class name | count |
---|---|
rosids | 7 |
eudicotyledons | 4 |
asterids | 3 |
Liliopsida | 1 |
class name | count |
---|---|
Fabaceae | 4 |
Brassicaceae | 3 |
Solanaceae | 3 |
Montiaceae | 3 |
Crassulaceae | 1 |
Enterobacteriaceae | 1 |
Poaceae | 1 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00001403
![]() |
Cadaverine
|
CHEMBL119296
|
D002103
|
12 / 3 / 5 |
![]() |
|
C00001428
![]() |
Putrescine
|
CHEMBL46257
|
D011700
|
9 / 5 / 4 | 3 / 4 |
![]() |
C00007404
![]() |
1,3-Diaminopropane
|
CHEMBL174324
|
C009475
|
6 / 0 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001428 | 1 / 0 |
P17707 | S-adenosylmethionine decarboxylase proenzyme | Enzyme | C00001428 | 0 / 0 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001428 | 2 / 0 |
Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00001403 | 0 / 0 |
P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00001403 | 0 / 0 |
P43166 | Carbonic anhydrase 7 | Lyase | C00001403 | 0 / 0 |
P00918 | Carbonic anhydrase 2 | Lyase | C00001403 | 1 / 2 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001428 | 0 / 1 |
P23280 | Carbonic anhydrase 6 | Lyase | C00001403 | 0 / 0 |
Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00001403 | 0 / 0 |
O43570 | Carbonic anhydrase 12 | Lyase | C00001403 | 1 / 2 |
P00915 | Carbonic anhydrase 1 | Lyase | C00001403 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001428 | 0 / 0 |
Q16790 | Carbonic anhydrase 9 | Lyase | C00001403 | 0 / 1 |
P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001428 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001428 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001428 | 0 / 1 |
P07451 | Carbonic anhydrase 3 | Lyase | C00001403 | 0 / 0 |
P22748 | Carbonic anhydrase 4 | Lyase | C00001403 | 1 / 1 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00001403 | 0 / 0 |
Q9H015 | Solute carrier family 22 member 4 | Unclassified protein | C00001428 | 1 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00007404
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00007404
|
1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00007404
|
54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00007404
|
6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00007404
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00007404
|
153 | ADRB1, ADRB1R, B1AR, BETA1AR, RHR | adrenoceptor beta 1 |
C00001428
|
154 | ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR | adrenoceptor beta 2, surface |
C00001428
|
26 | AOC1, ABP, ABP1, DAO, DAO1, KAO | amine oxidase, copper containing 1 (EC:1.4.3.22) |
C00001428
|
OMIM | preferred title | UniProt |
---|---|---|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#143860 | Hyperchlorhidrosis, isolated |
O43570
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
#180300 | Rheumatoid arthritis; ra |
Q9H015
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
KEGG | name | UniProt |
---|---|---|
H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00286 | Crohn's disease |
Q9H015
(related)
|