KCF-S cluster No. 629 (13 metabolites)

Corresponding Phytochemical cluster No. 21

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (13)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Magnoliophyta	31
Spermatophyta	25
asterids	21
rosids	19
eudicotyledons	4
Embryophyta	1

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Cumulative family count (Top 20)

class name	count
Cupressaceae	12
Aristolochiaceae	11
Piperaceae	10
Pinaceae	8
Myristicaceae	7
Phyllanthaceae	6
Acanthaceae	6
Taxaceae	4
Asteraceae	4
Rutaceae	4
Rubiaceae	3
Schisandraceae	2
Araliaceae	2
Cynomoriaceae	1
Fabaceae	1
Betulaceae	1
Ranunculaceae	1
Araucariaceae	1
Gentianaceae	1
Thymelaeaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Lignans	2

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metabolites link (3)

br08003 Category	KEGG ID	KNApSAcK ID
Lignans	C10558	C00002599
Lignans	C10627	C00002608
Lignans	C10558	C00039028

Metabolite list (13)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002591	(-)-Cubebin / beta-Cubebin / (-)-beta-Cubebin / (8R,8'R,9S)-Cubebin	CHEMBL182001 CHEMBL399831	C433065	2 / 1 / 1	0 / 2
C00002599	(-)-Dihydrocubebin	CHEMBL486597 CHEMBL1477391	C011228	4 / 8 / 4
C00002608	Hinokinin / Hinoquinin / (-)-Hinokinin / (-)-Hinoquinin	CHEMBL180970 CHEMBL182073 CHEMBL242011	C475934	2 / 1 / 1
C00015304	3,4 / 3',4'-Bismethylenedioxybibenzyl
C00032678	8'beta-Hydroxyhinokinin / (-)-8'beta-Hydroxyhinokinin
C00036311	(+)-Hinokinin	CHEMBL180970 CHEMBL182073 CHEMBL242011		2 / 1 / 1
C00036711	alpha-Cubebin / (-)-alpha-Cubebin	CHEMBL182001 CHEMBL399831		2 / 1 / 1
C00036801	beta-Methylcubebin	CHEMBL520915		2 / 1 / 1
C00037251	Heliobuphthalmin lactone	CHEMBL180970 CHEMBL182073 CHEMBL242011		2 / 1 / 1
C00039028	Dihydrocubebin / (-)-Dihydrocubebin	CHEMBL486597 CHEMBL1477391	C011228	4 / 8 / 4
C00042458	Dehydroxycubebin / (-)-Dehydroxycubebin	CHEMBL487394
C00042729	Meridinol
C00045652	Aristelegin A / (-)-Aristelegin A

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002591 C00002599 C00002608 C00036311 C00036711 C00036801 C00037251 C00039028	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002591 C00002599 C00002608 C00036311 C00036711 C00036801 C00037251 C00039028	0 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002599 C00039028	7 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002599 C00039028	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions