KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00000113 External link 512 Indole-3-carboxylic acid
CHEMBL387527
C012382
1 / 3 / 4
C00001540 External link 512 6-Hydroxykynurenic acid
C00026494 External link 512 Transtorine
CHEMBL299155
23 / 12 / 17

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00026494 1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00026494 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00026494 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00026494 0 / 1
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00026494 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00026494 0 / 0
O75496 Geminin Unclassified protein C00026494 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00026494 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00026494 0 / 0
P06280 Alpha-galactosidase A Enzyme C00026494 1 / 1
P08138 Tumor necrosis factor receptor superfamily member 16 Membrane receptor C00026494 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00026494 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00026494 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00026494 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00026494 2 / 2
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00026494 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00026494 0 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00026494 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00026494 0 / 0
P10275 Androgen receptor NR3C4 C00000113 3 / 4
Q9UBT6 DNA polymerase kappa Enzyme C00026494 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00026494 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00026494 0 / 0
O00255 Menin Unclassified protein C00026494 2 / 5

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#301500 Fabry disease P06280
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (21)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)