KCF-S cluster No. 16 (166 metabolites)

Corresponding Phytochemical cluster No. 19

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (166)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	306
asterids	45
Magnoliophyta	22
Spermatophyta	18
eudicotyledons	11
Liliopsida	9
Euphyllophyta	5

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Cumulative family count (Top 20)

class name	count
Fabaceae	165
Rosaceae	41
Lauraceae	20
Ericaceae	15
Rubiaceae	13
Fagaceae	11
Hippocastanaceae	10
Theaceae	9
Vitaceae	9
Malvaceae	9
Pinaceae	9
Cistaceae	8
Celastraceae	8
Anacardiaceae	8
Salicaceae	8
Arecaceae	7
Ephedraceae	7
Polygonaceae	6
Rhizophoraceae	6
Apocynaceae	5

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Proanthocyanidins	8

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metabolites link (8)

br08003 Category	KEGG ID	KNApSAcK ID
Proanthocyanidins	C10209	C00002906
Proanthocyanidins	C10221	C00002917
Proanthocyanidins	C10227	C00002923
Proanthocyanidins	C10228	C00002924
Proanthocyanidins	C10234	C00002930
Proanthocyanidins	C10237	C00002934
Proanthocyanidins	C10238	C00002935
Proanthocyanidins	C10231	C00009125

Metabolite list (166)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002906	Afzelechin-(4alpha->8)-afzelechin
C00002917	Epicatechin-(4beta->8)-ent-epicatechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914		20 / 7 / 8
C00002923	Prodelphinidin B4 / Gallocatechin-(4alpha->8)-epigallocatechin	CHEMBL349509 CHEMBL161013
C00002924	Gambiriin C
C00002930	Mahuannin D
C00002934	Proanthocyanidin A2 / Proanthocyanidin A-2 / (+)-Proanthocyanidin A-2	CHEMBL286933 CHEMBL81646 CHEMBL450916	C473740	13 / 3 / 4
C00002935	Procyanidin B4 / Catechin-(4alpha->8)-epicatechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914		20 / 7 / 8
C00008900	Isophylloflavanine
C00008901	Phylloflavanine
C00008912	Catechin-(6->6')-catechin
C00008915	Desgalloyl theasinensin F
C00008917	Theasinensin C	CHEMBL264042
C00008919	Catechin-(2'->2')-taxifolin
C00008923	Mesquitol-(5->8)-catechin
C00008924	Mesquitol-(5->5)-mesquitol
C00008925	Mesquitol-(5->6)-mesquitol
C00008928	Gambiriin A1
C00008929	Gambiriin A3
C00008932	Gambiriin B1
C00008933	Gambiriin B3
C00008934	6,7-Dihydro-6-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[3,2-g]fisetinidol
C00008935	6,7-Dihydro-6-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[3,2-g]-ent-epifisetnidol
C00008936	8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]fisetinidol
C00008937	8,9-Dihydro-10-(2,4-dihydroxyphenyl)-9-hydroxy-8-(4-hydroxyphenyl)-10H-pyrano[2,3-h]-ent-fisetinidol
C00008938	8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]-ent-epifisetinidol
C00008939	4'-(2,4-Dihydroxyphenyl)-2'-(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro(2,6')-bis-2H-1-benzopyran3,3',7,8'-tetraol
C00008940	6,7-Dihydro-8-(2,4-dihydroxyphenyl)-6-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[2,3-f]catechin
C00008941	(6S)-6,7-Dihydro-8-(2,4-dihydroxyphenyl)-6-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[2,3-f]epicatechin
C00008942	(6R)-6,7-Dihydro-8-(2,4-dihydroxyphenyl)-6-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[2,3-f]epicatechin
C00008943	6,7-Dihydro-8-(2,4-dihydroxyphenyl)-6-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[2,3-f]-ent-catechin
C00008944	6,7-Dihydro-6-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[3,2-g]catechin
C00008945	6,7-Dihydro-6-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-7-hydroxy-8H-pyrano[3,2-g]epicatechin
C00008946	8,9-Dihydro-8-(2,4-dihydroxyphenyl)-10-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]catechin
C00008947	(10R)-8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]catechin
C00008948	(10S)-8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]catechin
C00008949	(10R)-8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]epicatechin
C00008950	(10S)-8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]epicatechin
C00008951	8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]-ent-catechin
C00008952	8,9-Dihydro-10-(2,4-dihydroxyphenyl)-8-(3,4-dihydroxyphenyl)-9-hydroxy-10H-pyrano[2,3-h]-ent-epicatechin
C00008953	8,9-Dihydro-10-(2,4-dihydroxyphenyl)-9-hydroxy-8-(3,4,5-trihydroxyphenyl)-10H-pyrano[2,3-h]catechin
C00008954	8,9-dihydro-10-(2,4-dihydroxyphenyl)-9-hydroxy-8-(3,4,5-trihydroxyphenyl)-10H-pyrano[2,3-h]gallocatechin
C00008956	Dihydrodaphnodorin B	CHEMBL1532097		19 / 13 / 11
C00008957	Larixinol	CHEMBL481072
C00009034	3,5,7,4'-Tetrahydroxyflavan-(4-O-4)-3,5,7,4'-tetrahydroxyflavan
C00009035	Epimesquitol-(4alpha->O->4beta)-epimesquitol
C00009036	7,3',4'-Trihydroxyflavan-(3->O->4,4->O->3)-7,3',4'-trihydroxyflavan
C00009037	ent-Oritin-(4beta->7,5->6)-epioritin-4alpha-ol
C00009049	Cassiaflavan-(4alpha->6)-epiafzelechin
C00009053	Prodistenidin B2
C00009055	Epiafzelechin-(4beta->8)-epiafzelechin
