| class name | count |
|---|---|
| rosids | 3 |
| asterids | 2 |
| Magnoliophyta | 2 |
| Liliopsida | 1 |
| eudicotyledons | 1 |
| class name | count |
|---|---|
| Fabaceae | 2 |
| Aristolochiaceae | 2 |
| Brassicaceae | 1 |
| Amaryllidaceae | 1 |
| Boraginaceae | 1 |
| Acanthaceae | 1 |
| Caryophyllaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00007468
|
Allantoin
|
CHEMBL593429
CHEMBL1230080 |
D000481
|
12 / 12 / 14 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00007468 | 1 / 0 |
| O14924 | Regulator of G-protein signaling 12 | Unclassified protein | C00007468 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00007468 | 4 / 2 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00007468 | 3 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00007468 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00007468 | 2 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00007468 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00007468 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00007468 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00007468 | 0 / 1 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00007468 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00007468 | 1 / 4 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|