Aristolochia pubescens
Species
KNApSAcK Entry
| Organism name | Aristolochia pubescens |
|---|---|
| Genus | Aristolochia |
| Family | Aristolochiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Aristolochia |
|---|---|
| Linked NCBI taxonomy ID | 12947 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Aristolochiaceae |
|---|---|
| ID | 16727 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Metabolite list (26)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00036281
|
(-)-Isocorydine
|
CHEMBL489525
CHEMBL1376826 |
14 / 7 / 10 | No. 20 | No. 4 |
|
||
|
C00000640
|
(+)-Eudesmin
|
CHEMBL519099
CHEMBL512865 CHEMBL523743 CHEMBL464352 CHEMBL1726879 |
C105875
|
2 / 0 / 0 | No. 38 | No. 21 |
|
|
|
C00023770
|
Sitosterol
/ Stigmasta-5,22-dien-3beta-ol / (24R)24-Ethylcholesta-5,22-dien-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00037102
|
ent-Kaur-15-en-17-ol
|
CHEMBL481119
|
C066409
|
No. 159 | No. 41 |
|
||
|
C00002611
|
Licarin A
/ (-)-Licarin A |
CHEMBL259731
CHEMBL463526 CHEMBL1732407 |
9 / 7 / 3 | No. 215 | No. 23 |
|
||
|
C00034356
|
Kusunokinin
/ (-)-Kusunokinin |
No. 223 | No. 21 |
|
||||
|
C00036847
|
Bursehernin
/ (-)-Bursehernin |
C023816
|
No. 223 | No. 21 |
|
|||
|
C00032731
|
Aristolochate II
|
CHEMBL602280
|
1 / 0 / 0 | No. 291 | No. 4 |
|
||
|
C00001526
|
Aristolochic acid I
/ Aristolochic acid A |
CHEMBL93353
|
C000228
|
13 / 11 / 12 | 21 / 10 | No. 291 | No. 4 |
|
|
C00032730
|
Aristolochate I
|
CHEMBL93353
|
13 / 11 / 12 | No. 291 | No. 4 |
|
||
|
C00032729
|
Aristolochate C
/ Aristolochate IIIa |
CHEMBL603494
|
1 / 0 / 0 | No. 291 | No. 4 |
|
||
|
C00027520
|
Aristolochic acid VIIa
/ 7-Hydroxyaristolochate A / 7-Hydroxyaristolochic acid / 7-Hydroxyaristolochic acid I / 7-Hydroxy-aristolochic acid A |
CHEMBL600828
|
1 / 0 / 0 | No. 291 | No. 4 |
|
||
|
C00032766
|
Aristolochate IVa
|
CHEMBL604748
|
3 / 0 / 0 | No. 291 | No. 4 |
|
||
|
C00025334
|
trans-Feruloyltyramine
/ N-trans-Feruloyltyramine / trans-N-Feruloyltyramine |
CHEMBL206555
CHEMBL451720 |
1 / 4 / 2 | No. 499 |
|
|||
|
C00000601
|
(+)-Sesamin
|
CHEMBL43469
CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861 |
C054125
|
20 / 24 / 15 | 0 / 5 | No. 621 | No. 21 |
|
|
C00002591
|
(-)-Cubebin
/ beta-Cubebin / (-)-beta-Cubebin / (8R,8'R,9S)-Cubebin |
CHEMBL182001
CHEMBL399831 |
C433065
|
2 / 1 / 1 | 0 / 2 | No. 629 | No. 21 |
|
|
C00002608
|
Hinokinin
/ Hinoquinin / (-)-Hinokinin / (-)-Hinoquinin |
CHEMBL180970
CHEMBL182073 CHEMBL242011 |
C475934
|
2 / 1 / 1 | No. 629 | No. 21 |
|
|
|
C00002599
|
(-)-Dihydrocubebin
|
CHEMBL486597
CHEMBL1477391 |
C011228
|
4 / 8 / 4 | No. 629 | No. 21 |
|
|
|
C00002683
|
Vanillin
|
CHEMBL13883
|
18 / 8 / 9 | No. 1003 |
|
|||
|
C00002682
|
Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid |
CHEMBL120568
|
D014641
|
5 / 3 / 3 | 5 / 0 | No. 1073 |
|
|
|
C00001122
|
Glucose
/ D-Glucose / alpha-D-Glucose |
CHEMBL300520
CHEMBL98182 CHEMBL103010 CHEMBL423707 CHEMBL195923 CHEMBL469448 CHEMBL1222152 CHEMBL1222250 CHEMBL1233058 CHEMBL1453070 CHEMBL1519430 CHEMBL1614854 CHEMBL1873035 CHEMBL2093058 CHEMBL2115552 |
26 / 15 / 15 | No. 1283 |
|
|||
|
C00036761
|
Aristolactam IIIa N-beta-glucoside
|
No. 1580 |
|
|||||
|
C00027286
|
Aristolactam I N-beta-glucoside
|
C062008
|
No. 1580 |
|
||||
|
C00012492
|
Kobusone
/ (-)-Kobusone |
CHEMBL1592474
|
1 / 0 / 1 | No. 1620 |
|
|||
|
C00036762
|
Aristolin
/ (-)-Aristolin |
No. 7447 |
|
|||||
|
C00007468
|
Allantoin
|
CHEMBL593429
CHEMBL1230080 |
D000481
|
12 / 12 / 14 | No. 8950 |
|
Human Protein / Gene in interactions
85 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000601 C00001526 C00002591 C00002599 C00002608 C00007468 C00012492 C00023770 C00032730 C00036281 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000601 C00002591 C00002599 C00002608 C00007468 C00023770 C00036281 | 1 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00001526 C00027520 C00032729 C00032730 C00032731 C00032766 C00036281 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000601 C00001526 C00002611 C00032730 C00032766 C00036281 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001526 C00002611 C00002683 C00032730 C00036281 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000601 C00001526 C00002683 C00032730 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001526 C00002683 C00032730 C00036281 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000601 C00007468 C00023770 C00036281 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000601 C00001526 C00002611 C00032730 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000601 C00007468 C00023770 C00036281 | 0 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001122 C00002683 C00023770 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00007468 C00023770 C00036281 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000601 C00001526 C00032730 | 4 / 3 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001122 C00001526 C00032730 | 1 / 2 |
