curcumin inhibits the reaction [Paclitaxel results in increased expression of BCL2L1 protein] decreases reaction
/ increases expression
protein 16243823
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA] decreases reaction
/ increases expression
mRNA 16219905
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein] decreases reaction
/ increases expression
protein 17640567
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Curcumin results in decreased expression of BCL2L1 mRNA decreases expression
mRNA 15911101
17596214
19235267
19250217
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Curcumin results in decreased expression of BCL2L1 protein decreases expression
protein 12497104
16023083
16173963
17148446
17332930
18226269
19235267
19372569
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Curcumin results in increased expression of BCL2L1 mRNA increases expression
mRNA 15911101
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]] decreases reaction
/ increases expression
protein 17640567
D003474 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2L1 protein] decreases expression
/ increases reaction
protein 18226269
D003474 10018 BCL2L11
BAM
BIM
BOD
BCL2-like 11 (apoptosis facilitator) Curcumin results in increased expression of BCL2L11 mRNA increases expression
mRNA 17332930
D003474 599 BCL2L2
BCL-W
BCL2-L-2
BCLW
PPP1R51
BCL2-like 2 Curcumin results in increased expression of BCL2L2 mRNA increases expression
mRNA 16101141
D003474 54880 BCOR
ANOP2
MAA2
MCOPS2
BCL6 corepressor Curcumin results in increased expression of BCOR mRNA increases expression
mRNA 17198877
D003474 637 BID
FP497
BH3 interacting domain death agonist Curcumin promotes the reaction [arsenic trioxide results in increased activity of BID protein] increases activity
/ increases reaction
protein 20605902
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Curcumin analog results in decreased expression of BIRC2 mRNA decreases expression
mRNA 17671737
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Curcumin inhibits the reaction [Nicotine results in increased expression of BIRC2 protein] decreases reaction
/ increases expression
protein 20727180
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC2 protein] decreases reaction
/ increases expression
protein 16243823
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA] decreases reaction
/ increases expression
mRNA 16219905
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein] decreases reaction
/ increases expression
protein 17640567
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Curcumin results in decreased expression of BIRC2 mRNA decreases expression
mRNA 17596214
17671737
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Curcumin results in decreased expression of BIRC2 protein decreases expression
protein 16023083
D003474 329 BIRC2
API1
HIAP2
Hiap-2
MIHB
RNF48
c-IAP1
cIAP1
baculoviral IAP repeat containing 2 Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]] decreases reaction
/ increases expression
protein 17640567
D003474 330 BIRC3
AIP1
API2
CIAP2
HAIP1
HIAP1
MALT2
MIHC
RNF49
c-IAP2
baculoviral IAP repeat containing 3 [Curcumin co-treated with Doxorubicin] affects the expression of BIRC3 mRNA affects cotreatment
/ affects expression
mRNA 15911101
D003474 330 BIRC3
AIP1
API2
CIAP2
HAIP1
HIAP1
MALT2
MIHC
RNF49
c-IAP2
baculoviral IAP repeat containing 3 Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC3 protein] decreases reaction
/ increases expression
protein 16243823
D003474 330 BIRC3
AIP1
API2
CIAP2
HAIP1
HIAP1
MALT2
MIHC
RNF49
c-IAP2
baculoviral IAP repeat containing 3 Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA] decreases reaction
/ increases expression
mRNA 16219905
D003474 330 BIRC3
AIP1
API2
CIAP2
HAIP1
HIAP1
MALT2
MIHC
RNF49
c-IAP2
baculoviral IAP repeat containing 3 Curcumin results in decreased expression of BIRC3 mRNA decreases expression
mRNA 17596214
D003474 330 BIRC3
AIP1
API2
CIAP2
HAIP1
HIAP1
MALT2
MIHC
RNF49
c-IAP2
baculoviral IAP repeat containing 3 Curcumin results in decreased expression of BIRC3 protein decreases expression
protein 19372569
D003474 330 BIRC3
AIP1
API2
CIAP2
HAIP1
HIAP1
MALT2
MIHC
RNF49
c-IAP2
baculoviral IAP repeat containing 3 Curcumin results in increased expression of BIRC3 mRNA increases expression
mRNA 15911101
16101141
D003474 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 Curcumin analog results in decreased expression of BIRC5 mRNA decreases expression
mRNA 17671737
D003474 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 Curcumin inhibits the reaction [Nicotine results in increased expression of BIRC5 protein] decreases reaction
/ increases expression
protein 20727180
D003474 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 Curcumin results in decreased expression of BIRC5 mRNA decreases expression
mRNA 17596214
17671737
19235267
D003474 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 Curcumin results in decreased expression of BIRC5 protein decreases expression
protein 16023083
18593936
19235267
19372569
D003474 79444 BIRC7
KIAP
LIVIN
ML-IAP
MLIAP
RNF50
baculoviral IAP repeat containing 7 Curcumin results in increased expression of BIRC7 mRNA increases expression
mRNA 15911101
D003474 834 CASP1
ICE
IL1BC
P45
caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) Curcumin results in increased expression of CASP1 mRNA increases expression
mRNA 16101141
D003474 835 CASP2
CASP-2
ICH1
NEDD-2
NEDD2
PPP1R57
caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55) Curcumin results in increased expression of CASP2 mRNA increases expression
mRNA 16101141
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Acetylcysteine inhibits the reaction [Curcumin results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 17332930
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin analog results in increased activity of CASP3 protein increases activity
protein 17041101
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin analog results in increased cleavage of CASP3 protein increases cleavage
protein 20599780
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Curcumin co-treated with arsenic trioxide] results in increased cleavage of CASP3 protein affects cotreatment
/ increases cleavage
protein 20605902
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Curcumin co-treated with lonidamine] results in increased cleavage of CASP3 protein affects cotreatment
/ increases cleavage
protein 20605902
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Curcumin co-treated with Sirolimus] results in increased activity of CASP3 protein affects cotreatment
/ increases activity
protein 19373661
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in decreased activity of CASP3 protein decreases activity
protein 15095415
21450334
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in decreased expression of CASP3 protein decreases expression
protein 17148446
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in increased activity of CASP3 increases activity
21595920
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in increased activity of CASP3 protein increases activity
protein 17041101
17096185
17332930
17363495
17640567
17671742
19235267
19294764
21594647
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in increased cleavage of and results in increased activity of CASP3 protein increases activity
/ increases cleavage
protein 16023083
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in increased cleavage of CASP3 protein increases cleavage
protein 19401701
20599780
21594647
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in increased expression of CASP3 mRNA increases expression
mRNA 16101141
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Curcumin results in increased expression of CASP3 protein increases expression
protein 18555241
D003474 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Glutathione inhibits the reaction [Curcumin results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 17640567
D003474 837 CASP4
ICE(rel)II
ICEREL-II
ICH-2
Mih1/TX
TX
caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57) Curcumin results in increased expression of CASP4 mRNA increases expression
mRNA 16101141
D003474 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) [Curcumin co-treated with Sirolimus] results in increased activity of CASP7 protein affects cotreatment
/ increases activity
protein 19373661
D003474 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) Curcumin results in decreased expression of CASP7 mRNA decreases expression
mRNA 16101141
D003474 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) Curcumin results in increased cleavage of and results in increased activity of CASP7 protein increases activity
/ increases cleavage
protein 16023083
D003474 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Curcumin results in decreased expression of CASP8 protein decreases expression
protein 17148446
D003474 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Curcumin results in increased activity of CASP8 protein increases activity
protein 17096185
D003474 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Curcumin results in increased cleavage of and results in increased activity of CASP8 protein increases activity
/ increases cleavage
protein 16173963
D003474 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Curcumin results in increased cleavage of CASP8 protein increases cleavage
protein 14555224
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) [Curcumin co-treated with arsenic trioxide] results in increased cleavage of CASP9 protein affects cotreatment
/ increases cleavage
protein 20605902
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) [Curcumin co-treated with lonidamine] results in increased cleavage of CASP9 protein affects cotreatment
/ increases cleavage
protein 20605902
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) [Curcumin co-treated with Sirolimus] results in increased activity of CASP9 protein affects cotreatment
/ increases activity
protein 19373661
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Curcumin results in decreased expression of CASP9 mRNA decreases expression
mRNA 16101141
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Curcumin results in decreased expression of CASP9 protein decreases expression
protein 17148446
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Curcumin results in increased activity of CASP9 protein increases activity
protein 17671742
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Curcumin results in increased cleavage of and results in increased activity of CASP9 protein increases activity
/ increases cleavage
protein 16023083
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Curcumin results in increased cleavage of CASP9 protein increases cleavage
protein 14555224
21594647
D003474 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Curcumin results in increased expression of CASP9 protein increases expression
protein 18555241
D003474 847 CAT
catalase (EC:1.11.1.6) [arsenite co-treated with Curcumin] results in increased expression of CAT protein affects cotreatment
/ increases expression
protein 18392098
D003474 847 CAT
catalase (EC:1.11.1.6) Curcumin inhibits the reaction [Cisplatin results in decreased activity of CAT protein] decreases activity
/ decreases reaction
protein 21574897
D003474 847 CAT
catalase (EC:1.11.1.6) Curcumin inhibits the reaction [oxaliplatin results in decreased activity of CAT protein] decreases activity
/ decreases reaction
protein 21574897
D003474 55749 CCAR1
RP11-437A18.1
cell division cycle and apoptosis regulator 1 Curcumin results in increased expression of CCAR1 protein increases expression
protein 21594647
D003474 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] decreases reaction
/ increases expression
mRNA 17666914
D003474 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 protein] decreases reaction
/ increases expression
protein 17666914
D003474 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Curcumin results in increased expression of CCL2 mRNA increases expression
mRNA 17198877
D003474 890 CCNA2
CCN1
CCNA
cyclin A2 Curcumin inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein] decreases reaction
/ increases expression
protein 23222814
D003474 890 CCNA2
CCN1
CCNA
cyclin A2 Curcumin results in decreased expression of CCNA2 protein decreases expression
protein 23222814
D003474 891 CCNB1
CCNB
cyclin B1 Curcumin results in decreased expression of CCNB1 mRNA decreases expression
mRNA 18719366
D003474 891 CCNB1
CCNB
cyclin B1 Curcumin results in decreased expression of CCNB1 protein decreases expression
