KCF-S cluster No. 3692 (3 metabolites)

Corresponding Phytochemical cluster No. 68

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	3
asterids	2
Liliopsida	1
eudicotyledons	1

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Cumulative family count

class name	count
Brassicaceae	2
Caprifoliaceae	1
Sapotaceae	1
Vitaceae	1
Arecaceae	1
Ganodermataceae	1
Caryophyllaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Saturated fatty acids	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Saturated fatty acids	C00246	C00001180
Saturated fatty acids	C01585	C00001218

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001180	Butyric acid	CHEMBL14227	D020148	12 / 3 / 2	40 / 5
C00001208	Valeric acid	CHEMBL268736	C038780	1 / 7 / 3
C00001218	Caproic acid / Hexanoic acid / 1-Hexanoic acid / n-Hexanoic acid	CHEMBL14184	C037652	5 / 0 / 0

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00001180 C00001218	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00001180 C00001218	0 / 0
O15379	Histone deacetylase 3	Hydrolase	C00001180	0 / 0
Q92769	Histone deacetylase 2	Hydrolase	C00001180	0 / 0
Q9UQL6	Histone deacetylase 5	Hydrolase	C00001180	0 / 0
P15121	Aldose reductase	Enzyme	C00001218	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001208	7 / 3
Q9UGP5	DNA polymerase lambda	Enzyme	C00001218	0 / 0
Q9BY41	Histone deacetylase 8	Hydrolase	C00001180	2 / 0
Q7Z4W1	L-xylulose reductase	Enzyme	C00001180	0 / 1
Q13547	Histone deacetylase 1	Hydrolase	C00001180	0 / 0
P56524	Histone deacetylase 4	Hydrolase	C00001180	1 / 1
Q8WUI4	Histone deacetylase 7	Hydrolase	C00001180	0 / 0
Q9UBN7	Histone deacetylase 6	Hydrolase	C00001180	0 / 0
Q9UKV0	Histone deacetylase 9	Hydrolase	C00001180	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001218	0 / 0

40 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001180
567	B2M	beta-2-microglobulin	C00001180
581	BAX, BCL2L4	BCL2-associated X protein	C00001180
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00001180
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001180
1081	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA	glycoprotein hormones, alpha polypeptide	C00001180
64581	CLEC7A, BGR, CANDF4, CLECSF12, DECTIN1	C-type lectin domain family 7, member A	C00001180
2002	ELK1	ELK1, member of ETS oncogene family	C00001180
8288	EPX, EPO, EPP, EPX-PEN	eosinophil peroxidase (EC:1.11.1.7)	C00001180
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00001180
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00001180
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00001180
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00001180
10013	HDAC6, CPBHM, HD6	histone deacetylase 6 (EC:3.5.1.98)	C00001180
8290	HIST3H3, H3.4, H3/g, H3FT, H3t	histone cluster 3, H3	C00001180
121504	HIST4H4, H4/p	histone cluster 4, H4	C00001180
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00001180
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00001180
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001180
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001180
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00001180
10524	KAT5, ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2	K(lysine) acetyltransferase 5 (EC:2.3.1.48)	C00001180
4254	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7	KIT ligand	C00001180
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001180
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00001180
11315	PARK7, DJ-1, DJ1	parkinson protein 7	C00001180
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00001180
5553	PRG2, BMPG, MBP, MBP1	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	C00001180
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001180
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001180
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001180
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00001180
6732	SRPK1, SFRSK1	SRSF protein kinase 1 (EC:2.7.11.1)	C00001180
6733	SRPK2, SFRSK2	SRSF protein kinase 2 (EC:2.7.11.1)	C00001180
6427	SRSF2, PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b	serine/arginine-rich splicing factor 2	C00001180
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00001180
7043	TGFB3, ARVD, ARVD1, TGF-beta3	transforming growth factor, beta 3	C00001180
7096	TLR1, CD281, TIL, TIL._LPRS5, rsc786	toll-like receptor 1	C00001180
10333	TLR6, CD286	toll-like receptor 6	C00001180
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001180

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions