phytochemical cluster No. 68 (74 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• KCF-S cluster (6)
• Metabolite list (74)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	151
asterids	73
Liliopsida	26
eudicotyledons	22
Embryophyta	20
Magnoliophyta	15
Viridiplantae	4
Euphyllophyta	3
Spermatophyta	2

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Cumulative family count (Top 20)

class name	count
Brassicaceae	61
Calophyllaceae	23
Frullaniaceae	20
Boraginaceae	20
Fabaceae	16
Asteraceae	15
Rosaceae	9
Caryophyllaceae	9
Ganodermataceae	7
Solanaceae	7
Corallinaceae	7
Poaceae	7
Saxifragaceae	7
Malvaceae	6
Urticaceae	6
Lamiaceae	6
Euphorbiaceae	6
Lauraceae	6
Arecaceae	6
Crassulaceae	5

KEGG BRITE br08003

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Categories (2)

br08003 Category	# of metabolite
Saturated fatty acids	10
Unsaturated fatty acids	9

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metabolites link (22)

br08003 Category	KEGG ID	KNApSAcK ID
Saturated fatty acids	C00246	C00001180
Saturated fatty acids	C06425	C00001209
Saturated fatty acids	C08281	C00001211
Saturated fatty acids	C01571	C00001213
Unsaturated fatty acids	C08316	C00001217
Saturated fatty acids	C01585	C00001218
Saturated fatty acids	C02679	C00001221
Unsaturated fatty acids	C01595	C00001224
Unsaturated fatty acids	C06426	C00001226
Saturated fatty acids	C06424	C00001228
Unsaturated fatty acids	C08322	C00001229
Saturated fatty acids	C06423	C00001231
Unsaturated fatty acids	C00712	C00001232
Saturated fatty acids	C00249	C00001233
Unsaturated fatty acids	C08362	C00001234
Unsaturated fatty acids	C08364	C00001236
Unsaturated fatty acids	C08365	C00001237
Saturated fatty acids	C01530	C00001238
Unsaturated fatty acids	C08367	C00001240
Unsaturated fatty acids	C08362	C00029354
Saturated fatty acids	C00249	C00030479
Saturated fatty acids	C01530	C00032087

KCF-S cluster (6)

KCF-S ID	# of metabolite
No. 184	30
No. 367	14
No. 300	10
No. 1100	9
No. 1141	8
No. 3692	3

