KCF-S cluster No. 5926 (1 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 2 |
| rosids | 1 |
Cumulative family count
| class name | count |
|---|---|
| Brassicaceae | 1 |
| Apiaceae | 1 |
| Sapotaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001163
|
Glycerol
|
CHEMBL692
|
D005990
|
8 / 15 / 11 | 10 / 18 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10323 | Acrosin | S1A | C00001163 | 0 / 0 |
| Q16773 | Kynurenine--oxoglutarate transaminase 1 | Enzyme | C00001163 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001163 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001163 | 11 / 10 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001163 | 3 / 1 |
| P08183 | Multidrug resistance protein 1 | drug | C00001163 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001163 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001163 | 0 / 0 |
10 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 335 | APOA1 | apolipoprotein A-I |
C00001163
|
| 89872 | AQP10, AQPA_HUMAN | aquaporin 10 |
C00001163
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00001163
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00001163
|
| 4489 | MT1A, MT1, MT1S, MTC | metallothionein 1A |
C00001163
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00001163
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00001163
|
| 4878 | NPPA, ANF, ANP, ATFB6, CDD-ANF, PND | natriuretic peptide A |
C00001163
|
| 5443 | POMC, ACTH, CLIP, LPH, MSH, NPP, POC | proopiomelanocortin |
C00001163
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001163
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
Diseases related to CTD interactions
18 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D058186 | Acute Kidney Injury |
C00001163
|
| D001002 | Anuria |
C00001163
|
| D004195 | Disease Models, Animal |
C00001163
|
| D015812 | Glaucoma, Angle-Closure |
C00001163
|
| D006947 | Hyperkalemia |
C00001163
|
| D007010 | Hyponatremia |
C00001163
|
| D007177 | Inappropriate ADH Syndrome |
C00001163
|
| D007674 | Kidney Diseases |
C00001163
|
| D007683 | Kidney Tubular Necrosis, Acute |
C00001163
|
| D056784 | Leukoencephalopathies |
C00001163
|
| D017202 | Myocardial Ischemia |
C00001163
|
| D009212 | Myoglobinuria |
C00001163
|
| D009336 | Necrosis |
C00001163
|
| D009393 | Nephritis |
C00001163
|
| D051437 | Renal Insufficiency |
C00001163
|
| D012206 | Rhabdomyolysis |
C00001163
|
| D020521 | Stroke |
C00001163
|
| D017180 | Tachycardia, Ventricular |
C00001163
|