Species

KNApSAcK Entry

Organism name Brassica oleracea
Genus Brassica
Family Cruciferae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Brassica oleracea
Linked NCBI taxonomy ID 3712
Linked level species

Family

Family in NCBI taxonomy Brassicaceae
ID 3700

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (20)

Species Activity
Brassica oleracea L. var. gemmifera Zenker Antiatherosclerotic
Brassica oleracea L. var. gemmifera Zenker Antimaculitic
Brassica oleracea L. var. gemmifera Zenker Antinitrosaminic
Brassica oleracea L. var. gemmifera Zenker Antinyctalopic
Brassica oleracea L. var. gemmifera Zenker Antioxidant
Brassica oleracea L. var. gemmifera Zenker Antiproliferant
Brassica oleracea L. var. gemmifera Zenker Antiradicular
Brassica oleracea L. var. gemmifera Zenker Antiretinitic
Brassica oleracea L. var. gemmifera Zenker Antitumor, breast
Brassica oleracea L. var. gemmifera Zenker Antitumor, colon
Brassica oleracea L. var. gemmifera Zenker Antitumor, lung
Brassica oleracea L. var. gemmifera Zenker Antitumor, skin
Brassica oleracea L. var. gemmifera Zenker Antiviral
Brassica oleracea L. var. gemmifera Zenker Detoxicant
Brassica oleracea L. var. gemmifera Zenker Estrogenic
Brassica oleracea L. var. gemmifera Zenker Glucuronidase-Inhibitor
Brassica oleracea L. var. gemmifera Zenker Goitrogenic
Brassica oleracea L. var. gemmifera Zenker Hypocholesterolemic
Brassica oleracea L. var. gemmifera Zenker Prooxidant
Brassica oleracea L. var. gemmifera Zenker Quinone-Reductase-Inducer

