Houttuynia cordata
Species
KNApSAcK Entry
| Organism name | Houttuynia cordata |
|---|---|
| Genus | Houttuynia |
| Family | Saururaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Houttuynia cordata |
|---|---|
| Linked NCBI taxonomy ID | 16752 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Saururaceae |
|---|---|
| ID | 16748 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Metabolite list (44)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003130
|
alpha.-Farnesene
/ trans-alpha-Farnesene / (E,E)-alpha-Farnesene |
C062672
|
No. 404 | No. 38 |
|
|||
|
C00003131
|
beta-Farnesene
/ (E)-beta-Farnesene / beta-trans-Farnesene |
C062671
|
No. 404 | No. 38 |
|
|||
|
C00000816
|
beta-Pinene
|
CHEMBL501351
|
C010789
|
No. 476 | No. 35 |
|
||
|
C00003110
|
Caryophyllene
/ (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene |
CHEMBL445740
CHEMBL448700 |
2 / 3 / 7 | No. 478 | No. 38 |
|
||
|
C00012483
|
Betula pubescens
/ Caryophyllene oxide / trans-Caryophyllene oxide / beta-Caryophyllene epoxide / (-)-Epoxydihydrocaryophyllene / 6,7-Epoxy-3(15)-caryophyllene / (-)-beta-Caryophyllene epoxide / 4beta,5alpha-Epoxycaryophyllene / Caryophyllene 4beta,5alpha-epoxide |
CHEMBL399036
CHEMBL508894 CHEMBL479134 CHEMBL1513806 CHEMBL1553274 |
3 / 1 / 3 | No. 500 |
|
|||
|
C00000601
|
(+)-Sesamin
|
CHEMBL43469
CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861 |
C054125
|
20 / 24 / 15 | 0 / 5 | No. 621 | No. 21 |
|
|
C00030151
|
Ethyl behenate
/ Docosanoic acid ethyl ester |
No. 627 |
|
|||||
|
C00029339
|
E-Nerolidol
/ (E)-Nerolidol / trans-Nerolidol |
CHEMBL25424
CHEMBL508801 CHEMBL561014 CHEMBL1923157 |
3 / 3 / 1 | No. 726 | No. 38 |
|
||
|
C00030224
|
Ethyl tridecanoate
|
No. 793 |
|
|||||
|
C00025788
|
Cepharadione B
|
CHEMBL396085
|
C457230
|
No. 800 |
|
|||
|
C00010868
|
D-Limonene
/ (+)-S-Carvone / d-(+)-Limonene |
CHEMBL15799
CHEMBL449062 |
7 / 21 / 48 | No. 848 | No. 35 |
|
||
|
C00030100
|
Decanol
/ 1-Decanol / n-Decanol |
CHEMBL25363
|
C029383
|
1 / 0 / 0 | 1 / 0 | No. 877 |
|
|
|
C00030153
|
Dodecene
/ n-Dodecene |
CHEMBL30959
|
1 / 0 / 0 | No. 877 |
|
|||
|
C00003047
|
Linalool
/ (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol |
CHEMBL25306
CHEMBL235672 |
C018584
|
6 / 8 / 2 | 35 / 4 | No. 958 | No. 34 |
|
|
C00000156
|
Carvacrol
|
CHEMBL281202
|
C073316
|
10 / 6 / 1 | 4 / 2 | No. 969 | No. 35 |
|
|
C00029674
|
alpha-Terpineol
|
CHEMBL447597
CHEMBL449810 |
C016775
|
3 / 16 / 11 | No. 983 | No. 35 |
|
|
|
C00001228
|
Myristic acid
/ Tetradecanoic acid / n-Tetradecanoic acid |
CHEMBL111077
|
D019814
|
17 / 9 / 10 | 3 / 0 | No. 1141 | No. 68 |
|
|
C00001213
|
Capric acid
/ Decanoic acid / n-Decanoic acid |
CHEMBL107498
|
C031071
|
8 / 11 / 6 | 4 / 0 | No. 1141 | No. 68 |
|
|
C00029455
|
2-Dodecanone
|
No. 1611 |
|
|||||
|
C00030758
|
2-Undecanone
/ Methyl nonyl ketone |
No. 1611 |
|
|||||
|
C00029545
|
4-Tridecanone
|
CHEMBL1922860
|
No. 1611 |
|
||||
|
C00000862
|
trans-beta-Ocimene
|
No. 1698 | No. 34 |
|
||||
|
C00000843
|
cis-beta-Ocimene
|
No. 1698 | No. 34 |
|
||||
|
C00029463
|
2-Nonanone
|
C026636
|
No. 1738 |
|
||||
|
C00030830
|
Nonanol
/ n-Nonanol |
CHEMBL24563
|
C014713
|
1 / 0 | No. 1749 |
|
||
|
C00030804
|
n-Decanal
|
C021170
|
2 / 0 | No. 1993 |
|
|||
|
C00030644
|
Lauraldehyde
|
No. 1993 |
|
|||||
|
C00032442
|
Undecanal
|
No. 1993 |
|
|||||
|
C00032377
|
trans-Pinocarvyl acetate
|
No. 2017 |
|
|||||
|
C00030810
|
Neodihydrocarveol
|
No. 2058 | No. 35 |
|
||||
|
C00029344
|
(Z)-2-Nonen-1-ol
|
No. 2140 |
|
|||||
|
C00003046
|
Geranyl acetate
/ trans-Geranyl acetate / Acetic acid geraniol ester |
CHEMBL1369384
|
5 / 3 / 4 | No. 2157 | No. 34 |
|
||
|
C00029544
|
4-Terpineol
/ Terpin-4-ol / Terpineol-4 / Terpinen-4-ol |
CHEMBL507795
|
C034019
|
1 / 3 / 0 | No. 2215 |
|
||
|
C00029524
|
4-Carene
|
CHEMBL326172
CHEMBL2007486 |
No. 2246 |
|
||||
|
C00000853
|
Myrcene
|
CHEMBL455491
|
C008574
|
3 / 3 / 3 | No. 2285 | No. 34 |
|
|
|
C00003060
|
alpha-Terpinene
|
No. 2468 | No. 35 |
|
||||
|
C00003061
|
gamma-Terpinene
/ 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene |
CHEMBL449693
|
C018669
|
No. 2468 | No. 35 |
|
||
|
C00029453
|
2-Decanol
/ 2-Hydroxydecane |
CHEMBL46477
|
No. 2473 |
|
||||
|
C00029452
|
2-Carene
|
No. 2690 | No. 35 |
|
||||
|
C00010344
|
Perillene
/ 3-(4-Methyl-3-pentenyl)furan |
C090823
|
No. 5618 |
|
||||
|
C00029506
|
3-Methyleneundecane
/ 3-Methylene-undecane |
No. 5852 |
|
|||||
|
C00029590
|
7-Methoxy-3,7-dimethyl-octanal
|
No. 7426 |
|
|||||
|
C00029517
|
