PCIDB

KNApSAcK Metabolite C00001213

Metabolite

KNApSAcK Entry

id C00001213
Name Capric acid / Decanoic acid / n-Decanoic acid
CAS RN 334-48-5
Standard InChI InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12)
Standard InChI (Main Layer) InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12)

Cluster

Phytochemical cluster No. 68
KCF-S cluster No. 1141

Link

ChEMBL

By standard InChI CHEMBL107498
By standard InChI Main Layer CHEMBL107498

KEGG

By LinkDB C01571

CTD

By CAS RN C031071

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P22310 UDP-glucuronosyltransferase 1-4 Enzyme CHEMBL107498 CHEMBL1908081 (1)
3 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme CHEMBL107498 CHEMBL1908087 (1)
0 / 0
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL107498 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
O75496 Geminin Unclassified protein CHEMBL107498 CHEMBL2114843 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL107498 CHEMBL1794456 (1)
0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL107498 CHEMBL1794293 (1) CHEMBL1794510 (1)
5 / 3
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 CHEMBL107498 CHEMBL2114842 (1)
0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme CHEMBL107498 CHEMBL1908085 (1)
0 / 0

CTD interaction (4)

compound gene gene name gene description interaction interaction type form reference
pmid
C031071 128 ADH5
ADH-3
ADHX
FALDH
FDH
GSH-FDH
GSNOR
alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) decanoic acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] decreases reaction
/ increases reduction
protein 19428350
C031071 9076 CLDN1
CLD1
ILVASC
SEMP1
claudin 1 decanoic acid affects the localization of CLDN1 protein affects localization
protein 16566947
C031071 10891 PPARGC1A
LEM6
PGC-1(alpha)
PGC-1v
PGC1
PGC1A
PPARGC1
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha decanoic acid results in increased expression of PPARGC1A mRNA increases expression
mRNA 23056435
C031071 54659 UGT1A3
UDPGT
UDPGT_1-3
UGT-1C
UGT1-03
UGT1.3
UGT1C
UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) UGT1A3 protein results in increased glucuronidation of decanoic acid increases glucuronidation
protein 16051554

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#218800 Crigler-najjar syndrome, type i P22310
#606785 Crigler-najjar syndrome, type ii P22310
#143500 Gilbert syndrome P22310
#137800 Glioma susceptibility 1; glm1 P37231
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231

KEGG DISEASE (6)

KEGG disease name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)