Metabolite list (54)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005646 External link 512 Patuletin 3-gentiobioside
/ Patuletin-3-O-beta-D-gentiobioside
No. 1 No. 15
C00006674 External link 512 Cyanidin 3-sophoroside-5-glucoside
No. 5 No. 15
C00013766 External link 512 Kaempferol 3-sophoroside-7-cellobioside
/ 3-[(2-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-7-[(4-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
No. 5 No. 15
C00006841 External link 512 Cyanidin 3-(6''-malonylsophoroside)-5-glucoside
No. 5 No. 15
C00005229 External link 512 (-)-Kaempferol 3-O-sophoroside 7-O-beta-D-glucopyranoside
/ Kaempferol 3-O-sophoroside 7-O-beta-D-glucopyranoside:Kaempferol 3-sophoroside-7-glucoside
No. 5 No. 15
C00005464 External link 512 Quercetin 3-sophoroside-7-glucoside
/ 2-(3,4-Dihydroxyphenyl)-3-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-one
No. 5 No. 15
C00005997 External link 512 Quercetin 3-[2'''-(E)-feruloylsophoroside]-7-glucoside
No. 7 No. 15
C00005912 External link 512 Kaempferol 3-(2'''-(E)-p-coumarylsophoroside)-7-glucoside
No. 7 No. 15
C00005996 External link 512 Quercetin 3-(2'''-(E)-caffeylsophoroside]-7-glucoside
No. 7 No. 15
C00005916 External link 512 Kaempferol 3-(2'''-sinapylsophoroside)-7-glucoside
No. 7 No. 15
C00005914 External link 512 Kaempferol 3-[2'''-(E)-ferulylsophoroside]-7-glucoside
No. 7 No. 15
C00006848 External link 512 Cyanidin 3-[6''-(4-glucosylferulyl)-sophoroside]-5-glucoside
No. 7 No. 15
C00006846 External link 512 Cyanidin 3-[6''-(4-glucosyl-p-coumaryl)sophoroside]-5-glucoside
No. 7 No. 15
C00005913 External link 512 Kaempferol 3-(2'''-(E)-caffeylsophoroside)-7-glucoside
No. 7 No. 15
C00013805 External link 512 Kaempferol 3-(2'''-(E)-caffeoylglucosyl)-(1->2)-glucoside-7-cellobioside
/ 3-[[2-O-[2-O-[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]-beta-D-glucopyranosyl]oxy]-7-[(4-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
No. 7 No. 15
C00006842 External link 512 Cyanidin 3-(6''-p-coumarylsophoroside)-5-glucoside
No. 7 No. 15
C00006844 External link 512 Cyanidin 3-(6''-ferulylsophoroside)-5-glucoside
No. 7 No. 15
C00006845 External link 512 Cyanidin 3-(6''-sinapylsophoroside)-5-glucoside
No. 7 No. 15
C00007344 External link 512 Glucoerucin
/ 4-Methylthiobutyl glucosinolate
C119493
No. 46 No. 76
C00001488 External link 512 Sinigrin
/ Allyl glucosinolate
/ 2-Phenylethyl glucosinolate
No. 46 No. 76
C00007586 External link 512 Gluconapin
/ 3-Butyl glucosinolate
No. 46 No. 76
C00001486 External link 512 Progoitrin
/ 2(R)-2-Hydroxy 3-butenyl glucosinolate
C009048
No. 46 No. 76
C00001473 External link 512 Glucoiberverin
/ 3-(Methylthio)propyl glucosinolate
No. 46 No. 76
C00001463 External link 512 Glucobrassicanapin
/ 4-Pentenyl glucosinolate
No. 46 No. 76
C00007343 External link 512 Glucoiberin
/ 3-Methylsulfinylpropyl glucosinolate
No. 46 No. 76
C00007545 External link 512 Glucoraphanin
/ 4-Methylsulphinylbutyl glucosinolate
No. 46 No. 76
C00007864 External link 512 Epiprogoitrin
/ 2(S)-2-Hydroxy-3-butenyl glucosinolate
No. 46 No. 76
C00006853 External link 512 Cyanidin 3-(6''-ferulyl-2'''-sinapylsophoroside)-5-glucoside
No. 62 No. 15
C00006851 External link 512 Cyanidin 3-(6''-p-coumaryl-2''-sinapylsophoroside)-5-glucoside
No. 62 No. 15
C00006854 External link 512 Cyanidin 3-(6'',6'''-disinapylsophoroside)-5-glucoside
No. 62 No. 15
C00001260 External link 512 Nonacosane
CHEMBL428955
C047577
No. 115
C00001255 External link 512 Hexacosanol
/ Hexacosan-1-ol
C051942
0 / 2 No. 115
C00001269 External link 512 n-Triacontanol
/ Triacontan-1-ol
CHEMBL1079147
C047578
1 / 0 / 0 No. 115
C00007350 External link 512 Gluconasturtiin
/ 2-Phenylethylglucosinolate
C443697
No. 158 No. 77
C00000127 External link 512 4-Hydroxyglucobrassicin
/ 4-Hydroxy-3-indolylmethylglucosinolate
C036021
No. 158 No. 77
C00000125 External link 512 Glucobrassicin
/ Glucobrassicine
/ 3-Indolylmethylglucosinolate
C048308
2 / 0 No. 158 No. 77
C00000126 External link 512 Neoglucobrassicin
/ 1-Methoxy-3-indolylmethylglucosinolate
C064701
2 / 0 No. 158 No. 77
C00000107 External link 512 IAN
/ Indole-3-acetonitrile
CHEMBL1812654
C016516
No. 710 No. 4
C00000096 External link 512 9-Ribosyl-trans-zeatin
/ Zeatin-9-beta-D-ribofuranoside
No. 989
C00000097 External link 512 N6-(D2-Isopentenyl)-2-methylthioadenosine
/ 2-Methylthio-N6-(delta2-isopentenyl)adenosine
C008503
No. 989
C00002776 External link 512 Sinapic acid
CHEMBL109341
C073734
5 / 5 / 5 0 / 5 No. 1366 No. 6
C00000100 External link 512 IAA
/ Indole-3-acetic acid
CHEMBL82411
C030737
3 / 0 / 0 2 / 1 No. 1432 No. 4
C00050239 External link 512 Sulforaphane
CHEMBL48802
CHEMBL128136
CHEMBL1627201
C016766
5 / 3 / 4 98 / 10 No. 2731
C00033745 External link 512 Cyclobrassinin
No. 3628
C00036440 External link 512 1-Methoxyspirobrassinin
/ (+)-1-Methoxyspirobrassinin
No. 3637
C00001546 External link 512 Methoxybrassinin
/ 1-Methoxybrassinin
No. 3839
C00027106 External link 512 Brassinin
CHEMBL373777
CHEMBL1673034
CHEMBL1673036
CHEMBL1673037
C089020
5 / 7 / 10 No. 3839
C00036583 External link 512 4-Methoxybrassinin
No. 3839
C00001151 External link 512 Sucrose
/ (+)-Sucrose
CHEMBL253582
CHEMBL1976550
D013395
1 / 0 / 0 4 / 10 No. 3949
C00000101 External link 512 IAA methyl ester
/ Methyl indole-3-acetate
No. 4225
C00000112 External link 512 Indole-3-carboxaldehyde
/ 1H-Indole-3-carboxaldehyde
CHEMBL147741
C012381
2 / 1 / 1 No. 4314
C00027108 External link 512 Brassilexin
C430121
No. 5488
C00027107 External link 512 Brassicanal A
No. 5537
C00037061 External link 512 Dioxibrassinin
/ (-)-Dioxibrassinin
No. 6903

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P02768 Serum albumin Secreted protein C00000100 C00001151 0 / 0
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00027106 0 / 0
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002776 3 / 0
Q16773 Kynurenine--oxoglutarate transaminase 1 Enzyme C00000100 0 / 0
P12268 Inosine-5'-monophosphate dehydrogenase 2 Oxidoreductase C00000112 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00001269 0 / 0
P15559 NAD(P)H dehydrogenase [quinone] 1 Enzyme C00050239 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00050239 2 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002776 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00002776 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002776 0 / 3
Q9HBH1 Peptide deformylase, mitochondrial Enzyme C00000100 0 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00050239 1 / 1
P00374 Dihydrofolate reductase Oxidoreductase C00000112 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00050239 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00027106 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00050239 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00027106 0 / 0
O00255 Menin Unclassified protein C00027106 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00027106 1 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002776 0 / 0

106 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000100 C00050239
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00000125 C00050239
710 SERPING1, C1IN, C1INH, C1NH, HAE1, HAE2 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 C00050239
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00050239
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00050239
216 ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH1 aldehyde dehydrogenase 1 family, member A1 (EC:1.2.1.36) C00050239
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00050239
506 ATP5B, ATPMB, ATPSB ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14) C00050239
581 BAX, BCL2L4 BCL2-associated X protein C00050239
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00050239
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00050239
826 CAPNS1, 30K, CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1 calpain, small subunit 1 (EC:3.4.22.17) C00050239
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00050239
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00050239
874 CBR3, SDR21C2, hCBR3 carbonyl reductase 3 (EC:1.1.1.184) C00050239
891 CCNB1, CCNB cyclin B1 C00050239
10576 CCT2, 99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta chaperonin containing TCP1, subunit 2 (beta) C00050239
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00050239
1066 CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1 carboxylesterase 1 (EC:3.1.1.1 3.1.1.56) C00050239
8452 CUL3, CUL-3, PHA2E cullin 3 C00050239
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00050239
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00050239
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00050239
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00050239
1674 DES, CSM1, CSM2, LGMD2R desmin C00050239
1984 EIF5A, EIF-5A, EIF5A1, eIF5AI eukaryotic translation initiation factor 5A C00050239
2072 ERCC4, ERCC11, FANCQ, RAD1, XPF excision repair cross-complementing rodent repair deficiency, complementation group 4 C00050239
2073 ERCC5, COFS3, ERCM2, UVDR, XPG, XPGC excision repair cross-complementing rodent repair deficiency, complementation group 5 C00050239
2078 ERG, erg-3, p55 v-ets avian erythroblastosis virus E26 oncogene homolog C00050239
1647 GADD45A, DDIT1, GADD45 growth arrest and DNA-damage-inducible, alpha C00050239
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00050239
2730 GCLM, GLCLR glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) C00050239
2936 GSR glutathione reductase (EC:1.8.1.7) C00050239
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00050239
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00050239
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00050239
2952 GSTT1 glutathione S-transferase theta 1 (EC:2.5.1.18) C00050239
10013 HDAC6, CPBHM, HD6 histone deacetylase 6 (EC:3.5.1.98) C00050239
221613 HIST1H2AA, H2AA, H2AFR, bA317E16.2 histone cluster 1, H2aa C00050239
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00050239
3185 HNRNPF, HNRPF, OK/SW-cl.23, mcs94-1 heterogeneous nuclear ribonucleoprotein F C00050239
3187 HNRNPH1, HNRPH, HNRPH1, hnRNPH heterogeneous nuclear ribonucleoprotein H1 (H) C00050239
3190 HNRNPK, CSBP, HNRPK, TUNP heterogeneous nuclear ribonucleoprotein K C00050239
3320 HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 heat shock protein 90kDa alpha (cytosolic), class A member 1 C00050239
3305 HSPA1L, HSP70-1L, HSP70-HOM, HSP70T, hum70t heat shock 70kDa protein 1-like C00050239
3308 HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY heat shock 70kDa protein 4 C00050239
3313 HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 heat shock 70kDa protein 9 (mortalin) C00050239
3329 HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13 heat shock 60kDa protein 1 (chaperonin) C00050239
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00050239
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00050239
9118 INA, NEF5, NF-66, TXBP-1 internexin neuronal intermediate filament protein, alpha C00050239
9817 KEAP1, INrf2, KLHL19 kelch-like ECH-associated protein 1 C00050239
354 KLK3, APS, KLK2A1, PSA, hK3 kallikrein-related peptidase 3 (EC:3.4.21.77) C00050239
3956 LGALS1, GAL1, GBP lectin, galactoside-binding, soluble, 1 C00050239
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00050239
5602 MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK mitogen-activated protein kinase 10 (EC:2.7.11.24) C00050239
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00050239
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00050239
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00050239
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00050239
4255 MGMT O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) C00050239
4489 MT1A, MT1, MT1S, MTC metallothionein 1A C00050239
4502 MT2A, MT2 metallothionein 2A C00050239
10397 NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5 N-myc downstream regulated 1 C00050239
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00050239
4830 NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1 NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6) C00050239
283458 C00050239
4851 NOTCH1, TAN1, hN1 notch 1 C00050239
59 ACTA2, AAT6, ACTSA, MYMY5 actin, alpha 2, smooth muscle, aorta C00050239
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00050239
5034 P4HB, DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB prolyl 4-hydroxylase, beta polypeptide (EC:5.3.4.1) C00050239
5111 PCNA proliferating cell nuclear antigen C00050239
10935 PRDX3, AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III peroxiredoxin 3 (EC:1.11.1.15) C00050239
5630 PRPH, NEF4, PRPH1 peripherin C00050239
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00050239
5928 RBBP4, NURF55, RBAP48 retinoblastoma binding protein 4 C00050239
5966 REL, C-Rel v-rel avian reticuloendotheliosis viral oncogene homolog C00050239
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00050239
3921 RPSA, 37LRP, 67LR, LAMBR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, NEM/1CHD4, SA, lamR, p40 ribosomal protein SA C00050239
60 ACTB, BRWS1, PS1TP5BP1 actin, beta C00050239
2810 SFN, YWHAS stratifin C00050239
29986 SLC39A2, 6A1, ETI-1, ZIP-2, ZIP2 solute carrier family 39 (zinc transporter), member 2 C00050239
1155 TBCB, CG22, CKAP1, CKAPI tubulin folding cofactor B C00050239
7168 TPM1, C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA tropomyosin 1 (alpha) C00050239
7846 TUBA1A, B-ALPHA-1, LIS3, TUBA3 tubulin, alpha 1a C00050239
113457 TUBA3D, H2-ALPHA tubulin, alpha 3d C00050239
7277 TUBA4A, H2-ALPHA, TUBA1 tubulin, alpha 4a C00050239
81027 TUBB1 tubulin, beta 1 class VI C00050239
100691897 C00050239
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00050239
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00050239
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00050239
7415 VCP, ALS14, IBMPFD, IBMPFD1, TERA, p97 valosin containing protein (EC:3.6.4.6) C00050239
7431 VIM, CTRCT30 vimentin C00050239
7529 YWHAB, GW128, HS1, KCIP-1, YWHAA tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide C00050239
7531 YWHAE, 14-3-3E, KCIP-1, MDCR, MDS tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide C00050239
10971 YWHAQ, 14-3-3, 1C5, HS1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide C00050239
353088 ZNF429 zinc finger protein 429 C00050239
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00000100
2877 GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9) C00000125
3251 HPRT1, HGPRT, HPRT hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8) C00000126
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000126
3630 INS, IDDM2, ILPR, IRDN, MODY10 insulin C00001151
55630 SLC39A4, AEZ, AWMS2, ZIP4 solute carrier family 39 (zinc transporter), member 4 C00001151
80834 TAS1R2, GPR71, T1R2, TR2 taste receptor, type 1, member 2 C00001151
83756 TAS1R3, T1R3 taste receptor, type 1, member 3 C00001151

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#600807 Asthma, susceptibility to Q13093
#237500 Dubin-johnson syndrome; djs Q92887
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#147050 Ige responsiveness, atopic; iger Q13093
#613839 Megaloblastic anemia due to dihydrofolate reductase deficiency P00374
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (20)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01197 Dihydrofolate reductase (DHFR) deficiency P00374 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00208 Hyperbilirubinemia Q92887 (related)

Diseases related to CTD interactions

25 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00050239
C00000100
C00002776
D003928 Diabetic Nephropathies C00050239
C00001255
D000860 Anoxia C00002776
D006528 Carcinoma, Hepatocellular C00050239
D058186 Acute Kidney Injury C00050239
D011125 Adenomatous Polyposis Coli C00050239
D009336 Necrosis C00050239
D009369 Neoplasms C00050239
D011041 Poisoning C00050239
D002583 Uterine Cervical Neoplasms C00050239
D001745 Urinary Bladder Diseases C00001255
D000647 Amnesia C00002776
D001327 Autoimmune Diseases C00050239
D001930 Brain Injuries C00002776
D004487 Edema C00002776
D019969 Amphetamine-Related Disorders C00001151
D018149 Glucose Intolerance C00001151
D006461 Hemolysis C00001151
D006946 Hyperinsulinism C00001151
D006948 Hyperkinesis C00001151
D006973 Hypertension C00001151
D007333 Insulin Resistance C00001151
D009401 Nephrosis C00001151
C541083 Non-alcoholic Fatty Liver Disease C00001151
D019966 Substance-Related Disorders C00001151