phytochemical cluster No. 23 (72 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• KCF-S cluster (11)
• Metabolite list (72)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Magnoliophyta	82
rosids	16
asterids	11
Spermatophyta	5
Liliopsida	5
eudicotyledons	1

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Cumulative family count (Top 20)

class name	count
Magnoliaceae	33
Piperaceae	18
Lauraceae	13
Myristicaceae	11
Rubiaceae	5
Rutaceae	5
Schisandraceae	4
Taxaceae	3
Aristolochiaceae	3
Araceae	3
Cupressaceae	2
Moraceae	2
Malvaceae	2
Poaceae	1
Cucurbitaceae	1
Celastraceae	1
Lamiaceae	1
Plantaginaceae	1
Asteraceae	1
Eucommiaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Neolignans	14

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metabolites link (14)

br08003 Category	KEGG ID	KNApSAcK ID
Neolignans	C10690	C00000588
Neolignans	C10651	C00000591
Neolignans	C10554	C00000671
Neolignans	C10638	C00000719
Neolignans	C10550	C00002592
Neolignans	C10562	C00002602
Neolignans	C10563	C00002603
Neolignans	C10574	C00002604
Neolignans	C10630	C00002609
Neolignans	C10640	C00002610
Neolignans	C10650	C00002611
Neolignans	C10878	C00002622
Neolignans	C10888	C00002630
Neolignans	C10446	C00002734

KCF-S cluster (11)

KCF-S ID	# of metabolite
No. 215	29
No. 761	11
No. 1500	7
No. 1419	7
No. 2047	5
No. 2844	4
No. 2788	4
No. 3583	2
No. 6866	1
No. 6963	1
No. 7135	1

Metabolite list (72)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	figure
C00047413	Diferulic acid					No. 215
C00000589	Fragnasol C					No. 215
C00047049	(-)-Megaphone					No. 215
C00047048	Dehydrodieugenol	CHEMBL182629				No. 215
C00000672	Fragransol D					No. 215
C00000685	Licarin B	CHEMBL259386 CHEMBL578403	C119225			No. 215
C00000696	(-)-Simulanol	CHEMBL253334 CHEMBL1761711				No. 215
C00047038	Fargesone A					No. 215
C00044284	Eudesmagnolol / (-)-Eudesmagnolol / [2R-(2alpha,4aalpha,8beta,8abeta)]-Decahydro-8-[(2'-hydroxy-5,5'-di-2-propenyl[1,1'-biphenyl]-2-yl)oxy]-alpha,a,4alpha,8-tetramethyl-2-naphthalenemethanol					No. 215
C00041632	(-)-Piperenone	CHEMBL33562				No. 215
C00040931	Futoquinol	CHEMBL498296				No. 215
C00024175	Perseal C / (-)-Perseal C					No. 215
C00039281	Rhaphidecursinol B	CHEMBL462321 CHEMBL464122				No. 215
C00038044	Polysyphorin	CHEMBL460235 CHEMBL1928007 CHEMBL2086453	C071829			No. 215
C00036289	Surinamensin	CHEMBL464726 CHEMBL464934 CHEMBL2313009	C420461			No. 215
C00002611	Licarin D					No. 215
C00035505	Myristicanol B					No. 215
C00033656	Nirandin A	CHEMBL30352 CHEMBL570291				No. 215
C00032977	Burchellin		C053585			No. 215
C00032698	Hancinone	CHEMBL606463				No. 215
C00031456	threo-Honokitriol / (+)-threo-Honokitriol					No. 215
C00030883	erythro-Honokitriol / (-)-erythro-Honokitriol					No. 215
C00020651	Fragnasol A					No. 215
C00024156	Ficusal / (+)-Ficusal					No. 215
C00024157	Perseal F / (-)-Perseal F	CHEMBL459216				No. 215
C00030874	4-Methoxyhonokiol / 4-O-Methyl honokiol					No. 215
C00030572	Magnaldehyde B	CHEMBL250885				No. 215
C00024174	Chushizisin E / (-)-Chushizisin E	CHEMBL571673				No. 215
C00039958	Isodihydrofutoquinol A	CHEMBL290066				No. 215
C00029537	Randaiol	CHEMBL555924				No. 761
C00000591	Acuminatin / (+)-Acuminatin	CHEMBL571195	C077860			No. 761
C00040486	Fargesone C					No. 761
C00030707	Randainol					No. 761
C00030708	Magnolol	CHEMBL180920	C005498	21 / 17 / 15	1 / 7	No. 761
C00030709	Hinokiol / (+)-Hinokiol	CHEMBL16901		26 / 24 / 20		No. 761
C00040143	Isodihydrofutoquinol B / (+)-Isodihydrofutoquinol B	CHEMBL290066				No. 761
C00039712	Virolongin A					No. 761
C00039166	Rhaphidecursinol A / (+)-Rhaphidecursinol A					No. 761
C00002622	Dihydrodehydrodiconiferyl alcohol	CHEMBL261907 CHEMBL253590				No. 761
C00002609	Balanophonin / (-)-Balanophonin	CHEMBL253335 CHEMBL468666 CHEMBL590760 CHEMBL1956166				No. 761
C00041404	Piperkadsin A / (-)-Piperkadsin A	CHEMBL526286				No. 1419
C00032901	Denudatin A	CHEMBL606463				No. 1419
C00000719	Licarin A / (-)-Licarin A	CHEMBL259731 CHEMBL463526 CHEMBL1732407		9 / 7 / 3		No. 1419
C00041535	Kadsurin B	CHEMBL41463				No. 1419
C00000671	Odoratisol A					No. 1419
C00033250	Kadsurenone / Kadsurenone A	CHEMBL30122 CHEMBL296958 CHEMBL571196 CHEMBL2114380	C044540			No. 1419
C00031846	Magnolignan C / (-)-Magnolignan C	CHEMBL399697				No. 1419
C00037993	Myristicanol A					No. 1500
C00024159	Curlignan / (+)-Curlignan					No. 1500
C00002630	(+)-Dihydrodehydrodiconiferyl alcohol	CHEMBL261907 CHEMBL253590				No. 1500
C00046323	Eudesobovatol B / [2R-(2alpha,4aalpha,8beta,8abeta)]-Decahydro-8-[2-hydroxy-4-(2-propenyl)-6-[4-(2-propenyl)phenoxy]phenoxy]-alpha,alpha,4a,8-tetramethyl-2-naphthalenemethanol					No. 1500
C00024158	Melanoxin	CHEMBL1801604				No. 1500
C00046356	Eudesobovatol A					No. 1500
C00046357	Fargesone B					No. 1500
C00002604	Dehydrodiconiferyl alcohol	CHEMBL406378 CHEMBL590520 CHEMBL1761712	C080686			No. 2047
C00033059	Futoenone / (-)-Futoenone	CHEMBL295191		3 / 3 / 3		No. 2047
C00033060	(+)-Denudatin B	CHEMBL30122 CHEMBL296958 CHEMBL571196 CHEMBL2114380				No. 2047
C00030245	Magnaldehyde E	CHEMBL251060				No. 2047
C00041766	Eudeshonokiol / Eudeshonokiol A / (-)-Eudeshonokiol					No. 2047
C00000699	(-)-5-Methoxybalanophonin	CHEMBL413991				No. 2788
C00041611	Kadsurin A / (+)-Kadsurin A	CHEMBL37432				No. 2788
C00002610	Glycosmisic acid	CHEMBL2346742				No. 2788
C00041633	Liliflone					No. 2788
C00012707	Fragransol-B					No. 2844
C00002602	Obovatifol					No. 2844
C00012820	Fragransol A					No. 2844
C00012763	5-methoxy-trans-dihydrodehydrodiconiferyl alcohol					No. 2844
C00002603	Kachirachirol B / (-)-Kachirachirol B					No. 3583
C00031784	Magnolignan B					No. 3583
C00002592	Dehydrodiisoeugenol	CHEMBL259731 CHEMBL463526 CHEMBL1732407		9 / 7 / 3		No. 6866
C00000588	Fragransol C					No. 6963
C00002734	4-O-Methylcedrusin	CHEMBL457819				No. 7135

