KCF-S cluster No. 45 (81 metabolites)

Corresponding Phytochemical cluster No. 72



Metabolite list (81)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001442 External link 512 Dhurrin
CHEMBL469825
C011220
C00001443 External link 512 p-Glucosyloxymandelonitrile
C00001454 External link 512 Prunasin
/ (-)-Prunasin
/ (2R)-Prunasin
/ (-)-(2R)-Prunasin
CHEMBL1778417
C00001460 External link 512 Zierin
C00002638 External link 512 Arbutin
CHEMBL226495
CHEMBL232202
CHEMBL1357990
D001104
5 / 7 / 5 282 / 0
C00002672 External link 512 Salicin
/ Saligenin beta-D-glucopyranoside
CHEMBL334657
CHEMBL462997
CHEMBL1595746
C005696
5 / 1 / 4
C00002706 External link 512 Paeonoside
CHEMBL1079881
C00002707 External link 512 Picein
/ 4-Hydroxyacetophenone 4-glucoside
CHEMBL1512620
C050880
3 / 0 / 0
C00003014 External link 512 Betuloside
/ Rhododendrin
/ (-)-Rhododendrin
CHEMBL1086682
C00019029 External link 512 Tachioside
/ 3-Methoxy-4-hydroxyphenyl-beta-D-glucopyranoside
CHEMBL1077078
C00019030 External link 512 Isotachioside
/ Methoxy-hydroquinone-1-O-beta-D-glucopyranoside
/ 4-Hydroxy-2-methoxyphenyl-beta-D-Glucopyranoside
C00024139 External link 512 Bungeiside A
C080183
C00024140 External link 512 Bungeiside B
C080184
C00029356 External link 512 1-(R)-Phenylethyl beta-D-glucopyranoside
C00029416 External link 512 Picraquassioside D
/ (-)-Picraquassioside D
/ 1-beta-D-Glucopyranosyloxy-3-methoxy-5-hydroxybenzene
C00029468 External link 512 Phenethyl beta-D-glucopyranoside
/ 2-Phenylethyl beta-D-glucopyranoside
/ (-)-Phenethyl beta-D-glucopyranoside
CHEMBL510617
CHEMBL1802183
C00029516 External link 512 Gastrodin
/ (-)-Gastrodin
/ 4-(beta-D-Glucopyranosyloxy) benzyl alcohol
CHEMBL274739
C045345
2 / 2 / 2 0 / 2
C00029534 External link 512 4-Hydroxybenzyl beta-D-glucopyranoside
C00029538 External link 512 Methylarbutin
/ 4-Methoxyphenyl beta-D-glucopyranoside
CHEMBL1173000
CHEMBL1969163
C031919
C00029539 External link 512 4-Methylphenyl beta-D-glucopyranoside
CHEMBL1172859
C00029684 External link 512 Androsin
CHEMBL481234
C071696
C00029812 External link 512 Benzyl beta-D-glucopyranoside
/ (-)-Benzyl-O-beta-D-glucopyranoside
CHEMBL1170453
CHEMBL2336738
C410942
C00029930 External link 512 Chakanoside I
/ Phenacyl beta-D-glucopyranoside
C00030133 External link 512 Dihydroconiferin
CHEMBL460029
C00030192 External link 512 (+)-Betuloside
/ Epirhododendrin
CHEMBL1086682
C00030227 External link 512 Eugenol glucoside
/ Eugenol beta-D-glucopyranoside
CHEMBL463487
C00030466 External link 512 Helicid
/ 4-(beta-D-glucopyranosyloxy) benzaldehyde
CHEMBL201358
CHEMBL461515
C055677
2 / 2 / 2
C00030508 External link 512 Icariside D2
C00030716 External link 512 Manglieside A
C00030898 External link 512 Osmanthuside F
C00030988 External link 512 Phenyl beta-D-glucopyranoside
CHEMBL1172858
C033857
C00031186 External link 512 Rosin
/ Rosin X
/ (-)-Rosin
/ trans-Cinnamyl beta-D-glucopyranoside
C00031274 External link 512 Salidroside
/ Rhodioloside
/ (-)-Rhodioloside
/ Tyrosol alpha-(beta-D-glucopyranoside)
CHEMBL465208
CHEMBL1899113
C009172
3 / 0 / 0
C00031862 External link 512 Homoarbutin
CHEMBL1997201
C00031905 External link 512 Isohomoarbutin
C00032097 External link 512 Orcinol glucoside
/ Orcinol-3-O-beta-D-glycopyranoside
/ (-)-Orcinol-3-O-beta-D-glycopyranoside
CHEMBL1387960
4 / 8 / 3
C00032356 External link 512 Thymol glucoside
/ Thymol-beta-D-glucoside
C00032379 External link 512 Triandrin
C00032471 External link 512 Vanilloloside
CHEMBL468568
1 / 0 / 3
C00032488 External link 512 Vimalin
C00032550 External link 512 Zinolol
C00033088 External link 512 Juniperoside I
/ (-)-Juniperoside I
C00033089 External link 512 Juniperoside II
/ (-)-Juniperoside II
C00033556 External link 512 3,4-Dihydroxyphenethyl glucoside
/ (-)-3,4-Dihydroxyphenethyl glucoside