4,4,6,6-Tetramethyl-bicyclo[3.1.0]hex-2-ene
|
No. 7602 |
|
|||||
|
C00029668
|
alpha-Cyclogeraniol acetate
|
No. 8279 |
|
Human Protein / Gene in interactions
55 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000156 C00001213 C00003047 C00029544 C00029674 | 3 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00000853 C00001228 C00003046 C00030100 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000156 C00001213 C00001228 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000156 C00003047 C00029674 | 5 / 1 |
| O75496 | Geminin | Unclassified protein | C00000601 C00001213 C00001228 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000601 C00003046 C00010868 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000601 C00001228 C00003047 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003046 C00003047 C00029339 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000156 C00001213 C00001228 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003047 C00010868 C00029339 | 3 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000853 C00001213 | 3 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00010868 C00029674 | 11 / 10 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00000156 C00003047 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000601 C00012483 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000601 C00001228 | 2 / 3 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000601 C00012483 | 1 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000601 C00001228 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000853 C00001213 | 0 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000601 C00029339 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000601 C00012483 | 0 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000601 C00001228 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000601 C00001228 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000601 | 2 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000156 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000156 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001228 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000601 | 7 / 3 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001228 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001228 | 2 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003046 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00001228 | 2 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001213 | 5 / 3 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000156 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000601 | 0 / 0 |
| O75762 | Transient receptor potential cation channel subfamily A member 1 | Unclassified protein | C00000156 | 1 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000601 | 2 / 2 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00001213 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000601 | 0 / 0 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00010868 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00010868 | 0 / 0 |
| Q05193 | Dynamin-1 | Structural | C00001228 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00010868 | 0 / 3 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000601 | 4 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000601 | 0 / 0 |
| O60603 | Toll-like receptor 2 | Membrane receptor | C00001228 | 1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000601 | 4 / 3 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000156 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00010868 | 7 / 37 |
| P10275 | Androgen receptor | NR3C4 | C00003046 | 3 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001228 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00030153 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001228 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00003110 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003110 | 1 / 2 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000601 | 1 / 0 |
49 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00001213
C00001228
|
| 3638 | INSIG1, CL-6, CL6 | insulin induced gene 1 |
C00003047
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00003047
|
| 1386 | ATF2, CRE-BP1, CREB2, HB16, TREB7 | activating transcription factor 2 (EC:2.3.1.48) |
C00003047
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00003047
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00003047
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00003047
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00003047
|
| 1028 | CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2 | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
C00003047
|
| 1030 | CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
C00003047
|
| 1447 | CSN2, CASB | casein beta |
C00003047
|
| 1509 | CTSD, CLN10, CPSD | cathepsin D (EC:3.4.23.5) |
C00003047
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003047
|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00003047
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00003047
|
| 2335 | FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF | fibronectin 1 |
C00003047
|
| 1647 | GADD45A, DDIT1, GADD45 | growth arrest and DNA-damage-inducible, alpha |
C00003047
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00003047
|
| 3156 | HMGCR, LDLCQ3 | 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) |
C00003047
|
| 3297 | HSF1, HSTF1 | heat shock transcription factor 1 |
C00003047
|
| 3320 | HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
C00003047
|
| 3308 | HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY | heat shock 70kDa protein 4 |
C00003047
|
| 3316 | HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP | heat shock 27kDa protein 2 |
C00003047
|
| 3398 | ID2, GIG8, ID2A, ID2H, bHLHb26 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
C00003047
|
| 1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00003047
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00003047
|
| 8850 | KAT2B, CAF, P, P/CAF, PCAF | K(lysine) acetyltransferase 2B (EC:2.3.1.48) |
C00003047
|
| 4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00003047
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00003047
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00003047
|
| 4852 | NPY, PYY4 | neuropeptide Y |
C00003047
|
| 100124292 |
C00003047
|
||
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00003047
|
| 7295 | TXN, TRDX, TRX, TRX1 | thioredoxin |
C00003047
|
| 7471 | WNT1, BMND16, INT1, OI15 | wingless-type MMTV integration site family, member 1 |
C00003047
|
| 26118 | WSB1, SWIP1, WSB-1 | WD repeat and SOCS box containing 1 |
C00003047
|
| 231 | AKR1B1, ADR, ALDR1, ALR2, AR | aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) |
C00030804
|
| 217 | ALDH2, ALDH-E2, ALDHI, ALDM | aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) |
C00030804
|
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00030100
|
| 128 | ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR | alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) |
C00001213
|
| 9076 | CLDN1, CLD1, ILVASC, SEMP1 | claudin 1 |
C00001213
|
| 9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00030830
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00001213
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000156
|
| 8989 | TRPA1, ANKTM1, FEPS | transient receptor potential cation channel, subfamily A, member 1 |
C00000156
|
| 162514 | TRPV3, OLMS, VRL3 | transient receptor potential cation channel, subfamily V, member 3 |
C00000156
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00000156
|
| 199974 | CYP4Z1, CYP4A20 | cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1) |
C00001228
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00001228
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (71)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| %606641 | Body mass index; bmi |
P37231
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615040 | Episodic pain syndrome, familial, 1; feps1 |
O75762
|
| #133239 | Esophageal cancer |
P04637
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #246300 | Leprosy, susceptibility to, 3; lprs3 |
O60603
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #601665 | Obesity |
P37231
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (82)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00344 | Leprosy |
O60603
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
11 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D017453 | Dermatitis, Irritant |
C00003047
|
| D006937 | Hypercholesterolemia |
C00003047
|
| D007938 | Leukemia |
C00003047
|
| D009369 | Neoplasms |
C00003047
|
| D001930 | Brain Injuries |
C00000601
|
| D002375 | Catalepsy |
C00000601
|
| D018476 | Hypokinesia |
C00000601
|
| D020244 | Infarction, Middle Cerebral Artery |
C00000601
|
| D020734 | Parkinsonian Disorders |
C00000601
|
| D003866 | Depressive Disorder |
C00000156
|
| D010146 | Pain |
C00000156
|