PCIDB

KNApSAcK Metabolite C00007468

Metabolite

KNApSAcK Entry

id C00007468
Name Allantoin
CAS RN 97-59-6
Standard InChI InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)
Standard InChI (Main Layer) InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)

Cluster

Phytochemical cluster
KCF-S cluster No. 8950

Link

ChEMBL

By standard InChI CHEMBL593429
By standard InChI Main Layer CHEMBL593429 CHEMBL1230080

KEGG

By LinkDB C01551

CTD

By CAS RN D000481

Human Protein / Gene in interaction

12 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1230080 CHEMBL1741321 (1)
1 / 0
O14924 Regulator of G-protein signaling 12 Unclassified protein CHEMBL593429 CHEMBL1613902 (1)
0 / 0
P37840 Alpha-synuclein Unclassified protein CHEMBL593429 CHEMBL2354282 (1)
4 / 2
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL1230080 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1230080 CHEMBL1741325 (1)
0 / 1
P11473 Vitamin D3 receptor NR1I1 CHEMBL593429 CHEMBL1794311 (1)
2 / 3
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL1230080 CHEMBL1794467 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1230080 CHEMBL1741322 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1230080 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1230080 CHEMBL1741324 (1)
0 / 1
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL1230080 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL1230080 CHEMBL1613933 (1)
1 / 6

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (14)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)