PCIDB

KNApSAcK Metabolite C00001237

Metabolite

KNApSAcK Entry

id C00001237
Name Ricinoleic acid
CAS RN 141-22-0
Standard InChI InChI=1S/C18H34O3/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21/h9,12,17,19H,2-8,10-11,13-16H2,1H3,(H,20,21)/b12-9-/t17-/m1/s1
Standard InChI (Main Layer) InChI=1S/C18H34O3/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21/h9,12,17,19H,2-8,10-11,13-16H2,1H3,(H,20,21)

Cluster

Phytochemical cluster No. 68
KCF-S cluster No. 184

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL1877670

KEGG

By LinkDB C08365

CTD

By CAS RN C030521

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Brassicaceae 1
Euphorbiaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Lesquerella densipila 98013 Brassicaceae rosids Viridiplantae
Ricinus opp. 3977 Euphorbiaceae rosids Viridiplantae

Human Protein / Gene in interaction

2 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P11473 Vitamin D3 receptor NR1I1 CHEMBL1877670 CHEMBL1794311 (1)
2 / 3
O75496 Geminin Unclassified protein CHEMBL1877670 CHEMBL2114843 (1)
0 / 0

CTD interaction (5)

compound gene gene name gene description interaction interaction type form reference
pmid
C030521 1268 CNR1
CANN6
CB-R
CB1
CB1A
CB1K5
CB1R
CNR
cannabinoid receptor 1 (brain) ricinoleic acid analog binds to CNR1 protein affects binding
protein 16406364
C030521 1269 CNR2
CB-2
CB2
CX5
cannabinoid receptor 2 (macrophage) ricinoleic acid analog binds to and affects the activity of CNR2 protein affects activity
/ affects binding
protein 16406364
C030521 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] decreases reaction
/ increases expression
protein 7544037
C030521 7442 TRPV1
VR1
transient receptor potential cation channel, subfamily V, member 1 ricinoleic acid analog binds to and affects the activity of TRPV1 protein affects activity
/ affects binding
protein 16406364
C030521 7412 VCAM1
CD106
INCAM-100
vascular cell adhesion molecule 1 ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] decreases reaction
/ increases expression
protein 7544037

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (3)

KEGG disease name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)