CHEMBL1689261
1 / 0 / 3
C00033688 External link 512 Calleryanin
C00033723 External link 512 Cimidahurine
C00033891 External link 512 Grevilloside A
/ (-)-Grevilloside A
C00033892 External link 512 Grevilloside B
/ (-)-Grevilloside B
C00033893 External link 512 Grevilloside C
/ (-)-Grevilloside C
C00033894 External link 512 Grevilloside D
/ (-)-Grevilloside D
C00033895 External link 512 Grevilloside E
/ (-)-Grevilloside E
C00034206 External link 512 Sambunigrin
/ (S)-Prunasin
/ (2S)-Sambunigrin
CHEMBL1778417
C00034341 External link 512 Xylaroside A
/ (+)-Xylaroside A
C00034342 External link 512 Xylaroside B
/ (+)-Xylaroside B
C00035111 External link 512 Helicidol
CHEMBL274739
2 / 2 / 2
C00036007 External link 512 3,5-Dihydroxyphenethyl alcohol 3-O-beta-glucopyranoside
CHEMBL2335277
C00036327 External link 512 (1'R,2'R)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-D-glucopyranoside
C00036329 External link 512 (1'R,2'R)-Guaiacyl glycerol 4-O-beta-D-glucopyranoside
/ (-)-(1'R,2'R)-Guaiacyl glycerol 4-O-beta-D-glucopyranoside
C00036331 External link 512 (1'R,2'S)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-beta-D-glucopyranoside
C00036335 External link 512 (1'S,2'R)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-beta-D-glucopyranoside
/ (-)-(1'S,2'R)-1'-(4-Hydroxyphenyl)propane-1',2'-diol 2'-O-beta-D-glucopyranoside
C00036336 External link 512 (1'S,2'S)-Anethole glycol 2'-O-beta-D-glucopyranoside
/ (+)-(1'S,2'S)-Anethole glycol 2'-O-beta-D-glucopyranoside
C00036358 External link 512 (Z)-4-Hydroxy-cinnamyl alcohol 4-O-beta-D-glucopyranoside
C00037117 External link 512 erythro-1'-(4-Hydroxyphenyl)propane-1',2'-diol 4-O-beta-D-glucopyranoside
C00037273 External link 512 Holocalin
C00037535 External link 512 Myzodendrone
C00037912 External link 512 threo-1'-(4-Hydroxyphenyl)propane 1',2'-diol 4-O-beta-D-glucopyranoside
C00037916 External link 512 Thymoquinol 2-O-beta-glucopyranoside
/ (-)-Thymoquinol 2-O-beta-glucopyranoside
C00037917 External link 512 Thymoquinol 5-O-beta-glucopyranoside
/ (-)-Thymoquinol 5-O-beta-glucopyranoside
C00037992 External link 512 Viridoside
C00040127 External link 512 Pyrocatechol-O-beta-D-glucopyranoside
CHEMBL443206
1 / 0 / 3
C00041020 External link 512 Junipediol A 8-glucoside
C00041021 External link 512 Junipediol B 8-glucoside
C00041025 External link 512 Junipetrioloside B
C00041182 External link 512 Taxuside
C00041914 External link 512 Taxiphyllin
CHEMBL469825
C011360
C00045132 External link 512 Vanilloside
C00045259 External link 512 Chavicol beta-D-glucoside
CHEMBL179783
CHEMBL1159496
C00048073 External link 512 Pungenin
CHEMBL1092512
C00048193 External link 512 Terricollene A
/ (+)-Terricollene A
CHEMBL1078078
CHEMBL1077615
C00048194 External link 512 Terricollene B
/ (-)-Terricollene B
CHEMBL1078078
CHEMBL1077615
C00050049 External link 512 Cynanoneside A

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002638 C00002672 C00032471 C00033556 C00040127 0 / 3
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00029516 C00030466 C00035111 1 / 1
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00029516 C00030466 C00035111 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002672 C00032097 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002638 C00032097 1 / 0
O75496 Geminin Unclassified protein C00002707 C00031274 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002707 C00031274 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00032097 7 / 3
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002638 2 / 0
P14679 Tyrosinase Oxidoreductase C00002638 4 / 2
P11216 Glycogen phosphorylase, brain form Enzyme C00002672 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00031274 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002672 0 / 0
O00167 Eyes absent homolog 2 Enzyme C00002707 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002672 1 / 1
P06746 DNA polymerase beta Enzyme C00032097 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002638 0 / 0

282 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
10349 ABCA10, EST698739 ATP-binding cassette, sub-family A (ABC1), member 10 C00002638
154664 ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 C00002638
150000 ABCC13, C21orf73, PRED6 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene C00002638
130013 ACMSD aminocarboxymuconate semialdehyde decarboxylase (EC:4.1.1.45) C00002638
94 ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I activin A receptor type II-like 1 (EC:2.7.11.30) C00002638
8728 ADAM19, MADDAM, MLTNB ADAM metallopeptidase domain 19 C00002638
8748 ADAM20 ADAM metallopeptidase domain 20 C00002638
8756 ADAM7, ADAM_7, ADAM-7, EAPI, GP-83, GP83 ADAM metallopeptidase domain 7 C00002638
9508 ADAMTS3, ADAMTS-4 ADAM metallopeptidase with thrombospondin type 1 motif, 3 (EC:3.4.24.-) C00002638
56999 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 C00002638
155 ADRB3, BETA3AR adrenoceptor beta 3 C00002638
121536 AEBP2 AE binding protein 2 C00002638
60312 AFAP1, AFAP, AFAP-110, AFAP110 actin filament associated protein 1 C00002638
84871 AGBL4, CCP6 ATP/GTP binding protein-like 4 C00002638
56894 AGPAT3, LPAAT-GAMMA1, LPAAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 (EC:2.3.1.51) C00002638
79026 AHNAK, AHNAKRS AHNAK nucleoprotein C00002638
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002638
401138 AMTN, UNQ689 amelotin C00002638
26057 ANKRD17, GTAR, NY-BR-16 ankyrin repeat domain 17 C00002638
200539 ANKRD23, DARP, MARP3 ankyrin repeat domain 23 C00002638
1174 AP1S1, AP19, CLAPS1, MEDNIK, SIGMA1A, WUGSC:H_DJ0747G18.2 adaptor-related protein complex 1, sigma 1 subunit C00002638
55937 APOM, G3a, HSPC336, NG20, apo-M apolipoprotein M C00002638
54840 APTX, AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT aprataxin C00002638
23647 ARFIP2, POR1 ADP-ribosylation factor interacting protein 2 C00002638
9181 ARHGEF2, GEF, GEF-H1, GEFH1, LFP40, P40 Rho/Rac guanine nucleotide exchange factor (GEF) 2 C00002638
402 ARL2, ARFL2 ADP-ribosylation factor-like 2 C00002638
23204 ARL6IP1, AIP1, ARL6IP, ARMER ADP-ribosylation factor-like 6 interacting protein 1 C00002638
170302 ARX, CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS aristaless related homeobox C00002638
55616 ASAP3, ACAP4, CENTB6, DDEFL1, UPLC1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 C00002638
439 ASNA1, ARSA-I, ARSA1, ASNA-I, GET3, TRC40, hASNA-I arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (EC:3.6.3.16) C00002638
83858 ATAD3B, AAA-TOB3, TOB3 ATPase family, AAA domain containing 3B C00002638
1388 ATF6B, CREB-RP, CREBL1, G13 activating transcription factor 6 beta C00002638
338707 B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 (EC:2.4.1.244) C00002638
9529 BAG5, BAG-5 BCL2-associated athanogene 5 C00002638
10286 BCAS2, DAM1, SPF27, Snt309 breast carcinoma amplified sequence 2 C00002638
10295 BCKDK, BCKDKD, BDK branched chain ketoacid dehydrogenase kinase (EC:2.7.11.4) C00002638
658 BMPR1B, ALK-6, ALK6, CDw293 bone morphogenetic protein receptor, type IB (EC:2.7.11.30) C00002638
663 BNIP2, BNIP-2, NIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 C00002638
84446 BRSK1, hSAD1 BR serine/threonine kinase 1 (EC:2.7.11.1 2.7.11.26) C00002638
684 BST2, CD317, TETHERIN bone marrow stromal cell antigen 2 C00002638
11120 BTN2A1, BK14H9.1, BT2.1, BTF1, DJ3E1.1 butyrophilin, subfamily 2, member A1 C00002638
9256 BZRAP1, PBR-IP, PRAX-1, PRAX1, RIM-BP1, RIMBP1 benzodiazapine receptor (peripheral) associated protein 1 C00002638
161502 C15orf26 chromosome 15 open reading frame 26 C00002638
84529 C15orf41, HH114 chromosome 15 open reading frame 41 C00002638
64073 C19orf33, H2RSP, IMUP, IMUP-1, IMUP-2 chromosome 19 open reading frame 33 C00002638
84808 C1orf170, RP11-54O7.8 chromosome 1 open reading frame 170 C00002638
10485 C1orf61, CROC4 chromosome 1 open reading frame 61 C00002638
127795 C1orf87 chromosome 1 open reading frame 87 C00002638
713 C1QB complement component 1, q subcomponent, B chain C00002638
59284 CACNG7 calcium channel, voltage-dependent, gamma subunit 7 C00002638
84290 CAPNS2 calpain, small subunit 2 C00002638
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002638
23466 CBX6 chromobox homolog 6 C00002638
55749 CCAR1, RP11-437A18.1 cell division cycle and apoptosis regulator 1 C00002638
80129 CCDC170, C6orf97, bA282P11.1 coiled-coil domain containing 170 C00002638
79140 CCDC28B, RP4-622L5.5 coiled-coil domain containing 28B C00002638
151195 CCNYL1 cyclin Y-like 1 C00002638
10694 CCT8, C21orf112, Cctq, D21S246, PRED71 chaperonin containing TCP1, subunit 8 (theta) C00002638
977 CD151, GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24 CD151 molecule (Raph blood group) C00002638
11126 CD160, BY55, NK1, NK28 CD160 molecule C00002638
283316 CD163L1, CD163B, M160 CD163 molecule-like 1 C00002638
10421 CD2BP2, FWP010, LIN1, PPP1R59, Snu40, U5-52K CD2 (cytoplasmic tail) binding protein 2 C00002638
917 CD3G, CD3-GAMMA, T3G CD3g molecule, gamma (CD3-TCR complex) C00002638
5127 CDK16, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1 cyclin-dependent kinase 16 (EC:2.7.11.22) C00002638
634 CEACAM1, BGP, BGP1, BGPI carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) C00002638
170482 CLEC4C, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150 C-type lectin domain family 4, member C C00002638
22866 CNKSR2, CNK2, KSR2, MAGUIN connector enhancer of kinase suppressor of Ras 2 C00002638
1308 COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1 collagen, type XVII, alpha 1 C00002638
1360 CPB1, CPB, PASP, PCPB carboxypeptidase B1 (tissue) (EC:3.4.17.2) C00002638
1363 CPE carboxypeptidase E (EC:3.4.17.10) C00002638
57699 CPNE5, COPN5, CPN5 copine V C00002638
113612 CYP2U1, P450TEC, SPG49, SPG56 cytochrome P450, family 2, subfamily U, polypeptide 1 (EC:1.14.14.1) C00002638
326709 C00002638
9879 DDX46, PRPF5, Prp5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 (EC:3.6.4.13) C00002638
1730 DIAPH2, DIA, DIA2, DRF2, POF, POF2 diaphanous-related formin 2 C00002638
22839 DLGAP4, DAP4, DLP4, RP5-977B1.6, SAPAP4 discs, large (Drosophila) homolog-associated protein 4 C00002638
1745 DLX1 distal-less homeobox 1 C00002638
1657 DMXL1 Dmx-like 1 C00002638
56171 DNAH7 dynein, axonemal, heavy chain 7 C00002638
4189 DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049 DnaJ (Hsp40) homolog, subfamily B, member 9 C00002638
29952 DPP7, DPP2, DPPII, QPP dipeptidyl-peptidase 7 (EC:3.4.14.2) C00002638
1808 DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2 dihydropyrimidinase-like 2 C00002638
1889 ECE1, ECE endothelin converting enzyme 1 (EC:3.4.24.71) C00002638
80820 EEPD1, HSPC107 endonuclease/exonuclease/phosphatase family domain containing 1 C00002638
80258 EFHC2, dJ1158H2.1 EF-hand domain (C-terminal) containing 2 C00002638
1944 EFNA3, EFL2, EPLG3, Ehk1-L, LERK3 ephrin-A3 C00002638
10278 EFS, CAS3, CASS3, EFS1, EFS2, HEFS, SIN embryonal Fyn-associated substrate C00002638
79631 EFTUD1, FAM42A, HsT19294, RIA1 elongation factor Tu GTP binding domain containing 1 C00002638
23741 EID1, C15orf3, CRI1, EID-1, IRO45620, PTD014, RBP21 EP300 interacting inhibitor of differentiation 1 C00002638
1991 ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1 elastase, neutrophil expressed (EC:3.4.21.37) C00002638
2018 EMX2 empty spiracles homeobox 2 C00002638
5167 ENPP1, ARHR2, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9) C00002638
2059 EPS8 epidermal growth factor receptor pathway substrate 8 C00002638
8288 EPX, EPO, EPP, EPX-PEN eosinophil peroxidase (EC:1.11.1.7) C00002638
23085 ERC1, Cast2, ELKS, RAB6IP2 ELKS/RAB6-interacting/CAST family member 1 C00002638
711 ERC2-IT1, C1orf1, C3orf51, Po42 ERC2 intronic transcript 1 (non-protein coding) C00002638
2124 EVI2B, CD361, D17S376, EVDB ecotropic viral integration site 2B C00002638
161829 EXD1, EXDL1 exonuclease 3'-5' domain containing 1 C00002638
2165 F13B, FXIIIB coagulation factor XIII, B polypeptide (EC:2.3.2.13) C00002638
131177 FAM3D, EF7, OIT1 family with sequence similarity 3, member D C00002638
51571 FAM49B, L1 family with sequence similarity 49, member B C00002638
115795 FANCD2OS, C3orf24 FANCD2 opposite strand C00002638
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002638
80204 FBXO11, FBX11, PRMT9, UBR6, VIT1 F-box protein 11 C00002638
157574 FBXO16, FBX16 F-box protein 16 C00002638
2250 FGF5, HBGF-5, Smag-82 fibroblast growth factor 5 C00002638
2261 FGFR3, ACH, CD333, CEK2, HSFGFR3EX, JTK4 fibroblast growth factor receptor 3 (EC:2.7.10.1) C00002638
91010 FMNL3, FHOD3, WBP-3, WBP3 formin-like 3 C00002638
8790 FPGT, GFPP fucose-1-phosphate guanylyltransferase (EC:2.7.7.30) C00002638
80144 FRAS1 Fraser syndrome 1 C00002638
9758 FRMPD4, PDZD10, PDZK10 FERM and PDZ domain containing 4 C00002638
2581 GALC galactosylceramidase (EC:3.2.1.46) C00002638
64762 GAREM, C18orf11, FAM59A, Gm944 GRB2 associated, regulator of MAPK1 C00002638
10755 GIPC1, C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2 GIPC PDZ domain containing family, member 1 C00002638
83468 GLT8D2 glycosyltransferase 8 domain containing 2 C00002638
2766 GMPR, GMPR1 guanosine monophosphate reductase (EC:1.7.1.7) C00002638
29889 GNL2, HUMAUANTIG, NGP1, Ngp-1 guanine nucleotide binding protein-like 2 (nucleolar) C00002638
2719 GPC3, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 glypican 3 C00002638
2820 GPD2, GDH2, GPDM, mGPDH glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (EC:1.1.5.3) C00002638
151556 GPR155, DEP.7, DEPDC3, PGR22 G protein-coupled receptor 155 C00002638
2849 GPR26 G protein-coupled receptor 26 C00002638
2854 GPR32, RVDR1 G protein-coupled receptor 32 C00002638
9290 GPR55 G protein-coupled receptor 55 C00002638
55507 GPRC5D G protein-coupled receptor, family C, group 5, member D C00002638
284110 GSDMA, GSDM, GSDM1 gasdermin A C00002638
2977 GUCY1A2, GC-SA2, GUC1A2 guanylate cyclase 1, soluble, alpha 2 (EC:4.6.1.2) C00002638
9421 HAND1, Hxt, Thing1, bHLHa27, eHand heart and neural crest derivatives expressed 1 C00002638
3024 HIST1H1A, H1.1, H1A, H1F1, HIST1 histone cluster 1, H1a C00002638
8334 HIST1H2AC, H2A/l, H2AFL, dJ221C16.4 histone cluster 1, H2ac C00002638
3131 HLF hepatic leukemia factor C00002638
3218 HOXB8, HOX2, HOX2D, Hox-2.4 homeobox B8 C00002638
84343 HPS3, SUTAL Hermansky-Pudlak syndrome 3 C00002638
3283 HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) C00002638
27336 HTATSF1, TAT-SF1, TATSF1, dJ196E23.2 HIV-1 Tat specific factor 1 C00002638
3437 IFIT3, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G interferon-induced protein with tetratricopeptide repeats 3 C00002638
9543 IGDCC3, HsT18880, PUNC immunoglobulin superfamily, DCC subclass, member 3 C00002638
51561 IL23A, IL-23, IL-23A, IL23P19, P19, SGRF interleukin 23, alpha subunit p19 C00002638
3563 IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra interleukin 3 receptor, alpha (low affinity) C00002638
3572 IL6ST, CD130, CDW130, GP130, IL-6RB interleukin 6 signal transducer (gp130, oncostatin M receptor) C00002638
9118 INA, NEF5, NF-66, TXBP-1 internexin neuronal intermediate filament protein, alpha C00002638
8821 INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66) C00002638
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00002638
9196 KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 C00002638
79734 KCTD17 potassium channel tetramerization domain containing 17 C00002638
79070 KDELC1, EP58, KDEL1 KDEL (Lys-Asp-Glu-Leu) containing 1 C00002638
55083 KIF26B kinesin family member 26B C00002638
90293 KLHL13, BKLHD2, KIAA1309 kelch-like family member 13 C00002638
8302 KLRC4, NKG2-F, NKG2F killer cell lectin-like receptor subfamily C, member 4 C00002638
197021 LCTL, KLG, KLPH lactase-like C00002638
56891 LGALS14, CLC2, PPL13 lectin, galactoside-binding, soluble, 14 C00002638
79166 LILRP2, CD85m, ILT10, LILRA5 leukocyte immunoglobulin-like receptor pseudogene 2 C00002638
4041 LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2 low density lipoprotein receptor-related protein 5 C00002638
4040 LRP6, ADCAD2 low density lipoprotein receptor-related protein 6 C00002638
64101 LRRC4, NGL-2 leucine rich repeat containing 4 C00002638
80059 LRRTM4 leucine rich repeat transmembrane neuronal 4 C00002638
7975 MAFK, NFE2U, P18 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K C00002638
11183 MAP4K5, GCKR, KHS, KHS1, MAPKKKK5 mitogen-activated protein kinase kinase kinase kinase 5 (EC:2.7.11.1) C00002638
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00002638
84515 MCM8, C20orf154, dJ967N21.5 minichromosome maintenance complex component 8 (EC:3.6.4.12) C00002638
4188 MDFI, I-MF, I-mfa MyoD family inhibitor C00002638
4239 MFAP4 microfibrillar-associated protein 4 C00002638
90007 MIDN midnolin C00002638
4288 MKI67, KIA, MIB-1 marker of proliferation Ki-67 C00002638
93380 MMGT1, EMC5, TMEM32 membrane magnesium transporter 1 C00002638
245802 MS4A6E membrane-spanning 4-domains, subfamily A, member 6E C00002638
25902 MTHFD1L, FTHFSDC1, MTC1THFS, dJ292B18.2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3) C00002638
4597 MVD, FP17780, MPD mevalonate (diphospho) decarboxylase (EC:4.1.1.33) C00002638
140469 MYO3B myosin IIIB (EC:2.7.11.1) C00002638
83988 NCALD neurocalcin delta C00002638
257194 NEGR1, DMML2433, IGLON4, KILON, Ntra neuronal growth regulator 1 C00002638
129807 NEU4 sialidase 4 (EC:3.2.1.18) C00002638
85407 NKD1, Naked1 naked cuticle homolog 1 (Drosophila) C00002638
9111 NMI N-myc (and STAT) interactor C00002638
122945 NOXRED1, C14orf148 NADP-dependent oxidoreductase domain containing 1 C00002638
7025 NR2F1, COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1 nuclear receptor subfamily 2, group F, member 1 C00002638
8828 NRP2, NP2, NPN2, PRO2714, VEGF165R2 neuropilin 2 C00002638
4909 NTF4, GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5 neurotrophin 4 C00002638
283298 OLFML1, UNQ564 olfactomedin-like 1 C00002638
23762 OSBP2, HLM, ORP-4, ORP4, OSBPL1, OSBPL4 oxysterol binding protein 2 C00002638
114885 OSBPL11, ORP-11, ORP11, OSBP12, TCCCIA00292 oxysterol binding protein-like 11 C00002638
5013 OTX1 orthodenticle homeobox 1 C00002638
11252 PACSIN2, SDPII protein kinase C and casein kinase substrate in neurons 2 C00002638
8505 PARG, PARG99 poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) C00002638
84108 PCGF6, MBLR, RNF134 polycomb group ring finger 6 C00002638
55251 PCMTD2, C20orf36 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 C00002638
80003 PCNXL2 pecanex-like 2 (Drosophila) C00002638
5174 PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1 PDZ domain containing 1 C00002638
5196 PF4, CXCL4, PF-4, SCYB4 platelet factor 4 C00002638
55276 PGM2 phosphoglucomutase 2 (EC:5.4.2.2 5.4.2.7) C00002638
9091 PIGQ, GPI1, c407A10.1 phosphatidylinositol glycan anchor biosynthesis, class Q (EC:2.4.1.198) C00002638
5300 PIN1, DOD, UBL5 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (EC:5.2.1.8) C00002638
23760 PITPNB, PI-TP-beta, PtdInsTP, VIB1B phosphatidylinositol transfer protein, beta C00002638
5314 PKHD1, ARPKD, FCYT, TIGM1 polycystic kidney and hepatic disease 1 (autosomal recessive) C00002638
5427 POLE2, DPE2 polymerase (DNA directed), epsilon 2, accessory subunit (EC:2.7.7.7) C00002638
51535 PPHLN1, HSPC232 periphilin 1 C00002638
5553 PRG2, BMPG, MBP, MBP1 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) C00002638
5613 PRKX, PKX1 protein kinase, X-linked (EC:2.7.11.1) C00002638
3275 PRMT2, HRMT1L1 protein arginine methyltransferase 2 (EC:2.1.1.125) C00002638
285800 PRR18 proline rich 18 C00002638
5396 PRRX1, AGOTC, PHOX1, PMX1, PRX-1, PRX1 paired related homeobox 1 C00002638
5645 PRSS2, TRY2, TRY8, TRYP2 protease, serine, 2 (trypsin 2) (EC:3.4.21.4) C00002638
5719 PSMD13, HSPC027, Rpn9, S11, p40.5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 C00002638
5709 PSMD3, P58, RPN3, S3, TSTA2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 C00002638
22930 RAB3GAP1, P130, RAB3GAP, RAB3GAP130, WARBM1 RAB3 GTPase activating protein subunit 1 (catalytic) C00002638
51560 RAB6B RAB6B, member RAS oncogene family C00002638
153020 RASGEF1B, GPIG4 RasGEF domain family, member 1B C00002638
10739 RFPL2, RNF79 ret finger protein-like 2 C00002638
10738 RFPL3 ret finger protein-like 3 C00002638
727800 RNF208 ring finger protein 208 C00002638
6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2 ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1) C00002638
54665 RSBN1, ROSBIN, RP11-324J2.1 round spermatid basic protein 1 C00002638
6291 SAA4, C-SAA, CSAA serum amyloid A4, constitutive C00002638
51097 SCCPDH, NET11, RP11-439E19.2 saccharopine dehydrogenase (putative) (EC:1.5.1.9) C00002638
6324 SCN1B, ATFB13, BRGDA5, GEFSP1 sodium channel, voltage-gated, type I, beta subunit C00002638
6385 SDC4, SYND4 syndecan 4 C00002638
6406 SEMG1, CT103, SEMG, SGI, dJ172H20.2 semenogelin I C00002638
5104 SERPINA5, PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 C00002638
3053 SERPIND1, D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 C00002638
23451 SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155 splicing factor 3b, subunit 1, 155kDa C00002638
6425 SFRP5, SARP3 secreted frizzled-related protein 5 C00002638
118980 SFXN2 sideroflexin 2 C00002638
6456 SH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4 SH3-domain GRB2-like 2 C00002638
23309 SIN3B SIN3 transcription regulator family member B C00002638
9058 SLC13A2, NADC1, NaCT, NaDC-1, SDCT1 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 C00002638
51296 SLC15A3, OCTP, PHT2, PTR3 solute carrier family 15 (oligopeptide transporter), member 3 C00002638
6571 SLC18A2, SVAT, SVMT, VAT2, VMAT2 solute carrier family 18 (vesicular monoamine transporter), member 2 C00002638
151295 SLC23A3, E2BP3, SVCT3, Yspl1 solute carrier family 23, member 3 C00002638
83884 SLC25A2, ORC2, ORNT2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 C00002638
10999 SLC27A4, ACSVL4, FATP4, IPS solute carrier family 27 (fatty acid transporter), member 4 (EC:6.2.1.-) C00002638
84889 SLC7A3, ATRC3, CAT-3, CAT3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 C00002638
81796 SLCO5A1, OATP-J, OATP-RP4, OATP5A1, OATPRP4, SLC21A15 solute carrier organic anion transporter family, member 5A1 C00002638
79753 SNIP1, PMRED Smad nuclear interacting protein 1 C00002638
122809 SOCS4, SOCS7 suppressor of cytokine signaling 4 C00002638
221178 SPATA13, ARHGEF29, ASEF2 spermatogenesis associated 13 C00002638
64847 SPATA20, SSP411, Tisp78 spermatogenesis associated 20 C00002638
10558 SPTLC1, HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI serine palmitoyltransferase, long chain base subunit 1 (EC:2.3.1.50) C00002638
9754 STARD8, ARHGAP38, DLC3, STARTGAP3 StAR-related lipid transfer (START) domain containing 8 C00002638
85360 SYDE1, 7h3 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) C00002638
8189 SYMPK, SPK, SYM symplekin C00002638
6886 TAL1, SCL, TCL5, bHLHa17, tal-1 T-cell acute lymphocytic leukemia 1 C00002638
23435 TARDBP, ALS10, TDP-43 TAR DNA binding protein C00002638
6938 TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20 transcription factor 12 C00002638
6947 TCN1, TC-1, TC1, TCI transcobalamin I (vitamin B12 binding protein, R binder family) C00002638
26136 TES, TESS, TESS-2 testis derived transcript (3 LIM domains) C00002638
56156 TEX13B, TGC3B, TSGA5 testis expressed 13B C00002638
7043 TGFB3, ARVD, ARVD1, TGF-beta3 transforming growth factor, beta 3 C00002638
7092 TLL1, ASD6, TLL tolloid-like 1 (EC:3.4.24.-) C00002638
25789 TMEM59L, BSMAP, C19orf4 transmembrane protein 59-like C00002638
54863 TOR4A, C9orf167 torsin family 4, member A C00002638
9697 TRAM2 translocation associated membrane protein 2 C00002638
11181 TREH, TRE, TREA trehalase (brush-border membrane glycoprotein) (EC:3.2.1.28) C00002638
7248 TSC1, LAM, TSC tuberous sclerosis 1 C00002638
9819 TSC22D2, TILZ4a, TILZ4b, TILZ4c TSC22 domain family, member 2 C00002638
128553 TSHZ2, C20orf17, OVC10-2, TSH2, ZABC2, ZNF218 teashirt zinc finger homeobox 2 C00002638
118491 TTC18 tetratricopeptide repeat domain 18 C00002638
55001 TTC22 tetratricopeptide repeat domain 22 C00002638
7289 TULP3, TUBL3 tubby like protein 3 C00002638
51619 UBE2D4, HBUCE1 ubiquitin-conjugating enzyme E2D 4 (putative) (EC:6.3.2.19) C00002638
9040 UBE2M, UBC-RS2, UBC12, hUbc12 ubiquitin-conjugating enzyme E2M (EC:6.3.2.19) C00002638
29979 UBQLN1, DA41, DSK2, PLIC-1, UBQN, XDRP1 ubiquilin 1 C00002638
84101 USP44 ubiquitin specific peptidase 44 (EC:3.4.19.12) C00002638
51118 UTP11L, CGI94 UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) C00002638
157680 VPS13B, CHS1, COH1 vacuolar protein sorting 13 homolog B (yeast) C00002638
23339 VPS39, TLP, VAM6, hVam6p vacuolar protein sorting 39 homolog (S. cerevisiae) C00002638
146177 VWA3A von Willebrand factor A domain containing 3A C00002638
126820 WDR63, DIC3, NYD-SP29, RP11-507C22.2 WD repeat domain 63 C00002638
80326 WNT10A, OODD, SSPS, STHAG4 wingless-type MMTV integration site family, member 10A C00002638
9502 XAGE2, CT12.2, GAGED3, XAGE-2 X antigen family, member 2 C00002638
26137 ZBTB20, DPZF, HOF, ODA-8S, ZNF288 zinc finger and BTB domain containing 20 C00002638
51043 ZBTB7B, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX zinc finger and BTB domain containing 7B C00002638
51201 ZDHHC2, DHHC2, ZNF372 zinc finger, DHHC-type containing 2 (EC:2.3.1.225) C00002638
55888 ZKSCAN7, ZFP, ZNF167, ZNF448, ZNF64, ZSCAN39 zinc finger with KRAB and SCAN domains 7 C00002638
7700 ZNF141, D4S90, PAPA6, pHZ-44 zinc finger protein 141 C00002638
162967 ZNF320, ZFPL zinc finger protein 320 C00002638
117608 ZNF354B, KID2 zinc finger protein 354B C00002638
7592 ZNF41, MRX89 zinc finger protein 41 C00002638
84330 ZNF414, ZFP414 zinc finger protein 414 C00002638
158399 ZNF483, ZKSCAN16, ZSCAN48 zinc finger protein 483 C00002638
162968 ZNF497 zinc finger protein 497 C00002638
93474 ZNF670 zinc finger protein 670 C00002638
347344 ZNF81, HFZ20, MRX45, dJ54B20.6 zinc finger protein 81 C00002638
7783 ZP2, ZPA, Zp-2 zona pellucida glycoprotein 2 (sperm receptor) C00002638

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#114500 Colorectal cancer; crc P84022
#613163 Gaba-transaminase deficiency P80404
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649

KEGG DISEASE (11)

KEGG name UniProt
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00029516
D007859 Learning Disorders C00029516