C00009056	ent-Epiafzeiechin-(4alpha->8)-epiafzelechin
C00009057	3,5,7,4'-Tetrahydroxyflavan-(4->8)-3,4,5,7,4'-pentahydroxyflavan
C00009058	Afzelechin-(4alpha->8)-catechin
C00009059	Epiafzelechin-(4beta->8)-epicatechin
C00009060	ent-Epiafzelechin-(4alpha->8)-epicatechin
C00009061	Ourateaproanthocyanidin A	CHEMBL503797	C013221	2 / 0 / 3	3 / 6
C00009062	Ourateaproanthocyanidin B	CHEMBL503797		2 / 0 / 3
C00009067	Catechin-(4alpha->8)-epiafzelechin	CHEMBL447023		2 / 0 / 3
C00009068	Epicatechin-(4beta->8)-epiafzelechin	CHEMBL447023		2 / 0 / 3
C00009069	ent-Epicatechin-(4alpha->8)-epiafzelechin	CHEMBL447023		2 / 0 / 3
C00009070	Procyanidin B6 / Catechin-(4alpha->6)-catechin	CHEMBL506487 CHEMBL502984 CHEMBL451115
C00009071	Procyanidin B3 / Catechin-(4alpha->8)-catechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914		20 / 7 / 8
C00009072	Catechin-(4beta->8)-catechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914		20 / 7 / 8
C00009073	Procyanidin B8 / Catechin-(4alpha->6)-epicatechin	CHEMBL506487 CHEMBL502984 CHEMBL451115
C00009074	Procyanidin B7 / Catechin-(4beta->6)-catechin	CHEMBL506487 CHEMBL502984 CHEMBL451115
C00009075	Procyanidin B1 / Epicatechin-(4beta->8)-catechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914	C479579	20 / 7 / 8
C00009076	Procyanidin B5 / Epicatechin-(4beta-6)-epicatechin	CHEMBL506487 CHEMBL502984 CHEMBL451115
C00009077	Procyanidin B2 / Epicathechin-(4beta->8)-epicathechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914	C479580	20 / 7 / 8	10 / 0
C00009078	ent-Epicatechin-(4alpha->8)-catechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914		20 / 7 / 8
C00009079	ent-Epicatechin-(4alpha->6)-ent-epicatechin	CHEMBL506487 CHEMBL502984 CHEMBL451115
C00009080	ent-Epicatechin-(4alpha->8)-ent-epicatechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914		20 / 7 / 8
C00009081	Catechin-(4alpha->8)-gallocatechin
C00009082	Catechin-(4alpha->8)-epigallocatechin
C00009110	Gallocatechin-(4alpha->6)-catechin
C00009111	Prodelphinidin C
C00009112	Gallocatechin-(4alpha->8)-epicatechin
C00009113	Epigallocatechin-(4beta->8)-catechin
C00009114	Gallocatechin-(4alpha->6)-gallocatechin
C00009115	Prodelphinidin B5
C00009116	Prodelphinidin B3 / Gallocatechin-(4alpha->8)-gallocatechin	CHEMBL349509 CHEMBL161013
C00009117	Prodelphinidin B1 / Epigallocatechin-(4beta->8)-gallocatechin	CHEMBL349509 CHEMBL161013
C00009118	Prodelphinidin B2 / Epigallocatechin-(4beta->8)-epigallocatechin	CHEMBL349509 CHEMBL161013
C00009123	Guibourtinidol-(4alpha->8)-epiafzelechin
C00009124	Guibourtinidol-(4beta->8)-epiafzelechin
C00009125	Globiflorin 3B2 / Guibourtinidol-(4alpha->6)-catechin
C00009126	Guibourtinidol-(4alpha->8)-catechin
C00009127	Guibourtinidol-(4beta->8)-epicatechin
C00009128	Epiguibourtinidol-(4alpha->8)-epicatechin
C00009129	Guibourtinidol-(4alpha->6)-fisetinidol
C00009130	Guibourtinidol-(4alpha->6)-ent-epifisetinidol
C00009131	Guibourtinidol-(4alpha->8)-fisetinidol
C00009132	Guibourtinidol-(4alpha->6')-fisetinidol
C00009134	Fisetinidol-(4alpha->8)-afzelechin
C00009135	Fisetinidol-(4alpha->6)-catechin
C00009136	ent-Fisetinidol-(4alpha->6)-catechin
C00009137	Fisetinidol-(4alpha->8)-catechin
C00009138	Fisetinidol-(4beta->8)-catechin
C00009139	Fisetinidol-(4alpha->8)-epicatechin
C00009140	Epifisetinidol-(4beta->8)-epicatechin
C00009141	ent-Fisetinidol-(4alpha->8)-catechin
C00009142	ent-Fisetinidol-(4beta->8)-epicatechin
C00009143	Fisetinidol-(4alpha->6)-fisetinidol
C00009144	Fisetinidol-(4alpha->6)-ent-epifisetinidol
C00009145	ent-Epifisetinidol-(4alpha->6)-fisetinidol
C00009146	Fisetinidol-(4alpha->6)-fisetinidol-4alpha-ol
C00009147	Fisetinidol-(4beta->6)-fisetinidol-4alpha-ol
C00009148	Fisetinidol-(4alpha->8)-fisetinidol
