PCIDB

Beta vulgaris

Species

KNApSAcK Entry

Organism name Beta vulgaris
Genus Beta
Family Chenopodiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Beta vulgaris
Linked NCBI taxonomy ID 161934
Linked level species

Family

Family in NCBI taxonomy Amaranthaceae
ID 3563

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (35)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00014091 External link 512 Vitexin 6''-O-malonyl 2''-O-xyloside
No. 1 No. 15
C00038590 External link 512 Betavulgaroside III
No. 9 No. 51
C00038591 External link 512 Betavulgaroside V
/ (+)-Betavulgaroside V
No. 9 No. 51
C00048504 External link 512 Pennogenin 3-O-beta-chacotrioside
/ (-)-Pennogenin 3-O-beta-chacotrioside
CHEMBL501681
No. 17 No. 11
C00048333 External link 512 Bethoside B
/ (-)-Bethoside B
No. 17 No. 11
C00048513 External link 512 Polygonatoside B3
/ (-)-Polygonatoside B3
CHEMBL478738
No. 17 No. 11
C00003585 External link 512 Protodioscin
/ 3beta,22alpha,26-Trihydroxyfurost-5-ene-3-O-beta-chacotrioside-26-O-beta-D-glucopyranoside
CHEMBL1163175
CHEMBL1981285
CHEMBL1995734
No. 21 No. 11
C00048332 External link 512 Bethoside A
/ (-)-Bethoside A
No. 21 No. 11
C00002509 External link 512 Betavulgarin
/ 2'-Hydroxy-5-methoxy-6,7-methylenedioxyisoflavone
No. 27 No. 15
C00009856 External link 512 Irisone B
/ 5,2'-Dihydroxy-6,7-methylenedioxyisoflavone
CHEMBL443974
C053588
No. 27 No. 15
C00002508 External link 512 Anhydroglycinol
/ 3,9-Dihydroxypterocarpene
No. 27 No. 15
C00003538 External link 512 Silphioside F
/ Calenduloside E
/ (+)-Silphioside F
/ (+)-Calenduloside E
/ Oleanoic acid 3-O-glucuronide
CHEMBL446866
CHEMBL1974914
No. 50 No. 51
C00003666 External link 512 Polypodine B
CHEMBL522181
CHEMBL502028
CHEMBL1567145
1 / 1 / 0 No. 58 No. 11
C00000942 External link 512 Betagarin
No. 77 No. 14
C00001263 External link 512 Octacosan-1-ol
CHEMBL1951714
C044309
No. 115
C00048334 External link 512 Bethoside C
/ (-)-Bethoside C
No. 182
C00001162 External link 512 Galactinol
No. 423 No. 73
C00001430 External link 512 Skatole
CHEMBL1329793
D012862
2 / 1 / 4 7 / 1 No. 710 No. 4
C00001606 External link 512 Prebetanin
No. 763 No. 71
C00001584 External link 512 Betanin
CHEMBL1172614
C020228
0 / 2 No. 763 No. 71
C00000096 External link 512 9-Ribosyl-trans-zeatin
/ Zeatin-9-beta-D-ribofuranoside
No. 989
C00001590 External link 512 Humilixanthin
No. 1220 No. 71
C00001607 External link 512 Vulgaxanthin I
C018416
No. 1220 No. 71
C00001608 External link 512 Vulgaxanthin-II
No. 1220 No. 71
C00002743 External link 512 Ferulic acid
/ 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid
CHEMBL32749
C004999
110 / 52 / 40 16 / 6 No. 1366 No. 6
C00001343 External link 512 L-Azetidine 2-carboxylic acid
CHEMBL33592
CHEMBL1165239
CHEMBL1599178
C089382
8 / 14 / 15 No. 1523 No. 1
C00002735 External link 512 Dihydrocaffeic acid
CHEMBL136927
C000995
1 / 2 / 0 1 / 1 No. 1584
C00001184 External link 512 Glutaric acid
CHEMBL1162495
C035736
3 / 0 / 0 2 / 0 No. 1853
C00001178 External link 512 Adipic acid
CHEMBL1157
C029900
4 / 14 / 11 1 / 0 No. 1853
C00000094 External link 512 2iP
/ N6-(delta2-Isopentenyl)adenine
CHEMBL476189
C001478
5 / 2 / 3 18 / 0 No. 2879
C00000113 External link 512 Indole-3-carboxylic acid
CHEMBL387527
C012382
1 / 3 / 4 No. 3632
C00001151 External link 512 Sucrose
/ (+)-Sucrose
CHEMBL253582
CHEMBL1976550
D013395
1 / 0 / 0 4 / 10 No. 3949
C00008598 External link 512 3,5-Dihydroxy-6,7-methylenedioxyflavanone
CHEMBL1802148
No. 4289
C00001193 External link 512 Malonic acid
CHEMBL7942
C030290
6 / 1 / 5 1 / 2 No. 5377
C00001582 External link 512 Betalamic acid
CHEMBL2062984
C000252
No. 7291 No. 71

Human Protein / Gene in interactions

130 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000094 C00001343 C00002743 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000094 C00001343 C00002743 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000094 C00001343 C00002743 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000094 C00001343 C00002743 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000094 C00001343 C00002743 0 / 0
O75496 Geminin Unclassified protein C00001430 C00002743 0 / 0
P02545 Prelamin-A/C Unclassified protein C00001178 C00001343 11 / 10
P28482 Mitogen-activated protein kinase 1 Erk C00002743 0 / 0
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002743 3 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00002743 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00002743 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002743 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002743 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002743 0 / 0
P29466 Caspase-1 C14 C00002743 0 / 0
P17252 Protein kinase C alpha type Alpha C00002743 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00002743 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00001178 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002743 2 / 2
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00001430 1 / 4
Q99489 D-aspartate oxidase Enzyme C00001193 0 / 0
P08246 Neutrophil elastase S1A C00002743 2 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00002743 1 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00001178 3 / 1
P00918 Carbonic anhydrase 2 Lyase C00002743 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00002743 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002743 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00002743 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00002743 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00002743 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00002743 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00002743 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00002743 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002743 0 / 0
P02768 Serum albumin Secreted protein C00001151 0 / 0
P08183 Multidrug resistance protein 1 drug C00003666 1 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00002743 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00002743 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00002743 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002743 2 / 2
P14920 D-amino-acid oxidase Enzyme C00001193 0 / 0
P54132 Bloom syndrome protein Enzyme C00001343 1 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00002743 1 / 8
P14416 D(2) dopamine receptor Dopamine receptor C00002743 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002743 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00002743 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00002743 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00002743 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00002743 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00002743 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00002743 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00002743 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00002743 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00002743 1 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002743 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002743 1 / 2
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00002743 0 / 0
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00002743 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001178 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002735 2 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002743 0 / 3
Q8TCC7 Solute carrier family 22 member 8 Antiporter C00001184 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00002743 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00002743 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00002743 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00002743 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00002743 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00002743 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00002743 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00002743 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00002743 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00002743 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00002743 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00002743 1 / 0
P00915 Carbonic anhydrase 1 Lyase C00002743 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00002743 0 / 0
P08311 Cathepsin G S1A C00002743 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002743 1 / 0
P03956 Interstitial collagenase M10A C00002743 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00002743 0 / 0
Q9GZT4 Serine racemase Enzyme C00001193 0 / 0
Q4U2R8 Solute carrier family 22 member 6 Antiporter C00001184 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00002743 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00002743 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00002743 0 / 0
P14679 Tyrosinase Oxidoreductase C00002743 4 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00002743 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00002743 2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00002743 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00002743 1 / 0
P00338 L-lactate dehydrogenase A chain Enzyme C00001193 1 / 5
P21452 Substance-K receptor Neurokinin receptor C00002743 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00001193 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00002743 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00002743 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00002743 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00002743 1 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00002743 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00002743 2 / 1
P21728 D(1A) dopamine receptor Dopamine receptor C00002743 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002743 0 / 1
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00002743 0 / 0
P03372 Estrogen receptor NR3A1 C00002743 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00002743 1 / 0
P22303 Acetylcholinesterase Hydrolase C00002743 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00002743 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00002743 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00002743 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00002743 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00002743 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00002743 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00002743 0 / 0
Q16798 NADP-dependent malic enzyme, mitochondrial Enzyme C00001193 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00002743 3 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00002743 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00002743 5 / 1
Q7Z2H8 Proton-coupled amino acid transporter 1 Unclassified protein C00001343 0 / 0
P10275 Androgen receptor NR3C4 C00000113 3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00002743 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00002743 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00002743 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00002743 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00002743 1 / 1
P07451 Carbonic anhydrase 3 Lyase C00002743 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00002743 0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00002743 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00002743 1 / 1
Q12794 Hyaluronidase-1 Enzyme C00002743 1 / 2
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002743 0 / 0
Q9NSA0 Solute carrier family 22 member 11 Transporter C00001184 0 / 0