protein 17148446
19401701
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 calyculin A inhibits the reaction [Curcumin results in decreased expression of CCND1 protein] decreases expression
/ decreases reaction
protein 18790744
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin analog inhibits the reaction [TNF protein results in increased expression of CCND1 protein] decreases reaction
/ increases expression
protein 20599780
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin analog results in decreased expression of CCND1 protein decreases expression
protein 17041101
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 [Curcumin co-treated with Isoflavones] results in decreased expression of CCND1 protein affects cotreatment
/ decreases expression
protein 18640131
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin inhibits the reaction [Nicotine results in increased expression of CCND1 protein] decreases reaction
/ increases expression
protein 20727180
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin inhibits the reaction [Paclitaxel results in increased expression of CCND1 protein] decreases reaction
/ increases expression
protein 16243823
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA] decreases reaction
/ increases expression
mRNA 16219905
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein] decreases reaction
/ increases expression
protein 15489888
17640567
20599780
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin inhibits the reaction [VIP protein results in increased expression of CCND1 protein] decreases reaction
/ increases expression
protein 19189304
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin results in decreased expression of CCND1 mRNA decreases expression
mRNA 15486348
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin results in decreased expression of CCND1 protein decreases expression
protein 16023083
16959222
17041101
17148446
18226269
18316600
18593936
18790744
19372569
19573523
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Curcumin results in increased degradation of CCND1 protein increases degradation
protein 18156803
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]] decreases reaction
/ increases expression
protein 17640567
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 lactacystin inhibits the reaction [Curcumin results in increased degradation of CCND1 protein] decreases reaction
/ increases degradation
protein 18156803
D003474 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of CCND1 protein] decreases expression
/ increases reaction
protein 18226269
D003474 896 CCND3
cyclin D3 Curcumin inhibits the reaction [bisphenol A results in increased expression of CCND3 protein] decreases reaction
/ increases expression
protein 23222814
D003474 896 CCND3
cyclin D3 Curcumin results in decreased expression of CCND3 protein decreases expression
protein 23222814
D003474 898 CCNE1
CCNE
cyclin E1 Curcumin results in decreased expression of CCNE1 protein decreases expression
protein 17148446
D003474 898 CCNE1
CCNE
cyclin E1 Curcumin results in increased degradation of CCNE1 protein increases degradation
protein 18156803
D003474 898 CCNE1
CCNE
cyclin E1 lactacystin inhibits the reaction [Curcumin results in increased degradation of CCNE1 protein] decreases reaction
/ increases degradation
protein 18156803
D003474 9236 CCPG1
CPR8
cell cycle progression 1 Curcumin results in increased expression of CCPG1 mRNA increases expression
mRNA 17198877
D003474 929 CD14
CD14 molecule Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]] decreases reaction
/ increases expression
/ increases reaction
protein 18180316
D003474 929 CD14
CD14 molecule Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein] decreases reaction
/ increases expression
protein 18180316
D003474 948 CD36
BDPLT10
CHDS7
FAT
GP3B
GP4
GPIV
PASIV
SCARB3
CD36 molecule (thrombospondin receptor) Curcumin results in decreased expression of CD36 mRNA decreases expression
mRNA 16713233
D003474 958 CD40
Bp50
CDW40
TNFRSF5
p50
CD40 molecule, TNF receptor superfamily member 5 Curcumin results in decreased expression of CD40 mRNA decreases expression
mRNA 16101141
D003474 960 CD44
CDW44
CSPG8
ECMR-III
HCELL
HUTCH-I
IN
LHR
MC56
MDU2
MDU3
MIC4
Pgp1
CD44 molecule (Indian blood group) Curcumin results in increased expression of CD44 mRNA increases expression
mRNA 15713895
D003474 1604 CD55
CR
CROM
DAF
TC
CD55 molecule, decay accelerating factor for complement (Cromer blood group) Curcumin results in decreased expression of CD55 mRNA decreases expression
mRNA 17999991
D003474 8555 CDC14B
CDC14B3
Cdc14B1
Cdc14B2
hCDC14B
cell division cycle 14B (EC:3.1.3.16 3.1.3.48) Curcumin results in increased expression of CDC14B mRNA increases expression
mRNA 17198877
D003474 991 CDC20
CDC20A
bA276H19.3
p55CDC
cell division cycle 20 Curcumin results in decreased expression of CDC20 mRNA decreases expression
mRNA 22258452
D003474 995 CDC25C
CDC25
PPP1R60
cell division cycle 25C (EC:3.1.3.48) Curcumin results in increased phosphorylation of CDC25C protein increases phosphorylation
protein 19401701
D003474 999 CDH1
Arc-1
CD324
CDHE
ECAD
LCAM
UVO
cadherin 1, type 1, E-cadherin (epithelial) Curcumin results in increased expression of CDH1 protein increases expression
protein 19573523
D003474 1009 CDH11
CAD11
CDHOB
OB
OSF-4
cadherin 11, type 2, OB-cadherin (osteoblast) Curcumin results in decreased expression of CDH11 protein decreases expression
protein 18025290
D003474 1015 CDH17
CDH16
HPT-1
HPT1
cadherin 17, LI cadherin (liver-intestine) Curcumin results in decreased expression of CDH17 mRNA decreases expression
mRNA 17198877
D003474 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Curcumin results in decreased expression of CDK1 mRNA decreases expression
mRNA 22258452
D003474 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Curcumin results in decreased expression of CDK1 protein decreases expression
protein 17148446
19401701
D003474 1017 CDK2
p33(CDK2)
cyclin-dependent kinase 2 (EC:2.7.11.22) Curcumin inhibits the reaction [bisphenol A results in increased expression of CDK2 protein] decreases reaction
/ increases expression
protein 23222814
D003474 1017 CDK2
p33(CDK2)
cyclin-dependent kinase 2 (EC:2.7.11.22) Curcumin results in decreased expression of CDK2 protein decreases expression
protein 23222814
D003474 1019 CDK4
CMM3
PSK-J3
cyclin-dependent kinase 4 (EC:2.7.11.22) Curcumin results in decreased expression of CDK4 protein decreases expression
protein 18156803
D003474 1021 CDK6
PLSTIRE
cyclin-dependent kinase 6 (EC:2.7.11.22) Curcumin results in decreased expression of CDK6 protein decreases expression
protein 18156803
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Curcumin inhibits the reaction [bisphenol A results in decreased expression of CDKN1A protein] decreases expression
/ decreases reaction
protein 23222814
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Curcumin results in decreased expression of CDKN1A protein decreases expression
protein 17148446
17332326
18593936
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNA decreases expression
mRNA 17332326
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Curcumin results in increased expression of CDKN1A mRNA increases expression
mRNA 15713895
18161303
18316600
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Curcumin results in increased expression of CDKN1A protein increases expression
protein 18156803
18161303
18226269
18316600
23222814
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) EGR1 protein affects the reaction [Curcumin results in increased expression of CDKN1A protein] affects reaction
/ increases expression
protein 18316600
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) EGR1 protein promotes the reaction [Curcumin results in increased expression of CDKN1A mRNA] increases expression
/ increases reaction
mRNA 18316600
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) MAPK1 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA] affects reaction
/ increases expression
mRNA 18316600
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) MAPK8 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA] affects reaction
/ increases expression
mRNA 18316600
D003474 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1A protein] increases expression
/ increases reaction
protein 18226269
D003474 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Curcumin results in decreased expression of CDKN1B protein decreases expression
protein 18593936
D003474 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Curcumin results in increased expression of CDKN1B mRNA increases expression
mRNA 15713895
D003474 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Curcumin results in increased expression of CDKN1B protein increases expression
protein 18156803
18226269
D003474 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1B protein] increases expression
/ increases reaction
protein 18226269
D003474 1029 CDKN2A
ARF
CDK4I
CDKN2
CMM2
INK4
INK4A
MLM
MTS-1
MTS1
P14
P14ARF
P16
P16-INK4A
P16INK4
P16INK4A
P19
P19ARF
TP16
cyclin-dependent kinase inhibitor 2A Curcumin results in decreased expression of CDKN2A protein decreases expression
protein 17148446
D003474 1029 CDKN2A
ARF
CDK4I
CDKN2
CMM2
INK4
INK4A
MLM
MTS-1
MTS1
P14
P14ARF
P16
P16-INK4A
P16INK4
P16INK4A
P19
P19ARF
TP16
cyclin-dependent kinase inhibitor 2A Curcumin results in increased expression of CDKN2A protein increases expression
protein 18156803
D003474 8837 CFLAR
CASH
CASP8AP1
CLARP
Casper
FLAME
FLAME-1
FLAME1
FLIP
I-FLICE
MRIT
c-FLIP
c-FLIPL
c-FLIPR
c-FLIPS
CASP8 and FADD-like apoptosis regulator Curcumin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA] decreases reaction
/ increases expression
mRNA 16219905
D003474 8837 CFLAR
CASH
CASP8AP1
CLARP
Casper
FLAME
FLAME-1
FLAME1
FLIP
I-FLICE
MRIT
c-FLIP
c-FLIPL
c-FLIPR
c-FLIPS
CASP8 and FADD-like apoptosis regulator Curcumin results in decreased expression of CFLAR protein decreases expression
protein 16173963
D003474 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Adenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form] affects reaction
/ increases activity
protein 17178710
D003474 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Curcumin results in increased activity of CFTR protein increases activity
protein 15582996
17178710
D003474 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Curcumin results in increased activity of CFTR protein mutant form increases activity
protein 15582996
D003474 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) [PRKCA protein results in increased phosphorylation of CFTR protein] promotes the reaction [Curcumin results in increased activity of CFTR protein] increases activity
/ increases phosphorylation
/ increases reaction
protein 17178710
D003474 1111 CHEK1
CHK1
checkpoint kinase 1 (EC:2.7.11.1) CHEK1 protein results in decreased susceptibility to Curcumin decreases response to substance
protein 18602917
D003474 1111 CHEK1
CHK1
checkpoint kinase 1 (EC:2.7.11.1) Curcumin results in increased activity of CHEK1 protein increases activity
protein 18602917
D003474 1111 CHEK1
CHK1
checkpoint kinase 1 (EC:2.7.11.1) Curcumin results in increased phosphorylation of CHEK1 protein increases phosphorylation
protein 19401701
D003474 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) [Curcumin co-treated with Dihydrotestosterone] results in increased phosphorylation of CHEK2 protein affects cotreatment
/ increases phosphorylation
protein 21134073
D003474 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) [Curcumin co-treated with Metribolone] results in increased phosphorylation of CHEK2 protein affects cotreatment
/ increases phosphorylation
protein 21134073
D003474 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) Curcumin results in increased phosphorylation of CHEK2 protein increases phosphorylation
protein 21134073
D003474 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) Flutamide inhibits the reaction [[Dihydrotestosterone co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein] affects cotreatment
/ decreases reaction
/ increases phosphorylation
protein 21134073
D003474 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) [Isoflavones co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein affects cotreatment
/ increases phosphorylation
protein 21134073
D003474 1147 CHUK
IKBKA
IKK-alpha
IKK1
IKKA
NFKBIKA
TCF16
conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) Curcumin inhibits the reaction [TNF protein results in increased activity of CHUK protein] decreases reaction