Metabolite list (74)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	figure
C00034998	24-Hydroxytetracosanoic acid					No. 184
C00047287	Caproic acid / Hexanoic acid / 1-Hexanoic acid / n-Hexanoic acid	CHEMBL14184	C037652	5 / 0 / 0		No. 184
C00044476	Tridecanoic acid	CHEMBL107874				No. 184
C00044475	Lauric acid / Docosanoic acid / n-Dodecanoic acid	CHEMBL108766	C030358	19 / 25 / 14	11 / 0	No. 184
C00044036	Undecanoic acid	CHEMBL108030	C016173		1 / 0	No. 184
C00035628	Capric acid / Decanoic acid / n-Decanoic acid	CHEMBL107498	C031071	8 / 11 / 6	4 / 0	No. 184
C00035004	Lignoceric acid	CHEMBL1173620	C010210		1 / 0	No. 184
C00034997	23-Hydroxytricosanoic acid					No. 184
C00032087	Helenynolic acid					No. 184
C00030479	alpha-Licanic acid					No. 184
C00000442	Octadecanoic acid	CHEMBL46403	C031183	15 / 17 / 19	6 / 1	No. 184
C00029354	Colneleic acid		C002946			No. 184
C00007440	Punicic acid					No. 184
C00007439	alpha-Eleostearic acid					No. 184
C00007430	13-HPOD / 13-Hydroperoxyoctadecadienoic acid	CHEMBL1229641	C038649	2 / 3 / 7	1 / 0	No. 184
C00007426	9-HPOD / 9-Hydroperoxyoctadecadienoic acid	CHEMBL1594141		2 / 2 / 0		No. 184
C00001209	Ricinoleic acid	CHEMBL1877670	C030521	2 / 2 / 3	5 / 0	No. 184
C00007424	13-HOD / 13-Hydroxyoctadecadienoic acid / 13-Hydroxy-9Z,11E-octadecadienoic acid	CHEMBL451721 CHEMBL2069934		3 / 9 / 6		No. 184
C00007423	Avenoleic acid / 15R-Hydroxylinoleic acid					No. 184
C00001278	Linoleic acid / (Z,Z)-9,12-Octadecadienoic acid	CHEMBL267476		29 / 31 / 28		No. 184
C00001217	8S-Hydroxyhexadecanoic acid					No. 184
C00001240	(12S,13S)-EOD / (12S,13S)-Epoxylinolenic acid					No. 184
C00001238	gamma-Linolenic acid / 6(Z),9(Z),12(Z)-Octadecatrienoic acid	CHEMBL464982	D017965	17 / 8 / 5	42 / 0	No. 184
C00001237	5Z,8Z,10E,12E,14Z-Eicosapentaenoic acid					No. 184
C00001235	13S-Hydroperoxy-9Z,11E,15Z-octadecatrienoic acid					No. 184
C00001234	(13S)-HPLA / 13(S)-Hydroperoxylinolenic acid / (13S)-Hydroperoxy-cis-9,15-trans-11-octadecatrienoic acid					No. 184
C00001233	9-Hydroxy-(10E,12Z,15Z)-octadecatrienoic acid		C062142			No. 184
C00001232	15-HETE / 15-Hydroxyarachidonic acid	CHEMBL594621		1 / 0 / 0		No. 184
C00001230	12-HETE / 12-Hydroxyarachidonic acid	CHEMBL1435825 CHEMBL1526258		3 / 1 / 4		No. 184
C00001229	Crepenynic acid					No. 184
C00000363	Arachidic acid / Eicosanoic acid	CHEMBL1173381	C094477			No. 300
C00048303	Valeric acid	CHEMBL268736	C038780	1 / 7 / 3		No. 300
C00001226	6-Octadecynoic acid	CHEMBL454321				No. 300
C00000433	Stearic acid	CHEMBL46403	C031183	15 / 17 / 19	6 / 1	No. 300
C00000423	16-Hydroxyhexadecanoic acid		C063407			No. 300