47 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00002735 C00002743
9356 SLC22A6, HOAT1, OAT1, PAHT, ROAT1 solute carrier family 22 (organic anion transporter), member 6 C00001178 C00001184
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001430 C00002743
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00002743
182 JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1 jagged 1 C00000094
9818 NUPL1, PRO2463 nucleoporin like 1 C00000094
5142 PDE4B, DPDE4, PDE4B5, PDEIVB phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) C00000094
8544 PIR pirin (iron-binding nuclear protein) (EC:1.13.11.24) C00000094
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00000094
9360 PPIG, CARS-Cyp, CYP, SCAF10, SRCyp peptidylprolyl isomerase G (cyclophilin G) (EC:5.2.1.8) C00000094
5782 PTPN12, PTP-PEST, PTPG1 protein tyrosine phosphatase, non-receptor type 12 (EC:3.1.3.48) C00000094
5774 PTPN3, PTP-H1, PTPH1 protein tyrosine phosphatase, non-receptor type 3 (EC:3.1.3.48) C00000094
6004 RGS16, A28-RGS14, A28-RGS14P, RGS-R regulator of G-protein signaling 16 C00000094
6016 RIT1, NS8, RIBB, RIT, ROC1 Ras-like without CAAX 1 C00000094
6286 S100P, MIG9 S100 calcium binding protein P C00000094
7029 TFDP2, DP2 transcription factor Dp-2 (E2F dimerization partner 2) C00000094
7127 TNFAIP2, B94, EXOC3L3 tumor necrosis factor, alpha-induced protein 2 C00000094
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00000094
7431 VIM, CTRCT30 vimentin C00000094
23621 BACE1, ASP2, BACE, HSPC104 beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) C00002743
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00002743
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00002743
694 BTG1 B-cell translocation gene 1, anti-proliferative C00000094
10681 GNB5, GB5 guanine nucleotide binding protein (G protein), beta 5 C00000094
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002743
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002743
5742 PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00002743
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00002743
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00002743
6319 SCD, FADS5, MSTP008, SCD1, SCDOS stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) C00002743
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00002743
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00002743
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00002743
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00002743
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00000094
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001193
55867 SLC22A11, OAT4, hOAT4 solute carrier family 22 (organic anion/urate transporter), member 11 C00001184
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001430
1553 CYP2A13, CPAD, CYP2A, CYPIIA13 cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1) C00001430
1572 CYP2F1, C2F1, CYP2F cytochrome P450, family 2, subfamily F, polypeptide 1 (EC:1.14.14.1) C00001430
1580 CYP4B1, CYPIVB1, P-450HP cytochrome P450, family 4, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001430
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001430
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001430
3630 INS, IDDM2, ILPR, IRDN, MODY10 insulin C00001151
55630 SLC39A4, AEZ, AWMS2, ZIP4 solute carrier family 39 (zinc transporter), member 4 C00001151
80834 TAS1R2, GPR71, T1R2, TR2 taste receptor, type 1, member 2 C00001151
83756 TAS1R3, T1R3 taste receptor, type 1, member 3 C00001151

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (75)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#600807 Asthma, susceptibility to Q13093
#208900 Ataxia-telangiectasia; at Q13315
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137800 Glioma susceptibility 1; glm1 P04626
#612933 Glycogen storage disease xi; gsd11 P00338
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#147050 Ige responsiveness, atopic; iger Q13093
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#601492 Mucopolysaccharidosis, type ix; mps9 Q12794
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#112100 Yt blood group antigen P22303

KEGG DISEASE (65)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00069 Glycogen storage diseases (GSD) P00338 (related)
H00010 Multiple myeloma P00338 (marker)
H00023 Testicular cancer P00338 (marker)
H00035 Ewing's sarcoma P00338 (marker)
H00043 Neuroblastoma P00338 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00094 DNA repair defects P54132 (related)
Q13315 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00133 Mucopolysaccharidosis type IX (MPS9) Q12794 (related)
H00421 Mucopolysaccharidosis (MPS) Q12794 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)

Diseases related to CTD interactions

21 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008545 Melanoma C00002735
C00002743
D055370 Lung Injury C00001430
D002252 Carbon Tetrachloride Poisoning C00002743
D007249 Inflammation C00002743
D008106 Liver Cirrhosis, Experimental C00002743
D009203 Myocardial Infarction C00002743
D008114 Liver Neoplasms, Experimental C00001584
D012878 Skin Neoplasms C00001584
D001930 Brain Injuries C00001193
D020258 Neurotoxicity Syndromes C00001193
D050197 Atherosclerosis C00002743
D019969 Amphetamine-Related Disorders C00001151
D018149 Glucose Intolerance C00001151
D006461 Hemolysis C00001151
D006946 Hyperinsulinism C00001151
D006948 Hyperkinesis C00001151
D006973 Hypertension C00001151
D007333 Insulin Resistance C00001151
D009401 Nephrosis C00001151
C541083 Non-alcoholic Fatty Liver Disease C00001151
D019966 Substance-Related Disorders C00001151