PCIDB

KNApSAcK Metabolite C00000100

Metabolite

KNApSAcK Entry

id C00000100
Name IAA / Indole-3-acetic acid
CAS RN 87-51-4
Standard InChI InChI=1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)
Standard InChI (Main Layer) InChI=1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 1432

Link

ChEMBL

By standard InChI CHEMBL82411
By standard InChI Main Layer CHEMBL82411

KEGG

By LinkDB C00954

CTD

By CAS RN C030737

Species

Summary

Plant class

class name count
rosids 24
Spermatophyta 6
asterids 4
Liliopsida 1
Euphyllophyta 1

Family (Top 10)

family name count
Fabaceae 9
Pinaceae 5
Brassicaceae 3
Rosaceae 3
Fagaceae 2
Rutaceae 2
Solanaceae 2
Euphorbiaceae 2
Hominidae 2
Rhizopodaceae 1

List (39)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Brassica oleracea 3712 Brassicaceae rosids Viridiplantae
Castanea crenata 103480 Fagaceae rosids Viridiplantae
Chamaecyparis lawsoniana 58030 Cupressaceae Spermatophyta Viridiplantae
Citrus sinensis 2711 Rutaceae rosids Viridiplantae
Citrus unshiu 55188 Rutaceae rosids Viridiplantae
Corylus avellana 13451 Betulaceae rosids Viridiplantae
Cotinus coggygria 269719 Anacardiaceae rosids Viridiplantae
Dalbergia dolichopetala 53862 Fabaceae rosids Viridiplantae
Diospyros kaki 35925 Ebenaceae asterids Viridiplantae
Dolichos lablab 35936 Fabaceae rosids Viridiplantae
Euphorbia escula 3977 Euphorbiaceae rosids Viridiplantae
Glycine soja 3848 Fabaceae rosids Viridiplantae
Homo Sapiens 9606 Hominidae Metazoa
Lathyrus maritimus 546224 Fabaceae rosids Viridiplantae
Lycopersicon esculentum 4081 Solanaceae asterids Viridiplantae
Lygodium flexuosum 85330 Lygodiaceae Euphyllophyta Viridiplantae
Malus pumila 283210 Rosaceae rosids Viridiplantae
Nicotiana tabacum 4097 Solanaceae asterids Viridiplantae
Panax ginseng 4054 Araliaceae asterids Viridiplantae
Phaseolus mungo 3915 Fabaceae rosids Viridiplantae
Phaseolus vulgaris 3885 Fabaceae rosids Viridiplantae
Picea abies 3329 Pinaceae Spermatophyta Viridiplantae
Picea sitchensis 3332 Pinaceae Spermatophyta Viridiplantae
Pinus contorta 3339 Pinaceae Spermatophyta Viridiplantae
Pinus slyvestris 3318 Pinaceae Spermatophyta Viridiplantae
Pisum sativum 3888 Fabaceae rosids Viridiplantae
Prunus cerasus 140311 Rosaceae rosids Viridiplantae
Prunus domestica 3758 Rosaceae rosids Viridiplantae
Pseudotsuga menziesii 3357 Pinaceae Spermatophyta Viridiplantae
Quercus robur 38942 Fagaceae rosids Viridiplantae
Raphanus sativus 3726 Brassicaceae rosids Viridiplantae
Rhizopus suinus 64495 Rhizopodaceae Fungi
Ricinus communis 3988 Euphorbiaceae rosids Viridiplantae
Saccharomyces cerevisiae 4932 Saccharomycetaceae Fungi
Vicia amurensis 154495 Fabaceae rosids Viridiplantae
Vigna unguiculata var. sesquipedalis 3913 Fabaceae rosids Viridiplantae
Vitis vinifera 29760 Vitaceae rosids Viridiplantae
Zea mays 4577 Poaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16773 Kynurenine--oxoglutarate transaminase 1 Enzyme CHEMBL82411 CHEMBL1002982 (1)
0 / 0
P02768 Serum albumin Secreted protein CHEMBL82411 CHEMBL894775 (1)
0 / 0
Q9HBH1 Peptide deformylase, mitochondrial Enzyme CHEMBL82411 CHEMBL912248 (1)
0 / 0

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C030737 196 AHR
bHLHe76
aryl hydrocarbon receptor indoleacetic acid results in increased activity of [AHR protein binds to ARNT protein] affects binding
/ increases activity
protein 9407059
C030737 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator indoleacetic acid results in increased activity of [AHR protein binds to ARNT protein] affects binding
/ increases activity
protein 9407059

Related Disease

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D056486 C030737 Drug-Induced Liver Injury therapeutic
19107877