Species

KNApSAcK Entry

Organism name Vaccaria segetalis
Genus Vaccaria
Family Caryophyllaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Vaccaria hispanica
Linked NCBI taxonomy ID 39387
Linked level species

Family

Family in NCBI taxonomy Caryophyllaceae
ID 3568

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (19)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006393 External link 512 Isosaponarin
CHEMBL1643081
No. 1 No. 15
C00031435 External link 512 Vaccaroside A
/ (+)-Vaccaroside A
CHEMBL554779
No. 4 No. 51
C00044369 External link 512 Vaccaroside F
No. 4 No. 51
C00049025 External link 512 Vaccaroside C
/ (-)-Vaccaroside C
No. 4 No. 51
C00049024 External link 512 Vaccaroside B
/ (+)-Vaccaroside B
CHEMBL559335
No. 4 No. 51
C00044368 External link 512 Vaccaroside E
No. 4 No. 51
C00049026 External link 512 Vaccaroside D
/ (-)-Vaccaroside D
No. 4 No. 51
C00044370 External link 512 Vaccaroside G
No. 4 No. 51
C00044371 External link 512 Vaccaroside H
No. 4 No. 51
C00040610 External link 512 Vaccegoside B
No. 4 No. 51
C00014037 External link 512 Vaccarin
/ Isovitexin 4'-O-glucoside 2''-O-arabinoside
/ 6-(2-O-alpha-L-Arabinopyranosyl-beta-D-glucopyranosyl)-2-[4-(beta-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
No. 5 No. 15
C00040611 External link 512 Vaccegoside C
No. 49 No. 51
C00028984 External link 512 Segetalin E
No. 498
C00042992 External link 512 Segetalin H
CHEMBL384334
No. 745
C00044311 External link 512 Segetoside A
/ (+)-Segetoside A
No. 1264
C00027067 External link 512 Segetalin A
/ (-)-Segetalin A
CHEMBL378333
No. 2574
C00028983 External link 512 Vaccarin A
/ Segetalin B
No. 3199
C00050232 External link 512 Segetalin G
CHEMBL387421
No. 3199
C00007468 External link 512 Allantoin
CHEMBL593429
CHEMBL1230080
D000481
12 / 12 / 14 No. 8950

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00007468 1 / 0
O14924 Regulator of G-protein signaling 12 Unclassified protein C00007468 0 / 0
P37840 Alpha-synuclein Unclassified protein C00007468 4 / 2
P16473 Thyrotropin receptor Glycohormone receptor C00007468 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00007468 0 / 1
P11473 Vitamin D3 receptor NR1I1 C00007468 2 / 3
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00007468 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00007468 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00007468 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00007468 0 / 1
Q13951 Core-binding factor subunit beta Unclassified protein C00007468 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00007468 1 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (14)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)