PCIDB

KNApSAcK Metabolite C00007404

Metabolite

KNApSAcK Entry

id C00007404
Name 1,3-Diaminopropane
CAS RN 109-76-2
Standard InChI InChI=1S/C3H10N2/c4-2-1-3-5/h1-5H2
Standard InChI (Main Layer) InChI=1S/C3H10N2/c4-2-1-3-5/h1-5H2

Cluster

Phytochemical cluster
KCF-S cluster No. 3767

Link

ChEMBL

By standard InChI CHEMBL174324
By standard InChI Main Layer CHEMBL174324

KEGG

By LinkDB C00986

CTD

By CAS RN C009475

Human Protein / Gene in interaction

CTD interaction (8)

compound gene gene name gene description interaction interaction type form reference
pmid
C009475 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Copper binds to Isatin binds to trimethylenediamine] which results in increased cleavage of CASP3 protein affects binding
/ increases cleavage
protein 17327230
C009475 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) [Copper binds to Isatin binds to trimethylenediamine] which results in increased cleavage of CASP9 protein affects binding
/ increases cleavage
protein 17327230
C009475 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of CDKN1A protein affects binding
/ increases expression
protein 17327230
C009475 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Tretinoin inhibits the reaction [[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of CDKN1A protein] affects binding
/ decreases reaction
/ increases expression
protein 17327230
C009475 54205 CYCS
CYC
HCS
THC4
cytochrome c, somatic [Copper binds to Isatin binds to trimethylenediamine] which affects the localization of CYCS protein affects binding
/ affects localization
protein 17327230
C009475 6647 SOD1
ALS
ALS1
IPOA
SOD
hSod1
homodimer
superoxide dismutase 1, soluble (EC:1.15.1.1) SOD1 protein results in decreased susceptibility to [Copper binds to Isatin binds to trimethylenediamine] affects binding
/ decreases response to substance
protein 17327230
C009475 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 [Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein affects binding
/ increases expression
protein 17327230
C009475 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Tretinoin inhibits the reaction [[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein] affects binding
/ decreases reaction
/ increases expression
protein 17327230