Sebertia acuminata

• Index
• Plant Species
• Metabolite list (30)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Sebertia acuminata
Genus	Sebertia
Family	Sapotaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Pycnandra acuminata
Linked NCBI taxonomy ID	280718
Linked level	species

Family

Family in NCBI taxonomy	Sapotaceae
ID	3737

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (30)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003738	beta-Amyrin / beta-Amirin / beta-Amyrine / beta-Amyrenol		C036380		0 / 4	No. 23	No. 51
C00003674	Stigmasterol / beta-Stigmasterol	CHEMBL66943 CHEMBL186373 CHEMBL400247 CHEMBL1568947	D013265	5 / 0 / 0	1 / 0	No. 53	No. 11
C00034311	Tetracosanol / n-Tetracosanol / Lignoceric alcohol					No. 115
C00001164	Myoinositol / myo-Inositol	CHEMBL278373 CHEMBL468154 CHEMBL1222251 CHEMBL1231671 CHEMBL1950780		8 / 17 / 18		No. 795
C00033542	beta-Resorcylic acid / 2,4-Dihydroxybenzoic acid	CHEMBL328910	C017704	23 / 17 / 17		No. 817	No. 81
C00001213	Capric acid / Decanoic acid / n-Decanoic acid	CHEMBL107498	C031071	8 / 11 / 6	4 / 0	No. 1141	No. 68
C00007366	alpha-Tocopherol	CHEMBL47 CHEMBL49563 CHEMBL442800	D024502	99 / 57 / 52	54 / 55	No. 1290
C00034344	Xylose / D-(+)-Xylose					No. 1384
C00033848	Fructose / D-Fructose / D-(-)-Fructose	CHEMBL23894 CHEMBL1869413		9 / 4 / 3		No. 1614
C00019674	Uridine	CHEMBL68846 CHEMBL100259 CHEMBL265701 CHEMBL608294 CHEMBL609651 CHEMBL1092065 CHEMBL2093066	D014529	5 / 0 / 3	7 / 15	No. 2366
C00000769	alpha-Oxoglutaric acid / alpha-Ketoglutaric acid	CHEMBL1686	C029743	13 / 6 / 7	8 / 0	No. 2414
C00001200	Pyruvic acid	CHEMBL1162144	D019289	5 / 2 / 2	10 / 4	No. 2782
C00034313	Threitol / DL-Tetritol	CHEMBL349605 CHEMBL402812	C003460	3 / 5 / 5		No. 2923
C00034205	Saccharic acid / D-(+)-Saccharic acid					No. 3032
C00033561	3-Deoxy-arabino-hexaric acid / 3-Deoxy-D-arabino-Hexaric acid					No. 3032
C00007303	D-Gluconate / Gluconic acid / D-Gluconic acid	CHEMBL464345	C030691		1 / 2	No. 3032
C00034185	Quinic acid	CHEMBL444501 CHEMBL465398		5 / 1 / 3		No. 3541
C00001180	Butyric acid	CHEMBL14227	D020148	12 / 3 / 2	40 / 5	No. 3692	No. 68
C00001183	Fumaric acid	CHEMBL503160 CHEMBL539648	C032005	17 / 14 / 46	0 / 1	No. 3766
C00001151	Sucrose / (+)-Sucrose	CHEMBL253582 CHEMBL1976550	D013395	1 / 0 / 0	4 / 10	No. 3949
C00034314	Threonic acid	CHEMBL2152047	C011369			No. 4711
C00033834	Erythronic acid	CHEMBL2152047				No. 4711
C00033555	2-Methyl-1,3-butanediol					No. 5183
C00033964	Itaconic acid	CHEMBL359159	C005229	1 / 1 / 5		No. 5305
C00001205	Succinic acid	CHEMBL576	D019802	6 / 13 / 17	1 / 3	No. 5377
C00001163	Glycerol	CHEMBL692	D005990	8 / 15 / 11	10 / 18	No. 5926
C00034315	Threonic acid 1-4-lactone	CHEMBL113716				No. 7085
C00007619	Citric acid	CHEMBL1261	D019343	101 / 48 / 38	15 / 7	No. 7422
C00033553	2-Keto-L-gluconic acid / L-arabino-2-Hexulosonic acid					No. 7436
C00034296	Succinic anhydride / Tetrahydro-2,5-furandione	CHEMBL1370164	C031801	3 / 3 / 3		No. 8905

Human Protein / Gene in interactions

183 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00001164 C00001183 C00001213 C00019674 C00033542 C00033848 C00034185 C00034296	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000769 C00001163 C00001183 C00007619 C00033542	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00001183 C00007366 C00007619 C00033542 C00034313	1 / 2
P04150	Glucocorticoid receptor	NR3C1	C00001213 C00007366 C00007619 C00034296	0 / 1
P02545	Prelamin-A/C	Unclassified protein	C00001163 C00001164 C00001205 C00007366	11 / 10
P16473	Thyrotropin receptor	Glycohormone receptor	C00001183 C00001213 C00033542 C00034296	3 / 2
O75164	Lysine-specific demethylase 4A	Enzyme	C00001183 C00007619 C00033848 C00034185	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00007366 C00007619 C00019674 C00034185	0 / 3
Q9GZT9	Egl nine homolog 1	Enzyme	C00000769 C00001183 C00001205 C00007619	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00001163 C00007619 C00033542	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00001163 C00007366 C00007619	3 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00000769 C00007366 C00007619	0 / 0
P03956	Interstitial collagenase	M10A	C00007366 C00007619 C00033542	0 / 1
Q9C0B1	Alpha-ketoglutarate-dependent dioxygenase FTO	Unclassified protein	C00001183 C00001200 C00007619	1 / 2
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001213 C00007619 C00033542	5 / 3
P14780	Matrix metalloproteinase-9	M10A	C00007366 C00007619 C00033542	2 / 2
P10323	Acrosin	S1A	C00001163 C00001164 C00033848	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00007366 C00007619	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00007366 C00007619	0 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00007366 C00007619	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00007366 C00007619	1 / 1
P10275	Androgen receptor	NR3C4	C00000769 C00033542	3 / 4
Q16539	Mitogen-activated protein kinase 14	p38	C00007366 C00007619	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001183 C00007366	0 / 0
P29466	Caspase-1	C14	C00007366 C00007619	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00007366 C00007619	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00007366 C00007619	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00001163 C00033542	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00007366 C00007619	0 / 0
P08246	Neutrophil elastase	S1A	C00007366 C00007619	2 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00001164 C00019674	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00007366 C00007619	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00007366 C00007619	0 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00007366 C00007619	2 / 2
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00007366 C00007619	1 / 1
P33032	Melanocortin receptor 5	Melanocortin receptor	C00007366 C00007619	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00007366 C00007619	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00007366 C00007619	0 / 0
Q16798	NADP-dependent malic enzyme, mitochondrial	Enzyme	C00001183 C00001205	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00007366 C00007619	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00007366 C00007619	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00007366 C00007619	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00007366 C00007619	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00007366 C00007619	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00007366 C00007619	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00007366 C00007619	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00007366 C00007619	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00007366 C00007619	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00007366 C00007619	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00007366 C00007619	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00007366 C00007619	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000769 C00001163	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00007366 C00007619	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00007366 C00007619	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00007366 C00007619	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00007366 C00007619	0 / 1
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00007366 C00007619	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00007366 C00007619	1 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00007366 C00007619	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00007366 C00007619	1 / 8
P22303	Acetylcholinesterase	Hydrolase	C00007366 C00007619	1 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00007366 C00007619	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00007366 C00007619	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00007366 C00007619	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00007366 C00007619	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00007366 C00007619	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00007366 C00007619	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00007366 C00007619	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00007366 C00007619	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00007366 C00007619	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00007366 C00007619	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00007366 C00007619	1 / 0
P03372	Estrogen receptor	NR3A1	C00007366 C00007619	1 / 1
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00007366 C00007619	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00001180 C00001213	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00001180 C00001213	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001183 C00033542	0 / 0
Q00987	E3 ubiquitin-protein ligase Mdm2	Other nuclear protein	C00001205 C00033964	1 / 5
Q16790	Carbonic anhydrase 9	Lyase	C00033542 C00034313	0 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00007366 C00007619	0 / 0
Q7Z4W1	L-xylulose reductase	Enzyme	C00001180 C00001205	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00007366 C00007619	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00007366 C00007619	2 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00007366 C00007619	0 / 1
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00000769 C00001205	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00007366 C00007619	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00007366 C00007619	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00007366 C00007619	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00007366 C00007619	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00007366 C00007619	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00007366 C00007619	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00007366 C00007619	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00007366 C00007619	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00007366 C00007619	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00007366 C00007619	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00007366 C00007619	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00007366 C00007619	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00001183 C00033542	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00007366 C00007619	0 / 0
P08311	Cathepsin G	S1A	C00007366 C00007619	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00007366 C00007619	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00007366 C00033848	0 / 0
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00007366 C00007619	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00007366 C00007619	1 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00007366 C00007619	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001183 C00033542	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00007366 C00007619	3 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00033542 C00033848	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00007366 C00007619	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00007366 C00007619	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00007366 C00007619	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00007366 C00007619	2 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00007366 C00007619	1 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00007366 C00007619	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00007366 C00007619	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00007366 C00007619	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00007366 C00007619	1 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00007619	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00007366	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00000769	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00001164	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00007619	0 / 0
O15379	Histone deacetylase 3	Hydrolase	C00001180	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00001183	1 / 2
Q9HA47	Uridine-cytidine kinase 1	Enzyme	C00019674	0 / 0
Q9NWT6	Hypoxia-inducible factor 1-alpha inhibitor	Enzyme	C00000769	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00033848	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00001183	0 / 0
Q9UQL6	Histone deacetylase 5	Hydrolase	C00001180	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00033542	1 / 3
O43570	Carbonic anhydrase 12	Lyase	C00033542	1 / 2
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00001213	0 / 0
P16581	E-selectin	Adhesion	C00034185	0 / 0
Q92769	Histone deacetylase 2	Hydrolase	C00001180	0 / 0
P27708	CAD protein	Enzyme	C00019674	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00033542	0 / 0
Q96KS0	Egl nine homolog 2	Enzyme	C00000769	0 / 0
P09884	DNA polymerase alpha catalytic subunit	Transferase	C00003674	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00033848	2 / 3
P13674	Prolyl 4-hydroxylase subunit alpha-1	Enzyme	C00000769	0 / 0
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00007366	0 / 0
Q9BY41	Histone deacetylase 8	Hydrolase	C00001180	2 / 0
P02768	Serum albumin	Secreted protein	C00001151	0 / 0
P16278	Beta-galactosidase	Enzyme	C00001164	4 / 6
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00003674	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00034313	4 / 2
P56524	Histone deacetylase 4	Hydrolase	C00001180	1 / 1
Q8WUI4	Histone deacetylase 7	Hydrolase	C00001180	0 / 0
P16109	P-selectin	Adhesion	C00034185	1 / 0
Q9Y694	Solute carrier family 22 member 7	Unclassified protein	C00000769	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00007366	0 / 0
P41235	Hepatocyte nuclear factor 4-alpha	Unclassified protein	C00007619	3 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00033848	0 / 0
Q13547	Histone deacetylase 1	Hydrolase	C00001180	0 / 0
Q16773	Kynurenine--oxoglutarate transaminase 1	Enzyme	C00001163	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00007366	4 / 3
P22894	Neutrophil collagenase	M10A	C00033542	0 / 0
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00001164	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00033542	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00001183	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00001183	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003674	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00033542	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00033848	2 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00007619	0 / 0
O60240	Perilipin-1	Unclassified protein	C00007619	1 / 0
P08254	Stromelysin-1	M10A	C00033542	1 / 0
Q9UBN7	Histone deacetylase 6	Hydrolase	C00001180	0 / 0
Q9UKV0	Histone deacetylase 9	Hydrolase	C00001180	0 / 0
Q9H6Z9	Egl nine homolog 3	Enzyme	C00000769	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00033542	1 / 0
O00255	Menin	Unclassified protein	C00007366	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00007366	1 / 2
O15427	Monocarboxylate transporter 4	Unclassified protein	C00001200	0 / 0
O76082	Solute carrier family 22 member 5	Unclassified protein	C00000769	1 / 2
Q92959	Solute carrier organic anion transporter family member 2A1	Unclassified protein	C00001200	1 / 0
O60669	Monocarboxylate transporter 2	Unclassified protein	C00001200	0 / 0
Q05BR4	SLC16A10 protein	Unclassified protein	C00001200	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003674	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00003674	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00001183	7 / 37
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00001213	3 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001164	1 / 1

132 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00001180 C00007366 C00007619
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001163 C00001180 C00019674
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001180 C00001200 C00007366
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001200 C00001213
11315	PARK7, DJ-1, DJ1	parkinson protein 7	C00001180 C00007366
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00001180 C00007366
9356	SLC22A6, HOAT1, OAT1, PAHT, ROAT1	solute carrier family 22 (organic anion transporter), member 6	C00000769 C00007303
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001180 C00007366
7015	TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT	telomerase reverse transcriptase (EC:2.7.7.49)	C00007366 C00007619
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001180 C00007619
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00001180 C00007366
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00007366 C00007619
335	APOA1	apolipoprotein A-I	C00001163 C00007366
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00007366 C00007619
8290	HIST3H3, H3.4, H3/g, H3FT, H3t	histone cluster 3, H3	C00000769 C00001180
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00001163 C00007366
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001180 C00007366
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00001180 C00019674
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001180 C00007366
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00001163 C00007366
847	CAT	catalase (EC:1.11.1.6)	C00007366
4878	NPPA, ANF, ANP, ATFB6, CDD-ANF, PND	natriuretic peptide A	C00001163
10599	SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6	solute carrier organic anion transporter family, member 1B1	C00003674
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001151
55630	SLC39A4, AEZ, AWMS2, ZIP4	solute carrier family 39 (zinc transporter), member 4	C00001151
80834	TAS1R2, GPR71, T1R2, TR2	taste receptor, type 1, member 2	C00001151
83756	TAS1R3, T1R3	taste receptor, type 1, member 3	C00001151
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00019674
4502	MT2A, MT2	metallothionein 2A	C00001163
9154	SLC28A1, CNT1, HCNT1	solute carrier family 28 (concentrative nucleoside transporter), member 1	C00019674
9153	SLC28A2, CNT2, HCNT2, HsT17153, SPNT1	solute carrier family 28 (concentrative nucleoside transporter), member 2	C00019674
2030	SLC29A1, ENT1	solute carrier family 29 (equilibrative nucleoside transporter), member 1	C00019674
3177	SLC29A2, DER12, ENT2, HNP36	solute carrier family 29 (equilibrative nucleoside transporter), member 2	C00019674
31	ACACA, ACAC, ACACAD, ACC, ACC1, ACCA	acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14)	C00001200
1487	CTBP1, BARS	C-terminal binding protein 1	C00001200
1488	CTBP2	C-terminal binding protein 2	C00001200
1586	CYP17A1, CPT7, CYP17, P450C17, S17AH	cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30)	C00001200
14103			C00001200
2516	NR5A1, AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3	nuclear receptor subfamily 5, group A, member 1	C00001200
23411	SIRT1, SIR2L1	sirtuin 1	C00001200
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00001200
4489	MT1A, MT1, MT1S, MTC	metallothionein 1A	C00001163
50	ACO2, ACONM, ICRD	aconitase 2, mitochondrial (EC:4.2.1.3)	C00007619
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001163
89872	AQP10, AQPA_HUMAN	aquaporin 10	C00001163
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00007619
100506742	CASP12, CASP-12, CASP12P1	caspase 12 (gene/pseudogene)	C00007619
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00001213
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00001213
2746	GLUD1, GDH, GDH1, GLUD	glutamate dehydrogenase 1 (EC:1.4.1.3)	C00007619
25818	KLK5, KLK-L2, KLKL2, SCTE	kallikrein-related peptidase 5	C00007619
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00007619
9058	SLC13A2, NADC1, NaCT, NaDC-1, SDCT1	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	C00007619
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00001213
7018	TF, PRO1557, PRO2086, TFQTL1	transferrin	C00007619
7442	TRPV1, VR1	transient receptor potential cation channel, subfamily V, member 1	C00007619
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00007619
64849	SLC13A3, NADC3, SDCT2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	C00001205
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001180
567	B2M	beta-2-microglobulin	C00001180
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00001180
1081	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA	glycoprotein hormones, alpha polypeptide	C00001180
64581	CLEC7A, BGR, CANDF4, CLECSF12, DECTIN1	C-type lectin domain family 7, member A	C00001180
2002	ELK1	ELK1, member of ETS oncogene family	C00001180
8288	EPX, EPO, EPP, EPX-PEN	eosinophil peroxidase (EC:1.11.1.7)	C00001180
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00001180
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00001180
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00001180
10013	HDAC6, CPBHM, HD6	histone deacetylase 6 (EC:3.5.1.98)	C00001180
121504	HIST4H4, H4/p	histone cluster 4, H4	C00001180
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00001180
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00001180
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001180
7428	VHL, HRCA1, RCA1, VHL1, pVHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	C00000769
54681	P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	C00000769
10524	KAT5, ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2	K(lysine) acetyltransferase 5 (EC:2.3.1.48)	C00001180
4254	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7	KIT ligand	C00001180
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00001180
55818	KDM3A, JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA	lysine (K)-specific demethylase 3A	C00000769
8424	BBOX1, BBH, BBOX, G-BBH, gamma-BBH	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (EC:1.14.11.1)	C00000769
5553	PRG2, BMPG, MBP, MBP1	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	C00001180
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001180
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00000769
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00001180
6732	SRPK1, SFRSK1	SRSF protein kinase 1 (EC:2.7.11.1)	C00001180
6733	SRPK2, SFRSK2	SRSF protein kinase 2 (EC:2.7.11.1)	C00001180
6427	SRSF2, PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b	serine/arginine-rich splicing factor 2	C00001180
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00001180
7043	TGFB3, ARVD, ARVD1, TGF-beta3	transforming growth factor, beta 3	C00001180
7096	TLR1, CD281, TIL, TIL._LPRS5, rsc786	toll-like receptor 1	C00001180
10333	TLR6, CD286	toll-like receptor 6	C00001180
728294	D2HGDH, D2HGD	D-2-hydroxyglutarate dehydrogenase (EC:1.1.99.-)	C00000769
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00007366
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00007366
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00007366
23621	BACE1, ASP2, BACE, HSPC104	beta-site APP-cleaving enzyme 1 (EC:3.4.23.46)	C00007366
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00007366
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00007366
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00007366
5443	POMC, ACTH, CLIP, LPH, MSH, NPP, POC	proopiomelanocortin	C00001163
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00007366
1382	CRABP2, CRABP-II, RBP6	cellular retinoic acid binding protein 2	C00007366
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00007366
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00007366
83939	EIF2A, EIF-2A, MST089, MSTP004, MSTP089	eukaryotic translation initiation factor 2A, 65kDa	C00007366
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00007366
2534	FYN, SLK, SYN, p59-FYN	FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2)	C00007366
2879	GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx	glutathione peroxidase 4 (EC:1.11.1.12)	C00007366
3048	HBG2, TNCY	hemoglobin, gamma G	C00007366
3240	HP, BP, HP2ALPHA2, HPA1S	haptoglobin	C00007366
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00007366
3932	LCK, LSK, YT16, p56lck, pp58lck	lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2)	C00007366
4067	LYN, JTK8, p53Lyn, p56Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2)	C00007366
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00007366
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00007366
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00007366
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00007366
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00007366
4155	MBP	myelin basic protein	C00007366
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00007366
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00007366
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00007366
5230	PGK1, MIG10, PGKA	phosphoglycerate kinase 1 (EC:2.7.2.3)	C00007366
5340	PLG	plasminogen (EC:3.4.21.7)	C00007366
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00007366
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00007366
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00007366
4089	SMAD4, DPC4, JIP, MADH4, MYHRS	SMAD family member 4	C00007366
6622	SNCA, NACP, PARK1, PARK4, PD1	synuclein, alpha (non A4 component of amyloid precursor)	C00007366
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00007366
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00007366
7494	XBP1, TREB5, XBP-1, XBP2	X-box binding protein 1	C00007366

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