Urtica dioica

• Index
• Plant Species
• Natural Activity
• Metabolite list (8)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Urtica dioica
Genus	Urtica
Family	Urticaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Urtica dioica
Linked NCBI taxonomy ID	3501
Linked level	species

Family

Family in NCBI taxonomy	Urticaceae
ID	3499

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Natural Activity

List (62)

Species	Activity
Urtica dioica L.	5-Lipoxygenase Inhibitor
Urtica dioica L.	Analgesic
Urtica dioica L.	Anesthetic
Urtica dioica L.	Anti-HIV
Urtica dioica L.	Antiadrenaline
Urtica dioica L.	Antiallergic
Urtica dioica L.	Antiaromatase
Urtica dioica L.	Antiarthritic
Urtica dioica L.	Antiasthmatic
Urtica dioica L.	Antibacterial
Urtica dioica L.	Anticancer
Urtica dioica L.	Anticomplementary
Urtica dioica L.	Anticonvulsant
Urtica dioica L.	Antiedemic
Urtica dioica L.	Antiexudative
Urtica dioica L.	Antihemorrhagic
Urtica dioica L.	Antihidrotic
Urtica dioica L.	Antihistaminic
Urtica dioica L.	Antiinflammatory
Urtica dioica L.	Antileukotriene
Urtica dioica L.	Antiprostatitic
Urtica dioica L.	Antipyretic
Urtica dioica L.	Antirheumatic
Urtica dioica L.	Antiseptic
Urtica dioica L.	Antispasmodic
Urtica dioica L.	Antitumor
Urtica dioica L.	Antiviral
Urtica dioica L.	Aphrodisiac
Urtica dioica L.	Aquaretic
Urtica dioica L.	Aromatase Inhibitor
Urtica dioica L.	Astringent
Urtica dioica L.	Bitter
Urtica dioica L.	Bleeding
Urtica dioica L.	Bradycardic
Urtica dioica L.	CNS Depressant
Urtica dioica L.	Cyclooxygenase Inhibitor
Urtica dioica L.	Cytotoxic
Urtica dioica L.	Depurative
Urtica dioica L.	Diuretic
Urtica dioica L.	Elastase Inhibitor
Urtica dioica L.	Emmenagogue
Urtica dioica L.	Expectorant
Urtica dioica L.	Fungicide
Urtica dioica L.	Hematogenic
Urtica dioica L.	Hemostat
Urtica dioica L.	Histaminic
Urtica dioica L.	Hyperglycemic
Urtica dioica L.	Hypoglycemic
Urtica dioica L.	Hypotensive
Urtica dioica L.	Inteferonigenic
Urtica dioica L.	Lactagogue
Urtica dioica L.	Laxative
Urtica dioica L.	Litholytic
Urtica dioica L.	Mitogenic
Urtica dioica L.	Myorelaxant
Urtica dioica L.	Pancreatonic
Urtica dioica L.	Rubefacient
Urtica dioica L.	Tonic
Urtica dioica L.	Uterotonic
Urtica dioica L.	Vasoconstrictor
Urtica dioica L.	Vermifuge
Urtica dioica L.	Vulnerary

Metabolite list (8)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00007204	Isolariciresinol / (+)-Isolariciresinol	CHEMBL399512 CHEMBL1760593	C060284	2 / 1 / 1		No. 406
C00002591	(-)-Cubebin / beta-Cubebin / (-)-beta-Cubebin / (8R,8'R,9S)-Cubebin	CHEMBL182001 CHEMBL399831	C433065	2 / 1 / 1	0 / 2	No. 629	No. 21
C00001429	Serotonin / Enteramin / Enteramine / DS substance / Thrombotonin / Thrombocytin / 5-Hydroxytryptamine	CHEMBL39 CHEMBL1628597	D012701	78 / 35 / 22	32 / 40	No. 1910	No. 4
C00002685	Acetophenone	CHEMBL274467	C038699	2 / 0 / 0	2 / 0	No. 2578	No. 9
C00001414	Histamine	CHEMBL90	D006632	30 / 21 / 20	63 / 40	No. 4250
C00001182	Formic acid	CHEMBL116736	C030544		7 / 1	No. 7874