| O00255 | Menin | Unclassified protein | C00001122 C00001526 C00032730 | 2 / 5 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000601 C00002611 C00002682 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000601 C00001526 C00032730 | 4 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00007468 C00023770 | 3 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00007468 C00036281 | 0 / 1 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002611 C00007468 | 4 / 2 |
| P03372 | Estrogen receptor | NR3A1 | C00002682 C00023770 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000640 C00001122 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001526 C00032730 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000601 C00002599 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000601 C00002683 | 2 / 2 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000601 C00007468 | 2 / 3 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001122 C00036281 | 1 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00023770 C00025334 | 4 / 2 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00001526 C00032730 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002611 C00032766 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00000640 C00001122 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000601 C00007468 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000601 C00002611 | 2 / 0 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00007468 C00036281 | 1 / 4 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000601 C00001122 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00001122 C00002682 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000601 C00002599 | 7 / 3 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000601 C00002611 | 1 / 1 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00002683 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00023770 | 0 / 0 |
| P07306 | Asialoglycoprotein receptor 1 | Membrane receptor | C00001122 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00001122 | 1 / 2 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00002683 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00002682 | 1 / 1 |
| P00734 | Prothrombin | S1A | C00023770 | 4 / 2 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000601 | 0 / 0 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00002683 | 1 / 1 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002683 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000601 | 0 / 0 |
| P11216 | Glycogen phosphorylase, brain form | Enzyme | C00001122 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00036281 | 3 / 3 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00002683 | 0 / 0 |
| P09382 | Galectin-1 | Other cytosolic protein | C00001122 | 0 / 0 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00002683 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00023770 | 1 / 0 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00002682 | 1 / 1 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002683 | 0 / 0 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002683 | 1 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00002683 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002611 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001122 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001122 | 3 / 1 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00002683 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00023770 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00002683 | 3 / 4 |
| Q6P4F1 | Alpha-(1,3)-fucosyltransferase 10 | Enzyme | C00001122 | 0 / 0 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00023770 | 1 / 1 |
| P17931 | Galectin-3 | Other cytosolic protein | C00001122 | 0 / 1 |
| P11226 | Mannose-binding protein C | Unclassified protein | C00001122 | 2 / 2 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00036281 | 0 / 0 |
| O14924 | Regulator of G-protein signaling 12 | Unclassified protein | C00007468 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00023770 | 0 / 0 |
| P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | C00002683 | 0 / 0 |
| Q9NNX6 | CD209 antigen | Unclassified protein | C00001122 | 2 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00023770 | 2 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00002683 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00023770 | 0 / 0 |
| P10323 | Acrosin | S1A | C00001122 | 0 / 0 |
| Q9UJ71 | C-type lectin domain family 4 member K | Unclassified protein | C00001122 | 1 / 0 |
| P22897 | Macrophage mannose receptor 1 | Unclassified protein | C00001122 | 0 / 0 |
| Q8WTT0 | C-type lectin domain family 4 member C | Unclassified protein | C00001122 | 0 / 0 |
| Q6EIG7 | C-type lectin domain family 6 member A | Unclassified protein | C00001122 | 0 / 0 |
| P35247 | Pulmonary surfactant-associated protein D | Unclassified protein | C00001122 | 0 / 0 |
| Q9H2X3 | C-type lectin domain family 4 member M | Unclassified protein | C00001122 | 0 / 0 |
| P11217 | Glycogen phosphorylase, muscle form | Enzyme | C00001122 | 1 / 1 |
26 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 59 | ACTA2, AAT6, ACTSA, MYMY5 | actin, alpha 2, smooth muscle, aorta |
C00001526
|
| 655 | BMP7, OP-1 | bone morphogenetic protein 7 |
C00001526
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001526
|
| 999 | CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO | cadherin 1, type 1, E-cadherin (epithelial) |
C00001526
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001526
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001526
|
| 1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00001526
|
| 1965 | EIF2S1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
C00001526
|
| 2034 | EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 | endothelial PAS domain protein 1 |
C00001526
|
| 26585 | GREM1, CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2 | gremlin 1, DAN family BMP antagonist |
C00001526
|
| 3309 | HSPA5, BIP, GRP78, MIF2 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
C00001526
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00001526
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00001526
|
| 55867 | SLC22A11, OAT4, hOAT4 | solute carrier family 22 (organic anion/urate transporter), member 11 |
C00001526
|
| 9356 | SLC22A6, HOAT1, OAT1, PAHT, ROAT1 | solute carrier family 22 (organic anion transporter), member 6 |
C00001526
|
| 9376 | SLC22A8, OAT3 | solute carrier family 22 (organic anion transporter), member 8 |
C00001526
|
| 4086 | SMAD1, BSP-1, BSP1, JV4-1, JV41, MADH1, MADR1 | SMAD family member 1 |
C00001526
|
| 4090 | SMAD5, DWFC, JV5-1, MADH5 | SMAD family member 5 |
C00001526
|
| 4093 | SMAD9, MADH6, MADH9, PPH2, SMAD8, SMAD8A, SMAD8B | SMAD family member 9 |
C00001526
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00001526
|
| 7494 | XBP1, TREB5, XBP-1, XBP2 | X-box binding protein 1 |
C00001526
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00002682
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00002682
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00002682
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00002682
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00002682
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (69)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #613393 | Birbeck granule deficiency |
Q9UJ71
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #614371 | Dengue virus, susceptibility to |
Q9NNX6
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232600 | Glycogen storage disease v |
P11217
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610424 | Hepatitis b virus, susceptibility to |
P11226
|
| #143100 | Huntington disease; hd |
P42858
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #614372 | Mannose-binding protein deficiency |
P11226
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
Q9NNX6 |
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (52)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
P11308 (related) |
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P11217
(related)
|
| H00105 | Mannose-binding lectin pathway component defects |
P11226
(related)
|
| H00342 | Tuberculosis |
P11226
(related)
P11473 (related) |
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00032 | Thyroid cancer |
P17931
(marker)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
17 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001284 | Atrophy |
C00001526
|
| D001449 | Balkan Nephropathy |
C00001526
|
| D018376 | Cardiovascular Abnormalities |
C00001526
|
| D007249 | Inflammation |
C00001526
|
| D007674 | Kidney Diseases |
C00001526
|
| D007680 | Kidney Neoplasms |
C00001526
|
| D007683 | Kidney Tubular Necrosis, Acute |
C00001526
|
| D009369 | Neoplasms |
C00001526
|
| D051437 | Renal Insufficiency |
C00001526
|
| D014571 | Urologic Neoplasms |
C00001526
|
| D001930 | Brain Injuries |
C00000601
|
| D002375 | Catalepsy |
C00000601
|
| D018476 | Hypokinesia |
C00000601
|
| D020244 | Infarction, Middle Cerebral Artery |
C00000601
|
| D020734 | Parkinsonian Disorders |
C00000601
|
| D004487 | Edema |
C00002591
|
| D010146 | Pain |
C00002591
|