C00000448	Oleic acid / (Z)-9-Octadecenoic acid	CHEMBL8659 CHEMBL460657	D019301	30 / 19 / 20	26 / 9	No. 300
C00000427	Pentadecanoic acid / n-Pentadecanoic acid	CHEMBL460025		1 / 2 / 2		No. 300
C00000364	20-Hydroxyeicosanoic acid					No. 300
C00000424	16-Hydroxy-hexadecanoic acid					No. 300
C00000389	Nervonic acid		C013147			No. 300
C00001216	Gondoic acid					No. 367
C00047136	Omega-Hydroxydodecanoic acid	CHEMBL55068	C031263		1 / 0	No. 367
C00047245	Caprylic acid / Octanoic acid / n-Octanoic acid	CHEMBL324846	C031492	10 / 14 / 13	2 / 1	No. 367
C00000393	Palmitic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 367
C00047265	Butyric acid	CHEMBL14227	D020148	12 / 3 / 2	40 / 5	No. 367
C00000394	Hexadecanoic acid / n-Hexadecanoic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 367
C00036669	Pelargonic acid / n-Nonanoic acid	CHEMBL108436	C008776	4 / 4 / 2	3 / 1	No. 367
C00001236	Colnelenic acid		C118818			No. 367
C00000449	Vaccenic acid					No. 367
C00001222	Palmitoleic acid / cis-Palmitoleic acid / (Z)-Palmitoleic acid	CHEMBL453509		2 / 5 / 3		No. 367
C00000445	18-Hydroxyoctadecanoic acid					No. 367
C00001224	Myristoleic acid	CHEMBL456732	C054211	1 / 0 / 0		No. 367
C00000403	Margaric acid / Heptadecanoic acid	CHEMBL1172910	C013102			No. 367
C00007432	Lamenallenic acid					No. 367
C00001211	Lesquerolic acid		C105775			No. 1100
C00035114	Myristic acid / Tetradecanoic acid / n-Tetradecanoic acid	CHEMBL111077	D019814	17 / 9 / 10	3 / 0	No. 1100
C00001223	cis-10-Pentadecenoic acid	CHEMBL1173463				No. 1100
C00035005	25-Hydroxypentacosanoic acid					No. 1100
C00035006	26-Hydroxyhexacosanoic acid					No. 1100
C00035007	Hexacosanoic acid	CHEMBL464787	C017364			No. 1100
C00035008	2-Hydroxytetracosanoic acid		C004226			No. 1100
C00035010	Behenic acid	CHEMBL1173474	C007547			No. 1100
C00035013	22-Hydroxydocosanoic acid					No. 1100
C00030829	14,15-Dehydrocrepenynic acid					No. 1141
C00001228	6-Nonadecynoic acid	CHEMBL454322				No. 1141
C00001231	5-HETE / 5-Hydroxyarachidonic acid	CHEMBL17695 CHEMBL164813		3 / 4 / 3		No. 1141
C00001221	Palmitoleic acid	CHEMBL453509		2 / 5 / 3		No. 1141
C00001213	Erucic acid / cis-13-Docosenoic acid	CHEMBL1173380		4 / 3 / 4		No. 1141
C00007422	18-Hydroxyoctadeca-9Z,12Z-dienoic acid					No. 1141
C00001219	10,16-Dihydroxypalmitic acid / 10,16-Dihydroxy-hexadecanoate					No. 1141
C00007421	9,12-Octadecadienoic acid	CHEMBL267476	D019787	29 / 31 / 28	42 / 11	No. 1141
C00001218	(11S)-Jalapinolic acid					No. 3692
C00001208	18-Hydroxy-9-octadecenoic acid					No. 3692
C00001180	Petroselinic acid					No. 3692

Human Protein / Gene in interactions

94 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00001213 C00001224 C00001228 C00001231 C00001232 C00001233 C00001237 C00030479 C00030829 C00036669	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001224 C00001228 C00001232 C00001233 C00001238 C00007423 C00030479 C00032087 C00036669	2 / 2
Q9UBT6	DNA polymerase kappa	Enzyme	C00001217 C00001218 C00001221 C00001224 C00001226 C00001232 C00001238 C00032087 C00036669	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000403 C00001213 C00001221 C00001224 C00001232 C00001234 C00029354 C00036669	5 / 3
P11473	Vitamin D3 receptor	NR1I1	C00000403 C00001217 C00001226 C00001228 C00001237 C00001238 C00032087	2 / 3
Q9UGP5	DNA polymerase lambda	Enzyme	C00001218 C00001221 C00001224 C00001232 C00001238 C00032087 C00036669	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00001213 C00001221 C00001224 C00001231 C00001238 C00032087 C00036669	3 / 2
P13726	Tissue factor	Membrane receptor	C00001224 C00001226 C00001229 C00001232 C00001234 C00029354 C00036669	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00001221 C00001224 C00001228 C00001232 C00001233 C00030479 C00036669	0 / 0
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00001224 C00001232 C00001233 C00001238 C00030479 C00032087 C00036669	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001224 C00001228 C00001232 C00001233 C00030479 C00036669	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00001180 C00001213 C00001218 C00001221 C00001228 C00001231	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001217 C00001224 C00001228 C00001238 C00032087 C00036669	1 / 1
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001217 C00001224 C00001226 C00001228 C00001232 C00036669	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00001213 C00001231 C00001233 C00001238 C00030479 C00032087	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001224 C00001226 C00001232 C00001233 C00030479 C00036669	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00001180 C00001213 C00001218 C00001221 C00001228 C00001231	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001224 C00001232 C00001238 C00032087 C00036669	3 / 3
P10275	Androgen receptor	NR3C4	C00001221 C00001224 C00001233 C00030479 C00036669	3 / 4
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00001224 C00001232 C00001233 C00030479 C00036669	0 / 0
P03372	Estrogen receptor	NR3A1	C00001221 C00001224 C00001233 C00030479 C00036669	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00001221 C00001226 C00001228 C00001232	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00001224 C00001238 C00032087 C00036669	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000394 C00001232 C00001238 C00032087	1 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00001221 C00001224 C00001231 C00036669	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00001221 C00001238 C00030829 C00032087	3 / 1
P35610	Sterol O-acyltransferase 1	Enzyme	C00001224 C00001232 C00036669	0 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00001232 C00001233 C00030479	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00001221 C00001224 C00036669	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00001232 C00001233 C00030479	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00001224 C00001231 C00036669	11 / 10
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00001213 C00001221 C00001232	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000393 C00000427 C00001232	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00000393 C00000403 C00001226	2 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001221 C00001226 C00001228	0 / 0
O60603	Toll-like receptor 2	Membrane receptor	C00001228 C00001233 C00030479	1 / 1
O00255	Menin	Unclassified protein	C00000394 C00001238 C00032087	2 / 5
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00001232 C00001238 C00032087	0 / 0
P08183	Multidrug resistance protein 1	drug	C00001233 C00030479	1 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001228 C00030829	1 / 1
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00001213 C00001221	3 / 0
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00001233 C00030479	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000424 C00001226	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000423 C00001232	4 / 3
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001208 C00001221	7 / 3
O14842	Free fatty acid receptor 1	Free fatty acid receptor	C00001224 C00036669	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001224 C00036669	0 / 1
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00001224 C00036669	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00001238 C00032087	0 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00001224 C00036669	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00001224 C00036669	2 / 2
P08047	Transcription factor Sp1	Unclassified protein	C00001233 C00030479	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00001224 C00036669	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00001224 C00036669	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001226 C00030829	0 / 0
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00001231	0 / 0
P49327	Fatty acid synthase	Transferase	C00001226	0 / 0
O15379	Histone deacetylase 3	Hydrolase	C00001180	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00001232	1 / 2
Q7Z4W1	L-xylulose reductase	Enzyme	C00001180	0 / 1
Q9BY41	Histone deacetylase 8	Hydrolase	C00001180	2 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001228	0 / 0
P07148	Fatty acid-binding protein, liver	Unclassified protein	C00001232	0 / 0
Q92769	Histone deacetylase 2	Hydrolase	C00001180	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00001232	1 / 4
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001232	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00001231	0 / 0
Q13547	Histone deacetylase 1	Hydrolase	C00001180	0 / 0
P56524	Histone deacetylase 4	Hydrolase	C00001180	1 / 1
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001228	2 / 2
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001226	0 / 0
Q8WUI4	Histone deacetylase 7	Hydrolase	C00001180	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001226	1 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00001221	0 / 0
Q9UQL6	Histone deacetylase 5	Hydrolase	C00001180	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001226	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001232	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00001232	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001228	0 / 0
Q05193	Dynamin-1	Structural	C00001228	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00001232	2 / 2
Q9UBN7	Histone deacetylase 6	Hydrolase	C00001180	0 / 0
Q9UKV0	Histone deacetylase 9	Hydrolase	C00001180	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000423	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00001232	0 / 0
O14880	Microsomal glutathione S-transferase 3	Enzyme	C00000423	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001226	1 / 0
P10145	Interleukin-8	Secreted protein	C00001221	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000424	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000424	1 / 4
Q9NSA0	Solute carrier family 22 member 11	Transporter	C00001231	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001226	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001226	2 / 1
P15121	Aldose reductase	Enzyme	C00001218	0 / 0