/ increases activity
protein 15489888
16219905
D003474 1147 CHUK
IKBKA
IKK-alpha
IKK1
IKKA
NFKBIKA
TCF16
conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) Curcumin inhibits the reaction [TNFSF11 protein results in increased activity of CHUK protein] decreases reaction
/ increases activity
protein 15129424
D003474 1147 CHUK
IKBKA
IKK-alpha
IKK1
IKKA
NFKBIKA
TCF16
conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) Curcumin results in decreased activity of CHUK protein decreases activity
protein 16023083
16219905
D003474 1185 CLCN6
CLC-6
chloride channel, voltage-sensitive 6 Curcumin results in decreased expression of CLCN6 mRNA decreases expression
mRNA 17198877
D003474 1280 COL2A1
ANFH
AOM
COL11A3
SEDC
STL1
collagen, type II, alpha 1 Curcumin results in increased expression of COL2A1 mRNA increases expression
mRNA 18321735
D003474 1280 COL2A1
ANFH
AOM
COL11A3
SEDC
STL1
collagen, type II, alpha 1 Curcumin results in increased expression of COL2A1 protein increases expression
protein 19889203
D003474 1280 COL2A1
ANFH
AOM
COL11A3
SEDC
STL1
collagen, type II, alpha 1 [resveratrol co-treated with Curcumin] results in increased expression of COL2A1 protein affects cotreatment
/ increases expression
protein 19889203
D003474 1282 COL4A1
HANAC
ICH
POREN1
arresten
collagen, type IV, alpha 1 Curcumin results in increased expression of COL4A1 mRNA increases expression
mRNA 21594647
D003474 1287 COL4A5
ASLN
ATS
CA54
collagen, type IV, alpha 5 Curcumin results in decreased expression of COL4A5 mRNA decreases expression
mRNA 15713895
D003474 1387 CREBBP
CBP
KAT3A
RSTS
CREB binding protein (EC:2.3.1.48) Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 1435 CSF1
CSF-1
MCSF
colony stimulating factor 1 (macrophage) (EC:2.7.10.1) Curcumin inhibits the reaction [CSF1 protein results in increased phosphorylation of CSF1R protein] decreases reaction
/ increases phosphorylation
protein 15129424
D003474 1436 CSF1R
C-FMS
CD115
CSF-1R
CSFR
FIM2
FMS
HDLS
M-CSF-R
colony stimulating factor 1 receptor (EC:2.7.10.1) Curcumin inhibits the reaction [CSF1 protein results in increased phosphorylation of CSF1R protein] decreases reaction
/ increases phosphorylation
protein 15129424
D003474 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor Curcumin results in decreased expression of CTGF mRNA decreases expression
mRNA 17965732
D003474 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor Curcumin results in decreased expression of CTGF protein decreases expression
protein 19764552
D003474 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA] decreases expression
/ decreases reaction
mRNA 17965732
D003474 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor Lipopolysaccharides inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA] decreases expression
/ decreases reaction
mRNA 17965732
D003474 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor NFKBIA protein inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA] decreases expression
/ decreases reaction
mRNA 17965732
D003474 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor PPARG protein promotes the reaction [Curcumin results in decreased expression of CTGF mRNA] decreases expression
/ increases reaction
mRNA 17965732
D003474 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa Curcumin analog results in decreased expression of CTNNB1 mRNA decreases expression
mRNA 17041101
D003474 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa Curcumin analog results in increased degradation of CTNNB1 protein increases degradation
protein 17041101
D003474 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa Curcumin inhibits the reaction [CTNNB1 protein binds to TCF7L2 protein] affects binding
/ decreases reaction
protein 19294764
D003474 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa Curcumin results in decreased activity of [CTNNB1 protein binds to TCF7L2 protein] affects binding
/ decreases activity
protein 19294764
D003474 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa Curcumin results in decreased expression of CTNNB1 mRNA decreases expression
mRNA 17041101
D003474 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa Curcumin results in decreased expression of CTNNB1 protein decreases expression
protein 19573523
D003474 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa Curcumin results in increased degradation of CTNNB1 protein increases degradation
protein 17041101
D003474 2919 CXCL1
FSP
GRO1
GROa
MGSA
MGSA-a
NAP-3
SCYB1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Curcumin results in decreased expression of CXCL1 mRNA decreases expression
mRNA 17999991
D003474 2919 CXCL1
FSP
GRO1
GROa
MGSA
MGSA-a
NAP-3
SCYB1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Curcumin results in decreased expression of CXCL1 protein decreases expression
protein 17999991
D003474 2919 CXCL1
FSP
GRO1
GROa
MGSA
MGSA-a
NAP-3
SCYB1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA] affects reaction
/ decreases expression
mRNA 17999991
D003474 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 Curcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA] decreases reaction
/ increases expression
protein 18660423
D003474 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein] decreases reaction
/ increases phosphorylation
protein 18660423
D003474 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein] decreases reaction
/ increases phosphorylation
protein 18660423
D003474 2920 CXCL2
CINC-2a
GRO2
GROb
MGSA-b
MIP-2a
MIP2
MIP2A
SCYB2
chemokine (C-X-C motif) ligand 2 Curcumin results in decreased expression of CXCL2 mRNA decreases expression
mRNA 17999991
D003474 2920 CXCL2
CINC-2a
GRO2
GROb
MGSA-b
MIP-2a
MIP2
MIP2A
SCYB2
chemokine (C-X-C motif) ligand 2 Curcumin results in decreased expression of CXCL2 protein decreases expression
protein 17999991
D003474 2920 CXCL2
CINC-2a
GRO2
GROb
MGSA-b
MIP-2a
MIP2
MIP2A
SCYB2
chemokine (C-X-C motif) ligand 2 NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL2 mRNA] affects reaction
/ decreases expression
mRNA 17999991
D003474 3577 CXCR1
C-C
C-C-CKR-1
CD128
CD181
CDw128a
CKR-1
CMKAR1
IL8R1
IL8RA
IL8RBA
chemokine (C-X-C motif) receptor 1 Curcumin results in increased expression of CXCR1 protein increases expression
protein 12216086
D003474 3579 CXCR2
CD182
CDw128b
CMKAR2
IL8R2
IL8RA
IL8RB
chemokine (C-X-C motif) receptor 2 Curcumin results in increased expression of CXCR2 protein increases expression
protein 12216086
D003474 7852 CXCR4
CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
chemokine (C-X-C motif) receptor 4 Curcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA] decreases reaction
/ increases expression
mRNA 18660423
D003474 7852 CXCR4
CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
chemokine (C-X-C motif) receptor 4 Curcumin results in decreased expression of CXCR4 mRNA decreases expression
mRNA 17198877
D003474 54205 CYCS
CYC
HCS
THC4
cytochrome c, somatic Curcumin affects the localization of CYCS protein affects localization
protein 19235267
D003474 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Curcumin inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein] decreases reaction
/ increases activity
protein 22867086
D003474 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 17012224
19018768
D003474 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] decreases reaction
/ increases expression
protein 19018768
D003474 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Curcumin promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA] increases expression
/ increases reaction
mRNA 22867086
D003474 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Curcumin results in decreased activity of CYP1A1 protein decreases activity
protein 15841493
22867086
D003474 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Curcumin results in decreased expression of CYP1A1 mRNA decreases expression
mRNA 20816778
D003474 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Curcumin results in increased expression of CYP1A1 mRNA increases expression
mRNA 11454723
22867086
D003474 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) Curcumin results in decreased activity of CYP1A2 protein decreases activity
protein 15841493
D003474 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] decreases reaction
/ increases expression
mRNA 19018768
D003474 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] decreases reaction
/ increases expression
protein 19018768
D003474 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Curcumin results in decreased expression of CYP1B1 mRNA decreases expression
mRNA 17637178
D003474 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Curcumin inhibits the reaction [Calcitriol results in increased expression of and results in increased activity of CYP3A4 protein] decreases reaction
/ increases activity
/ increases expression
protein 17270371
D003474 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Curcumin inhibits the reaction [Calcitriol results in increased expression of CYP3A4 mRNA] decreases reaction
/ increases expression
mRNA 17270371
17965521
D003474 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Curcumin results in decreased expression of CYP3A4 mRNA decreases expression
mRNA 20816778
D003474 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Curcumin results in increased expression of CYP3A4 mRNA increases expression
mRNA 17210444
D003474 27128 CYTH4
CYT4
DJ63G5.1
PSCD4
cytohesin 4 Curcumin results in increased expression of CYTH4 mRNA increases expression
mRNA 17198877
D003474 1616 DAXX
BING2
DAP6
EAP1
death-domain associated protein Curcumin results in increased expression of DAXX mRNA increases expression
mRNA 16101141
D003474 1634 DCN
CSCD
DSPG2
PG40
PGII
PGS2
SLRR1B
decorin Curcumin results in increased expression of DCN mRNA increases expression
mRNA 21594647
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA] decreases reaction
/ increases expression
mRNA 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of DDIT3 protein] decreases reaction
/ increases expression
protein 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Acetylcysteine inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA] decreases reaction
/ increases expression
mRNA 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Buthionine Sulfoximine promotes the reaction [Curcumin results in increased expression of DDIT3 mRNA] increases expression
/ increases reaction
mRNA 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Buthionine Sulfoximine promotes the reaction [Curcumin results in increased expression of DDIT3 protein] increases expression
/ increases reaction
protein 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Curcumin results in increased expression of DDIT3 mRNA increases expression
mRNA 16613838
17171638
18719366
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Curcumin results in increased expression of DDIT3 protein increases expression
protein 16613838
17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Glutathione inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA] decreases reaction
/ increases expression
mRNA 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Glutathione inhibits the reaction [Curcumin results in increased expression of DDIT3 protein] decreases reaction
/ increases expression
protein 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 PRKCD protein promotes the reaction [Curcumin results in increased expression of DDIT3 mRNA] increases expression
/ increases reaction
mRNA 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 rottlerin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA] decreases reaction
/ increases expression
mRNA 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA] decreases reaction
/ increases expression
mRNA 17171638
D003474 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 protein] decreases reaction
/ increases expression
protein 17171638
D003474 115265 DDIT4L
REDD2
Rtp801L
DNA-damage-inducible transcript 4-like Curcumin results in decreased expression of DDIT4L mRNA decreases expression
mRNA 17999991
D003474 115817 DHRS1
SDR19C1
dehydrogenase/reductase (SDR family) member 1 Curcumin results in decreased expression of DHRS1 mRNA decreases expression
mRNA 17198877
D003474 4189 DNAJB9
ERdj4
MDG-1
MDG1
MST049
MSTP049
DnaJ (Hsp40) homolog, subfamily B, member 9 Curcumin results in increased expression of DNAJB9 mRNA increases expression
mRNA 17999991
D003474 55332 DRAM1
DRAM
DNA-damage regulated autophagy modulator 1 Curcumin results in increased expression of DRAM1 mRNA increases expression
mRNA 21594647
