KNApSAcK Metabolite C00002685
Metabolite
KNApSAcK Entry
| id | C00002685 |
|---|---|
| Name | Acetophenone |
| CAS RN | 98-86-2 |
| Standard InChI | InChI=1S/C8H8O/c1-7(9)8-5-3-2-4-6-8/h2-6H,1H3 |
| Standard InChI (Main Layer) | InChI=1S/C8H8O/c1-7(9)8-5-3-2-4-6-8/h2-6H,1H3 |
Cluster
| Phytochemical cluster | No. 9 |
|---|---|
| KCF-S cluster | No. 2578 |
Link
ChEMBL
| By standard InChI | CHEMBL274467 |
|---|---|
| By standard InChI Main Layer | CHEMBL274467 |
KEGG
| By LinkDB | C07113 |
|---|
CTD
| By CAS RN | C038699 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 5 |
| eudicotyledons | 1 |
Family
| family name | count |
|---|---|
| Cistaceae | 2 |
| Salicaceae | 1 |
| Cyprinidae | 1 |
| Euphorbiaceae | 1 |
| Proteaceae | 1 |
| Urticaceae | 1 |
| Apidae | 1 |
List (8)
* NCBI
Human Protein / Gene in interaction
2 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q13464 | Rho-associated protein kinase 1 | Rock | CHEMBL274467 |
CHEMBL1647663
(1)
|
0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | CHEMBL274467 |
CHEMBL1042446
(1)
|
0 / 0 |
CTD interaction (2)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C038699 | 217 |
ALDH2
ALDH-E2 ALDHI ALDM |
aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) | acetophenone inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein] |
affects binding
/ decreases reaction |
protein |
10609638
|
| C038699 | 250 |
ALPP
ALP PALP PLAP PLAP-1 |
alkaline phosphatase, placental (EC:3.1.3.1) | ALPP protein results in increased chemical synthesis of acetophenone |
increases chemical synthesis
|
protein |
1495895
|