PCIDB

KNApSAcK Metabolite C00002599

Metabolite

KNApSAcK Entry

id C00002599
Name (-)-Dihydrocubebin
CAS RN 24563-03-9
Standard InChI InChI=1S/C20H22O6/c21-9-15(5-13-1-3-17-19(7-13)25-11-23-17)16(10-22)6-14-2-4-18-20(8-14)26-12-24-18/h1-4,7-8,15-16,21-22H,5-6,9-12H2/t15-,16-/m0/s1
Standard InChI (Main Layer) InChI=1S/C20H22O6/c21-9-15(5-13-1-3-17-19(7-13)25-11-23-17)16(10-22)6-14-2-4-18-20(8-14)26-12-24-18/h1-4,7-8,15-16,21-22H,5-6,9-12H2

Cluster

Phytochemical cluster No. 21
KCF-S cluster No. 629

Link

ChEMBL

By standard InChI CHEMBL486597
By standard InChI Main Layer CHEMBL486597 CHEMBL1477391

KEGG

By LinkDB C10558

CTD

By CAS RN C011228

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL486597 CHEMBL970954 (1)
1 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1477391 CHEMBL2114810 (1)
7 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL1477391 CHEMBL1738588 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL486597 CHEMBL970953 (1) CHEMBL1743432 (2)
0 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#608902 Drug metabolism, poor, cyp2d6-related P10635
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (4)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)