| Organism name | Cistus ladaniferus | 
|---|---|
| Genus | Cistus | 
| Family | Cistaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Cistus | 
|---|---|
| Linked NCBI taxonomy ID | 69451 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Cistaceae | 
|---|---|
| ID | 69450 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00005406   | Quercetin 3-xylosyl-(1->6)-glucoside | CHEMBL451224 | No. 1 | No. 15 |   | |||
| C00005541   | Isorhamnetin 3-xylosyl-(1->6)-glucoside | No. 1 | No. 15 |   | ||||
| C00005425   | Quercetin 3-galactoside-7-rhamnoside | CHEMBL592361 CHEMBL1774171 | No. 1 | No. 15 |   | |||
| C00005737   | Myricetin 3-rutinoside / Myricetin-3-O-rutinoside | No. 1 | No. 15 |   | ||||
| C00005169   | Nicotiflorin / Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside | CHEMBL431610 CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691 | 22 / 10 / 12 | No. 1 | No. 15 |   | ||
| C00005409   | Quercetin 3-O-sophoroside | CHEMBL452919 | C055545 | No. 1 | No. 15 |   | ||
| C00005400   | Quercetin 3-rhamnosyl-(1->2)-galactoside | CHEMBL499824 | C064703 | No. 1 | No. 15 |   | ||
| C00005729   | Myricetin 3-glucoside / Myricetin 3-O-beta-D-glucoside / Myricetin 3-O-beta-D-glucopyranoside | CHEMBL462244 CHEMBL1221722 | No. 2 | No. 15 |   | |||
| C00001260   | Nonacosane | CHEMBL428955 | C047577 | No. 115 |   | |||
| C00001250   | Hentriacontane | CHEMBL257490 | C049203 | No. 115 |   | |||
| C00000170   | trans-Cinnamate / trans-Cinnamic acid | CHEMBL27246 | 5 / 2 / 2 | No. 904 | No. 6 |   | ||
| C00023430   | Ambreinolide | No. 1139 |   | |||||
| C00002685   | Acetophenone | CHEMBL274467 | C038699 | 2 / 0 / 0 | 2 / 0 | No. 2578 | No. 9 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000170 C00005169 | 1 / 1 | 
| P15121 | Aldose reductase | Enzyme | C00000170 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00005169 | 1 / 1 | 
| P06746 | DNA polymerase beta | Enzyme | C00005169 | 0 / 0 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00005169 | 1 / 1 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005169 | 0 / 0 | 
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000170 | 0 / 0 | 
| P07237 | Protein disulfide-isomerase | Enzyme | C00005169 | 0 / 0 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005169 | 1 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00005169 | 2 / 3 | 
| Q13464 | Rho-associated protein kinase 1 | Rock | C00002685 | 0 / 0 | 
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000170 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00005169 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00005169 | 0 / 0 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00005169 | 0 / 0 | 
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00002685 | 0 / 0 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00005169 | 1 / 1 | 
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005169 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00000170 | 1 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00005169 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00005169 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00005169 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00005169 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00005169 | 0 / 0 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00005169 | 0 / 1 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00005169 | 1 / 4 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005169 | 0 / 0 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00005169 | 2 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 217 | ALDH2, ALDH-E2, ALDHI, ALDM | aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) | C00002685 | 
| 250 | ALPP, ALP, PALP, PLAP, PLAP-1 | alkaline phosphatase, placental (EC:3.1.3.1) | C00002685 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #114500 | Colorectal cancer; crc | Q14191 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #160900 | Myotonic dystrophy 1; dm1 | Q9NR56 | 
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | Q01196 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| #277700 | Werner syndrome; wrn | Q14191 | 
| #278300 | Xanthinuria, type i | P47989 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00026 | Endometrial Cancer | P03372
                            (marker) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q01196
                            (related) Q01196 (marker) | 
| H00003 | Acute myeloid leukemia (AML) | Q01196
                            (related) Q01196 (marker) Q13951 (marker) | 
| H00004 | Chronic myeloid leukemia (CML) | Q01196
                            (related) | 
| H00978 | Thrombocytopenia (THC) | Q01196
                            (related) | 
| H00296 | Defects in RecQ helicases | Q14191
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) |