KNApSAcK Metabolite C00001182
Metabolite
KNApSAcK Entry
| id | C00001182 |
|---|---|
| Name | Formic acid |
| CAS RN | 64-18-6 |
| Standard InChI | InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3) |
| Standard InChI (Main Layer) | InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 7874 |
Link
ChEMBL
| By standard InChI | CHEMBL116736 |
|---|---|
| By standard InChI Main Layer | CHEMBL116736 |
KEGG
| By LinkDB | C00058 |
|---|
CTD
| By CAS RN | C030544 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Enterobacteriaceae | 1 |
| Urticaceae | 1 |
List (2)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Escherichia coli | 562 | Enterobacteriaceae | Bacteria | |
| Urtica dioica | 3501 | Urticaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
CTD interaction (8)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C030544 | 1356 |
CP
CP-2 |
ceruloplasmin (ferroxidase) (EC:1.16.3.1) | formic acid inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] |
affects binding
/ decreases reaction / increases reaction |
protein |
16756764
|
| C030544 | 3064 |
HTT
HD IT15 |
huntingtin | formic acid inhibits the reaction [HTT protein binds to HTT protein] |
affects binding
/ decreases reaction |
protein |
11032734
|
| C030544 | 4953 |
ODC1
ODC |
ornithine decarboxylase 1 (EC:4.1.1.17) | formic acid results in decreased activity of ODC1 protein |
decreases activity
|
protein |
3986791
|
| C030544 | 5172 |
SLC26A4
DFNB4 EVA PDS TDH2B |
solute carrier family 26 (anion exchanger), member 4 | SLC26A4 protein results in increased transport of formic acid |
increases transport
|
protein |
10644529
|
| C030544 | 6647 |
SOD1
ALS ALS1 IPOA SOD hSod1 homodimer |
superoxide dismutase 1, soluble (EC:1.15.1.1) | formic acid promotes the reaction [Copper binds to SOD1 protein] |
affects binding
/ increases reaction |
protein |
15620721
|
| C030544 | 6647 |
SOD1
ALS ALS1 IPOA SOD hSod1 homodimer |
superoxide dismutase 1, soluble (EC:1.15.1.1) | formic acid promotes the reaction [SOD1 protein results in increased metabolism of Hydrogen Peroxide] |
increases metabolic processing
/ increases reaction |
protein |
19243126
|
| C030544 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | formic acid inhibits the reaction [sodium bichromate results in increased expression of TP53 protein] |
decreases reaction
/ increases expression |
protein |
10942736
|
| C030544 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | formic acid inhibits the reaction [Potassium Dichromate results in increased expression of VEGFA protein] |
decreases reaction
/ increases expression |
protein |
12213806
|