Human Protein / Gene in interactions

38 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000591 C00002609 C00002611 C00047038	0 / 0
O75496	Geminin	Unclassified protein	C00000591 C00002609 C00002611 C00047038	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000591 C00002609 C00002611 C00047038	2 / 0
P39748	Flap endonuclease 1	Enzyme	C00002609 C00002611 C00047038	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002609 C00002611 C00047038	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00002609 C00002611 C00047038	4 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000591 C00002611 C00047038	1 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00000591 C00002609	4 / 3
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00000591 C00002609	0 / 0
Q9GZV3	High affinity choline transporter 1	Choline Na-symporter	C00000591 C00002609	1 / 0
P34972	Cannabinoid receptor 2	Cannabinoid receptor	C00000591 C00002609	0 / 0
O00255	Menin	Unclassified protein	C00000591 C00002609	2 / 5
Q9UNA4	DNA polymerase iota	Enzyme	C00002611 C00047038	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000591 C00002609	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000591 C00002609	1 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000591 C00002609	1 / 2
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002611 C00047038	0 / 0
Q9Y2T6	G-protein coupled receptor 55	Lysophosphatidylinositol receptor	C00000591 C00002609	0 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00000591 C00002609	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00000591 C00002609	1 / 1
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002609	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002609	2 / 2
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002609	5 / 3
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00002609	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000591	2 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00000591	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00000591	1 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00000591	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002609	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002609	0 / 0
P08254	Stromelysin-1	M10A	C00041535	1 / 0
P14780	Matrix metalloproteinase-9	M10A	C00041535	2 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000591	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000591	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00002609	0 / 0
P06746	DNA polymerase beta	Enzyme	C00002609	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002609	0 / 0
P03956	Interstitial collagenase	M10A	C00041535	0 / 1

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00000591

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions