PCIDB

KNApSAcK Metabolite C00001178

Metabolite

KNApSAcK Entry

id C00001178
Name Adipic acid
CAS RN 124-04-9
Standard InChI InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
Standard InChI (Main Layer) InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)

Cluster

Phytochemical cluster
KCF-S cluster No. 1853

Link

ChEMBL

By standard InChI CHEMBL1157
By standard InChI Main Layer CHEMBL1157

KEGG

By LinkDB C06104

CTD

By CAS RN C029900

Species

Summary

Plant class

class name count
eudicotyledons 1

Family

family name count
Amaranthaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Beta vulgaris 161934 Amaranthaceae eudicotyledons Viridiplantae

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 CHEMBL1157 CHEMBL1794524 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL1157 CHEMBL1614544 (1)
11 / 10
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL1157 CHEMBL1794561 (1)
3 / 1
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL1157 CHEMBL1738606 (1)
0 / 0

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C029900 9356 SLC22A6
HOAT1
OAT1
PAHT
ROAT1
solute carrier family 22 (organic anion transporter), member 6 adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]] affects cotreatment
/ decreases reaction
/ increases response to substance
protein 12606766
C029900 9356 SLC22A6
HOAT1
OAT1
PAHT
ROAT1
solute carrier family 22 (organic anion transporter), member 6 adipic acid inhibits the reaction [SLC22A6 protein results in increased transport of 2-amino-3-(2-amino-2-carboxyethylsulfanyl-mercuricsulfanyl)-propionic acid analog] decreases reaction
/ increases transport
protein 15284288

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (11)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)