Human Protein / Gene in interactions

95 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000604 C00001414 C00001429 C00002591 C00007204	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000604 C00001414 C00001429 C00002591 C00007204	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001414 C00001429	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00001414 C00001429	1 / 1
O15244	Solute carrier family 22 member 2	Drug uniporter	C00001414 C00001429	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001414 C00001429	2 / 0
P07451	Carbonic anhydrase 3	Lyase	C00001414 C00001429	0 / 0
O75751	Solute carrier family 22 member 3	Unclassified protein	C00001414 C00001429	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001414 C00001429	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00001429 C00007190	0 / 3
Q16790	Carbonic anhydrase 9	Lyase	C00001414 C00001429	0 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001414 C00001429	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00001414 C00001429	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00001414 C00001429	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00001414 C00001429	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00001414 C00001429	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00001414 C00001429	1 / 2
Q9ULX7	Carbonic anhydrase 14	Lyase	C00001414 C00001429	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00001414 C00001429	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001414 C00001429	0 / 1
P00918	Carbonic anhydrase 2	Lyase	C00001414 C00001429	1 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00001414 C00001429	3 / 2
P14679	Tyrosinase	Oxidoreductase	C00001429	4 / 2
P25021	Histamine H2 receptor	Histamine receptor	C00001414	0 / 0
P28222	5-hydroxytryptamine receptor 1B	Serotonin receptor	C00001429	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00001414	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00001429	0 / 0
P47898	5-hydroxytryptamine receptor 5A	Serotonin receptor	C00001429	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00001414	11 / 10
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00001429	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00001429	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00001429	0 / 0
O15245	Solute carrier family 22 member 1	Drug uniporter	C00001414	0 / 0
P05164	Myeloperoxidase	Enzyme	C00001429	1 / 2
P28566	5-hydroxytryptamine receptor 1E	Serotonin receptor	C00001429	0 / 0
Q13464	Rho-associated protein kinase 1	Rock	C00002685	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00007190	0 / 0
P49286	Melatonin receptor type 1B	Melatonin receptor	C00001429	0 / 1
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001429	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00001429	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00001429	1 / 0
P46098	5-hydroxytryptamine receptor 3A	NS	C00001429	0 / 0
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00001429	0 / 0
Q9Y5N1	Histamine H3 receptor	Histamine receptor	C00001414	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00002685	0 / 0
Q9H3N8	Histamine H4 receptor	Histamine receptor	C00001414	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001414	0 / 0
P23415	Glycine receptor subunit alpha-1	GLR alpha	C00001429	1 / 1
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001429	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00007190	5 / 3
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00001429	0 / 0
P36544	Neuronal acetylcholine receptor subunit alpha-7	CHRN alpha	C00001429	0 / 0
P48039	Melatonin receptor type 1A	Melatonin receptor	C00001429	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00001429	0 / 0
Q13639	5-hydroxytryptamine receptor 4	Serotonin receptor	C00001429	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00007190	0 / 0
P06133	UDP-glucuronosyltransferase 2B4	Enzyme	C00001429	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00001429	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001429	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001429	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001429	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00007190	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001414	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00001429	5 / 1
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00001429	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00001429	1 / 0
P28221	5-hydroxytryptamine receptor 1D	Serotonin receptor	C00001429	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00007190	0 / 0
P30939	5-hydroxytryptamine receptor 1F	Serotonin receptor	C00001429	0 / 0
Q7Z2W7	Transient receptor potential cation channel subfamily M member 8	Unclassified protein	C00001429	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00001414	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00001429	0 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00001429	1 / 0
Q9UN88	Gamma-aminobutyric acid receptor subunit theta	GABA-A theta	C00001429	0 / 0
P28472	Gamma-aminobutyric acid receptor subunit beta-3	GABA-A beta	C00001429	1 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00001429	1 / 1
P48169	Gamma-aminobutyric acid receptor subunit alpha-4	GABA-A alpha	C00001429	0 / 0
O14764	Gamma-aminobutyric acid receptor subunit delta	GABA-A delta	C00001429	1 / 1
P31644	Gamma-aminobutyric acid receptor subunit alpha-5	GABA-A alpha	C00001429	0 / 0
Q99928	Gamma-aminobutyric acid receptor subunit gamma-3	GABA-A gamma	C00001429	0 / 0
P78334	Gamma-aminobutyric acid receptor subunit epsilon	GABA-A epsilon	C00001429	0 / 0
Q8N1C3	Gamma-aminobutyric acid receptor subunit gamma-1	GABA-A gamma	C00001429	0 / 0
P34903	Gamma-aminobutyric acid receptor subunit alpha-3	GABA-A alpha	C00001429	0 / 0
O00591	Gamma-aminobutyric acid receptor subunit pi	GABA-A pi	C00001429	0 / 0
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00001429	0 / 0
P18507	Gamma-aminobutyric acid receptor subunit gamma-2	GABA-A gamma	C00001429	4 / 2
P18505	Gamma-aminobutyric acid receptor subunit beta-1	GABA-A beta	C00001429	0 / 0
Q16445	Gamma-aminobutyric acid receptor subunit alpha-6	GABA-A alpha	C00001429	0 / 0
P47869	Gamma-aminobutyric acid receptor subunit alpha-2	GABA-A alpha	C00001429	1 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00001429	3 / 0
Q8WXA8	5-hydroxytryptamine receptor 3C	NS	C00001429	0 / 0
Q70Z44	5-hydroxytryptamine receptor 3D	NS	C00001429	0 / 0
O95264	5-hydroxytryptamine receptor 3B	NS	C00001429	0 / 0
A5X5Y0	5-hydroxytryptamine receptor 3E	NS	C00001429	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00007190	0 / 0

99 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
3593	IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	C00001414 C00001429
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001414 C00001429
6571	SLC18A2, SVAT, SVMT, VAT2, VMAT2	solute carrier family 18 (vesicular monoamine transporter), member 2	C00001414 C00001429
6570	SLC18A1, CGAT, VAT1, VMAT1	solute carrier family 18 (vesicular monoamine transporter), member 1	C00001414 C00001429
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001414 C00001429
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001414 C00001429
847	CAT	catalase (EC:1.11.1.6)	C00001429
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00002685
250	ALPP, ALP, PALP, PLAP, PLAP-1	alkaline phosphatase, placental (EC:3.1.3.1)	C00002685
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00001414
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001414
240	ALOX5, 5-LO, 5-LOX, 5LPG, LOG5	arachidonate 5-lipoxygenase (EC:1.13.11.34)	C00001414
241	ALOX5AP, FLAP	arachidonate 5-lipoxygenase-activating protein	C00001414
26	AOC1, ABP, ABP1, DAO, DAO1, KAO	amine oxidase, copper containing 1 (EC:1.4.3.22)	C00001414
362	AQP5, AQP-5, PPKB	aquaporin 5	C00001414
613	BCR, ALL, BCR1, CML, D22S11, D22S662, PHL	breakpoint cluster region (EC:2.7.11.1)	C00001414
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00001414
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00001414
929	CD14	CD14 molecule	C00001414
958	CD40, Bp50, CDW40, TNFRSF5, p50	CD40 molecule, TNF receptor superfamily member 5	C00001414
941	CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7	CD80 molecule	C00001414
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00001414
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001414
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00001414
1179	CLCA1, CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1	chloride channel accessory 1	C00001414
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00001414
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00001414
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00001414
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00001414
2205	FCER1A, FCE1A, FcERI	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	C00001414
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00001414
2990	GUSB, BG, MPS7	glucuronidase, beta (EC:3.2.1.31)	C00001414
3067	HDC	histidine decarboxylase (EC:4.1.1.22)	C00001414
3176	HNMT, HMT, HNMT-S1, HNMT-S2	histamine N-methyltransferase (EC:2.1.1.8)	C00001414
3269	HRH1, H1-R, hisH1	histamine receptor H1	C00001414
3274	HRH2, H2R	histamine receptor H2	C00001414
11255	HRH3, GPCR97, HH3R	histamine receptor H3	C00001414
59340	HRH4, AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R	histamine receptor H4	C00001414
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00001414
3458	IFNG, IFG, IFI	interferon, gamma	C00001414
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00001414
3592	IL12A, CLMF, IL-12A, NFSK, NKSF1, P35	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	C00001414
1356	CP, CP-2	ceruloplasmin (ferroxidase) (EC:1.16.3.1)	C00001182
3603	IL16, LCF, NIL16, PRIL16, prIL-16	interleukin 16	C00001414
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00001414
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00001414
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00001182
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001182
3785	KCNQ2, BFNC, BFNS1, EBN, EBN1, EIEE7, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1	potassium voltage-gated channel, KQT-like subfamily, member 2	C00001414
3786	KCNQ3, BFNC2, EBN2, KV7.3	potassium voltage-gated channel, KQT-like subfamily, member 3	C00001414
4056	LTC4S	leukotriene C4 synthase (EC:4.4.1.20)	C00001414
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00001414
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00001414
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00001414
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00001414
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00001414
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001414
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00001414
5321	PLA2G4A, PLA2G4, cPLA2-alpha	phospholipase A2, group IVA (cytosolic, calcium-dependent) (EC:3.1.1.5 3.1.1.4)	C00001414
5562	PRKAA1, AMPK, AMPKa1	protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)	C00001414
5563	PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA	protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31)	C00001414
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001414
5788	PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200	protein tyrosine phosphatase, receptor type, C (EC:3.1.3.48)	C00001414
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001414
5172	SLC26A4, DFNB4, EVA, PDS, TDH2B	solute carrier family 26 (anion exchanger), member 4	C00001182
4953	ODC1, ODC	ornithine decarboxylase 1 (EC:4.1.1.17)	C00001182
6581	SLC22A3, EMT, EMTH, OCT3	solute carrier family 22 (organic cation transporter), member 3	C00001414
6794	STK11, LKB1, PJS, hLKB1	serine/threonine kinase 11 (EC:2.7.11.1)	C00001414
6863	TAC1, Hs.2563, NK2, NKNA, NPK, TAC2	tachykinin, precursor 1	C00001414
7097	TLR2, CD282, TIL4	toll-like receptor 2	C00001414
3064	HTT, HD, IT15	huntingtin	C00001182
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00001414
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00001182
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00001429
2597	GAPDH, G3PD, GAPD	glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)	C00001429
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00001429
3352	HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	C00001429
3356	HTR2A, 5-HT2A, HTR2	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	C00001429
3359	HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	C00001429
9177	HTR3B, 5-HT3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	C00001429
3363	HTR7, 5-HT7	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	C00001429
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00001429
3690	ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	C00001429
4128	MAOA, MAO-A	monoamine oxidase A (EC:1.4.3.4)	C00001429
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00001429
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001429
85413	SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1	solute carrier family 22 (organic cation/carnitine transporter), member 16	C00001429
6530	SLC6A2, NAT1, NET, NET1, SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 2	C00001429
6531	SLC6A3, DAT, DAT1, PKDYS	solute carrier family 6 (neurotransmitter transporter), member 3	C00001429
6532	SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT	solute carrier family 6 (neurotransmitter transporter), member 4	C00001429
6814	STXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C	syntaxin binding protein 3	C00001429
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00001429
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00001429
134864	TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1	trace amine associated receptor 1	C00001429
7166	TPH1, TPRH, TRPH, TPH	tryptophan hydroxylase 1 (EC:1.14.16.4)	C00001429
8989	TRPA1, ANKTM1, FEPS	transient receptor potential cation channel, subfamily A, member 1	C00001429
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00001429
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00001429

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Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions