Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00000091 External link 512 trans-Zeatin
CHEMBL525239
D015026
2 / 3 / 2 0 / 1
C00000093 External link 512 Dihydrozeatin
C00000094 External link 512 2iP
/ N6-(delta2-Isopentenyl)adenine
CHEMBL476189
C001478
5 / 2 / 3 18 / 0
C00007325 External link 512 cis-Zeatin
CHEMBL525239
2 / 3 / 2

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P46063 ATP-dependent DNA helicase Q1 Enzyme C00000091 C00007325 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000091 C00007325 3 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000094 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000094 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000094 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000094 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000094 1 / 0

18 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00000094
694 BTG1 B-cell translocation gene 1, anti-proliferative C00000094
10681 GNB5, GB5 guanine nucleotide binding protein (G protein), beta 5 C00000094
182 JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1 jagged 1 C00000094
9818 NUPL1, PRO2463 nucleoporin like 1 C00000094
5142 PDE4B, DPDE4, PDE4B5, PDEIVB phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) C00000094
8544 PIR pirin (iron-binding nuclear protein) (EC:1.13.11.24) C00000094
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00000094
9360 PPIG, CARS-Cyp, CYP, SCAF10, SRCyp peptidylprolyl isomerase G (cyclophilin G) (EC:5.2.1.8) C00000094
5782 PTPN12, PTP-PEST, PTPG1 protein tyrosine phosphatase, non-receptor type 12 (EC:3.1.3.48) C00000094
5774 PTPN3, PTP-H1, PTPH1 protein tyrosine phosphatase, non-receptor type 3 (EC:3.1.3.48) C00000094
6004 RGS16, A28-RGS14, A28-RGS14P, RGS-R regulator of G-protein signaling 16 C00000094
6016 RIT1, NS8, RIBB, RIT, ROC1 Ras-like without CAAX 1 C00000094
6286 S100P, MIG9 S100 calcium binding protein P C00000094
7029 TFDP2, DP2 transcription factor Dp-2 (E2F dimerization partner 2) C00000094
7127 TNFAIP2, B94, EXOC3L3 tumor necrosis factor, alpha-induced protein 2 C00000094
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00000094
7431 VIM, CTRCT30 vimentin C00000094

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00000091