C00009149	Fisetinidol-(4beta->6)-robinetinidol
C00009159	Fisetinidol-(4alpha->6)-taxifolin
C00009160	Fisetinidol-(4alpha->6)-ampelopsin
C00009161	Fisetinidol-(4alpha->6')-fisetinidol
C00009162	Fisetinidol-(4beta->6')-fisetinidol
C00009164	Fisetinidol-(4alpha->6')-peltogynan-4alpha-ol
C00009167	Robinetinidol-(4alpha->8)-catechin
C00009168	Robinetinidol-(4beta->8)-catechin
C00009169	Robinetinidol-(4alpha->8)-gallocatechin
C00009170	Robinetinidol-(4beta->6)-robinetinidol-4alpha-ol
C00009174	Robinetinidol-(4alpha->2')-robinetinidol-4alpha-ol
C00009175	Robinetinidol-(4alpha->2')-robinetinidol-4beta-ol
C00009176	Robinetinidol-(4beta->6)-dihydrorobinetin
C00009177	Robinetinidol-(4alpha->8)-dihydrorobinetin
C00009178	Robinetinidol-(4alpha->2')-dihydrorobinetin
C00009182	Epioritin-(4beta->6)-epioritin-4alpha-ol
C00009183	ent-Oritin-(4beta->5)-epioritin-4beta-ol
C00009184	Mesquitol-(4alpha->6)-mesquitol
C00009185	Epimesquitol-(4alpha->6)-epimesquitol-4beta-ol
C00009189	Peltogynane-(4beta->6)-fisetinidol
C00009190	ent-Epipeltogynane-(4alpha->6)-fisetinidol
C00009191	Mopanane-(4beta->6)-fisetinidol
C00009192	Epimopanane-(4beta->6)-fisetinidol
C00009193	ent-Epimopanane-(4alpha->6)-ent-epifisetinidol
C00009194	ent-Epimopanane-(4alpha->8)-fisetinidol
C00009247	Fisetinidol-(4alpha->8)-6-C-methylcatechin
C00009248	Guibourtinidol-(4alpha->6)-catechin-8-carboxylic acid
C00009249	Guibourtinidol-(4alpha->8)-catechin-6-carboxylic acid
C00009250	Epicatechin-(4beta->8)-dryopteric acid
C00009255	Mahuannin C
C00009256	Mahuannin B	CHEMBL447152
C00009257	Epiafzelechin-(2beta->7,4beta->8)-ent-afzelechin	CHEMBL447152
C00009258	ent-Epiafzelechin-(2alpha->7,4alpha->8)-afzelechin	CHEMBL447152
C00009259	Mahuannin A	CHEMBL447152
C00009260	7-O-Methylepiafzelechin-(2beta->7,4beta->8)-epiafzelechin
C00009261	ent-Epiafzelechin-(2alpha->7,4alpha->8)-catechin	CHEMBL1288727
C00009275	Proanthocyanidin A7
C00009276	Proanthocyanidin A6
C00009277	Proanthocyanidin A1	CHEMBL286933 CHEMBL81646 CHEMBL450916		13 / 3 / 4
C00009278	Proanthocyanidin A4	CHEMBL286933 CHEMBL81646 CHEMBL450916		13 / 3 / 4
C00009279	Pavetannin A2	CHEMBL286933 CHEMBL81646 CHEMBL450916		13 / 3 / 4
C00009280	Proanthocyanidin A5'	CHEMBL286933 CHEMBL81646 CHEMBL450916		13 / 3 / 4
C00009281	Pavetannin A1	CHEMBL286933 CHEMBL81646 CHEMBL450916		13 / 3 / 4
C00009282	ent-Epicatechin-(2alpha->7,4alpha->8)-ent-epicatechin	CHEMBL286933 CHEMBL81646 CHEMBL450916		13 / 3 / 4
C00009312	Robinetinidol-(2beta->7,4beta->8)-catechin
C00013271	Epimesquitol-(4beta->4)-epioritin-4beta-ol / (2R,3R,4S)-4-[[(2R,3R,4S)-3,4-Dihydro-3,7,8-trihydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]oxy]-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,7,8-triol
C00013272	Cassiaflavan-(4alpha->8)-epicatechin
C00013274	Butiniflavan-(4beta->8)-epicatechin / (2S,2'R,3'R,4R)-2,2'-bis(3,4-Dihydroxyphenyl)-3,3',4,4'-tetrahydro-[4,8'-bi-2H-1-benzopyran]-3',5',7,7'-tetrol
C00013275	Geranin B / (+)-Geranin B / (2R,3S,8S,14R,15R)- 8-(3,4-Dihydroxyphenyl)-3,4-dihydro-2-(4-hydroxyphenyl)-8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol	CHEMBL499587		3 / 1 / 2
C00013277	Geranin A / (+)-Geranin A	CHEMBL447152
C00013288	Daphnodorin J / (2S)-[3,4,8,9-Tetrahydro-5-hydroxy-2,8-bis(4-hydroxyphenyl)-2H-furo[2,3-h]-1-benzopyran-9-yl](2,4,6-trihydroxyphenyl)methanone
C00020213	6-[1-(3,4-Dihydroxyphenyl)-2-hydroxy-3-(3,4,5-trihydroxyphenyl)propyl]-7,8,3',4'-tetrahydroxyflavan
C00020591	Globiflorin 3B1
C00020668	Robinetidinol(4alpha-6)catechin / [4,6''-Biflavan]-3,3',3'',3''',4',4''',5',5'',7,7''-decol
C00020687	Mesquitol(4alpha->8)catechin
C00030340	Gambiriin A2
C00030341	Gambiriin B2 / (+)-Gambiriin B2
C00036803	bis-8,8'-Catechinylmethane
C00038005	Vitisinol

Human Protein / Gene in interactions

44 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O94806	Serine/threonine-protein kinase D3	Pkd	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
Q05513	Protein kinase C zeta type	Iota	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
P41743	Protein kinase C iota type	Iota	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
P24723	Protein kinase C eta type	Eta	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	1 / 0
Q04759	Protein kinase C theta type	Delta	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 1
P05771	Protein kinase C beta type	Alpha	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	1 / 1
P17252	Protein kinase C alpha type	Alpha	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
Q05655	Protein kinase C delta type	Delta	C00002917 C00002934 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	1 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	3 / 3
P49763	Placenta growth factor	Unclassified protein	C00002934 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282 C00013275	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	0 / 1
P23467	Receptor-type tyrosine-protein phosphatase beta	Receptor tyrosine-protein phosphatase	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	0 / 1
P15692	Vascular endothelial growth factor A	Secreted protein	C00002934 C00009277 C00009278 C00009279 C00009280 C00009281 C00009282 C00013275	1 / 2
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	0 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002917 C00002935 C00009071 C00009072 C00009075 C00009077 C00009078 C00009080	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00009061 C00009062 C00009067 C00009068 C00009069	0 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00009061 C00009062 C00009067 C00009068 C00009069	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00008956	1 / 3
P10696	Alkaline phosphatase, placental-like	Enzyme	C00008956	0 / 1
P45452	Collagenase 3	M10A	C00008956	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00008956	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00008956	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00008956	0 / 0
P08254	Stromelysin-1	M10A	C00008956	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00008956	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00008956	3 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00008956	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00008956	1 / 1
P03956	Interstitial collagenase	M10A	C00008956	0 / 1
P39748	Flap endonuclease 1	Enzyme	C00008956	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00013275	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00008956	2 / 3
P07237	Protein disulfide-isomerase	Enzyme	C00008956	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00008956	2 / 2
P39900	Macrophage metalloelastase	M10A	C00008956	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00008956	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00008956	2 / 1

13 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
729230	CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R	chemokine (C-C motif) receptor 2	C00009061
1232	CCR3, CC-CKR-3, CD193, CKR3, CMKBR3	chemokine (C-C motif) receptor 3	C00009061
1234	CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22	chemokine (C-C motif) receptor 5 (gene/pseudogene)	C00009061
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00009077
581	BAX, BCL2L4	BCL2-associated X protein	C00009077
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00009077
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00009077
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00009077
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00009077
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00009077
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00009077
4240	MFGE8, BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47	milk fat globule-EGF factor 8 protein	C00009077
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00009077

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions