Marsdenia tomentosa
Species
KNApSAcK Entry
| Organism name | Marsdenia tomentosa |
|---|---|
| Genus | Marsdenia |
| Family | Apocynaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Marsdenia tomentosa |
|---|---|
| Linked NCBI taxonomy ID | 276779 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apocynaceae |
|---|---|
| ID | 4056 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (30)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00033180
|
Marstomentoside R
/ (+)-Marstomentoside R |
No. 110 |
|
|||||
|
C00033178
|
Marstomentoside P
/ (+)-Marstomentoside P |
No. 110 |
|
|||||
|
C00033177
|
Marstomentoside O
/ (+)-Marstomentoside O |
No. 110 |
|
|||||
|
C00033168
|
Marstomentoside F
/ (+)-Marstomentoside F |
No. 110 |
|
|||||
|
C00033182
|
Marstomentoside T
/ (+)-Marstomentoside T |
No. 110 |
|
|||||
|
C00033181
|
Marstomentoside S
/ (+)-Marstomentoside S |
No. 110 |
|
|||||
|
C00033167
|
Marstomentoside E
/ (+)-Marstomentoside E |
No. 110 |
|
|||||
|
C00033165
|
Marstomentoside C
/ (+)-Marstomentoside C |
No. 110 |
|
|||||
|
C00033166
|
Marstomentoside D
/ (+)-Marstomentoside D |
No. 110 |
|
|||||
|
C00033164
|
Marstomentoside B
/ (+)-Marstomentoside B |
No. 110 |
|
|||||
|
C00033176
|
Marstomentoside N
/ (+)-Marstomentoside N |
No. 192 |
|
|||||
|
C00033172
|
Marstomentoside J
/ (+)-Marstomentoside J |
No. 192 |
|
|||||
|
C00033169
|
Marstomentoside G
/ (+)-Marstomentoside G |
No. 269 |
|
|||||
|
C00033171
|
Marstomentoside I
/ (+)-Marstomentoside I |
No. 269 |
|
|||||
|
C00033170
|
Marstomentoside H
/ (+)-Marstomentoside H |
No. 269 |
|
|||||
|
C00033163
|
Marstomentoside A
/ (+)-Marstomentoside A |
No. 269 |
|
|||||
|
C00033174
|
Marstomentoside L
/ (+)-Marstomentoside L |
No. 269 |
|
|||||
|
C00033179
|
Marstomentoside Q
/ (+)-Marstomentoside Q |
No. 269 |
|
|||||
|
C00033173
|
Marstomentoside K
/ (+)-Marstomentoside K |
No. 269 |
|
|||||
|
C00033175
|
Marstomentoside M
/ (+)-Marstomentoside M |
No. 385 |
|
|||||
|
C00001164
|
Myoinositol
/ myo-Inositol |
CHEMBL278373
CHEMBL468154 CHEMBL1222251 CHEMBL1231671 CHEMBL1950780 |
8 / 17 / 18 | No. 795 |
|
|||
|
C00048928
|
(-)-Bornesitol
|
CHEMBL171890
CHEMBL501109 CHEMBL493737 CHEMBL460057 |
2 / 1 / 1 | No. 795 |
|
|||
|
C00001174
|
(-)-Viburnitol
|
CHEMBL34244
CHEMBL37104 CHEMBL354060 CHEMBL467977 CHEMBL1950778 |
No. 795 |
|
||||
|
C00001122
|
Glucose
/ D-Glucose / alpha-D-Glucose |
CHEMBL300520
CHEMBL98182 CHEMBL103010 CHEMBL423707 CHEMBL195923 CHEMBL469448 CHEMBL1222152 CHEMBL1222250 CHEMBL1233058 CHEMBL1453070 CHEMBL1519430 CHEMBL1614854 CHEMBL1873035 CHEMBL2093058 CHEMBL2115552 |
26 / 15 / 15 | No. 1283 |
|
|||
|
C00033848
|
Fructose
/ D-Fructose / D-(-)-Fructose |
CHEMBL23894
CHEMBL1869413 |
9 / 4 / 3 | No. 1614 |
|
|||
|
C00048937
|
1-Kestose
|
C072433
|
No. 1765 |
|
||||
|
C00048929
|
(-)-Conduritol F
|
CHEMBL19682
CHEMBL308805 CHEMBL74790 CHEMBL73813 CHEMBL307042 CHEMBL75175 CHEMBL1950779 |
3 / 5 / 7 | No. 3096 |
|
|||
|
C00048968
|
Conduritol A
|
CHEMBL19682
CHEMBL308805 CHEMBL74790 CHEMBL73813 CHEMBL307042 CHEMBL75175 CHEMBL1950779 |
3 / 5 / 7 | No. 3096 |
|
|||
|
C00032853
|
Conduritol F
|
CHEMBL19682
CHEMBL308805 CHEMBL74790 CHEMBL73813 CHEMBL307042 CHEMBL75175 CHEMBL1950779 |
3 / 5 / 7 | No. 3096 |
|
|||
|
C00001151
|
Sucrose
/ (+)-Sucrose |
CHEMBL253582
CHEMBL1976550 |
D013395
|
1 / 0 / 0 | 4 / 10 | No. 3949 |
|
Human Protein / Gene in interactions
41 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P16278 | Beta-galactosidase | Enzyme | C00001164 C00032853 C00048929 C00048968 | 4 / 6 |
| O43451 | Maltase-glucoamylase, intestinal | Hydrolase | C00001164 C00032853 C00048929 C00048968 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00001164 C00032853 C00048929 C00048968 | 1 / 1 |
| P10323 | Acrosin | S1A | C00001122 C00001164 C00033848 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001164 C00033848 C00048928 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001122 C00033848 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001122 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001122 | 3 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001164 | 11 / 10 |
| P02768 | Serum albumin | Secreted protein | C00001151 | 0 / 0 |
| P09382 | Galectin-1 | Other cytosolic protein | C00001122 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00033848 | 2 / 3 |
| P11216 | Glycogen phosphorylase, brain form | Enzyme | C00001122 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00033848 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001122 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00033848 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00001122 | 0 / 0 |
| P07306 | Asialoglycoprotein receptor 1 | Membrane receptor | C00001122 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00048928 | 1 / 1 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00001122 | 1 / 2 |
| P11226 | Mannose-binding protein C | Unclassified protein | C00001122 | 2 / 2 |
| Q9NNX6 | CD209 antigen | Unclassified protein | C00001122 | 2 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001164 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00033848 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001122 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00033848 | 2 / 0 |
| Q6P4F1 | Alpha-(1,3)-fucosyltransferase 10 | Enzyme | C00001122 | 0 / 0 |
| P17931 | Galectin-3 | Other cytosolic protein | C00001122 | 0 / 1 |
| P11217 | Glycogen phosphorylase, muscle form | Enzyme | C00001122 | 1 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001122 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001122 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00001122 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001122 | 1 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00033848 | 0 / 0 |
| Q9UJ71 | C-type lectin domain family 4 member K | Unclassified protein | C00001122 | 1 / 0 |
| P22897 | Macrophage mannose receptor 1 | Unclassified protein | C00001122 | 0 / 0 |
| Q8WTT0 | C-type lectin domain family 4 member C | Unclassified protein | C00001122 | 0 / 0 |
| Q6EIG7 | C-type lectin domain family 6 member A | Unclassified protein | C00001122 | 0 / 0 |
| P35247 | Pulmonary surfactant-associated protein D | Unclassified protein | C00001122 | 0 / 0 |
| Q9H2X3 | C-type lectin domain family 4 member M | Unclassified protein | C00001122 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001164 | 1 / 1 |
4 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00001151
|
| 55630 | SLC39A4, AEZ, AWMS2, ZIP4 | solute carrier family 39 (zinc transporter), member 4 |
C00001151
|
| 80834 | TAS1R2, GPR71, T1R2, TR2 | taste receptor, type 1, member 2 |
C00001151
|
| 83756 | TAS1R3, T1R3 | taste receptor, type 1, member 3 |
C00001151
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (36)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #613393 | Birbeck granule deficiency |
Q9UJ71
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #614371 | Dengue virus, susceptibility to |
Q9NNX6
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #301500 | Fabry disease |
P06280
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232600 | Glycogen storage disease v |
P11217
|
| #230500 | Gm1-gangliosidosis, type i |
P16278
|
| #230600 | Gm1-gangliosidosis, type ii |
P16278
|
| #230650 | Gm1-gangliosidosis, type iii |
P16278
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #610424 | Hepatitis b virus, susceptibility to |
P11226
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #614372 | Mannose-binding protein deficiency |
P11226
|
| #253010 | Mucopolysaccharidosis type ivb |
P16278
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
Q9NNX6 |
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (36)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P11217
(related)
|
| H00105 | Mannose-binding lectin pathway component defects |
P11226
(related)
|
| H00342 | Tuberculosis |
P11226
(related)
P11473 (related) |
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00123 | Mucopolysaccharidosis type IV (MPS4) |
P16278
(related)
|
| H00276 | Galactosialidosis |
P16278
(related)
|
| H00281 | GM1 gangliosidosis |
P16278
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
P16278
(related)
|
| H00422 | Glycoproteinoses |
P16278
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P16278
(related)
|
| H00032 | Thyroid cancer |
P17931
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
10 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D019969 | Amphetamine-Related Disorders |
C00001151
|
| D018149 | Glucose Intolerance |
C00001151
|
| D006461 | Hemolysis |
C00001151
|
| D006946 | Hyperinsulinism |
C00001151
|
| D006948 | Hyperkinesis |
C00001151
|
| D006973 | Hypertension |
C00001151
|
| D007333 | Insulin Resistance |
C00001151
|
| D009401 | Nephrosis |
C00001151
|
| C541083 | Non-alcoholic Fatty Liver Disease |
C00001151
|
| D019966 | Substance-Related Disorders |
C00001151
|