KCF-S cluster No. 218 (29 metabolites)

Corresponding Phytochemical cluster No. 51

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (29)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	28
asterids	10
eudicotyledons	2

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Cumulative family count (Top 20)

class name	count
Euphorbiaceae	23
Coriolaceae	9
Solanaceae	8
Saccharomycetaceae	7
Hymenochaetaceae	5
Davidiellaceae	4
Blastocladiaceae	3
Phaffomycetaceae	2
Physaraceae	2
Betulaceae	2
Ustilaginaceae	2
Cactaceae	2
Pleosporaceae	2
Agaricaceae	2
Sordariaceae	2
Lichtheimiaceae	2
Phycomycetaceae	2
Polyporaceae	1
Hyphochytriaceae	1
Schizophyllaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Dammarenes	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Dammarenes	C08624	C00003745

Metabolite list (29)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003657	Lanosterol / Lanosta-8,24-dien-3beta-ol	CHEMBL225111 CHEMBL465181 CHEMBL1397369	D007810	10 / 17 / 17	1 / 0
C00003745	Euphol / alpha-Euphol / (+)-alpha-Euphol	CHEMBL225111 CHEMBL465181 CHEMBL1397369	C062557	10 / 17 / 17
C00007317	24-Dihydroobtusifoliol		C074062
C00007318	14-Methylfecosterol / 14alpha-Methylergosta-8,24-dien-3beta-ol
C00007319	14alpha-Methyl-delta8-cholestenol
C00007368	Obtusifoliol	CHEMBL481434 CHEMBL1978954	C008693
C00007587	24 1-Methyl-obtusifoliol
C00007588	14-alpha-Methyl-dihydrofecosterol
C00007589	14alpha-24 1-Dimethyl dihydrofecosterol
C00015973	Cladosporide B
C00015974	Cladosporide C
C00015975	Cladosporide D
C00023767	14alpha-Methylzymosterol
C00023775	4alpha,14alpha-Dimethylzymosterol / 4alpha,14alpha-Dimethylcholesta-8,24-dien-3beta-ol
C00023778	Senexonol / 6alpha,22-Dihydroxy-4alpha,14alpha-dimethylcholesta-8,24-dien-3-one
C00023779	Senexadione / 4alpha,14alpha-dimethylcholesta-8,24-diene-3,22-dione
C00023780	Oxidosenexone
C00023781	Lanost-8-en-3beta-ol / 24-Dihydrolanosterol	CHEMBL132906	C015316		1 / 0
C00023794	Eburicodiol / 24-Methylenelanost-8-ene-3beta,21-diol	CHEMBL1765431
C00023795	Eburical / 24-Methylenelanost-8-en-3beta-ol-21-al
C00023805	Eburicol / Obtusifoldienol / 24-Methylene dihydrolanosterol / 24-Methylene-24,25-dihydrolanosterol	CHEMBL518556	C014520
C00023812	23,24,25,26,27-Pentanorlanost-8-ene-3beta,22-diol
C00032839	Cladosporide A
C00033630	Euphorbol / alpha-Euphorbol / gamma-Euphorbol	CHEMBL518556
C00035335	Macdougallin
C00046577	24-Methylenelanosterol
C00048316	Alstonic acid A / (-)-Alstonic acid A
C00048391	Gilvsin A / (+)-Gilvsin A
C00048393	Gilvsin C / (+)-Gilvsin C

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003657 C00003745	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003657 C00003745	11 / 10
Q16850	Lanosterol 14-alpha demethylase	Cytochrome P450 51A1	C00003657 C00003745	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00003657 C00003745	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00003657 C00003745	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003657 C00003745	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003657 C00003745	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003657 C00003745	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00003657 C00003745	4 / 3
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00003657 C00003745	0 / 0

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00023781
1593	CYP27A1, CP27, CTX, CYP27	cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15)	C00003657

Related Diseases

Diseases related to proteins in ChEMBL interactions