159 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001221 C00001226 C00001228 C00001231 C00001232 C00001233 C00001238 C00030479 C00030829 C00032087 C00036669
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001213 C00001221 C00001228 C00001233 C00001238 C00030479 C00032087 C00036669
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001180 C00001221 C00001232 C00001233 C00001238 C00030479 C00032087
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00001223 C00001232 C00001233 C00001238 C00030479 C00032087 C00036669
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001180 C00001226 C00001232 C00001233 C00030479 C00036669
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00001213 C00001219 C00001221 C00001231 C00007421 C00030829
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00001232 C00001233 C00001238 C00030479 C00032087 C00036669
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00001180 C00001226 C00001232 C00036669
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00001233 C00001238 C00030479 C00032087
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001226 C00001233 C00030479
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001180 C00001226 C00036669
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001221 C00001233 C00030479
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00001232 C00001233 C00030479
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001232 C00001233 C00030479
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001180 C00001233 C00030479
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00001232 C00001233 C00030479
581	BAX, BCL2L4	BCL2-associated X protein	C00001180 C00001233 C00030479
847	CAT	catalase (EC:1.11.1.6)	C00000394 C00001232 C00036669
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00001233 C00030479
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00001180 C00036669
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001221 C00036669
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00001233 C00030479
4502	MT2A, MT2	metallothionein 2A	C00001233 C00030479
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00001233 C00030479
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00001233 C00030479
4494	MT1F, MT1	metallothionein 1F	C00001233 C00030479
4493	MT1E, MT1, MTD	metallothionein 1E	C00001233 C00030479
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00001233 C00030479
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00001233 C00030479
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001233 C00030479
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00001233 C00030479
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00001233 C00030479
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001233 C00030479
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00001233 C00030479
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00001233 C00030479
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00001233 C00030479
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00001233 C00030479
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001233 C00030479
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00001233 C00030479
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00001221 C00036669
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00001233 C00030479
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00001237 C00036669
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00001232 C00036669
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00001232 C00036669
100136658			C00001232 C00036669
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00001232 C00036669
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001180 C00001226
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00001232 C00036669
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00001233 C00030479
335	APOA1	apolipoprotein A-I	C00001232 C00036669
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00001213 C00001221
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001180 C00036669
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00001232 C00036669
199974	CYP4Z1, CYP4A20	cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1)	C00001221 C00001228
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00001226 C00036669
6502	SKP2, FBL1, FBXL1, FLB1, p45	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	C00001226
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00001226
6767	ST13, AAG2, FAM10A1, FAM10A4, HIP, HOP, HSPABP, HSPABP1, P48, PRO0786, SNC6	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	C00001226
7033	TFF3, ITF, P1B, TFI	trefoil factor 3 (intestinal)	C00001226
7082	TJP1, ZO-1	tight junction protein 1	C00001226
6286	S100P, MIG9	S100 calcium binding protein P	C00001226
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00001226
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00001226
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00001226
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00001232
123	PLIN2, ADFP, ADRP	perilipin 2	C00001226
9124	PDLIM1, CLIM1, CLP-36, CLP36, hCLIM1	PDZ and LIM domain 1	C00001226
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00001232
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00001232
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00001232
5111	PCNA	proliferating cell nuclear antigen	C00001226
100506658	OCLN, BLCPMG	occludin (EC:2.1.1.67)	C00001226
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001232
4500	MT1L, MT1, MT1R, MTF	metallothionein 1L (gene/pseudogene)	C00001226
778733			C00001232
4495	MT1G, MT1, MT1K	metallothionein 1G	C00001226
4320	MMP11, SL-3, ST3, STMY3	matrix metallopeptidase 11 (stromelysin 3) (EC:3.4.24.-)	C00001226
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00001232
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00001226
