KCF-S cluster No. 1073 (9 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	47
asterids	36
Liliopsida	14
Magnoliophyta	10
eudicotyledons	7
Spermatophyta	5
Euphyllophyta	1
Embryophyta	1

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Cumulative family count (Top 20)

class name	count
Rutaceae	9
Asteraceae	8
Malvaceae	6
Plantaginaceae	6
Fabaceae	5
Lamiaceae	4
Bignoniaceae	4
Piperaceae	4
Rosaceae	4
Apiaceae	3
Rhamnaceae	3
Pinaceae	3
Aristolochiaceae	3
Celastraceae	3
Hypoxidaceae	2
Lauraceae	2
Euphorbiaceae	2
Rubiaceae	2
Posidoniaceae	2
Asparagaceae	2

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002674	Syringic acid / 4-Hydroxy-3,5-dimethoxybenzoic acid	CHEMBL1414	C001945	12 / 3 / 5
C00002682	Vanillic acid / 3-Methoxy-4-hydroxybenzoic acid	CHEMBL120568	D014641	5 / 3 / 3	5 / 0
C00029476	Eudesmic acid / Trimethylgallic acid / 3,4,5-Trimethoxybenzoic acid	CHEMBL377172	C005854	3 / 2 / 2
C00029479	Veratric acid / 3,4-dimethoxybenzoic acid	CHEMBL118903	C009333	10 / 6 / 6
C00029502	3-Hydroxy-4-methoxybenzoic acid	CHEMBL88700	C045317	2 / 1 / 4
C00034769	4-Hydroxy-2-methoxybenzoic acid
C00035926	3,4-dimethoxybenzoic acid	CHEMBL118903	C009333	10 / 6 / 6
C00035948	4-Ethoxy-3-methoxybenzoic acid	CHEMBL1363623		7 / 12 / 8
C00040794	2,6-Dimethoxy-benzoic acid	CHEMBL488609	C472445	6 / 2 / 4

Human Protein / Gene in interactions

28 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002674 C00029479 C00035926 C00040794	0 / 0
P51580	Thiopurine S-methyltransferase	Enzyme	C00002682 C00029479 C00029502 C00035926	1 / 1
Q16790	Carbonic anhydrase 9	Lyase	C00002674 C00029479 C00035926 C00040794	0 / 1
P00915	Carbonic anhydrase 1	Lyase	C00002674 C00029479 C00035926 C00040794	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002674 C00029479 C00035926 C00040794	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002674 C00029479 C00035926 C00040794	1 / 2
O43570	Carbonic anhydrase 12	Lyase	C00002674 C00029479 C00035926 C00040794	1 / 2
P22748	Carbonic anhydrase 4	Lyase	C00002674 C00029479 C00035926	1 / 1
P23280	Carbonic anhydrase 6	Lyase	C00002674 C00029479 C00035926	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00029479 C00035926	2 / 0
P15121	Aldose reductase	Enzyme	C00002674 C00002682	0 / 0
P42858	Huntingtin	Unclassified protein	C00002682	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00035948	0 / 1
O75496	Geminin	Unclassified protein	C00029476	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00035948	3 / 2
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002674	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00035948	7 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00029476	0 / 0
P51843	Nuclear receptor subfamily 0 group B member 1	Nuclear hormone receptor subfamily 0 group B member 1	C00029476	2 / 2
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00035948	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002674	0 / 0
P03372	Estrogen receptor	NR3A1	C00002682	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00029502	0 / 3
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00035948	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00035948	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002682	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00002674	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00035948	1 / 0

5 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002682
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002682
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002682
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002682
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002682

Related Diseases

Diseases related to proteins in ChEMBL interactions