D003474 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) Curcumin results in increased expression of DUSP1 mRNA increases expression
mRNA 15713895
D003474 11221 DUSP10
MKP-5
MKP5
dual specificity phosphatase 10 (EC:3.1.3.16 3.1.3.48) Curcumin results in increased expression of DUSP10 mRNA increases expression
mRNA 15713895
17151092
D003474 1847 DUSP5
DUSP
HVH3
dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48) Curcumin results in increased expression of DUSP5 mRNA increases expression
mRNA 17198877
D003474 1855 DVL1
DVL
DVL1L1
DVL1P1
dishevelled segment polarity protein 1 Curcumin results in decreased expression of DVL1 protein decreases expression
protein 19573523
D003474 8655 DYNLL1
DLC1
DLC8
DNCL1
DNCLC1
LC8
LC8a
PIN
hdlc1
dynein, light chain, LC8-type 1 Curcumin results in increased expression of DYNLL1 mRNA increases expression
mRNA 17198877
D003474 1875 E2F5
E2F-5
E2F transcription factor 5, p130-binding Curcumin results in decreased expression of E2F5 mRNA decreases expression
mRNA 15713895
D003474 10085 EDIL3
DEL1
EGF-like repeats and discoidin I-like domains 3 Curcumin results in decreased expression of EDIL3 mRNA decreases expression
mRNA 18421014
D003474 1950 EGF
HOMG4
URG
epidermal growth factor Curcumin inhibits the reaction [EGF protein results in increased expression of AQP3 protein] decreases reaction
/ increases expression
protein 18214481
D003474 1950 EGF
HOMG4
URG
epidermal growth factor Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein] decreases reaction
/ increases phosphorylation
protein 18214481
D003474 1950 EGF
HOMG4
URG
epidermal growth factor Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] decreases reaction
/ increases phosphorylation
protein 10851300
15129424
18214481
D003474 1950 EGF
HOMG4
URG
epidermal growth factor Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 18214481
D003474 1950 EGF
HOMG4
URG
epidermal growth factor Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 18214481
D003474 1950 EGF
HOMG4
URG
epidermal growth factor Curcumin inhibits the reaction [EGF protein results in increased secretion of PTHLH protein] decreases reaction
/ increases secretion
protein 15129424
D003474 1950 EGF
HOMG4
URG
epidermal growth factor Curcumin results in decreased activity of EGF protein decreases activity
protein 15486348
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] decreases reaction
/ increases phosphorylation
protein 10851300
15129424
18214481
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin promotes the reaction [Folfox protocol results in decreased expression of EGFR protein] decreases expression
/ increases reaction
protein 17918158
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin promotes the reaction [Folfox protocol results in decreased phosphorylation of and results in decreased activity of EGFR protein] decreases activity
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin results in decreased expression of and results in decreased activity of EGFR protein decreases activity
/ decreases expression
protein 10851300
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin results in decreased expression of EGFR mRNA decreases expression
mRNA 15486348
18719366
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin results in decreased expression of EGFR protein decreases expression
protein 17918158
18719366
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein decreases activity
/ decreases phosphorylation
protein 17918158
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Curcumin results in decreased phosphorylation of EGFR protein decreases phosphorylation
protein 15486348
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Fluorouracil promotes the reaction [Curcumin results in decreased expression of EGFR protein] decreases expression
/ increases reaction
protein 17918158
D003474 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein] decreases activity
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Curcumin results in increased expression of EGR1 protein] decreases reaction
/ increases expression
protein 18316600
D003474 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 Curcumin results in decreased expression of EGR1 mRNA decreases expression
mRNA 17999991
D003474 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 Curcumin results in increased expression of EGR1 mRNA increases expression
mRNA 17198877
18316600
D003474 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 Curcumin results in increased expression of EGR1 protein increases expression
protein 18316600
D003474 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 EGR1 protein affects the reaction [Curcumin results in increased expression of CDKN1A protein] affects reaction
/ increases expression
protein 18316600
D003474 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 EGR1 protein promotes the reaction [Curcumin results in increased expression of CDKN1A mRNA] increases expression
/ increases reaction
protein 18316600
D003474 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 U 0126 inhibits the reaction [Curcumin results in increased expression of EGR1 protein] decreases reaction
/ increases expression
protein 18316600
D003474 10209 EIF1
A121
EIF-1
EIF1A
ISO1
SUI1
eukaryotic translation initiation factor 1 Curcumin results in decreased expression of EIF1 mRNA decreases expression
mRNA 17999991
D003474 1978 EIF4EBP1
4E-BP1
4EBP1
BP-1
PHAS-I
eukaryotic translation initiation factor 4E binding protein 1 calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of EIF4EBP1 protein] decreases phosphorylation
/ decreases reaction
protein 18790744
D003474 1978 EIF4EBP1
4E-BP1
4EBP1
BP-1
PHAS-I
eukaryotic translation initiation factor 4E binding protein 1 Curcumin inhibits the reaction [bisphenol A results in increased expression of EIF4EBP1 protein] decreases reaction
/ increases expression
protein 23222814
D003474 1978 EIF4EBP1
4E-BP1
4EBP1
BP-1
PHAS-I
eukaryotic translation initiation factor 4E binding protein 1 Curcumin results in decreased expression of EIF4EBP1 protein decreases expression
protein 23222814
D003474 1978 EIF4EBP1
4E-BP1
4EBP1
BP-1
PHAS-I
eukaryotic translation initiation factor 4E binding protein 1 Curcumin results in decreased phosphorylation of EIF4EBP1 protein decreases phosphorylation
protein 18790744
D003474 1981 EIF4G1
EIF-4G1
EIF4F
EIF4G
EIF4GI
P220
PARK18
eukaryotic translation initiation factor 4 gamma, 1 Curcumin results in decreased phosphorylation of EIF4G1 protein decreases phosphorylation
protein 18790744
D003474 1998 ELF2
EU32
NERF
NERF-1A
NERF-1B
NERF-1a,b
NERF-2
E74-like factor 2 (ets domain transcription factor) Curcumin results in decreased expression of ELF2 mRNA decreases expression
mRNA 15713895
D003474 2002 ELK1
ELK1, member of ETS oncogene family anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Curcumin results in increased phosphorylation of ELK1 protein] decreases reaction
/ increases phosphorylation
protein 18316600
D003474 2002 ELK1
ELK1, member of ETS oncogene family Curcumin results in increased phosphorylation of ELK1 protein increases phosphorylation
protein 18316600
D003474 2002 ELK1
ELK1, member of ETS oncogene family U 0126 inhibits the reaction [Curcumin results in increased phosphorylation of ELK1 protein] decreases reaction
/ increases phosphorylation
protein 18316600
D003474 2023 ENO1
ENO1L1
MPB1
NNE
PPH
enolase 1, (alpha) (EC:4.2.1.11) Curcumin results in decreased expression of ENO1 mRNA decreases expression
mRNA 16880289
D003474 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of EP300 protein] affects localization
/ decreases reaction
protein 17927689
D003474 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 mRNA] decreases expression
/ decreases reaction
mRNA 17927689
D003474 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 protein] decreases expression
/ decreases reaction
protein 17927689
D003474 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) Curcumin affects the localization of EP300 protein affects localization
protein 17927689
D003474 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [EP300 protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) Curcumin results in decreased expression of EP300 mRNA decreases expression
mRNA 17927689
D003474 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) Curcumin results in decreased expression of EP300 protein decreases expression
protein 17927689
D003474 2056 EPO
EP
MVCD2
erythropoietin Curcumin results in decreased expression of EPO mRNA decreases expression
mRNA 16880289
D003474 2064 ERBB2
CD340
HER-2
HER-2/neu
HER2
MLN_19
NEU
NGL
TKR1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) Curcumin analog results in decreased expression of ERBB2 mRNA decreases expression
mRNA 17041101
D003474 2064 ERBB2
CD340
HER-2
HER-2/neu
HER2
MLN_19
NEU
NGL
TKR1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) Curcumin analog results in decreased expression of ERBB2 protein decreases expression
protein 17041101
D003474 2064 ERBB2
CD340
HER-2
HER-2/neu
HER2
MLN_19
NEU
NGL
TKR1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased expression of and results in decreased activity of ERBB2 protein] decreases activity
/ decreases expression
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 2064 ERBB2
CD340
HER-2
HER-2/neu
HER2
MLN_19
NEU
NGL
TKR1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein] decreases activity
/ decreases expression
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 2064 ERBB2
CD340
HER-2
HER-2/neu
HER2
MLN_19
NEU
NGL
TKR1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein decreases activity
/ decreases expression
/ decreases phosphorylation
protein 17918158
D003474 2064 ERBB2
CD340
HER-2
HER-2/neu
HER2
MLN_19
NEU
NGL
TKR1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) Curcumin results in decreased expression of ERBB2 mRNA decreases expression
mRNA 17041101
18719366
D003474 2064 ERBB2
CD340
HER-2
HER-2/neu
HER2
MLN_19
NEU
NGL
TKR1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) Curcumin results in decreased expression of ERBB2 protein decreases expression
protein 17041101
18719366
D003474 2065 ERBB3
ErbB-3
HER3
LCCS2
MDA-BF-1
c-erbB-3
c-erbB3
erbB3-S
p180-ErbB3
p45-sErbB3
p85-sErbB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1) Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein] decreases activity
/ decreases expression
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 2065 ERBB3
ErbB-3
HER3
LCCS2
MDA-BF-1
c-erbB-3
c-erbB3
erbB3-S
p180-ErbB3
p45-sErbB3
p85-sErbB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1) Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein decreases activity
/ decreases expression
/ decreases phosphorylation
protein 17918158
D003474 2065 ERBB3
ErbB-3
HER3
LCCS2
MDA-BF-1
c-erbB-3
c-erbB3
erbB3-S
p180-ErbB3
p45-sErbB3
p85-sErbB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1) Curcumin results in decreased expression of ERBB3 mRNA decreases expression
mRNA 15713895
D003474 2065 ERBB3
ErbB-3
HER3
LCCS2
MDA-BF-1
c-erbB-3
c-erbB3
erbB3-S
p180-ErbB3
p45-sErbB3
p85-sErbB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1) Fluorouracil promotes the reaction [Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein] decreases activity
/ decreases expression
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 2067 ERCC1
COFS4
RAD10
UV20
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) Curcumin results in decreased expression of ERCC1 mRNA decreases expression
mRNA 17596214
21493726
D003474 2067 ERCC1
COFS4
RAD10
UV20
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) Curcumin results in decreased expression of ERCC1 protein decreases expression
protein 21493726
D003474 2067 ERCC1
COFS4
RAD10
UV20
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) [Curcumin results in decreased expression of ERCC1 protein] which results in increased susceptibility to Cisplatin decreases expression
/ increases response to substance
protein 21493726
D003474 2081 ERN1
IRE1
IRE1P
IRE1a
hIRE1p
endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1) Curcumin results in decreased expression of ERN1 mRNA decreases expression
mRNA 17999991
D003474 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Curcumin inhibits the reaction [bisphenol A results in increased expression of ESR1 protein] decreases reaction
/ increases expression
protein 23222814
D003474 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Curcumin inhibits the reaction [Estradiol results in increased degradation of ESR1 protein] decreases reaction
/ increases degradation
protein 15899841
D003474 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Curcumin inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein] decreases reaction
/ increases phosphorylation
protein 15899841
D003474 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Curcumin inhibits the reaction [fulvestrant results in increased degradation of ESR1 protein] decreases reaction
/ increases degradation
protein 15899841
D003474 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Curcumin results in decreased expression of ESR1 protein decreases expression
protein 18347134
D003474 2114 ETS2
ETS2IT1
v-ets avian erythroblastosis virus E26 oncogene homolog 2 Curcumin results in decreased expression of ETS2 protein decreases expression
protein 17332326
D003474 2152 F3
CD142
TF
TFA
coagulation factor III (thromboplastin, tissue factor) Curcumin inhibits the reaction [Heme results in increased expression of F3 mRNA] decreases reaction
/ increases expression
mRNA 18983524
D003474 84498 FAM120B
CCPG
KIAA1838
PGCC1
dJ894D12.1
family with sequence similarity 120B Curcumin results in decreased expression of FAM120B mRNA decreases expression
mRNA 17999991
D003474 356 FASLG
ALPS1B
APT1LG1
APTL
CD178
CD95-L
CD95L
FASL
TNFSF6
Fas ligand (TNF superfamily, member 6) Curcumin inhibits the reaction [[vorinostat co-treated with bortezomib] results in increased expression of FASLG protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 17351739
D003474 356 FASLG
ALPS1B
APT1LG1
APTL
CD178
CD95-L
CD95L
FASL
TNFSF6
Fas ligand (TNF superfamily, member 6) Curcumin results in decreased expression of FASLG mRNA decreases expression
mRNA 16101141
D003474 2224 FDPS
FPPS
FPS
farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10) Curcumin results in increased expression of FDPS mRNA increases expression
mRNA 16713233
D003474 2263 FGFR2
BBDS
BEK
BFR-1
CD332
CEK3
CFD1
ECT1
JWS
K-SAM
KGFR
TK14
TK25
fibroblast growth factor receptor 2 (EC:2.7.10.1) Curcumin results in decreased expression of FGFR2 mRNA decreases expression
mRNA 15713895
D003474 11259 FILIP1L
DOC-1
DOC1
GIP130
GIP90
filamin A interacting protein 1-like Curcumin results in increased expression of FILIP1L mRNA increases expression
mRNA 21594647
D003474 2321 FLT1
FLT
FLT-1
VEGFR-1
VEGFR1
fms-related tyrosine kinase 1 (EC:2.7.10.1) Curcumin results in decreased expression of FLT1 protein decreases expression
protein 18593936
D003474 2335 FN1
CIG
ED-B
FINC
FN
FNZ
GFND
GFND2
LETS
MSF
fibronectin 1 Curcumin inhibits the reaction [Glucose results in increased expression of FN1 mRNA] decreases reaction
/ increases expression
mRNA 12388107
D003474 2335 FN1
CIG
ED-B
FINC
FN
FNZ
GFND
GFND2
LETS
MSF
fibronectin 1 Curcumin inhibits the reaction [Glucose results in increased expression of FN1 protein] decreases reaction
/ increases expression
protein 12388107
D003474 2335 FN1
CIG
ED-B
FINC
FN
FNZ
GFND
GFND2
LETS
MSF
fibronectin 1 Curcumin results in decreased expression of FN1 mRNA decreases expression
mRNA 18555241
D003474 2342 FNTB
FPTB
farnesyltransferase, CAAX box, beta (EC:2.5.1.58) Curcumin results in increased expression of FNTB mRNA increases expression
mRNA 17999991
D003474 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog Curcumin results in decreased expression of FOS mRNA decreases expression
mRNA 17999991
D003474 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog Curcumin results in increased expression of FOS mRNA increases expression
mRNA 15713895
D003474 8061 FOSL1
FRA
FRA1
fra-1
FOS-like antigen 1 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]] decreases reaction
/ increases expression
protein 17148446
D003474 8061 FOSL1
FRA
FRA1
fra-1
FOS-like antigen 1 Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]] affects binding
/ decreases reaction
/ increases reaction
protein 17148446
D003474 8061 FOSL1
FRA
FRA1
fra-1
FOS-like antigen 1 Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein] decreases reaction
/ increases expression
protein 17148446
D003474 8061 FOSL1
FRA
FRA1
fra-1
FOS-like antigen 1 Curcumin results in increased ubiquitination of FOSL1 protein increases ubiquitination
protein 17148446
D003474 2355 FOSL2
FRA2
FOS-like antigen 2 Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein] decreases reaction
/ increases expression
protein 17148446
D003474 2355 FOSL2
FRA2
FOS-like antigen 2 Curcumin results in decreased expression of FOSL2 mRNA decreases expression
mRNA 17999991
D003474 3169 FOXA1
HNF3A
TCF3A
forkhead box A1 Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 3169 FOXA1
HNF3A
TCF3A
forkhead box A1 Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to TMPRSS2 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 2295 FOXF2
FKHL6
FREAC-2
FREAC2
forkhead box F2 Curcumin results in decreased expression of FOXF2 mRNA decreases expression
mRNA 15713895
D003474 2308 FOXO1
FKH1
FKHR
FOXO1A
forkhead box O1 Curcumin results in decreased phosphorylation of FOXO1 protein decreases phosphorylation
protein 18790744
D003474 2521 FUS
ALS6
ETM4
FUS1
HNRNPP2
POMP75
TLS
fused in sarcoma Curcumin results in decreased expression of FUS mRNA decreases expression
mRNA 17999991
D003474 2521 FUS
ALS6
ETM4
FUS1
HNRNPP2
POMP75
TLS
fused in sarcoma Curcumin results in increased expression of FUS mRNA increases expression
mRNA 17198877
D003474 8321 FZD1
frizzled family receptor 1 Curcumin results in decreased expression of FZD1 mRNA decreases expression
mRNA 15713895
D003474 1647 GADD45A
DDIT1
GADD45
growth arrest and DNA-damage-inducible, alpha Curcumin results in increased expression of GADD45A mRNA increases expression
mRNA 16101141
18719366
D003474 2621 GAS6
AXLLG
AXSF
growth arrest-specific 6 Curcumin results in increased expression of GAS6 mRNA increases expression
mRNA 21594647
D003474 2624 GATA2
DCML
MONOMAC
NFE1B
GATA binding protein 2 Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 2624 GATA2
DCML
MONOMAC
NFE1B
GATA binding protein 2 Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to TMPRSS2 enhancer]] affects binding
/ decreases reaction
/ increases reaction
protein 22258452
D003474 2624 GATA2
DCML
MONOMAC
NFE1B
GATA binding protein 2 Curcumin inhibits the reaction [GATA2 protein results in increased expression of KLK3 mRNA] decreases reaction
/ increases expression
protein 22258452
D003474 2729 GCLC
GCL
GCS
GLCL
GLCLC
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) Curcumin results in increased activity of GCLC protein increases activity
protein 10514034
D003474 2730 GCLM
GLCLR
glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) Curcumin results in increased expression of GCLM mRNA increases expression
mRNA 17198877
17999991
19188863
D003474 2730 GCLM
GLCLR
glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) Curcumin results in increased expression of GCLM protein increases expression
protein 19188863
D003474 2852 GPER1
CEPR
CMKRL2
DRY12
FEG-1
GPCR-Br
GPER
GPR30
LERGU
LERGU2
LyGPR
G protein-coupled estrogen receptor 1 Curcumin results in decreased expression of GPER1 mRNA decreases expression
mRNA 17198877
D003474 2932 GSK3B
glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) Curcumin results in decreased phosphorylation of GSK3B protein decreases phosphorylation
protein 18790744
D003474 2932 GSK3B
glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) Curcumin results in increased expression of GSK3B protein increases expression
protein 19573523
D003474 2941 GSTA4
GSTA4-4
GTA4
glutathione S-transferase alpha 4 (EC:2.5.1.18) Curcumin results in increased activity of GSTA4 protein increases activity
protein 10514034
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin binds to and results in decreased activity of GSTP1 protein affects binding
/ decreases activity
protein 9463521
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide] decreases reaction
/ decreases response to substance
protein 15999103
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA] decreases reaction
/ increases expression
mRNA 14555224
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin promotes the reaction [NFE2L2 protein binds to GSTP1 promoter] affects binding
/ increases reaction
promoter 17449203
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin promotes the reaction [NFE2L2 protein results in increased expression of GSTP1 mRNA] increases expression
/ increases reaction
mRNA 17449203
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin results in decreased expression of GSTP1 mRNA decreases expression
mRNA 14555224
18414057
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin results in decreased expression of GSTP1 protein decreases expression
protein 14555224
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin results in increased expression of GSTP1 mRNA increases expression
mRNA 16101141
17449203
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Curcumin results in increased expression of GSTP1 protein increases expression
protein 14742295
D003474 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) [sulfinosine co-treated with Curcumin] results in decreased expression of GSTP1 mRNA affects cotreatment
/ decreases expression
mRNA 18414057
D003474 283120 H19
ASM
ASM1
BWS
D11S813E
LINC00008
NCRNA00008
PRO2605
WT2
H19, imprinted maternally expressed transcript (non-protein coding) Curcumin results in decreased expression of H19 mRNA decreases expression
mRNA 18348204
D003474 8971 H1FX
H1X
H1 histone family, member X Curcumin results in decreased expression of H1FX mRNA decreases expression
mRNA 17198877
D003474 3014 H2AFX
H2A.X
H2A/X
H2AX
H2A histone family, member X [Curcumin co-treated with Metribolone] results in increased phosphorylation of H2AFX protein affects cotreatment
/ increases phosphorylation
protein 21134073
D003474 3014 H2AFX
H2A.X
H2A/X
H2AX
H2A histone family, member X Curcumin results in increased phosphorylation of H2AFX protein increases phosphorylation
protein 19401701
21134073
D003474 3014 H2AFX
H2A.X
H2A/X
H2AX
H2A histone family, member X [Isoflavones co-treated with Curcumin] results in increased phosphorylation of H2AFX protein affects cotreatment
/ increases phosphorylation
protein 21134073
D003474 10767 HBS1L
EF-1a
ERFS
HBS1
HSPC276
HBS1-like (S. cerevisiae) Curcumin results in decreased expression of HBS1L mRNA decreases expression
mRNA 18421014
D003474 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of HDAC1 protein] affects localization
/ decreases reaction
protein 17927689
D003474 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 mRNA] decreases expression
/ decreases reaction
mRNA 17927689
D003474 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 protein] decreases expression
/ decreases reaction
protein 17927689
D003474 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) Curcumin affects the localization of HDAC1 protein affects localization
protein 17927689
D003474 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) Curcumin results in decreased expression of HDAC1 mRNA decreases expression
mRNA 17927689
D003474 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) Curcumin results in decreased expression of HDAC1 protein decreases expression
protein 17927689
18161303
D003474 3066 HDAC2
HD2
RPD3
YAF1
histone deacetylase 2 (EC:3.5.1.98) Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased activity of HDAC2 protein] decreases activity
/ decreases reaction
protein 18421014
D003474 3066 HDAC2
HD2
RPD3
YAF1
histone deacetylase 2 (EC:3.5.1.98) Curcumin inhibits the reaction [Smoke results in decreased activity of HDAC2 protein] decreases activity
/ decreases reaction
protein 18421014
D003474 3066 HDAC2
HD2
RPD3
YAF1
histone deacetylase 2 (EC:3.5.1.98) Curcumin inhibits the reaction [Smoke results in increased degradation of and results in decreased expression of HDAC2 protein] decreases expression
/ decreases reaction
/ increases degradation
protein 18421014
D003474 8841 HDAC3
HD3
RPD3
RPD3-2
histone deacetylase 3 (EC:3.5.1.98) Curcumin results in decreased expression of HDAC3 protein decreases expression
protein 17927689
D003474 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Curcumin results in decreased activity of HIF1A protein decreases activity
protein 16880289
D003474 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Curcumin results in decreased expression of and results in decreased activity of HIF1A protein decreases activity
/ decreases expression
protein 18682687
D003474 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Curcumin results in decreased expression of HIF1A mRNA decreases expression
mRNA 18682687
D003474 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) VHL protein promotes the reaction [Curcumin results in decreased expression of HIF1A protein] decreases expression
/ increases reaction
