| Organism name | Pimpinella anisum L. |
|---|---|
| Genus | Pimpinella |
| Family | Apiaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Pimpinella anisum |
|---|---|
| Linked NCBI taxonomy ID | 271192 |
| Linked level | species |
| Family in NCBI taxonomy | Apiaceae |
|---|---|
| ID | 4037 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| Species | Activity |
|---|---|
| Pimpinella anisum L. | Abortifacient |
| Pimpinella anisum L. | Allergenic |
| Pimpinella anisum L. | Analgesic |
| Pimpinella anisum L. | Antibacterial |
| Pimpinella anisum L. | Anticonvulsant |
| Pimpinella anisum L. | Antiseptic |
| Pimpinella anisum L. | Antispasmodic |
| Pimpinella anisum L. | Antiviral |
| Pimpinella anisum L. | Aperitif |
| Pimpinella anisum L. | Aphrodisiac |
| Pimpinella anisum L. | Carminative |
| Pimpinella anisum L. | Collyrium |
| Pimpinella anisum L. | Dentifrice |
| Pimpinella anisum L. | Diaphoretic |
| Pimpinella anisum L. | Emmenagogue |
| Pimpinella anisum L. | Sedative |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00037992
|
Viridoside
|
No. 45 | No. 72 |
|
||||
|
C00037912
|
threo-1'-(4-Hydroxyphenyl)propane 1',2'-diol 4-O-beta-D-glucopyranoside
|
No. 45 | No. 72 |
|
||||
|
C00036335
|
(1'S,2'R)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-beta-D-glucopyranoside
/ (-)-(1'S,2'R)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-beta-D-glucopyranoside |
No. 45 | No. 72 |
|
||||
|
C00019029
|
Tachioside
/ 3-Methoxy-4-hydroxyphenyl-beta-D-glucopyranoside |
CHEMBL1077078
|
No. 45 | No. 72 |
|
|||
|
C00019030
|
Isotachioside
/ Methoxy-hydroquinone-1-O-beta-D-glucopyranoside / 4-Hydroxy-2-methoxyphenyl-beta-D-Glucopyranoside |
No. 45 | No. 72 |
|
||||
|
C00029534
|
4-Hydroxybenzyl beta-D-glucopyranoside
|
No. 45 | No. 72 |
|
||||
|
C00029812
|
Benzyl beta-D-glucopyranoside
/ (-)-Benzyl-O-beta-D-glucopyranoside |
CHEMBL1170453
CHEMBL2336738 |
C410942
|
No. 45 | No. 72 |
|
||
|
C00036331
|
(1'R,2'S)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-beta-D-glucopyranoside
|
No. 45 | No. 72 |
|
||||
|
C00030508
|
Icariside D2
|
No. 45 | No. 72 |
|
||||
|
C00036327
|
(1'R,2'R)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-D-glucopyranoside
|
No. 45 | No. 72 |
|
||||
|
C00036329
|
(1'R,2'R)-Guaiacyl glycerol 4-O-beta-D-glucopyranoside
/ (-)-(1'R,2'R)-Guaiacyl glycerol 4-O-beta-D-glucopyranoside |
No. 45 | No. 72 |
|
||||
|
C00036358
|
(Z)-4-Hydroxy-cinnamyl alcohol 4-O-beta-D-glucopyranoside
|
No. 45 | No. 72 |
|
||||
|
C00037117
|
erythro-1'-(4-Hydroxyphenyl)propane-1',2'-diol 4-O-beta-D-glucopyranoside
|
No. 45 | No. 72 |
|
||||
|
C00036336
|
(1'S,2'S)-Anethole glycol 2'-O-beta-D-glucopyranoside
/ (+)-(1'S,2'S)-Anethole glycol 2'-O-beta-D-glucopyranoside |
No. 45 | No. 72 |
|
||||
|
C00030506
|
Icariside B2
/ (-)-Icariside B2 |
No. 153 |
|
|||||
|
C00037270
|
Hexane-1,5-diol 1-O-beta-D-glucopyranoside
/ (-)-Hexane-1,5-diol 1-O-beta-D-glucopyranoside |
No. 258 | No. 73 |
|
||||
|
C00031877
|
Icariside F2
/ Benzyl beta-D-Apiofuranosyl-(1->6)-O-beta-D-glucopyranoside |
No. 267 |
|
|||||
|
C00031876
|
Icariside D1
|
No. 267 |
|
|||||
|
C00037294
|
Icariside B1
/ (-)-Icariside B1 |
No. 316 |
|
|||||
|
C00001122
|
Glucose
/ D-Glucose / alpha-D-Glucose |
CHEMBL300520
CHEMBL98182 CHEMBL103010 CHEMBL423707 CHEMBL195923 CHEMBL469448 CHEMBL1222152 CHEMBL1222250 CHEMBL1233058 CHEMBL1453070 CHEMBL1519430 CHEMBL1614854 CHEMBL1873035 CHEMBL2093058 CHEMBL2115552 |
26 / 15 / 15 | No. 1283 |
|
|||
|
C00033848
|
Fructose
/ D-Fructose / D-(-)-Fructose |
CHEMBL23894
CHEMBL1869413 |
9 / 4 / 3 | No. 1614 |
|
|||
|
C00037913
|
threo-Anethole glycol
|
CHEMBL553164
|
No. 1736 |
|
||||
|
C00037118
|
erythro-Anethole glycol
|
CHEMBL553164
|
No. 1736 |
|
||||
|
C00036328
|
(1'R,2'R)-Guaiacyl glycerol
/ (-)-(1'R,2'R)-Guaiacyl glycerol |
CHEMBL1078124
|
No. 1736 |
|
||||
|
C00036428
|
1-Deoxythreitol
|
No. 2923 |
|
|||||
|
C00001151
|
Sucrose
/ (+)-Sucrose |
CHEMBL253582
CHEMBL1976550 |
D013395
|
1 / 0 / 0 | 4 / 10 | No. 3949 |
|
|
|
C00035904
|
2-C-Methyl-D-erythritol
|
No. 4667 |
|
|||||
|
C00001163
|
Glycerol
|
CHEMBL692
|
D005990
|
8 / 15 / 11 | 10 / 18 | No. 5926 |
|
|
|
C00036483
|
2-Deoxy-D-ribono-1,4-lactone
|
CHEMBL98888
CHEMBL97916 |
C056405
|
1 / 0 / 0 | No. 7920 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10323 | Acrosin | S1A | C00001122 C00001163 C00033848 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001122 C00033848 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001122 C00001163 | 3 / 1 |
| P07306 | Asialoglycoprotein receptor 1 | Membrane receptor | C00001122 | 0 / 0 |
| Q16773 | Kynurenine--oxoglutarate transaminase 1 | Enzyme | C00001163 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001163 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00033848 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001163 | 11 / 10 |
| P11226 | Mannose-binding protein C | Unclassified protein | C00001122 | 2 / 2 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00033848 | 2 / 0 |
| P02768 | Serum albumin | Secreted protein | C00001151 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00001163 | 1 / 0 |
| P09382 | Galectin-1 | Other cytosolic protein | C00001122 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00033848 | 2 / 3 |
| P11216 | Glycogen phosphorylase, brain form | Enzyme | C00001122 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001163 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00033848 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001122 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00033848 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00001122 | 0 / 0 |
| Q9NNX6 | CD209 antigen | Unclassified protein | C00001122 | 2 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00001122 | 1 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001122 | 0 / 0 |
| P43116 | Prostaglandin E2 receptor EP2 subtype | Prostanoid receptor | C00036483 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00033848 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001122 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001163 | 0 / 0 |
| Q6P4F1 | Alpha-(1,3)-fucosyltransferase 10 | Enzyme | C00001122 | 0 / 0 |
| P17931 | Galectin-3 | Other cytosolic protein | C00001122 | 0 / 1 |
| P11217 | Glycogen phosphorylase, muscle form | Enzyme | C00001122 | 1 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001122 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001122 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00001122 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001122 | 1 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00033848 | 0 / 0 |
| Q9UJ71 | C-type lectin domain family 4 member K | Unclassified protein | C00001122 | 1 / 0 |
| P22897 | Macrophage mannose receptor 1 | Unclassified protein | C00001122 | 0 / 0 |
| Q8WTT0 | C-type lectin domain family 4 member C | Unclassified protein | C00001122 | 0 / 0 |
| Q6EIG7 | C-type lectin domain family 6 member A | Unclassified protein | C00001122 | 0 / 0 |
| P35247 | Pulmonary surfactant-associated protein D | Unclassified protein | C00001122 | 0 / 0 |
| Q9H2X3 | C-type lectin domain family 4 member M | Unclassified protein | C00001122 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 335 | APOA1 | apolipoprotein A-I |
C00001163
|
| 89872 | AQP10, AQPA_HUMAN | aquaporin 10 |
C00001163
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00001163
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00001163
|
| 4489 | MT1A, MT1, MT1S, MTC | metallothionein 1A |
C00001163
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00001163
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00001163
|
| 4878 | NPPA, ANF, ANP, ATFB6, CDD-ANF, PND | natriuretic peptide A |
C00001163
|
| 5443 | POMC, ACTH, CLIP, LPH, MSH, NPP, POC | proopiomelanocortin |
C00001163
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001163
|
| 3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00001151
|
| 55630 | SLC39A4, AEZ, AWMS2, ZIP4 | solute carrier family 39 (zinc transporter), member 4 |
C00001151
|
| 80834 | TAS1R2, GPR71, T1R2, TR2 | taste receptor, type 1, member 2 |
C00001151
|
| 83756 | TAS1R3, T1R3 | taste receptor, type 1, member 3 |
C00001151
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #613393 | Birbeck granule deficiency |
Q9UJ71
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #614371 | Dengue virus, susceptibility to |
Q9NNX6
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232600 | Glycogen storage disease v |
P11217
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #610424 | Hepatitis b virus, susceptibility to |
P11226
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #614372 | Mannose-binding protein deficiency |
P11226
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
Q9NNX6 |
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P11217
(related)
|
| H00105 | Mannose-binding lectin pathway component defects |
P11226
(related)
|
| H00342 | Tuberculosis |
P11226
(related)
P11473 (related) |
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00032 | Thyroid cancer |
P17931
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D058186 | Acute Kidney Injury |
C00001163
|
| D001002 | Anuria |
C00001163
|
| D004195 | Disease Models, Animal |
C00001163
|
| D015812 | Glaucoma, Angle-Closure |
C00001163
|
| D006947 | Hyperkalemia |
C00001163
|
| D007010 | Hyponatremia |
C00001163
|
| D007177 | Inappropriate ADH Syndrome |
C00001163
|
| D007674 | Kidney Diseases |
C00001163
|
| D007683 | Kidney Tubular Necrosis, Acute |
C00001163
|
| D056784 | Leukoencephalopathies |
C00001163
|
| D017202 | Myocardial Ischemia |
C00001163
|
| D009212 | Myoglobinuria |
C00001163
|
| D009336 | Necrosis |
C00001163
|
| D009393 | Nephritis |
C00001163
|
| D051437 | Renal Insufficiency |
C00001163
|
| D012206 | Rhabdomyolysis |
C00001163
|
| D020521 | Stroke |
C00001163
|
| D017180 | Tachycardia, Ventricular |
C00001163
|
| D019969 | Amphetamine-Related Disorders |
C00001151
|
| D018149 | Glucose Intolerance |
C00001151
|
| D006461 | Hemolysis |
C00001151
|
| D006946 | Hyperinsulinism |
C00001151
|
| D006948 | Hyperkinesis |
C00001151
|
| D006973 | Hypertension |
C00001151
|
| D007333 | Insulin Resistance |
C00001151
|
| D009401 | Nephrosis |
C00001151
|
| C541083 | Non-alcoholic Fatty Liver Disease |
C00001151
|
| D019966 | Substance-Related Disorders |
C00001151
|