PCIDB

Corylus avellana

Species

KNApSAcK Entry

Organism name Corylus avellana
Genus Corylus
Family Betulaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Corylus avellana
Linked NCBI taxonomy ID 13451
Linked level species

Family

Family in NCBI taxonomy Betulaceae
ID 3514

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (12)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00005397 External link 512 Quercetin 3-glucosyl-(1->2)-galactoside
CHEMBL452919
No. 1 No. 15
C00009116 External link 512 Prodelphinidin B3
/ Gallocatechin-(4alpha->8)-gallocatechin
CHEMBL349509
CHEMBL161013
No. 16 No. 19
C00009111 External link 512 Prodelphinidin C
No. 16 No. 19
C00000001 External link 512 GA1
/ Gibberellin A1
C422660
No. 40 No. 41
C00000009 External link 512 GA9
/ Gibberellin A9
No. 40 No. 41
C00023774 External link 512 Fucostanol
/ Stigmasterol
/ Dihydro-beta-sitosterol
/ (24S)24-Ethylcholestain-3beta-ol
CHEMBL66943
CHEMBL186373
CHEMBL400247
CHEMBL1568947
D013265
5 / 0 / 0 1 / 0 No. 53 No. 11
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00003647 External link 512 Campesterol
/ 24alpha-Methylcholesterol
/ (24R)24-Methylcholest-5-en-3beta-ol
CHEMBL520535
CHEMBL485421
CHEMBL1836653
C021273
No. 53 No. 11
C00036119 External link 512 Gramisterol
No. 111 No. 11
C00007368 External link 512 Obtusifoliol
CHEMBL481434
CHEMBL1978954
C008693
No. 218 No. 51
C00000100 External link 512 IAA
/ Indole-3-acetic acid
CHEMBL82411
C030737
3 / 0 / 0 2 / 1 No. 1432 No. 4
C00000101 External link 512 IAA methyl ester
/ Methyl indole-3-acetate
No. 4225

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00003672 C00023774 0 / 0
P00734 Prothrombin S1A C00003672 4 / 2
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 2 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003672 1 / 0
Q16773 Kynurenine--oxoglutarate transaminase 1 Enzyme C00000100 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003672 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00003672 3 / 2
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00023774 0 / 0
P02768 Serum albumin Secreted protein C00000100 0 / 0
P08183 Multidrug resistance protein 1 drug C00003672 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003672 0 / 1
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00003672 0 / 0
P14679 Tyrosinase Oxidoreductase C00003672 4 / 2
Q9HBH1 Peptide deformylase, mitochondrial Enzyme C00000100 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003672 0 / 0
P03372 Estrogen receptor NR3A1 C00003672 1 / 1
P09884 DNA polymerase alpha catalytic subunit Transferase C00023774 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003672 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003672 0 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 1 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003672 1 / 1
P11388 DNA topoisomerase 2-alpha Isomerase C00023774 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00023774 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000100
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00000100
10599 SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family, member 1B1 C00023774

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#218030 Apparent mineralocorticoid excess; ame P80365
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (12)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00000100