PCIDB

KNApSAcK Metabolite C00001151

Metabolite

KNApSAcK Entry

id C00001151
Name Sucrose / (+)-Sucrose
CAS RN 57-50-1
Standard InChI InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4?,5-,6-,7?,8+,9?,10-,11-,12+/m1/s1
Standard InChI (Main Layer) InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2

Cluster

Phytochemical cluster
KCF-S cluster No. 3949

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL253582 CHEMBL1976550

KEGG

By LinkDB C00089

CTD

By CAS RN D013395

Species

Summary

Plant class

class name count
asterids 11
rosids 10
Liliopsida 3
eudicotyledons 2
Euphyllophyta 1
Embryophyta 1

Family (Top 10)

family name count
Fabaceae 5
Poaceae 3
Solanaceae 3
Asteraceae 2
Brassicaceae 2
Apiaceae 2
Malvaceae 1
Cucurbitaceae 1
Amaranthaceae 1
Plantaginaceae 1

List (28)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acer saccharum 4024 Aceraceae rosids Viridiplantae
Ajuga reptans 38596 Lamiaceae asterids Viridiplantae
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Beta vulgaris 161934 Amaranthaceae eudicotyledons Viridiplantae
Brassica oleracea 3712 Brassicaceae rosids Viridiplantae
Caragana microphylla 220690 Fabaceae rosids Viridiplantae
Cucumis sativus 3659 Cucurbitaceae rosids Viridiplantae
Derris oblonga 53864 Fabaceae rosids Viridiplantae
Genista corsica 319660 Fabaceae rosids Viridiplantae
Glycine max 3847 Fabaceae rosids Viridiplantae
Gossypium hirsutum 3635 Malvaceae rosids Viridiplantae
Helianthus annuus 4232 Asteraceae asterids Viridiplantae
Lycopersicon esculentum 4081 Solanaceae asterids Viridiplantae
Marsdenia tomentosa 276779 Apocynaceae asterids Viridiplantae
Nicotiana sylvestris 4096 Solanaceae asterids Viridiplantae
Paeonia peregrina 40717 Paeoniaceae eudicotyledons Viridiplantae
Petroselinum crispum 4043 Apiaceae asterids Viridiplantae
Phaseolus vulgaris 3885 Fabaceae rosids Viridiplantae
Pimpinella anisum L. 271192 Apiaceae asterids Viridiplantae
Plantago lanceolata 39414 Plantaginaceae asterids Viridiplantae
Polytrichum commune 3213 Polytrichaceae Embryophyta Viridiplantae
Pteris multifida 170715 Pteridaceae Euphyllophyta Viridiplantae
Robinsonecio gerberifolius 98718 Asteraceae asterids Viridiplantae
Saccharum officinarum 4547 Poaceae Liliopsida Viridiplantae
Sebertia acuminata 280718 Sapotaceae asterids Viridiplantae
Solanum lycopersicum L. 4081 Solanaceae asterids Viridiplantae
Sorghum bicolor 4558 Poaceae Liliopsida Viridiplantae
Zea mays 4577 Poaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

1 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P02768 Serum albumin Secreted protein CHEMBL253582 CHEMBL702884 (1)
0 / 0

CTD interaction (5)

compound gene gene name gene description interaction interaction type form reference
pmid
D013395 3630 INS
IDDM2
ILPR
IRDN
MODY10
insulin Sucrose results in increased expression of INS protein increases expression
protein 1805284
D013395 55630 SLC39A4
AEZ
AWMS2
ZIP4
solute carrier family 39 (zinc transporter), member 4 Sucrose inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] decreases reaction
/ increases degradation
protein 17202136
D013395 80834 TAS1R2
GPR71
T1R2
TR2
taste receptor, type 1, member 2 Sucrose binds to and results in increased activity of TAS1R2 protein affects binding
/ increases activity
protein 20173092
D013395 80834 TAS1R2
GPR71
T1R2
TR2
taste receptor, type 1, member 2 Sucrose results in increased activity of [TAS1R2 protein binds to TAS1R3 protein] affects binding
/ increases activity
protein 20173092
D013395 83756 TAS1R3
T1R3
taste receptor, type 1, member 3 Sucrose results in increased activity of [TAS1R2 protein binds to TAS1R3 protein] affects binding
/ increases activity
protein 20173092

Related Disease

Diseases related to CTD interactions

10 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D019969 D013395 Amphetamine-Related Disorders therapeutic
18495228
D018149 D013395 Glucose Intolerance marker/mechanism
18806091
D006461 D013395 Hemolysis therapeutic
14993803
D006946 D013395 Hyperinsulinism marker/mechanism
18806091
D006948 D013395 Hyperkinesis marker/mechanism
14596845
D006973 D013395 Hypertension marker/mechanism
18374418
D007333 D013395 Insulin Resistance marker/mechanism
18806091
D009401 D013395 Nephrosis marker/mechanism
18295066
C541083 D013395 Non-alcoholic Fatty Liver Disease marker/mechanism
23127599
D019966 D013395 Substance-Related Disorders marker/mechanism
15763572