id | C00001180 |
---|---|
Name | Butyric acid |
CAS RN | 107-92-6 |
Standard InChI | InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) |
Standard InChI (Main Layer) | InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) |
Phytochemical cluster | No. 68 |
---|---|
KCF-S cluster | No. 3692 |
By standard InChI | CHEMBL14227 |
---|---|
By standard InChI Main Layer | CHEMBL14227 |
By LinkDB | C00246 |
---|
By CAS RN | D020148 |
---|
family name | count |
---|---|
Vitaceae | 1 |
Brassicaceae | 1 |
Sapotaceae | 1 |
KNApSAcK organism | *ID | *family | *plant class | *kingdom |
---|---|---|---|---|
Brassica hirta | 3728 | Brassicaceae | rosids | Viridiplantae |
Sebertia acuminata | 280718 | Sapotaceae | asterids | Viridiplantae |
Vitis vinifera | 29760 | Vitaceae | rosids | Viridiplantae |
accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|---|
Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | CHEMBL14227 |
CHEMBL1908087
(1)
|
0 / 0 |
Q13547 | Histone deacetylase 1 | Hydrolase | CHEMBL14227 |
CHEMBL1680132
(1)
|
0 / 0 |
Q9BY41 | Histone deacetylase 8 | Hydrolase | CHEMBL14227 |
CHEMBL1680135
(1)
|
2 / 0 |
Q92769 | Histone deacetylase 2 | Hydrolase | CHEMBL14227 |
CHEMBL1680133
(1)
|
0 / 0 |
Q9UQL6 | Histone deacetylase 5 | Hydrolase | CHEMBL14227 |
CHEMBL1680137
(1)
|
0 / 0 |
O15379 | Histone deacetylase 3 | Hydrolase | CHEMBL14227 |
CHEMBL1680134
(1)
|
0 / 0 |
Q7Z4W1 | L-xylulose reductase | Enzyme | CHEMBL14227 |
CHEMBL706159
(1)
|
0 / 1 |
Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | CHEMBL14227 |
CHEMBL1908085
(1)
|
0 / 0 |
P56524 | Histone deacetylase 4 | Hydrolase | CHEMBL14227 |
CHEMBL1680136
(1)
|
1 / 1 |
Q8WUI4 | Histone deacetylase 7 | Hydrolase | CHEMBL14227 |
CHEMBL1680138
(1)
|
0 / 0 |
Q9UBN7 | Histone deacetylase 6 | Hydrolase | CHEMBL14227 |
CHEMBL1680140
(1)
CHEMBL1680141
(1)
|
0 / 0 |
Q9UKV0 | Histone deacetylase 9 | Hydrolase | CHEMBL14227 |
CHEMBL1680139
(1)
|
0 / 0 |
compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
---|---|---|---|---|---|---|---|
D020148 | 5243 |
ABCB1
ABC20 CD243 CLCS GP170 MDR1 P-GP PGY1 |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) | Butyric Acid results in increased expression of ABCB1 mRNA |
increases expression
|
mRNA |
15711177
|
D020148 | 567 |
B2M
|
beta-2-microglobulin | Butyric Acid results in decreased stability of B2M mRNA |
decreases stability
|
mRNA |
1693837
|
D020148 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | Butyric Acid results in increased expression of BAX protein |
increases expression
|
protein |
11964082
|
D020148 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | Butyric Acid results in increased expression of CCL2 mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Butyric Acid results in increased expression of CDKN1A protein |
increases expression
|
protein |
15715472
|
D020148 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | [Butyric Acid results in increased expression of SRSF2 protein] which results in increased expression of CDKN1A mRNA |
increases expression
|
mRNA |
21555914
|
D020148 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | [Butyric Acid results in increased expression of SRSF2 protein] which results in increased expression of CDKN1A protein |
increases expression
|
protein |
21555914
|
D020148 | 1081 |
CGA
CG-ALPHA FSHA GPHA1 GPHa HCG LHA TSHA |
glycoprotein hormones, alpha polypeptide | Butyric Acid results in decreased stability of CGA mRNA |
decreases stability
|
mRNA |
1693837
|
D020148 | 1081 |
CGA
CG-ALPHA FSHA GPHA1 GPHa HCG LHA TSHA |
glycoprotein hormones, alpha polypeptide | Butyric Acid results in increased expression of CGA mRNA |
increases expression
|
mRNA |
1693837
|
D020148 | 1081 |
CGA
CG-ALPHA FSHA GPHA1 GPHa HCG LHA TSHA |
glycoprotein hormones, alpha polypeptide | Butyric Acid results in increased expression of CGA protein |
increases expression
|
protein |
1693836
1693837 |
D020148 | 1081 |
CGA
CG-ALPHA FSHA GPHA1 GPHa HCG LHA TSHA |
glycoprotein hormones, alpha polypeptide | [Theophylline co-treated with Butyric Acid] results in increased expression of CGA mRNA |
affects cotreatment
/ increases expression |
mRNA |
1693836
|
D020148 | 1081 |
CGA
CG-ALPHA FSHA GPHA1 GPHa HCG LHA TSHA |
glycoprotein hormones, alpha polypeptide | Theophylline inhibits the reaction [Butyric Acid results in decreased stability of CGA mRNA] |
decreases reaction
/ decreases stability |
mRNA |
1693837
|
D020148 | 1081 |
CGA
CG-ALPHA FSHA GPHA1 GPHa HCG LHA TSHA |
glycoprotein hormones, alpha polypeptide | Theophylline promotes the reaction [Butyric Acid results in increased expression of CGA protein] |
increases expression
/ increases reaction |
protein |
1693836
1693837 |
D020148 | 64581 |
CLEC7A
BGR CANDF4 CLECSF12 DECTIN1 |
C-type lectin domain family 7, member A | Butyric Acid results in increased expression of CLEC7A mRNA |
increases expression
|
mRNA |
15196572
|
D020148 | 2002 |
ELK1
|
ELK1, member of ETS oncogene family | Butyric Acid results in increased activity of ELK1 protein |
increases activity
|
protein |
15103026
|
D020148 | 2002 |
ELK1
|
ELK1, member of ETS oncogene family | U 0126 inhibits the reaction [Butyric Acid results in increased activity of ELK1 protein] |
decreases reaction
/ increases activity |
protein |
15103026
|
D020148 | 8288 |
EPX
EPO EPP EPX-PEN |
eosinophil peroxidase (EC:1.11.1.7) | Butyric Acid results in increased expression of EPX protein |
increases expression
|
protein |
14769150
|
D020148 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Butyric Acid promotes the reaction [Estradiol results in increased activity of ESR2 protein] |
increases activity
/ increases reaction |
protein |
15103026
|
D020148 | 2623 |
GATA1
ERYF1 GATA-1 GF-1 GF1 NF-E1 NFE1 XLANP XLTDA XLTT |
GATA binding protein 1 (globin transcription factor 1) | Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 2623 |
GATA1
ERYF1 GATA-1 GF-1 GF1 NF-E1 NFE1 XLANP XLTDA XLTT |
GATA binding protein 1 (globin transcription factor 1) | Butyric Acid results in increased expression of GATA1 mRNA |
increases expression
|
mRNA |
10656287
14757314 |
D020148 | 2623 |
GATA1
ERYF1 GATA-1 GF-1 GF1 NF-E1 NFE1 XLANP XLTDA XLTT |
GATA binding protein 1 (globin transcription factor 1) | chebulinic acid inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
14769215
|
D020148 | 2623 |
GATA1
ERYF1 GATA-1 GF-1 GF1 NF-E1 NFE1 XLANP XLTDA XLTT |
GATA binding protein 1 (globin transcription factor 1) | pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 2623 |
GATA1
ERYF1 GATA-1 GF-1 GF1 NF-E1 NFE1 XLANP XLTDA XLTT |
GATA binding protein 1 (globin transcription factor 1) | Quercetin inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 2623 |
GATA1
ERYF1 GATA-1 GF-1 GF1 NF-E1 NFE1 XLANP XLTDA XLTT |
GATA binding protein 1 (globin transcription factor 1) | tellimagrandin I inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
14757314
|
D020148 | 2624 |
GATA2
DCML MONOMAC NFE1B |
GATA binding protein 2 | Butyric Acid results in increased expression of GATA2 mRNA |
increases expression
|
mRNA |
14757314
|
D020148 | 2624 |
GATA2
DCML MONOMAC NFE1B |
GATA binding protein 2 | chebulinic acid promotes the reaction [Butyric Acid results in increased expression of GATA2 mRNA] |
increases expression
/ increases reaction |
mRNA |
14769215
|
D020148 | 2624 |
GATA2
DCML MONOMAC NFE1B |
GATA binding protein 2 | tellimagrandin I promotes the reaction [Butyric Acid results in increased expression of GATA2 mRNA] |
increases expression
/ increases reaction |
mRNA |
14757314
|
D020148 | 2993 |
GYPA
CD235a GPA GPErik GPSAT HGpMiV HGpMiXI HGpSta(C) MN MNS PAS-2 |
glycophorin A (MNS blood group) | Butyric Acid results in increased expression of GYPA protein |
increases expression
|
protein |
14757314
|
D020148 | 2993 |
GYPA
CD235a GPA GPErik GPSAT HGpMiV HGpMiXI HGpSta(C) MN MNS PAS-2 |
glycophorin A (MNS blood group) | tellimagrandin I inhibits the reaction [Butyric Acid results in increased expression of GYPA protein] |
decreases reaction
/ increases expression |
protein |
14757314
|
D020148 | 10013 |
HDAC6
CPBHM HD6 |
histone deacetylase 6 (EC:3.5.1.98) | Butyric Acid promotes the reaction [SRSF2 protein binds to HDAC6 protein] |
affects binding
/ increases reaction |
protein |
21555914
|
D020148 | 10013 |
HDAC6
CPBHM HD6 |
histone deacetylase 6 (EC:3.5.1.98) | HDAC6 protein promotes the reaction [Butyric Acid results in increased expression of SRSF2 protein] |
increases expression
/ increases reaction |
protein |
21555914
|
D020148 | 8290 |
HIST3H3
H3.4 H3/g H3FT H3t |
histone cluster 3, H3 | Butyric Acid results in increased acetylation of HIST3H3 protein |
increases acetylation
|
protein |
14576182
|
D020148 | 121504 |
HIST4H4
H4/p |
histone cluster 4, H4 | Butyric Acid results in increased acetylation of HIST4H4 protein |
increases acetylation
|
protein |
15103026
|
D020148 | 3145 |
HMBS
PBG-D PBGD PORC UPS |
hydroxymethylbilane synthase (EC:2.5.1.61) | Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 3145 |
HMBS
PBG-D PBGD PORC UPS |
hydroxymethylbilane synthase (EC:2.5.1.61) | Butyric Acid results in increased expression of HMBS mRNA |
increases expression
|
mRNA |
10656287
14757314 |
D020148 | 3145 |
HMBS
PBG-D PBGD PORC UPS |
hydroxymethylbilane synthase (EC:2.5.1.61) | chebulinic acid inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
decreases reaction
/ increases expression |
mRNA |
14769215
|
D020148 | 3145 |
HMBS
PBG-D PBGD PORC UPS |
hydroxymethylbilane synthase (EC:2.5.1.61) | pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 3145 |
HMBS
PBG-D PBGD PORC UPS |
hydroxymethylbilane synthase (EC:2.5.1.61) | Quercetin inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 3145 |
HMBS
PBG-D PBGD PORC UPS |
hydroxymethylbilane synthase (EC:2.5.1.61) | tellimagrandin I inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
decreases reaction
/ increases expression |
mRNA |
14757314
|
D020148 | 3606 |
IL18
IGIF IL-18 IL-1g IL1F4 |
interleukin 18 (interferon-gamma-inducing factor) | Butyric Acid results in increased expression of IL18 mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Butyric Acid results in increased expression of IL6 mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | [Butyric Acid co-treated with Glucans] results in increased secretion of IL8 protein |
affects cotreatment
/ increases secretion |
protein |
15196572
|
D020148 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | [Butyric Acid co-treated with Zymosan] results in increased secretion of IL8 protein |
affects cotreatment
/ increases secretion |
protein |
15196572
|
D020148 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Butyric Acid results in increased expression of IL8 mRNA |
increases expression
|
mRNA |
15196572
17928716 |
D020148 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Butyric Acid results in increased secretion of IL8 protein |
increases secretion
|
protein |
15196572
|
D020148 | 3725 |
JUN
AP-1 AP1 c-Jun |
jun proto-oncogene | Butyric Acid results in decreased expression of JUN mRNA |
decreases expression
|
mRNA |
9007151
|
D020148 | 10524 |
KAT5
ESA1 HTATIP HTATIP1 PLIP TIP TIP60 ZC2HC5 cPLA2 |
K(lysine) acetyltransferase 5 (EC:2.3.1.48) | Butyric Acid promotes the reaction [KAT5 protein results in increased acetylation of SRSF2 protein] |
increases acetylation
/ increases reaction |
protein |
21555914
|
D020148 | 10524 |
KAT5
ESA1 HTATIP HTATIP1 PLIP TIP TIP60 ZC2HC5 cPLA2 |
K(lysine) acetyltransferase 5 (EC:2.3.1.48) | Butyric Acid promotes the reaction [SRSF2 protein binds to KAT5 protein] |
affects binding
/ increases reaction |
protein |
21555914
|
D020148 | 10524 |
KAT5
ESA1 HTATIP HTATIP1 PLIP TIP TIP60 ZC2HC5 cPLA2 |
K(lysine) acetyltransferase 5 (EC:2.3.1.48) | Butyric Acid results in increased expression of KAT5 mRNA |
increases expression
|
mRNA |
21555914
|
D020148 | 10524 |
KAT5
ESA1 HTATIP HTATIP1 PLIP TIP TIP60 ZC2HC5 cPLA2 |
K(lysine) acetyltransferase 5 (EC:2.3.1.48) | Butyric Acid results in increased expression of KAT5 protein |
increases expression
|
protein |
21555914
|
D020148 | 10524 |
KAT5
ESA1 HTATIP HTATIP1 PLIP TIP TIP60 ZC2HC5 cPLA2 |
K(lysine) acetyltransferase 5 (EC:2.3.1.48) | KAT5 protein promotes the reaction [Butyric Acid results in increased expression of SRSF2 protein] |
increases expression
/ increases reaction |
protein |
21555914
|
D020148 | 4254 |
KITLG
FPH2 KL-1 Kitl MGF SCF SF SHEP7 |
KIT ligand | Butyric Acid results in increased expression of KITLG mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 4609 |
MYC
MRTL MYCC bHLHe39 c-Myc |
v-myc avian myelocytomatosis viral oncogene homolog | Butyric Acid results in decreased expression of MYC mRNA |
decreases expression
|
mRNA |
9007151
|
D020148 | 4778 |
NFE2
NF-E2 p45 |
nuclear factor, erythroid 2 | Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 4778 |
NFE2
NF-E2 p45 |
nuclear factor, erythroid 2 | Butyric Acid results in increased expression of NFE2 mRNA |
increases expression
|
mRNA |
10656287
14757314 |
D020148 | 4778 |
NFE2
NF-E2 p45 |
nuclear factor, erythroid 2 | chebulinic acid inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
14769215
|
D020148 | 4778 |
NFE2
NF-E2 p45 |
nuclear factor, erythroid 2 | pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 4778 |
NFE2
NF-E2 p45 |
nuclear factor, erythroid 2 | Quercetin inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10656287
|
D020148 | 4778 |
NFE2
NF-E2 p45 |
nuclear factor, erythroid 2 | tellimagrandin I inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
14757314
|
D020148 | 11315 |
PARK7
DJ-1 DJ1 |
parkinson protein 7 | Butyric Acid results in increased expression of PARK7 mRNA |
increases expression
|
mRNA |
21372141
|
D020148 | 11315 |
PARK7
DJ-1 DJ1 |
parkinson protein 7 | Butyric Acid results in increased expression of PARK7 protein |
increases expression
|
protein |
21372141
|
D020148 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Butyric Acid results in increased expression of PPARG mRNA |
increases expression
|
mRNA |
10833422
|
D020148 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Butyric Acid results in increased expression of PPARG protein |
increases expression
|
protein |
10833422
|
D020148 | 5553 |
PRG2
BMPG MBP MBP1 |
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | Butyric Acid results in increased expression of PRG2 protein |
increases expression
|
protein |
14769150
|
D020148 | 5742 |
PTGS1
COX1 COX3 PCOX1 PES-1 PGG/HS PGHS-1 PGHS1 PHS1 PTGHS |
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Butyric Acid results in increased expression of PTGS1 mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Butyric Acid results in increased expression of PTGS2 mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 6647 |
SOD1
ALS ALS1 IPOA SOD hSod1 homodimer |
superoxide dismutase 1, soluble (EC:1.15.1.1) | Butyric Acid affects the activity of SOD1 protein |
affects activity
|
protein |
10656287
|
D020148 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | Butyric Acid results in decreased activity of SOD2 protein |
decreases activity
|
protein |
10656287
|
D020148 | 6732 |
SRPK1
SFRSK1 |
SRSF protein kinase 1 (EC:2.7.11.1) | Butyric Acid affects the localization of SRPK1 protein |
affects localization
|
protein |
21555914
|
D020148 | 6733 |
SRPK2
SFRSK2 |
SRSF protein kinase 2 (EC:2.7.11.1) | Butyric Acid affects the localization of SRPK2 protein |
affects localization
|
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | Butyric Acid promotes the reaction [KAT5 protein results in increased acetylation of SRSF2 protein] |
increases acetylation
/ increases reaction |
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | Butyric Acid promotes the reaction [SRSF2 protein binds to HDAC6 protein] |
affects binding
/ increases reaction |
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | Butyric Acid promotes the reaction [SRSF2 protein binds to KAT5 protein] |
affects binding
/ increases reaction |
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | Butyric Acid results in decreased phosphorylation of SRSF2 protein |
decreases phosphorylation
|
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | Butyric Acid results in increased expression of SRSF2 protein |
increases expression
|
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | [Butyric Acid results in increased expression of SRSF2 protein] which results in increased expression of CDKN1A mRNA |
increases expression
|
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | [Butyric Acid results in increased expression of SRSF2 protein] which results in increased expression of CDKN1A protein |
increases expression
|
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | HDAC6 protein promotes the reaction [Butyric Acid results in increased expression of SRSF2 protein] |
increases expression
/ increases reaction |
protein |
21555914
|
D020148 | 6427 |
SRSF2
PR264 SC-35 SC35 SFRS2 SFRS2A SRp30b |
serine/arginine-rich splicing factor 2 | KAT5 protein promotes the reaction [Butyric Acid results in increased expression of SRSF2 protein] |
increases expression
/ increases reaction |
protein |
21555914
|
D020148 | 7040 |
TGFB1
CED DPD1 LAP TGFB TGFbeta |
transforming growth factor, beta 1 | Butyric Acid results in increased expression of TGFB1 mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 7043 |
TGFB3
ARVD ARVD1 TGF-beta3 |
transforming growth factor, beta 3 | Butyric Acid results in increased expression of TGFB3 mRNA |
increases expression
|
mRNA |
17928716
|
D020148 | 7096 |
TLR1
CD281 TIL TIL._LPRS5 rsc786 |
toll-like receptor 1 | Butyric Acid results in increased expression of TLR1 mRNA |
increases expression
|
mRNA |
15196572
|
D020148 | 10333 |
TLR6
CD286 |
toll-like receptor 6 | Butyric Acid results in increased expression of TLR6 mRNA |
increases expression
|
mRNA |
15196572
|
D020148 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butyric Acid results in increased expression of TNF mRNA |
increases expression
|
mRNA |
17928716
|
MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
---|---|---|---|---|---|
D000230 | D020148 | Adenocarcinoma |
therapeutic
|
8298162
|
|
D001008 | D020148 | Anxiety Disorders |
marker/mechanism
|
12431849
|
|
D008175 | D020148 | Lung Neoplasms |
therapeutic
|
8298162
|
|
D009139 | D020148 | Musculoskeletal Abnormalities |
marker/mechanism
|
17517827
|
|
D012021 | D020148 | Reflex, Abnormal |
marker/mechanism
|
12915255
|