Plant Species


Cumulative plant class count

class name count
rosids 7
eudicotyledons 4
asterids 3
Liliopsida 1

Cumulative family count

class name count
Fabaceae 4
Brassicaceae 3
Solanaceae 3
Montiaceae 3
Crassulaceae 1
Enterobacteriaceae 1
Poaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001403 External link 512 Cadaverine
CHEMBL119296
D002103
12 / 3 / 5
C00001428 External link 512 Putrescine
CHEMBL46257
D011700
9 / 5 / 4 3 / 4
C00007404 External link 512 1,3-Diaminopropane
CHEMBL174324
C009475
6 / 0

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001428 1 / 0
P17707 S-adenosylmethionine decarboxylase proenzyme Enzyme C00001428 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001428 2 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00001403 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00001403 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00001403 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00001403 1 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001428 0 / 1
P23280 Carbonic anhydrase 6 Lyase C00001403 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00001403 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00001403 1 / 2
P00915 Carbonic anhydrase 1 Lyase C00001403 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001428 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00001403 0 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00001428 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001428 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001428 0 / 1
P07451 Carbonic anhydrase 3 Lyase C00001403 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001403 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001403 0 / 0
Q9H015 Solute carrier family 22 member 4 Unclassified protein C00001428 1 / 1

9 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00007404
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00007404
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00007404
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00007404
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00007404
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00007404
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00001428
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00001428
26 AOC1, ABP, ABP1, DAO, DAO1, KAO amine oxidase, copper containing 1 (EC:1.4.3.22) C00001428

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#143860 Hyperchlorhidrosis, isolated O43570
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748
#180300 Rheumatoid arthritis; ra Q9H015
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798

KEGG DISEASE (9)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00286 Crohn's disease Q9H015 (related)

Diseases related to CTD interactions

4 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006332 Cardiomegaly C00001428
D056486 Drug-Induced Liver Injury C00001428
D006973 Hypertension C00001428
D011230 Precancerous Conditions C00001428