8942	KYNU	kynureninase (EC:3.7.1.3)	C00001226
6514	SLC2A2, GLUT2	solute carrier family 2 (facilitated glucose transporter), member 2	C00001232
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00001232
3726	JUNB, AP-1	jun B proto-oncogene	C00001226
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00001226
8334	HIST1H2AC, H2A/l, H2AFL, dJ221C16.4	histone cluster 1, H2ac	C00001226
3074	HEXB, ENC-1AS	hexosaminidase B (beta polypeptide) (EC:3.2.1.52)	C00001226
2869	GRK5, GPRK5	G protein-coupled receptor kinase 5 (EC:2.7.11.16)	C00001226
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00001226
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00001226
1211	CLTA, LCA	clathrin, light chain A	C00001226
7122	CLDN5, AWAL, BEC1, CPETRL1, TMVCF	claudin 5	C00001226
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00001226
898	CCNE1, CCNE	cyclin E1	C00001226
890	CCNA2, CCN1, CCNA	cyclin A2	C00001226
427	ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME	N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23)	C00001226
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00001226
350	APOH, B2G1, B2GP1, BG	apolipoprotein H (beta-2-glycoprotein I)	C00001226
1109	AKR1C4, 3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA	aldo-keto reductase family 1, member C4 (EC:1.1.1.225 1.1.1.357)	C00001226
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00001226
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00001213
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00001237
7442	TRPV1, VR1	transient receptor potential cation channel, subfamily V, member 1	C00001237
1269	CNR2, CB-2, CB2, CX5	cannabinoid receptor 2 (macrophage)	C00001237
1268	CNR1, CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR	cannabinoid receptor 1 (brain)	C00001237
64127	NOD2, ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1	nucleotide-binding oligomerization domain containing 2	C00001221
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00036669
430	ASCL2, ASH2, HASH2, MASH2, bHLHa45	achaete-scute family bHLH transcription factor 2	C00036669
1579	CYP4A11, CP4Y, CYP4A2, CYP4AII	cytochrome P450, family 4, subfamily A, polypeptide 11 (EC:1.14.15.3)	C00001221
1082	CGB, CGB3, CGB5, CGB7, CGB8, hCGB	chorionic gonadotropin, beta polypeptide	C00036669
1387	CREBBP, CBP, KAT3A, RSTS	CREB binding protein (EC:2.3.1.48)	C00036669
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00036669
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00036669
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00036669
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00036669
2168	FABP1, FABPL, L-FABP	fatty acid binding protein 1, liver	C00036669
2170	FABP3, FABP11, H-FABP, M-FABP, MDGI, O-FABP	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)	C00036669
9415	FADS2, D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13	fatty acid desaturase 2 (EC:1.14.19.-)	C00036669
3458	IFNG, IFG, IFI	interferon, gamma	C00036669
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00036669
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00036669
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00036669
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00030829
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00036669
4688	NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX	neutrophil cytosolic factor 2	C00036669
8648	NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74	nuclear receptor coactivator 1 (EC:2.3.1.48)	C00036669
10499	NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75	nuclear receptor coactivator 2	C00036669
5338	PLD2	phospholipase D2 (EC:3.1.4.4)	C00036669
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00036669
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001180
567	B2M	beta-2-microglobulin	C00001180
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001180
1081	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA	glycoprotein hormones, alpha polypeptide	C00001180
64581	CLEC7A, BGR, CANDF4, CLECSF12, DECTIN1	C-type lectin domain family 7, member A	C00001180
2002	ELK1	ELK1, member of ETS oncogene family	C00001180
8288	EPX, EPO, EPP, EPX-PEN	eosinophil peroxidase (EC:1.11.1.7)	C00001180
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00001180
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00001180
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00001180
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00001180
10013	HDAC6, CPBHM, HD6	histone deacetylase 6 (EC:3.5.1.98)	C00001180
8290	HIST3H3, H3.4, H3/g, H3FT, H3t	histone cluster 3, H3	C00001180
121504	HIST4H4, H4/p	histone cluster 4, H4	C00001180
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00001180
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00001180
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00001180
10524	KAT5, ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2	K(lysine) acetyltransferase 5 (EC:2.3.1.48)	C00001180
4254	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7	KIT ligand	C00001180
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00001180
11315	PARK7, DJ-1, DJ1	parkinson protein 7	C00001180
5553	PRG2, BMPG, MBP, MBP1	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	C00001180
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001180
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00001180
6732	SRPK1, SFRSK1	SRSF protein kinase 1 (EC:2.7.11.1)	C00001180
6733	SRPK2, SFRSK2	SRSF protein kinase 2 (EC:2.7.11.1)	C00001180
6427	SRSF2, PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b	serine/arginine-rich splicing factor 2	C00001180
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00001180
7043	TGFB3, ARVD, ARVD1, TGF-beta3	transforming growth factor, beta 3	C00001180
7096	TLR1, CD281, TIL, TIL._LPRS5, rsc786	toll-like receptor 1	C00001180
10333	TLR6, CD286	toll-like receptor 6	C00001180

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