protein 18682687
D003474 3017 HIST1H2BD
H2B.1B
H2B/b
H2BFB
HIRIP2
dJ221C16.6
histone cluster 1, H2bd Curcumin results in increased expression of HIST1H2BD mRNA increases expression
mRNA 17999991
D003474 8363 HIST1H4J
H4/e
H4F2iv
H4FE
dJ160A22.2
histone cluster 1, H4j Curcumin results in increased expression of HIST1H4J mRNA increases expression
mRNA 15713895
D003474 554313 HIST2H4B
H4/o
histone cluster 2, H4b Curcumin results in increased expression of HIST2H4B mRNA increases expression
mRNA 17198877
D003474 128312 HIST3H2BB
H2Bb
histone cluster 3, H2bb Curcumin results in increased expression of HIST3H2BB mRNA increases expression
mRNA 15713895
D003474 3116 HLA-DPB2
DP2B
DPB2
DPbeta2
HLA-DP2B
major histocompatibility complex, class II, DP beta 2 (pseudogene) Curcumin results in decreased expression of HLA-DPB2 mRNA decreases expression
mRNA 18421014
D003474 3156 HMGCR
LDLCQ3
3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) Curcumin results in increased expression of HMGCR mRNA increases expression
mRNA 16713233
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
20938987
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Acetylcysteine inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
20938987
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein decreases reaction
/ increases expression
protein 17973899
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Curcumin results in increased activity of HMOX1 protein increases activity
protein 17464175
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Curcumin results in increased expression of and results in increased activity of HMOX1 protein increases activity
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Curcumin results in increased expression of HMOX1 mRNA increases expression
mRNA 17464175
17999991
18357586
18719366
19188863
22771723
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Curcumin results in increased expression of HMOX1 protein increases expression
protein 14742295
17464175
19188863
20938987
22771723
23266269
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Cycloheximide inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Dactinomycin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Egtazic Acid inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Go 6976 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Hemin promotes the reaction [Curcumin results in increased expression of HMOX1 mRNA] increases expression
/ increases reaction
mRNA 17464175
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) HMOX1 protein results in decreased susceptibility to Curcumin decreases response to substance
protein 22771723
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) MAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein] affects reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Ro 31-8220 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) rottlerin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) SB 203580 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 18357586
D003474 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) tin protoporphyrin IX inhibits the reaction [Curcumin results in increased activity of HMOX1 protein] decreases reaction
/ increases activity
protein 18357586
D003474 693712 Curcumin results in decreased expression of HNRPA1 mRNA decreases expression
mRNA 17999991
D003474 79256 Curcumin results in decreased expression of HNRPD mRNA decreases expression
mRNA 17999991
D003474 3215 HOXB5
HHO.C10
HOX2
HOX2A
HU-1
Hox2.1
homeobox B5 Curcumin results in increased expression of HOXB5 mRNA increases expression
mRNA 18421014
D003474 3251 HPRT1
HGPRT
HPRT
hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8) Curcumin results in increased expression of HPRT1 mRNA increases expression
mRNA 16101141
D003474 3297 HSF1
HSTF1
heat shock transcription factor 1 Curcumin promotes the reaction [HSF1 protein binds to HSF1 protein] affects binding
/ increases reaction
protein 11322385
D003474 3308 HSPA4
APG-2
HS24/P52
HSPH2
RY
hsp70
hsp70RY
heat shock 70kDa protein 4 Curcumin results in increased expression of HSPA4 mRNA increases expression
mRNA 11322385
D003474 3308 HSPA4
APG-2
HS24/P52
HSPH2
RY
hsp70
hsp70RY
heat shock 70kDa protein 4 Curcumin results in increased expression of HSPA4 protein increases expression
protein 11322385
D003474 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] decreases reaction
/ increases expression
protein 17973899
D003474 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 Curcumin inhibits the reaction [Paclitaxel results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 16243823
D003474 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] decreases reaction
/ increases expression
mRNA 16219905
17666914
D003474 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 17666914
17973899
D003474 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein decreases reaction
/ increases expression
protein 17973899
D003474 3397 ID1
ID
bHLHb24
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Curcumin results in decreased expression of ID1 mRNA decreases expression
mRNA 21594647
D003474 3398 ID2
GIG8
ID2A
ID2H
bHLHb26
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein Curcumin results in decreased expression of ID2 mRNA decreases expression
mRNA 21594647
D003474 3399 ID3
HEIR-1
bHLHb25
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein Curcumin results in decreased expression of ID3 mRNA decreases expression
mRNA 21594647
D003474 3620 IDO1
IDO
IDO-1
INDO
indoleamine 2,3-dioxygenase 1 (EC:1.13.11.52) Curcumin results in decreased expression of IDO1 mRNA decreases expression
mRNA 18348204
D003474 3439 IFNA1
IFL
IFN
IFN-ALPHA
IFN-alphaD
IFNA13
IFNA@
interferon, alpha 1 Curcumin inhibits the reaction [IFNA1 protein results in increased expression of IFNAR2 protein] decreases reaction
/ increases expression
protein 17979888
D003474 3439 IFNA1
IFL
IFN
IFN-ALPHA
IFN-alphaD
IFNA13
IFNA@
interferon, alpha 1 Curcumin promotes the reaction [IFNA1 protein results in increased expression of IFNAR1 protein] increases expression
/ increases reaction
protein 17979888
D003474 3439 IFNA1
IFL
IFN
IFN-ALPHA
IFN-alphaD
IFNA13
IFNA@
interferon, alpha 1 Curcumin promotes the reaction [IFNA1 protein results in increased expression of IL10 protein] increases expression
/ increases reaction
protein 17979888
D003474 3454 IFNAR1
AVP
IFN-alpha-REC
IFNAR
IFNBR
IFRC
interferon (alpha, beta and omega) receptor 1 Curcumin promotes the reaction [IFNA1 protein results in increased expression of IFNAR1 protein] increases expression
/ increases reaction
protein 17979888
D003474 3454 IFNAR1
AVP
IFN-alpha-REC
IFNAR
IFNBR
IFRC
interferon (alpha, beta and omega) receptor 1 Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR1 protein] increases expression
/ increases reaction
protein 17979888
D003474 3455 IFNAR2
IFN-R
IFN-alpha-REC
IFNABR
IFNARB
interferon (alpha, beta and omega) receptor 2 Curcumin inhibits the reaction [IFNA1 protein results in increased expression of IFNAR2 protein] decreases reaction
/ increases expression
protein 17979888
D003474 3455 IFNAR2
IFN-R
IFN-alpha-REC
IFNABR
IFNARB
interferon (alpha, beta and omega) receptor 2 Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR2 protein] increases expression
/ increases reaction
protein 17979888
D003474 3456 IFNB1
IFB
IFF
IFNB
interferon, beta 1, fibroblast Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR1 protein] increases expression
/ increases reaction
protein 17979888
D003474 3456 IFNB1
IFB
IFF
IFNB
interferon, beta 1, fibroblast Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR2 protein] increases expression
/ increases reaction
protein 17979888
D003474 3456 IFNB1
IFB
IFF
IFNB
interferon, beta 1, fibroblast Curcumin promotes the reaction [IFNB1 protein results in increased expression of IL10 protein] increases expression
/ increases reaction
protein 17979888
D003474 3456 IFNB1
IFB
IFF
IFNB
interferon, beta 1, fibroblast Curcumin promotes the reaction [IFNB1 protein results in increased phosphorylation of STAT4 protein] increases phosphorylation
/ increases reaction
protein 17979888
D003474 3458 IFNG
IFG
IFI
interferon, gamma Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT1 protein] decreases reaction
/ increases expression
/ increases phosphorylation
protein 16959222
D003474 3458 IFNG
IFG
IFI
interferon, gamma Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT3 protein] decreases reaction
/ increases expression
/ increases phosphorylation
protein 16959222
D003474 56832 IFNK
IFNT1
INFE1
RP11-27J8.1
interferon, kappa Curcumin results in decreased expression of IFNK mRNA decreases expression
mRNA 18421014
D003474 3479 IGF1
IGF-I
IGF1A
IGFI
insulin-like growth factor 1 (somatomedin C) Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein] decreases reaction
/ increases activity
protein 17499312
D003474 3479 IGF1
IGF-I
IGF1A
IGFI
insulin-like growth factor 1 (somatomedin C) Curcumin results in decreased activity of IGF1 protein decreases activity
protein 17499312
D003474 3479 IGF1
IGF-I
IGF1A
IGFI
insulin-like growth factor 1 (somatomedin C) Curcumin results in decreased secretion of IGF1 protein decreases secretion
protein 17499312
D003474 3480 IGF1R
CD221
IGFIR
IGFR
JTK13
insulin-like growth factor 1 receptor (EC:2.7.10.1) Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein] decreases reaction
/ increases activity
protein 17499312
D003474 3480 IGF1R
CD221
IGFIR
IGFR
JTK13
insulin-like growth factor 1 receptor (EC:2.7.10.1) Curcumin promotes the reaction [Folfox protocol results in decreased phosphorylation of and results in decreased activity of IGF1R protein] decreases activity
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 3480 IGF1R
CD221
IGFIR
IGFR
JTK13
insulin-like growth factor 1 receptor (EC:2.7.10.1) Curcumin results in decreased expression of IGF1R mRNA decreases expression
mRNA 17499312
D003474 3480 IGF1R
CD221
IGFIR
IGFR
JTK13
insulin-like growth factor 1 receptor (EC:2.7.10.1) Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein decreases activity
/ decreases phosphorylation
protein 17918158
D003474 3480 IGF1R
CD221
IGFIR
IGFR
JTK13
insulin-like growth factor 1 receptor (EC:2.7.10.1) Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein] decreases activity
/ decreases phosphorylation
/ increases reaction
protein 17918158
D003474 3486 IGFBP3
BP-53
IBP3
insulin-like growth factor binding protein 3 Curcumin results in decreased expression of IGFBP3 mRNA decreases expression
mRNA 16101141
D003474 3486 IGFBP3
BP-53
IBP3
insulin-like growth factor binding protein 3 Curcumin results in increased expression of IGFBP3 mRNA increases expression
mRNA 21594647
D003474 3486 IGFBP3
BP-53
IBP3
insulin-like growth factor binding protein 3 Curcumin results in increased secretion of IGFBP3 protein increases secretion
protein 17499312
D003474 3490 IGFBP7
AGM
FSTL2
IBP-7
IGFBP-7
IGFBP-7v
IGFBPRP1
MAC25
PSF
RAMSVPS
TAF
insulin-like growth factor binding protein 7 Curcumin results in increased expression of IGFBP7 mRNA increases expression
mRNA 21594647
D003474 3543 IGLL1
14.1
AGM2
CD179b
IGL1
IGL5
IGLJ14.1
IGLL
IGO
IGVPB
VPREB2
immunoglobulin lambda-like polypeptide 1 Curcumin results in decreased expression of IGLL1 mRNA decreases expression
mRNA 17198877
D003474 3551 IKBKB
IKK-beta
IKK2
IKKB
NFKBIKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) Curcumin inhibits the reaction [TNF protein results in increased activity of IKBKB protein] decreases reaction
/ increases activity
protein 16219905
D003474 3551 IKBKB
IKK-beta
IKK2
IKKB
NFKBIKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) Curcumin results in decreased activity of IKBKB protein decreases activity
protein 16023083
16219905
D003474 3551 IKBKB
IKK-beta
IKK2
IKKB
NFKBIKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA] decreases expression
/ decreases reaction
protein 17965732
D003474 3586 IL10
CSIF
GVHDS
IL-10
IL10A
TGIF
interleukin 10 Curcumin promotes the reaction [IFNA1 protein results in increased expression of IL10 protein] increases expression
/ increases reaction
protein 17979888
D003474 3586 IL10
CSIF
GVHDS
IL-10
IL10A
TGIF
interleukin 10 Curcumin promotes the reaction [IFNB1 protein results in increased expression of IL10 protein] increases expression
/ increases reaction
protein 17979888
D003474 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA mRNA] decreases reaction
/ increases expression
protein 16368150
D003474 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA protein] decreases reaction
/ increases expression
protein 16368150
D003474 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to IL18 promoter]] affects binding
/ decreases reaction
/ increases reaction
promoter 17399992
D003474 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to IL18 promoter]] affects binding
/ decreases reaction
/ increases reaction
promoter 17399992
D003474 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Curcumin results in decreased expression of IL18 mRNA decreases expression
mRNA 17399992
D003474 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Curcumin results in decreased expression of IL18 protein decreases expression
protein 17399992
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]] affects binding
/ decreases reaction
/ increases reaction
protein 16819191
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in decreased expression of ITGB1 protein] decreases expression
/ decreases reaction
protein 17291458
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] decreases reaction
/ increases degradation
protein 16819191
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased expression of A4GALT mRNA] decreases reaction
/ increases expression
protein 16819191
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP9 protein] decreases reaction
/ increases expression
protein 17291458
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] decreases reaction
/ increases expression
protein 17291458
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased localization of RELA protein] decreases reaction
/ increases localization
protein 16819191
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of AKT1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 17291458
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of and results in increased localization of RELA protein] decreases reaction
/ increases activity
/ increases localization
/ increases phosphorylation
protein 17291458
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein] decreases reaction
/ increases phosphorylation
protein 17291458
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL6 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
protein 17151092
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL8 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
protein 17151092
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 17151092
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein] affects cotreatment
/ decreases reaction
/ increases phosphorylation
protein 17151092
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin inhibits the reaction [TNF protein results in decreased expression of IL1B mRNA] decreases expression
/ decreases reaction
mRNA 17273796
D003474 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Curcumin results in decreased expression of IL1B mRNA decreases expression
mRNA 20816778
D003474 3558 IL2
IL-2
TCGF
lymphokine
interleukin 2 Curcumin results in decreased expression of and results in decreased secretion of IL2 protein decreases expression
/ decreases secretion
protein 19761891
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [Acids results in increased expression of IL6 mRNA] decreases reaction
/ increases expression
mRNA 19074641
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [Acids results in increased secretion of IL6 protein] decreases reaction
/ increases secretion
protein 19074641
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [cadmium sulfate results in increased expression of IL6 mRNA] decreases reaction
/ increases expression
mRNA 22142850
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [cadmium sulfate results in increased secretion of IL6 protein] decreases reaction
/ increases secretion
protein 22142850
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [IL6 protein results in increased expression of AR mRNA] decreases reaction
/ increases expression
protein 18676361
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [IL6 protein results in increased expression of AR protein] decreases reaction
/ increases expression
protein 18676361
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 mRNA] decreases reaction
/ increases expression
protein 18676361
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 protein] decreases reaction
/ increases expression
protein 18676361
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] decreases reaction
/ increases expression
mRNA 18209571
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] decreases reaction
/ increases secretion
protein 18357586
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL6 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 17151092
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin inhibits the reaction [TNF protein results in decreased expression of IL6 mRNA] decreases expression
/ decreases reaction
mRNA 17273796
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin results in decreased expression of IL6 mRNA decreases expression
mRNA 17999991
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Curcumin results in increased expression of IL6 mRNA increases expression
mRNA 18025290
21594647
D003474 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]] decreases reaction
/ increases secretion
protein 18357586
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased expression of and results in increased secretion of IL8 protein] decreases reaction
/ increases expression
/ increases secretion
protein 18413660
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [Acids results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
mRNA 19074641
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [Acids results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 19074641
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [cadmium sulfate results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
mRNA 22142850
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [cadmium sulfate results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 22142850
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [lauric acid results in increased expression of and results in increased secretion of IL8 protein] decreases reaction
/ increases expression
/ increases secretion
protein 18413660
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [Neurotensin results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
mRNA 17000667
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [Neurotensin results in increased expression of IL8 protein] decreases reaction
/ increases expression
protein 17000667
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [Shiga Toxin results in increased expression of IL8 protein] decreases reaction
/ increases expression
protein 16819191
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL8 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 17151092
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [TNF protein results in decreased expression of IL8 mRNA] decreases expression
/ decreases reaction
mRNA 17273796
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [TNF protein results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
mRNA 17666914
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin inhibits the reaction [TNF protein results in increased expression of IL8 protein] decreases reaction
/ increases expression
protein 17666914
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin results in decreased expression of and results in decreased secretion of IL8 protein decreases expression
/ decreases secretion
protein 12216086
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Curcumin results in decreased expression of IL8 protein decreases expression
protein 18226269
D003474 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of IL8 protein] decreases expression
/ increases reaction
protein 18226269
D003474 51141 INSIG2
insulin induced gene 2 Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA] decreases expression
/ decreases reaction
protein 18704882
D003474 3684 ITGAM
CD11B
CR3A
MAC-1
MAC1A
MO1A
SLEB6
integrin, alpha M (complement component 3 receptor 3 subunit) Calcitriol promotes the reaction [Curcumin results in increased expression of ITGAM] increases expression
/ increases reaction
9112257
D003474 3684 ITGAM
CD11B
CR3A
MAC-1
MAC1A
MO1A
SLEB6
integrin, alpha M (complement component 3 receptor 3 subunit) Curcumin results in increased expression of ITGAM increases expression
9112257
D003474 3684 ITGAM
CD11B
CR3A
MAC-1
MAC1A
MO1A
SLEB6
integrin, alpha M (complement component 3 receptor 3 subunit) Tretinoin promotes the reaction [Curcumin results in increased expression of ITGAM] increases expression
/ increases reaction
9112257
D003474 3688 ITGB1
CD29
FNRB
GPIIA
MDF2
MSK12
VLA-BETA
VLAB
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) Curcumin inhibits the reaction [IL1B protein results in decreased expression of ITGB1 protein] decreases expression
/ decreases reaction
protein 17291458
D003474 3688 ITGB1
CD29
FNRB
GPIIA
MDF2
MSK12
VLA-BETA
VLAB
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) Curcumin results in increased expression of ITGB1 protein increases expression
protein 17291458
D003474 3713 IVL
involucrin Curcumin inhibits the reaction [MAP3K1 protein results in increased expression of IVL mRNA] decreases reaction
/ increases expression
mRNA 17148446
D003474 3713 IVL
involucrin Curcumin inhibits the reaction [PRKCD protein results in increased expression of IVL mRNA] decreases reaction
/ increases expression
mRNA 17148446
D003474 3713 IVL
involucrin Curcumin inhibits the reaction [PRKCE protein results in increased expression of IVL mRNA] decreases reaction
/ increases expression
mRNA 17148446
D003474 3713 IVL
involucrin Curcumin inhibits the reaction [PRKCH protein results in increased expression of IVL mRNA] decreases reaction
/ increases expression
mRNA 17148446
D003474 3713 IVL
involucrin Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IVL mRNA] decreases reaction
/ increases expression
mRNA 17148446
D003474 3717 JAK2
JTK10
THCYT3
Janus kinase 2 (EC:2.7.10.2) Curcumin results in decreased expression of JAK2 protein decreases expression
protein 16959222
D003474 3718 JAK3
JAK-3
JAK3_HUMAN
JAKL
L-JAK
LJAK
Janus kinase 3 (EC:2.7.10.2) Curcumin results in decreased activity of JAK3 protein decreases activity
protein 16932349
D003474 126306 JSRP1
JP-45
JP45
junctional sarcoplasmic reticulum protein 1 Curcumin results in decreased expression of JSRP1 mRNA decreases expression
mRNA 17198877
D003474 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein] decreases reaction
/ increases activity
/ increases expression
protein 18628248
D003474 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein] decreases reaction
/ increases expression
protein 17148446
D003474 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene Curcumin results in decreased activity of JUN protein decreases activity
protein 17596214
D003474 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene Curcumin results in decreased phosphorylation of JUN protein decreases phosphorylation
protein 17596214
D003474 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene Curcumin results in increased expression of JUN mRNA increases expression
mRNA 15713895
D003474 3726 JUNB
AP-1
jun B proto-oncogene benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]] decreases reaction
/ increases expression
protein 17148446
D003474 3726 JUNB
AP-1
jun B proto-oncogene Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]] affects binding
/ decreases reaction
/ increases reaction
protein 17148446
D003474 3726 JUNB
AP-1
jun B proto-oncogene Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein] decreases reaction
/ increases expression
protein 17148446
D003474 3726 JUNB
AP-1
jun B proto-oncogene Curcumin results in increased ubiquitination of JUNB protein increases ubiquitination
protein 17148446
D003474 3727 JUND
AP-1
jun D proto-oncogene Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUND protein] decreases reaction
/ increases expression
protein 17148446
D003474 10242 KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2 Curcumin results in decreased expression of KCNMB2 mRNA decreases expression
mRNA 17198877
D003474 3791 KDR
CD309
FLK1
VEGFR
VEGFR2
kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1) Curcumin affects the expression of KDR mRNA affects expression
mRNA 17960570
D003474 7071 KLF10
EGR-alpha
EGRA
TIEG
TIEG1
Kruppel-like factor 10 Curcumin results in decreased expression of KLF10 mRNA decreases expression
mRNA 17999991
D003474 1316 KLF6
BCD1
CBA1
COPEB
CPBP
GBF
PAC1
ST12
ZF9
Kruppel-like factor 6 Curcumin results in increased expression of KLF6 mRNA increases expression
mRNA 15713895
D003474 9903 KLHL21
