Solanum lycopersicum L.

• Index
• Plant Species
• Metabolite list (15)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Solanum lycopersicum L.
Genus	Solanum
Family	Solanaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Solanum lycopersicum
Linked NCBI taxonomy ID	4081
Linked level	species

Family

Family in NCBI taxonomy	Solanaceae
ID	4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (15)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001140	Maltose	CHEMBL417016 CHEMBL469865 CHEMBL470274 CHEMBL1254686 CHEMBL1903530 CHEMBL1908365	D008320	6 / 0 / 1	2 / 0	No. 423	No. 73
C00001152	Trehalose		D014199			No. 423	No. 73
C00001434	Tryptamine / beta-(3-Indolyl)ethylamine	CHEMBL6640	C030820	20 / 5 / 7	6 / 2	No. 710	No. 4
C00001164	Myoinositol / myo-Inositol	CHEMBL278373 CHEMBL468154 CHEMBL1222251 CHEMBL1231671 CHEMBL1950780		8 / 17 / 18		No. 795
C00001435	Tyramine	CHEMBL11608	D014439	23 / 11 / 6	6 / 9	No. 936	No. 6
C00001408	Dopamine	CHEMBL59	D004298	69 / 40 / 56	51 / 52	No. 1114	No. 6
C00034198	Ribose / D-Ribose		D012266		1 / 0	No. 1384
C00019681	Galactose / D-Galactose / D-(+)-Galactose	CHEMBL1206211				No. 1384
C00035100	Fucose / L-(-)-Fucose					No. 1384
C00033848	Fructose / D-Fructose / D-(-)-Fructose	CHEMBL23894 CHEMBL1869413		9 / 4 / 3		No. 1614
C00001161	Erythritol / meso-Erythritol	CHEMBL349605 CHEMBL402812	D004896	3 / 5 / 5		No. 2923
C00001428	Putrescine	CHEMBL46257	D011700	9 / 5 / 4	3 / 4	No. 3767
C00001361	Glycine	CHEMBL773		95 / 37 / 32		No. 3932
C00001151	Sucrose / (+)-Sucrose	CHEMBL253582 CHEMBL1976550	D013395	1 / 0 / 0	4 / 10	No. 3949
C00001431	Spermidine	CHEMBL19612	D013095	26 / 10 / 12	5 / 5	No. 5867

Human Protein / Gene in interactions

181 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001361 C00001408 C00001428 C00001431 C00001434 C00001435	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001361 C00001408 C00001428 C00001431 C00001434 C00001435	0 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001361 C00001408 C00001428 C00001431 C00001434 C00001435	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001361 C00001408 C00001428 C00001431 C00001434 C00001435	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001361 C00001408 C00001428 C00001431 C00001434 C00001435	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00001161 C00001361 C00001408 C00001431	1 / 2
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001361 C00001408 C00001434 C00001435	0 / 0
O75496	Geminin	Unclassified protein	C00001164 C00001434 C00001435 C00033848	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001428 C00001435 C00033848	2 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00001161 C00001408 C00001431	0 / 1
P21917	D(4) dopamine receptor	Dopamine receptor	C00001361 C00001408 C00001435	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001408 C00001435 C00033848	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001408 C00001431 C00001435	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00001361 C00001408 C00001435	2 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00001361 C00001408	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00001361 C00001408	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00001434 C00033848	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001164 C00001408	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00001361 C00001408	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00001408 C00001431	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00001408 C00001431	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00001408 C00001431	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00001408 C00001431	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00001408 C00001431	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00001428 C00001434	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001361 C00001434	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001361 C00001434	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00001361 C00001408	1 / 0
P22748	Carbonic anhydrase 4	Lyase	C00001408 C00001431	1 / 1
O15245	Solute carrier family 22 member 1	Drug uniporter	C00001408 C00001435	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001408 C00033848	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001408 C00001435	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00001361 C00001408	0 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00001361 C00001434	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001361 C00001408	2 / 0
P40225	Thrombopoietin	Unclassified protein	C00001408 C00001431	1 / 1
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00001361 C00001408	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00001361 C00001435	1 / 1
P14679	Tyrosinase	Oxidoreductase	C00001408 C00001435	4 / 2
P00915	Carbonic anhydrase 1	Lyase	C00001408 C00001431	0 / 0
P46098	5-hydroxytryptamine receptor 3A	NS	C00001361 C00001435	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00001361 C00001408	1 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00001361 C00001408	1 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00001361 C00001408	0 / 0
Q9H015	Solute carrier family 22 member 4	Unclassified protein	C00001428 C00001431	1 / 1
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00001361 C00001408	0 / 0
P10323	Acrosin	S1A	C00001164 C00033848	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001408 C00033848	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00001361 C00001434	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00001361 C00001408	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00001408 C00001431	1 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00001408 C00001435	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001408 C00001431	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00001408 C00001431	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00001408 C00001431	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001431 C00001434	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001361	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00001361	1 / 8
P11473	Vitamin D3 receptor	NR1I1	C00033848	2 / 3
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001434	1 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00001361	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00001361	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00001361	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00001361	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00001361	0 / 0
P09382	Galectin-1	Other cytosolic protein	C00001140	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00001361	0 / 0
P05164	Myeloperoxidase	Enzyme	C00001434	1 / 2
P43235	Cathepsin K	C1A	C00001434	1 / 2
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00001361	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001431	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00001361	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00001361	1 / 0
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00001408	0 / 0
O95622	Adenylate cyclase type 5	Enzyme	C00001408	1 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00001361	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00001361	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00001408	0 / 0
P02768	Serum albumin	Secreted protein	C00001151	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001431	0 / 0
O00214	Galectin-8	Unclassified protein	C00001140	0 / 0
P16278	Beta-galactosidase	Enzyme	C00001164	4 / 6
P50225	Sulfotransferase 1A1	Enzyme	C00001408	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00001408	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00001361	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00001361	0 / 0
P21918	D(1B) dopamine receptor	Dopamine receptor	C00001408	1 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00001361	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00001361	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00001361	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00001361	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00001361	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00001361	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00001361	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00001361	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00001361	1 / 0
P28222	5-hydroxytryptamine receptor 1B	Serotonin receptor	C00001434	0 / 0
Q6QHF9	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	Enzyme	C00001431	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00001361	0 / 0
P08311	Cathepsin G	S1A	C00001361	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00001361	1 / 0
P03956	Interstitial collagenase	M10A	C00001361	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00001361	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001435	0 / 0
P50224	Sulfotransferase 1A3/1A4	Enzyme	C00001408	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00001361	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00001361	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00001361	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00001361	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00001361	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00001431	3 / 2
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00001361	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00001361	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00001361	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00001361	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00001361	3 / 0
P37840	Alpha-synuclein	Unclassified protein	C00001161	4 / 2
P36544	Neuronal acetylcholine receptor subunit alpha-7	CHRN alpha	C00001361	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00001164	1 / 1
P48039	Melatonin receptor type 1A	Melatonin receptor	C00001408	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00001361	1 / 0
P23415	Glycine receptor subunit alpha-1	GLR alpha	C00001361	1 / 1
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00001361	2 / 1
P56817	Beta-secretase 1	A1A	C00001435	0 / 0
O43704	Sulfotransferase family cytosolic 1B member 1	Enzyme	C00001408	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00001164	11 / 10
Q16853	Membrane primary amine oxidase	Enzyme	C00001408	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001408	3 / 3
P47929	Galectin-7	Unclassified protein	C00001140	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00001361	0 / 0
P03372	Estrogen receptor	NR3A1	C00001361	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00033848	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00001361	1 / 0
P14780	Matrix metalloproteinase-9	M10A	C00001361	2 / 2
P27361	Mitogen-activated protein kinase 3	Erk	C00001361	0 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00001408	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00001361	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00001361	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00001361	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00001361	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00001361	0 / 0
P29466	Caspase-1	C14	C00001361	0 / 0
P49286	Melatonin receptor type 1B	Melatonin receptor	C00001408	0 / 1
P46059	Solute carrier family 15 member 1	Dipeptide	C00001361	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00001361	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00001361	0 / 0
Q96RJ0	Trace amine-associated receptor 1	Trace amine receptor	C00001435	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00001361	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001408	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00001408	5 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00001408	4 / 3
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00001408	0 / 0
Q7Z2H8	Proton-coupled amino acid transporter 1	Unclassified protein	C00001361	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001434	0 / 0
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00001164	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00001361	0 / 0
P08246	Neutrophil elastase	S1A	C00001361	2 / 1
P28221	5-hydroxytryptamine receptor 1D	Serotonin receptor	C00001434	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00001361	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00001361	2 / 2
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00001361	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00001361	0 / 3
P06239	Tyrosine-protein kinase Lck	Src	C00001361	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00001361	0 / 0
Q6P4F1	Alpha-(1,3)-fucosyltransferase 10	Enzyme	C00001140	0 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00001435	0 / 0
P17931	Galectin-3	Other cytosolic protein	C00001140	0 / 1
Q99700	Ataxin-2	Unclassified protein	C00001408	1 / 1
O00182	Galectin-9	Unclassified protein	C00001140	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00001408	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00001408	0 / 0
O15244	Solute carrier family 22 member 2	Drug uniporter	C00001408	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00001408	7 / 37
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001408	1 / 1
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00001408	3 / 0
O75751	Solute carrier family 22 member 3	Unclassified protein	C00001435	0 / 0
Q05BR4	SLC16A10 protein	Unclassified protein	C00001361	0 / 0
P35368	Alpha-1B adrenergic receptor	Adrenergic receptor	C00001408	0 / 0
P35348	Alpha-1A adrenergic receptor	Adrenergic receptor	C00001408	0 / 0
P17707	S-adenosylmethionine decarboxylase proenzyme	Enzyme	C00001428	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001164	1 / 1

65 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
6530	SLC6A2, NAT1, NET, NET1, SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 2	C00001408 C00001434 C00001435
134864	TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1	trace amine associated receptor 1	C00001408 C00001434 C00001435
6531	SLC6A3, DAT, DAT1, PKDYS	solute carrier family 6 (neurotransmitter transporter), member 3	C00001408 C00001434 C00001435
6532	SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT	solute carrier family 6 (neurotransmitter transporter), member 4	C00001408 C00001434 C00001435
153	ADRB1, ADRB1R, B1AR, BETA1AR, RHR	adrenoceptor beta 1	C00001428 C00001431
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001428 C00001431
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00001408 C00001435
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001151 C00001408
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001408 C00001431
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00001408
664	BNIP3, NIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	C00001408
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00001408
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00001408
847	CAT	catalase (EC:1.11.1.6)	C00001408
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00001408
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001408
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00001408
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00001408
1812	DRD1, DADR, DRD1A	dopamine receptor D1	C00001408
1813	DRD2, D2DR, D2R	dopamine receptor D2	C00001408
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00001408
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00001408
2668	GDNF, ATF1, ATF2, HFB1-GDNF, HSCR3	glial cell derived neurotrophic factor	C00001408
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00001408
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00001408
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00001408
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00001408
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00001408
3359	HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	C00001408
9177	HTR3B, 5-HT3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	C00001408
581	BAX, BCL2L4	BCL2-associated X protein	C00001408
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00001408
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00001408
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00001408
4137	MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU	microtubule-associated protein tau	C00001408
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00001408
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00001408
5071	PARK2, AR-JP, LPRS2, PDJ, PRKN	parkin RBR E3 ubiquitin protein ligase	C00001408
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001408
5617	PRL	prolactin	C00001408
5998	RGS3, C2PA, RGP3	regulator of G-protein signaling 3	C00001408
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00001408
6343	SCT	secretin	C00001408
6570	SLC18A1, CGAT, VAT1, VMAT1	solute carrier family 18 (vesicular monoamine transporter), member 1	C00001408
6571	SLC18A2, SVAT, SVMT, VAT2, VMAT2	solute carrier family 18 (vesicular monoamine transporter), member 2	C00001408
85413	SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1	solute carrier family 22 (organic cation/carnitine transporter), member 16	C00001408
9016	SLC25A14, BMCP1, UCP5	solute carrier family 25 (mitochondrial carrier, brain), member 14	C00001408
6622	SNCA, NACP, PARK1, PARK4, PD1	synuclein, alpha (non A4 component of amyloid precursor)	C00001408
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001408
183	AGT, ANHU, SERPINA8	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	C00001408
7054	TH, DYT14, DYT5b, TYH	tyrosine hydroxylase (EC:1.14.16.2)	C00001408
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001408
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00001408
6514	SLC2A2, GLUT2	solute carrier family 2 (facilitated glucose transporter), member 2	C00001140
6515	SLC2A3, GLUT3	solute carrier family 2 (facilitated glucose transporter), member 3	C00001140
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00001434
3356	HTR2A, 5-HT2A, HTR2	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	C00001434
26	AOC1, ABP, ABP1, DAO, DAO1, KAO	amine oxidase, copper containing 1 (EC:1.4.3.22)	C00001428
567	B2M	beta-2-microglobulin	C00034198
486	FXYD2, ATP1G1, HOMG2	FXYD domain containing ion transport regulator 2	C00001431
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00001431
55630	SLC39A4, AEZ, AWMS2, ZIP4	solute carrier family 39 (zinc transporter), member 4	C00001151
80834	TAS1R2, GPR71, T1R2, TR2	taste receptor, type 1, member 2	C00001151
83756	TAS1R3, T1R3	taste receptor, type 1, member 3	C00001151
4128	MAOA, MAO-A	monoamine oxidase A (EC:1.4.3.4)	C00001435

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions