PCIDB

KNApSAcK Metabolite C00009072

Metabolite

KNApSAcK Entry

id C00009072
Name Catechin-(4beta->8)-catechin
CAS RN 51196-37-3
Standard InChI InChI=1S/C30H26O12/c31-13-7-20(37)24-23(8-13)41-29(12-2-4-16(33)19(36)6-12)27(40)26(24)25-21(38)10-17(34)14-9-22(39)28(42-30(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,22,26-29,31-40H,9H2/t22-,26+,27-,28+,29+/m0/s1
Standard InChI (Main Layer) InChI=1S/C30H26O12/c31-13-7-20(37)24-23(8-13)41-29(12-2-4-16(33)19(36)6-12)27(40)26(24)25-21(38)10-17(34)14-9-22(39)28(42-30(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,22,26-29,31-40H,9H2

Cluster

Phytochemical cluster No. 19
KCF-S cluster No. 16

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

20 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1590914 CHEMBL1741321 (1)
1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1590914 CHEMBL1741325 (1)
0 / 1
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase CHEMBL1253314 CHEMBL1252117 (1) CHEMBL1252118 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1590914 CHEMBL1741322 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL1590914 CHEMBL1614227 (1)
3 / 3
P23467 Receptor-type tyrosine-protein phosphatase beta Receptor tyrosine-protein phosphatase CHEMBL1253314 CHEMBL1252119 (1)
0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL1590914 CHEMBL1614240 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1590914 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1590914 CHEMBL1741324 (1)
0 / 1
Q05513 Protein kinase C zeta type Iota CHEMBL81753 CHEMBL769344 (1)
0 / 0
Q04759 Protein kinase C theta type Delta CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 1
Q02156 Protein kinase C epsilon type Eta CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
Q05655 Protein kinase C delta type Delta CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
P05129 Protein kinase C gamma type Alpha CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
1 / 1
P05771 Protein kinase C beta type Alpha CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
P24723 Protein kinase C eta type Eta CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
1 / 0
P41743 Protein kinase C iota type Iota CHEMBL81753 CHEMBL769344 (1)
0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd CHEMBL81753 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723

KEGG DISEASE (8)

KEGG disease name UniProt
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)