kelch-like family member 21 Curcumin results in increased expression of KLHL21 mRNA increases expression
mRNA 17198877
D003474 54800 KLHL24
DRE1
KRIP6
kelch-like family member 24 Curcumin results in decreased expression of KLHL24 mRNA decreases expression
mRNA 17198877
D003474 3817 KLK2
KLK2A2
hGK-1
hK2
kallikrein-related peptidase 2 (EC:3.4.21.35) Curcumin results in decreased expression of KLK2 mRNA decreases expression
mRNA 18719366
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [AR protein results in increased expression of KLK3 mRNA] decreases reaction
/ increases expression
mRNA 22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
enhancer 22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
enhancer 22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [EP300 protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
enhancer 22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
enhancer 22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to KLK3 enhancer]] affects binding
/ decreases reaction
/ increases reaction
enhancer 22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [GATA2 protein results in increased expression of KLK3 mRNA] decreases reaction
/ increases expression
mRNA 22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 mRNA] decreases reaction
/ increases expression
mRNA 18676361
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 protein] decreases reaction
/ increases expression
protein 18676361
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA] decreases reaction
/ increases expression
mRNA 18676361
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin inhibits the reaction [Metribolone results in increased expression of KLK3 protein] decreases reaction
/ increases expression
protein 18676361
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin results in decreased expression of and results in decreased secretion of KLK3 protein decreases expression
/ decreases secretion
protein 18676361
18719366
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin results in decreased expression of KLK3 mRNA decreases expression
mRNA 18676361
18719366
22258452
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Curcumin results in decreased expression of KLK3 protein decreases expression
protein 12497104
21134073
D003474 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) trichostatin A inhibits the reaction [Curcumin results in decreased expression of KLK3 mRNA] decreases expression
/ decreases reaction
mRNA 22258452
D003474 3845 KRAS
C-K-RAS
CFC2
K-RAS2A
K-RAS2B
K-RAS4A
K-RAS4B
KI-RAS
KRAS1
KRAS2
NS
NS3
RASK2
Kirsten rat sarcoma viral oncogene homolog Curcumin analog results in decreased expression of KRAS mRNA decreases expression
mRNA 17041101
D003474 3845 KRAS
C-K-RAS
CFC2
K-RAS2A
K-RAS2B
K-RAS4A
K-RAS4B
KI-RAS
KRAS1
KRAS2
NS
NS3
RASK2
Kirsten rat sarcoma viral oncogene homolog Curcumin results in decreased expression of KRAS mRNA decreases expression
mRNA 17041101
D003474 81872 KRTAP2-1
KAP2.1A
KRTAP2.1A
keratin associated protein 2-1 Curcumin results in decreased expression of KRTAP2-1 mRNA decreases expression
mRNA 17999991
D003474 8942 KYNU
kynureninase (EC:3.7.1.3) Curcumin results in increased expression of KYNU mRNA increases expression
mRNA 18421014
D003474 3937 LCP2
SLP-76
SLP76
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) Curcumin results in increased expression of LCP2 mRNA increases expression
mRNA 17198877
D003474 3949 LDLR
FH
FHC
LDLCQ2
low density lipoprotein receptor Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA] decreases expression
/ decreases reaction
mRNA 18704882
D003474 3949 LDLR
FH
FHC
LDLCQ2
low density lipoprotein receptor Curcumin results in increased expression of and results in increased activity of LDLR protein increases activity
/ increases expression
protein 18704882
D003474 3949 LDLR
FH
FHC
LDLCQ2
low density lipoprotein receptor Curcumin results in increased expression of LDLR mRNA increases expression
mRNA 16713233
16963807
18704882
D003474 3949 LDLR
FH
FHC
LDLCQ2
low density lipoprotein receptor Curcumin results in increased expression of LDLR protein increases expression
protein 16963807
D003474 3980 LIG3
LIG2
ligase III, DNA, ATP-dependent (EC:6.5.1.1) Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG3 mRNA] decreases expression
/ decreases reaction
mRNA 21332098
D003474 3980 LIG3
LIG2
ligase III, DNA, ATP-dependent (EC:6.5.1.1) Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG3 protein] decreases expression
/ decreases reaction
protein 21332098
D003474 3981 LIG4
ligase IV, DNA, ATP-dependent (EC:6.5.1.1) Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG4 mRNA] decreases expression
/ decreases reaction
mRNA 21332098
D003474 3981 LIG4
ligase IV, DNA, ATP-dependent (EC:6.5.1.1) Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG4 protein] decreases expression
/ decreases reaction
protein 21332098
D003474 1902 LPAR1
EDG2
GPR26
Gpcr26
LPA1
Mrec1.3
VZG1
edg-2
rec.1.3
vzg-1
lysophosphatidic acid receptor 1 Curcumin results in decreased expression of LPAR1 mRNA decreases expression
mRNA 17999991
D003474 4033 LRMP
JAW1
lymphoid-restricted membrane protein Curcumin results in decreased expression of LRMP mRNA decreases expression
mRNA 17198877
D003474 54674 LRRN3
FIGLER5
NLRR-3
NLRR3
leucine rich repeat neuronal 3 Curcumin results in increased expression of LRRN3 mRNA increases expression
mRNA 17198877
D003474 4049 LTA
LT
TNFB
TNFSF1
lymphotoxin alpha Curcumin results in decreased expression of LTA mRNA decreases expression
mRNA 16101141
D003474 4049 LTA
LT
TNFB
TNFSF1
lymphotoxin alpha Curcumin results in increased expression of LTA mRNA increases expression
mRNA 17198877
D003474 4050 LTB
TNFC
TNFSF3
p33
lymphotoxin beta (TNF superfamily, member 3) Curcumin results in increased expression of LTB mRNA increases expression
mRNA 17198877
D003474 5604 MAP2K1
CFC3
MAPKK1
MEK1
MKK1
PRKMK1
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] decreases reaction
/ increases expression
protein 21810436
D003474 5604 MAP2K1
CFC3
MAPKK1
MEK1
MKK1
PRKMK1
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5604 MAP2K1
CFC3
MAPKK1
MEK1
MKK1
PRKMK1
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5604 MAP2K1
CFC3
MAPKK1
MEK1
MKK1
PRKMK1
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) MAP2K1 results in decreased susceptibility to [Curcumin co-treated with Mitomycin] affects cotreatment
/ decreases response to substance
21810436
D003474 5605 MAP2K2
CFC4
MAPKK2
MEK2
MKK2
PRKMK2
mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] decreases reaction
/ increases expression
protein 21810436
D003474 5605 MAP2K2
CFC4
MAPKK2
MEK2
MKK2
PRKMK2
mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5605 MAP2K2
CFC4
MAPKK2
MEK2
MKK2
PRKMK2
mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5605 MAP2K2
CFC4
MAPKK2
MEK2
MKK2
PRKMK2
mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) MAP2K2 results in decreased susceptibility to [Curcumin co-treated with Mitomycin] affects cotreatment
/ decreases response to substance
21810436
D003474 5606 MAP2K3
MAPKK3
MEK3
MKK3
PRKMK3
SAPKK-2
SAPKK2
mitogen-activated protein kinase kinase 3 (EC:2.7.12.2) Curcumin results in increased expression of MAP2K3 mRNA increases expression
mRNA 15713895
D003474 6416 MAP2K4
JNKK
JNKK1
MAPKK4
MEK4
MKK4
PRKMK4
SAPKK-1
SAPKK1
SEK1
SERK1
SKK1
mitogen-activated protein kinase kinase 4 (EC:2.7.12.2) Curcumin results in decreased expression of MAP2K4 mRNA decreases expression
mRNA 15713895
D003474 4214 MAP3K1
MAPKKK1
MEKK
MEKK_1
MEKK1
SRXY6
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase (EC:2.7.11.25) Curcumin inhibits the reaction [MAP3K1 protein results in increased expression of IVL mRNA] decreases reaction
/ increases expression
protein 17148446
D003474 4214 MAP3K1
MAPKKK1
MEKK
MEKK_1
MEKK1
SRXY6
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase (EC:2.7.11.25) Curcumin results in decreased expression of MAP3K1 mRNA decreases expression
mRNA 15713895
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 18357586
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) arsenic trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK1 protein] increases activity
/ increases phosphorylation
/ increases reaction
protein 20605902
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of MAPK1 protein] decreases phosphorylation
/ increases reaction
protein 19383353
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin inhibits the reaction [Acids results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 19074641
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 22142850
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 18214481
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 20727180
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin results in decreased activity of MAPK1 protein decreases activity
protein 21493726
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) [Curcumin results in decreased activity of MAPK1 protein] which results in increased susceptibility to Cisplatin decreases activity
/ increases response to substance
protein 21493726
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin results in decreased expression of MAPK1 protein decreases expression
protein 18555241
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin results in decreased phosphorylation of MAPK1 protein decreases phosphorylation
protein 19383353
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin results in increased phosphorylation of and results in increased activity of MAPK1 protein increases activity
/ increases phosphorylation
protein 18357586
20605902
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Curcumin results in increased phosphorylation of MAPK1 protein increases phosphorylation
protein 18316600
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) MAPK1 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA] affects reaction
/ increases expression
protein 18316600
D003474 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) U 0126 promotes the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]] decreases reaction
/ increases phosphorylation
/ increases reaction
protein 21810436
D003474 6300 MAPK12
ERK3
ERK6
P38GAMMA
PRKM12
SAPK-3
SAPK3
mitogen-activated protein kinase 12 (EC:2.7.11.24) Curcumin results in increased activity of MAPK12 protein increases activity
protein 21594647
D003474 1432 MAPK14
CSBP
CSBP1
CSBP2
CSPB1
EXIP
Mxi2
PRKM14
PRKM15
RK
SAPK2A
p38
p38ALPHA
mitogen-activated protein kinase 14 (EC:2.7.11.24) Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein] affects cotreatment
/ decreases reaction
/ increases phosphorylation
protein 17151092
D003474 1432 MAPK14
CSBP
CSBP1
CSBP2
CSPB1
EXIP
Mxi2
PRKM14
PRKM15
RK
SAPK2A
p38
p38ALPHA
mitogen-activated protein kinase 14 (EC:2.7.11.24) MAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein] affects reaction
/ increases expression
protein 18357586
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 18357586
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) arsenic trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK3 protein] increases activity
/ increases phosphorylation
/ increases reaction
protein 20605902
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of MAPK3 protein] decreases phosphorylation
/ increases reaction
protein 19383353
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin inhibits the reaction [Acids results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 19074641
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 22142850
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 18214481
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 21810436
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 20727180
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin results in decreased activity of MAPK3 protein decreases activity
protein 21493726
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) [Curcumin results in decreased activity of MAPK3 protein] which results in increased susceptibility to Cisplatin decreases activity
/ increases response to substance
protein 21493726
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin results in decreased expression of MAPK3 protein decreases expression
protein 18555241
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin results in decreased phosphorylation of MAPK3 protein decreases phosphorylation
protein 19383353
D003474 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Curcumin results in increased phosphorylation of and results in increased activity of MAPK3 protein increases activity
/ increases phosphorylation