KCF-S cluster No. 404 (18 metabolites)

Corresponding Phytochemical cluster No. 38

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (18)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	19
rosids	17
Magnoliophyta	9
Liliopsida	4
Embryophyta	3
eudicotyledons	2
Spermatophyta	1

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Cumulative family count (Top 20)

class name	count
Rutaceae	9
Asteraceae	9
Solanaceae	7
Saururaceae	4
Formicidae	4
Zingiberaceae	3
Lamiaceae	3
Frullaniaceae	3
Malvaceae	2
Fagaceae	2
Rosaceae	2
Lauraceae	2
Alligatoridae	2
Cistaceae	1
Piperaceae	1
Annonaceae	1
Ganodermataceae	1
Santalaceae	1
Magnoliaceae	1
Brassicaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Farnesenes	5

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metabolites link (5)

br08003 Category	KEGG ID	KNApSAcK ID
Farnesenes	C09665	C00003130
Farnesenes	C09666	C00003131
Farnesenes	C01493	C00003132
Farnesenes	C03461	C00035091
Farnesenes	C01126	C00035092

Metabolite list (18)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003130	alpha.-Farnesene / trans-alpha-Farnesene / (E,E)-alpha-Farnesene		C062672
C00003131	beta-Farnesene / (E)-beta-Farnesene / beta-trans-Farnesene		C062671
C00003132	trans,trans-Farnesol	CHEMBL25308 CHEMBL488357	D005204	7 / 7 / 11	14 / 4
C00011403	(Z,E)-3,4,7,11-Tetramethyl-1,3,6,10-dodecatetraene
C00011404	(Z,Z)- 3,4,7,11-Tetramethyl-1,3,6,10-dodecatetraene
C00011414	(E,E,E)-3,7,11-trimethyl-2,4,6,10-Dodecatetraene
C00011415	(E,E,Z)-3,7,11-trimethyl-2,4,6,10-Dodecatetraene
C00011422	2,6,10-Trimethyl-2,6,10-dodecatriene
C00011511	10-Sesquigeranic acid
C00022165	4,8,12-Trimethyl-1,3E,7E,11-tridecatetraene / (E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene
C00029350	Z-beta-Farnesene / (Z)-beta-Farnesene / beta-cis-Farnesene / cis-beta-Farnesene
C00030246	Farnesal		C084519		5 / 0
C00035091	E,E-Farnesal / trans,trans-Farnesal
C00035092	E,E-Farnesol	CHEMBL25308 CHEMBL488357		7 / 7 / 11
C00035167	Zataroside A
C00036247	(E,Z)-alpha-Farnesene
C00044405	(2E)-Farnesylamine
C00044406	(2Z)-Farnesylamine

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003132 C00035092	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003132 C00035092	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003132 C00035092	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00003132 C00035092	4 / 3
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003132 C00035092	0 / 0
O00255	Menin	Unclassified protein	C00003132 C00035092	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003132 C00035092	1 / 2

17 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00003132 C00030246
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00003132 C00030246
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00003132
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00030246
4502	MT2A, MT2	metallothionein 2A	C00030246
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003132
100328933			C00003132
9971	NR1H4, BAR, FXR, HRR-1, HRR1, RIP14	nuclear receptor subfamily 1, group H, member 4	C00003132
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00030246
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00003132
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00003132
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00003132
54657	UGT1A4, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D	UDP glucuronosyltransferase 1 family, polypeptide A4 (EC:2.4.1.17)	C00003132
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00003132
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00003132
7363	UGT2B4, HLUG25, UDPGT2B4, UDPGTH1, UGT2B11	UDP glucuronosyltransferase 2 family, polypeptide B4 (EC:2.4.1.17)	C00003132
7364	UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9	UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17)	C00003132

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions