KCF-S cluster No. 5377 (2 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 3 |
| asterids | 3 |
| eudicotyledons | 2 |
| Liliopsida | 1 |
Cumulative family count
| class name | count |
|---|---|
| Fabaceae | 2 |
| Asteraceae | 1 |
| Amaranthaceae | 1 |
| Poaceae | 1 |
| Apiaceae | 1 |
| Brassicaceae | 1 |
| Enterobacteriaceae | 1 |
| Gunneraceae | 1 |
| Sapotaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (2)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001193
|
Malonic acid
|
CHEMBL7942
|
C030290
|
6 / 1 / 5 | 1 / 2 |
|
|
C00001205
|
Succinic acid
|
CHEMBL576
|
D019802
|
6 / 13 / 17 | 1 / 3 |
|
Human Protein / Gene in interactions
11 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16798 | NADP-dependent malic enzyme, mitochondrial | Enzyme | C00001193 C00001205 | 0 / 0 |
| Q8TCC7 | Solute carrier family 22 member 8 | Antiporter | C00001205 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001205 | 11 / 10 |
| P14920 | D-amino-acid oxidase | Enzyme | C00001193 | 0 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00001205 | 1 / 1 |
| Q99489 | D-aspartate oxidase | Enzyme | C00001193 | 0 / 0 |
| Q9GZT4 | Serine racemase | Enzyme | C00001193 | 0 / 0 |
| P00338 | L-lactate dehydrogenase A chain | Enzyme | C00001193 | 1 / 5 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00001193 | 0 / 0 |
| Q7Z4W1 | L-xylulose reductase | Enzyme | C00001205 | 0 / 1 |
| Q00987 | E3 ubiquitin-protein ligase Mdm2 | Other nuclear protein | C00001205 | 1 / 5 |
2 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00001193
|
| 64849 | SLC13A3, NADC3, SDCT2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
C00001205
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (14)
| OMIM | preferred title | UniProt |
|---|---|---|
| #614401 | Accelerated tumor formation, susceptibility to; actfs |
Q00987
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #612933 | Glycogen storage disease xi; gsd11 |
P00338
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
KEGG DISEASE (22)
| KEGG | name | UniProt |
|---|---|---|
| H00069 | Glycogen storage diseases (GSD) |
P00338
(related)
|
| H00010 | Multiple myeloma |
P00338
(marker)
|
| H00023 | Testicular cancer |
P00338
(marker)
|
| H00035 | Ewing's sarcoma |
P00338
(marker)
|
| H00043 | Neuroblastoma |
P00338
(marker)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00025 | Penile cancer |
Q00987
(related)
|
| H00028 | Choriocarcinoma |
Q00987
(related)
|
| H00036 | Osteosarcoma |
Q00987
(related)
|
| H00037 | Alveolar rhabdomyosarcoma |
Q00987
(related)
|
| H00042 | Glioma |
Q00987
(related)
|
| H01065 | Pentosuria |
Q7Z4W1
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|